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The map label for this gene is gcp [H]

Identifier: 225630410

GI number: 225630410

Start: 695237

End: 696244

Strand: Reverse

Name: gcp [H]

Synonym: WRi_006430

Alternate gene names: 225630410

Gene position: 696244-695237 (Counterclockwise)

Preceding gene: 225630411

Following gene: 225630408

Centisome position: 48.15

GC content: 37.5

Gene sequence:

>1008_bases
ATGAAAACCATTTTAGCTGTTGAAACAAGCTGCGACGAAACTGCAGTAGCGATTGTAAATAGTGACAAGCAAGTCCTTGC
TCACGAAATTCTCTCCCAAGCAGAACACAAAAAACGTGGTGGGGTGATCCCTGAAATAGCTTCACGTGCTCATATGGAGC
ATTTAAGTGGTCTAATAAAAAGCGCCGTGGAAAAATCTAACCTTAACTTTTGTGACCTCAATGCAATTGCAGCAACATCA
GGACCAGGACTCATAGGTGGATTAATAGTTGGTACAATGATGGCTAAAGCAATTGCGCATGTAGCACAAAAACCATTCAT
TGCAGTGAATCACTTAGAAGCGCATGCATTGGTTATTAGGTTACTGCATGAGGTAAAATTTCCATTTTTAGTCCTACTAA
TATCAGGTGGTCACTGTCAATTTTTAATTGCACAGGATGTAGGTAAATACATTAAACTTGGAGAAACGCTCGATGATTCA
CTAGGAGAAGCATTTGATAAAGTTGCTAAGATGCTGGGTTTAAGCTATCCCGGAGGGCCATTAATTGAAAAGTTAGCTAA
AAAAGGCAATGGTGCAAGATTTAAATTGCCAAGGGCAATGATAAAACGTTATGGATGTAACTTTTCGTTTTCTGGAATTA
AAACAGCAGTAAAAAACTTAGTGCAAGAACTTAAAATGAGCGAGCAAGATGTGTGTGATGTATGTGCTTCGTTTCAAGAG
TGTATTAGTGACATACTGCTGGACAGGGTTAGTAATGCGATTATTATGGCCGAATCTTTAAATATCAAAATCAATGACTT
TGTGATTACCGGCGGAGTTGCAGCAAATAATTTCTTGAGAGAAAAATTAAAACAACACATAAACTTAAACATATTTTTTC
CCCCTAACGACCTATGTACAGACAATGCAATTATGGTTGGATGGACAGGAATTGAAAGGTTACAGAAAAATTATATAGAT
CCACTTAATTTTGCACCAAGACCTAAGTGGGAGTTAGAGAGTTATTAA

Upstream 100 bases:

>100_bases
GACGGTTGTCGGTAAATCTTTTAGCTGTAGAAGTTAACTTTGCAGTTAACTTCTACAGCGTTTCAAGATATAGTTTTGAT
AATAAAGTGCTCGAATATAC

Downstream 100 bases:

>100_bases
AAGCTCTCAATTCTGAATTATAGCTAAAGTGACTTAGGTTCTCTAATTGCACATAAGTCAACAATAATTTTCACACAAAT
CAAAACAGCATATCTTCTCC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKTILAVETSCDETAVAIVNSDKQVLAHEILSQAEHKKRGGVIPEIASRAHMEHLSGLIKSAVEKSNLNFCDLNAIAATS
GPGLIGGLIVGTMMAKAIAHVAQKPFIAVNHLEAHALVIRLLHEVKFPFLVLLISGGHCQFLIAQDVGKYIKLGETLDDS
LGEAFDKVAKMLGLSYPGGPLIEKLAKKGNGARFKLPRAMIKRYGCNFSFSGIKTAVKNLVQELKMSEQDVCDVCASFQE
CISDILLDRVSNAIIMAESLNIKINDFVITGGVAANNFLREKLKQHINLNIFFPPNDLCTDNAIMVGWTGIERLQKNYID
PLNFAPRPKWELESY

Sequences:

>Translated_335_residues
MKTILAVETSCDETAVAIVNSDKQVLAHEILSQAEHKKRGGVIPEIASRAHMEHLSGLIKSAVEKSNLNFCDLNAIAATS
GPGLIGGLIVGTMMAKAIAHVAQKPFIAVNHLEAHALVIRLLHEVKFPFLVLLISGGHCQFLIAQDVGKYIKLGETLDDS
LGEAFDKVAKMLGLSYPGGPLIEKLAKKGNGARFKLPRAMIKRYGCNFSFSGIKTAVKNLVQELKMSEQDVCDVCASFQE
CISDILLDRVSNAIIMAESLNIKINDFVITGGVAANNFLREKLKQHINLNIFFPPNDLCTDNAIMVGWTGIERLQKNYID
PLNFAPRPKWELESY
>Mature_335_residues
MKTILAVETSCDETAVAIVNSDKQVLAHEILSQAEHKKRGGVIPEIASRAHMEHLSGLIKSAVEKSNLNFCDLNAIAATS
GPGLIGGLIVGTMMAKAIAHVAQKPFIAVNHLEAHALVIRLLHEVKFPFLVLLISGGHCQFLIAQDVGKYIKLGETLDDS
LGEAFDKVAKMLGLSYPGGPLIEKLAKKGNGARFKLPRAMIKRYGCNFSFSGIKTAVKNLVQELKMSEQDVCDVCASFQE
CISDILLDRVSNAIIMAESLNIKINDFVITGGVAANNFLREKLKQHINLNIFFPPNDLCTDNAIMVGWTGIERLQKNYID
PLNFAPRPKWELESY

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=336, Percent_Identity=37.5, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI8923380, Length=329, Percent_Identity=29.1793313069909, Blast_Score=119, Evalue=3e-27,
Organism=Escherichia coli, GI1789445, Length=334, Percent_Identity=39.5209580838323, Blast_Score=269, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17557464, Length=326, Percent_Identity=34.0490797546012, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI71995670, Length=320, Percent_Identity=28.4375, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320099, Length=363, Percent_Identity=29.7520661157025, Blast_Score=161, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6322891, Length=296, Percent_Identity=28.3783783783784, Blast_Score=92, Evalue=9e-20,
Organism=Drosophila melanogaster, GI20129063, Length=344, Percent_Identity=34.0116279069767, Blast_Score=197, Evalue=6e-51,
Organism=Drosophila melanogaster, GI21357207, Length=339, Percent_Identity=28.9085545722714, Blast_Score=124, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36681; Mature: 36681

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTILAVETSCDETAVAIVNSDKQVLAHEILSQAEHKKRGGVIPEIASRAHMEHLSGLIK
CCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SAVEKSNLNFCDLNAIAATSGPGLIGGLIVGTMMAKAIAHVAQKPFIAVNHLEAHALVIR
HHHHHCCCCEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHH
LLHEVKFPFLVLLISGGHCQFLIAQDVGKYIKLGETLDDSLGEAFDKVAKMLGLSYPGGP
HHHHHCCCEEEEEECCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCH
LIEKLAKKGNGARFKLPRAMIKRYGCNFSFSGIKTAVKNLVQELKMSEQDVCDVCASFQE
HHHHHHHCCCCCEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
CISDILLDRVSNAIIMAESLNIKINDFVITGGVAANNFLREKLKQHINLNIFFPPNDLCT
HHHHHHHHHHCCCEEEEECCCEEEEEEEEECCHHHHHHHHHHHHHHCCEEEEECCCCCCC
DNAIMVGWTGIERLQKNYIDPLNFAPRPKWELESY
CCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTILAVETSCDETAVAIVNSDKQVLAHEILSQAEHKKRGGVIPEIASRAHMEHLSGLIK
CCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SAVEKSNLNFCDLNAIAATSGPGLIGGLIVGTMMAKAIAHVAQKPFIAVNHLEAHALVIR
HHHHHCCCCEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHH
LLHEVKFPFLVLLISGGHCQFLIAQDVGKYIKLGETLDDSLGEAFDKVAKMLGLSYPGGP
HHHHHCCCEEEEEECCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCH
LIEKLAKKGNGARFKLPRAMIKRYGCNFSFSGIKTAVKNLVQELKMSEQDVCDVCASFQE
HHHHHHHCCCCCEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
CISDILLDRVSNAIIMAESLNIKINDFVITGGVAANNFLREKLKQHINLNIFFPPNDLCT
HHHHHHHHHHCCCEEEEECCCEEEEEEEEECCHHHHHHHHHHHHHHCCEEEEECCCCCCC
DNAIMVGWTGIERLQKNYIDPLNFAPRPKWELESY
CCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA