Click here to switch to the map view.

The map label for this gene is ppiD [H]

Identifier: 225630407

GI number: 225630407

Start: 688406

End: 690205

Strand: Direct

Name: ppiD [H]

Synonym: WRi_006380

Alternate gene names: 225630407

Gene position: 688406-690205 (Clockwise)

Preceding gene: 225630404

Following gene: 225630409

Centisome position: 47.61

GC content: 33.39

Gene sequence:

>1800_bases
ATGAATGTTAAAAATTTTTTCACTAAAGTAACTGTTGTCCTTTTAGCTTGCTTGTTAATCTTTGTGGGAGTTGGCAACCT
TTTATCAGGTGATGATGAAAAAGAAGAGGTAGCTAGGGTTGGAAAAGAAGTTATAACGTCAGATGAGTATAAATCACTAT
ATCAAAATTATGGAAAACAAATTTCTGGATCTGATGCGAGTAGAGAACAAGTAAAAAAGCTGAAATATGATTTACTTAAC
GCACTTATAGAGCAAAAACTATTGTTTAACCTAACTAGTGAACTGGGGTTGACAGTTGGAGAAGAGTCTATAAAAAACCA
TATTAAAAACACCAAGTACTTTCAAAATGATAAAGGCGAATTTGACAAAAACAAATTCCATGAAACGCTAAATGACCTGC
ATATGACAGAGAAAGAGTATATAGCAAAGCTAGAGAAAATCCTGCCTGCAATGATGTTTATGACTTCGTTATTTAAAGAT
AATTATCCGGTAACTTTTGGCGAGAAAATTGATGAGCAGATATACAACAGTCGCTACCAAACTAGAGTAGTTGATATTGT
TAAGATAACTGAAGATGCAGTTACAAACATTCCTGAACCAGATGATCAAACCTTACTTGATTTGTACGAAAGAAATAAAT
CCCATTTTTATTATCCTGAGTATCGAACTGCGCAATATATTTCTCTAGAACAGAAATATTTTGAAGATCAAATCAAGATC
TCAGATGAAGAAGTTGATGGCATAATAGAACAACAAGAACTTAGAGATCAAAGAGACATATTTAATATAATATTTTCTAC
CAAAGAAGAAGCTGAGACAGCAAGAAGAGCATTTGAGGAGGGTAAAACAAGCTTTGAACAGATAGTAGAAGAGTTTGGCA
AAGCAGAACTTGAAGAAACTAGAGTAAATAATATAACTAAGGATTTTCTACCGGAAGACATGAGAGAGAAGGTGTTTGCT
CTTAAAGTAGGTGAAGTAAGTGAAGTTTTAGCAAGCAGTTTTGGTTGGCACATAATAAAAGTGGAAAGTGCGCATCAAAT
CTCTGATGAAGACTTAGTTGATTTAAAAAAAGACATAAAGTCAGTTTTAACTAACCAAAAGTCTTTTGAAAGAGTCAATG
ATTTCATAAACCAAGTGAACTATAAGATATACAATGGTTCAGCAATCGAAGAAATATTGAGTGAATATAATTTACCTATA
CAAACTATTGGTCCAGTAGATGCGAGTGGAAAAGATCAAAGCGGTAATAACGTAGGAGATTCTAGTGATTTGATTTCTTT
CATTTTTTCGCGAGAAAAGGATCAGAAAGGTTATTTTAAGGGCGTTGGGGACGCTGTTGTTAGTGTAAAAATCATCGATA
TCGTTCCACCTAAATCACAAAGTTTTGAAGAAGGCAGGGCATCAGCAGTAGAGCTTTGGCAGAGTGAGTTTATAAAAGAA
AGAATGTTTAAAATTGGGCAAGAGTTTGCAGTTCAACTAAGAGAAAAAACAGATTGGGAAAAAATTCAAGGTGTGGAATT
AGTTGAAGATCAGCAGATGCATCGCAATGAACAAAACTACCCATTTTCTTTTGTAGAAGAGATTTTCAATATGAAAACAA
CTGGTTCAGTGACAGACCCTATTCAATACAATAATGAAATTATAATAGGTGTTCTAAAAGAAATGCATTCATCAAATGGC
AAATTAAACATGCTTGACACCGGAAAACGTGTGATGATATCGCTAAAAGAGCAATTAATTAGCTATCTGGAATCAAAGTA
TAAAGTCGAAGTTAATCACGCTATACTTGATGATATATAA

Upstream 100 bases:

>100_bases
TTAAGTTAATATATTATATATATTATCTAATAAAGCAACAGGTTTACAAGTATTAAATTATCACTATTCTATAATTAACC
ATTAATTAACTGAGTTTAAA

Downstream 100 bases:

>100_bases
TCAAAAATCTTATAAGCTGCTTCAAACGCATCCAGTGCCCAGACACACAACTGTACGAACATTGCGATTTGAGAGCAATC
TTCACTAGAAAAGATACCGT

Product: peptidyl-prolyl cis-trans isomerse D, putative

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MNVKNFFTKVTVVLLACLLIFVGVGNLLSGDDEKEEVARVGKEVITSDEYKSLYQNYGKQISGSDASREQVKKLKYDLLN
ALIEQKLLFNLTSELGLTVGEESIKNHIKNTKYFQNDKGEFDKNKFHETLNDLHMTEKEYIAKLEKILPAMMFMTSLFKD
NYPVTFGEKIDEQIYNSRYQTRVVDIVKITEDAVTNIPEPDDQTLLDLYERNKSHFYYPEYRTAQYISLEQKYFEDQIKI
SDEEVDGIIEQQELRDQRDIFNIIFSTKEEAETARRAFEEGKTSFEQIVEEFGKAELEETRVNNITKDFLPEDMREKVFA
LKVGEVSEVLASSFGWHIIKVESAHQISDEDLVDLKKDIKSVLTNQKSFERVNDFINQVNYKIYNGSAIEEILSEYNLPI
QTIGPVDASGKDQSGNNVGDSSDLISFIFSREKDQKGYFKGVGDAVVSVKIIDIVPPKSQSFEEGRASAVELWQSEFIKE
RMFKIGQEFAVQLREKTDWEKIQGVELVEDQQMHRNEQNYPFSFVEEIFNMKTTGSVTDPIQYNNEIIIGVLKEMHSSNG
KLNMLDTGKRVMISLKEQLISYLESKYKVEVNHAILDDI

Sequences:

>Translated_599_residues
MNVKNFFTKVTVVLLACLLIFVGVGNLLSGDDEKEEVARVGKEVITSDEYKSLYQNYGKQISGSDASREQVKKLKYDLLN
ALIEQKLLFNLTSELGLTVGEESIKNHIKNTKYFQNDKGEFDKNKFHETLNDLHMTEKEYIAKLEKILPAMMFMTSLFKD
NYPVTFGEKIDEQIYNSRYQTRVVDIVKITEDAVTNIPEPDDQTLLDLYERNKSHFYYPEYRTAQYISLEQKYFEDQIKI
SDEEVDGIIEQQELRDQRDIFNIIFSTKEEAETARRAFEEGKTSFEQIVEEFGKAELEETRVNNITKDFLPEDMREKVFA
LKVGEVSEVLASSFGWHIIKVESAHQISDEDLVDLKKDIKSVLTNQKSFERVNDFINQVNYKIYNGSAIEEILSEYNLPI
QTIGPVDASGKDQSGNNVGDSSDLISFIFSREKDQKGYFKGVGDAVVSVKIIDIVPPKSQSFEEGRASAVELWQSEFIKE
RMFKIGQEFAVQLREKTDWEKIQGVELVEDQQMHRNEQNYPFSFVEEIFNMKTTGSVTDPIQYNNEIIIGVLKEMHSSNG
KLNMLDTGKRVMISLKEQLISYLESKYKVEVNHAILDDI
>Mature_599_residues
MNVKNFFTKVTVVLLACLLIFVGVGNLLSGDDEKEEVARVGKEVITSDEYKSLYQNYGKQISGSDASREQVKKLKYDLLN
ALIEQKLLFNLTSELGLTVGEESIKNHIKNTKYFQNDKGEFDKNKFHETLNDLHMTEKEYIAKLEKILPAMMFMTSLFKD
NYPVTFGEKIDEQIYNSRYQTRVVDIVKITEDAVTNIPEPDDQTLLDLYERNKSHFYYPEYRTAQYISLEQKYFEDQIKI
SDEEVDGIIEQQELRDQRDIFNIIFSTKEEAETARRAFEEGKTSFEQIVEEFGKAELEETRVNNITKDFLPEDMREKVFA
LKVGEVSEVLASSFGWHIIKVESAHQISDEDLVDLKKDIKSVLTNQKSFERVNDFINQVNYKIYNGSAIEEILSEYNLPI
QTIGPVDASGKDQSGNNVGDSSDLISFIFSREKDQKGYFKGVGDAVVSVKIIDIVPPKSQSFEEGRASAVELWQSEFIKE
RMFKIGQEFAVQLREKTDWEKIQGVELVEDQQMHRNEQNYPFSFVEEIFNMKTTGSVTDPIQYNNEIIIGVLKEMHSSNG
KLNMLDTGKRVMISLKEQLISYLESKYKVEVNHAILDDI

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=369, Percent_Identity=24.390243902439, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 69099; Mature: 69099

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVKNFFTKVTVVLLACLLIFVGVGNLLSGDDEKEEVARVGKEVITSDEYKSLYQNYGKQ
CCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCC
ISGSDASREQVKKLKYDLLNALIEQKLLFNLTSELGLTVGEESIKNHIKNTKYFQNDKGE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCC
FDKNKFHETLNDLHMTEKEYIAKLEKILPAMMFMTSLFKDNYPVTFGEKIDEQIYNSRYQ
CCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHH
TRVVDIVKITEDAVTNIPEPDDQTLLDLYERNKSHFYYPEYRTAQYISLEQKYFEDQIKI
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHCC
SDEEVDGIIEQQELRDQRDIFNIIFSTKEEAETARRAFEEGKTSFEQIVEEFGKAELEET
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
RVNNITKDFLPEDMREKVFALKVGEVSEVLASSFGWHIIKVESAHQISDEDLVDLKKDIK
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHH
SVLTNQKSFERVNDFINQVNYKIYNGSAIEEILSEYNLPIQTIGPVDASGKDQSGNNVGD
HHHCCHHHHHHHHHHHHHCCCEEECCHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCC
SSDLISFIFSREKDQKGYFKGVGDAVVSVKIIDIVPPKSQSFEEGRASAVELWQSEFIKE
HHHHHHHHHHCCCCCCCHHHCCCCHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
RMFKIGQEFAVQLREKTDWEKIQGVELVEDQQMHRNEQNYPFSFVEEIFNMKTTGSVTDP
HHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCC
IQYNNEIIIGVLKEMHSSNGKLNMLDTGKRVMISLKEQLISYLESKYKVEVNHAILDDI
CCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHEEEEHHHHHCCC
>Mature Secondary Structure
MNVKNFFTKVTVVLLACLLIFVGVGNLLSGDDEKEEVARVGKEVITSDEYKSLYQNYGKQ
CCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCC
ISGSDASREQVKKLKYDLLNALIEQKLLFNLTSELGLTVGEESIKNHIKNTKYFQNDKGE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCC
FDKNKFHETLNDLHMTEKEYIAKLEKILPAMMFMTSLFKDNYPVTFGEKIDEQIYNSRYQ
CCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHH
TRVVDIVKITEDAVTNIPEPDDQTLLDLYERNKSHFYYPEYRTAQYISLEQKYFEDQIKI
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHCC
SDEEVDGIIEQQELRDQRDIFNIIFSTKEEAETARRAFEEGKTSFEQIVEEFGKAELEET
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
RVNNITKDFLPEDMREKVFALKVGEVSEVLASSFGWHIIKVESAHQISDEDLVDLKKDIK
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHH
SVLTNQKSFERVNDFINQVNYKIYNGSAIEEILSEYNLPIQTIGPVDASGKDQSGNNVGD
HHHCCHHHHHHHHHHHHHCCCEEECCHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCC
SSDLISFIFSREKDQKGYFKGVGDAVVSVKIIDIVPPKSQSFEEGRASAVELWQSEFIKE
HHHHHHHHHHCCCCCCCHHHCCCCHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
RMFKIGQEFAVQLREKTDWEKIQGVELVEDQQMHRNEQNYPFSFVEEIFNMKTTGSVTDP
HHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCC
IQYNNEIIIGVLKEMHSSNGKLNMLDTGKRVMISLKEQLISYLESKYKVEVNHAILDDI
CCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHEEEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]