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The map label for this gene is glpX [H]

Identifier: 225630307

GI number: 225630307

Start: 558033

End: 558971

Strand: Reverse

Name: glpX [H]

Synonym: WRi_005270

Alternate gene names: 225630307

Gene position: 558971-558033 (Counterclockwise)

Preceding gene: 225630309

Following gene: 225630306

Centisome position: 38.66

GC content: 38.87

Gene sequence:

>939_bases
ATGCTTTATTTATGGTTCTTAAAGCAAATGATGGAAGATTTAGCCTATAAATTAGTTAAAGTGACCGAAGCTGCAGCACT
TGCTGCATATAAACTAGCAGGCTTCGGCGATGAAAAAAAGGCTGATCAGGTTGCAGTTGATGCAATGCGTACAGTATTAA
ATTCAATGGAAATAAATGGTACTATCGTAATTGGTGAAGGTGAGAGAGATGAAGCGCCGATGCTATATATTGGCGAGAAG
GTTGGCACTGGAAATGGTCCTGAGATTGACATTGCTGTTGACCCACTTGAAGGCACTACGATTTGTGCTCATTACAAATC
AGGGGCAATGTCCGTTCTTGCTGCAACGAAAAAAGGTAATTTTTTACATGCACCTGATGTTTATATGGAAAAGATAGCAG
TAGGAAAAAATCTTCCAGAGGGTGTAGTCTCACTAAAAAATAGCATTGAAAAGAATCTAGACAATTTAGCCAAGGCAAAA
AAATGCAAAGTGAATGATCTCGTGGTAACTGTACTTAAACGTGAAAGGCATGGTGAATTAATAGAGAAAATCAGGAAATT
AGGAGCAAAAATTAAACTAATAGATGATGGTGATGTTGCGGCCATAGTTTCACTAGTAAATGGCAATCATGATATGTATA
TCGGTATAGGAGGAGCACCAGAGGGAGTGCTTGCGGCTGCAGCGCTAAGCTCTATCGGCGGACAGATGGAGGGAAGATTA
GTACTTGACACGGATCAGTTAAGAGAAAGAGCAAAAAATTTAAATATTGATGACCCAGAAAAAGTCTACGCCGTAAAAGA
TATGGCAAGAGGTGAATCAGTGTTCATTGCAACTGGAGTAACAAGCGGAGAACTTGTGGATGGAGTTGATAACATATGTT
CAACTAGTTCTTTAATAATTCTACCTAACAAGCTGATAAAGCTGCAAGTTATAAATTAG

Upstream 100 bases:

>100_bases
CATGTCAAATTTTACCACTATTACTATCTAATTTATTATAGCAACTTTCCCATAACCAGTCAAGACATATTGCAGTTTCA
AGCAGCATGATATATATTCA

Downstream 100 bases:

>100_bases
GTTAATTATTTTTCAATACACCTAAACTTTAGCTTTACAATACTGATATTAGAATATACTATTTATATTGTTTCTATCTT
AAGAAAAAGGAGGTCCTGGA

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MLYLWFLKQMMEDLAYKLVKVTEAAALAAYKLAGFGDEKKADQVAVDAMRTVLNSMEINGTIVIGEGERDEAPMLYIGEK
VGTGNGPEIDIAVDPLEGTTICAHYKSGAMSVLAATKKGNFLHAPDVYMEKIAVGKNLPEGVVSLKNSIEKNLDNLAKAK
KCKVNDLVVTVLKRERHGELIEKIRKLGAKIKLIDDGDVAAIVSLVNGNHDMYIGIGGAPEGVLAAAALSSIGGQMEGRL
VLDTDQLRERAKNLNIDDPEKVYAVKDMARGESVFIATGVTSGELVDGVDNICSTSSLIILPNKLIKLQVIN

Sequences:

>Translated_312_residues
MLYLWFLKQMMEDLAYKLVKVTEAAALAAYKLAGFGDEKKADQVAVDAMRTVLNSMEINGTIVIGEGERDEAPMLYIGEK
VGTGNGPEIDIAVDPLEGTTICAHYKSGAMSVLAATKKGNFLHAPDVYMEKIAVGKNLPEGVVSLKNSIEKNLDNLAKAK
KCKVNDLVVTVLKRERHGELIEKIRKLGAKIKLIDDGDVAAIVSLVNGNHDMYIGIGGAPEGVLAAAALSSIGGQMEGRL
VLDTDQLRERAKNLNIDDPEKVYAVKDMARGESVFIATGVTSGELVDGVDNICSTSSLIILPNKLIKLQVIN
>Mature_312_residues
MLYLWFLKQMMEDLAYKLVKVTEAAALAAYKLAGFGDEKKADQVAVDAMRTVLNSMEINGTIVIGEGERDEAPMLYIGEK
VGTGNGPEIDIAVDPLEGTTICAHYKSGAMSVLAATKKGNFLHAPDVYMEKIAVGKNLPEGVVSLKNSIEKNLDNLAKAK
KCKVNDLVVTVLKRERHGELIEKIRKLGAKIKLIDDGDVAAIVSLVNGNHDMYIGIGGAPEGVLAAAALSSIGGQMEGRL
VLDTDQLRERAKNLNIDDPEKVYAVKDMARGESVFIATGVTSGELVDGVDNICSTSSLIILPNKLIKLQVIN

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=309, Percent_Identity=45.6310679611651, Blast_Score=240, Evalue=7e-65,
Organism=Escherichia coli, GI1789298, Length=309, Percent_Identity=42.0711974110032, Blast_Score=222, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 33494; Mature: 33494

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYLWFLKQMMEDLAYKLVKVTEAAALAAYKLAGFGDEKKADQVAVDAMRTVLNSMEING
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCE
TIVIGEGERDEAPMLYIGEKVGTGNGPEIDIAVDPLEGTTICAHYKSGAMSVLAATKKGN
EEEEECCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCEEEEEECCCCEEEEEEECCCC
FLHAPDVYMEKIAVGKNLPEGVVSLKNSIEKNLDNLAKAKKCKVNDLVVTVLKRERHGEL
EEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IEKIRKLGAKIKLIDDGDVAAIVSLVNGNHDMYIGIGGAPEGVLAAAALSSIGGQMEGRL
HHHHHHCCCEEEEEECCCCEEHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEE
VLDTDQLRERAKNLNIDDPEKVYAVKDMARGESVFIATGVTSGELVDGVDNICSTSSLII
EECHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEE
LPNKLIKLQVIN
ECCCEEEEEEEC
>Mature Secondary Structure
MLYLWFLKQMMEDLAYKLVKVTEAAALAAYKLAGFGDEKKADQVAVDAMRTVLNSMEING
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCE
TIVIGEGERDEAPMLYIGEKVGTGNGPEIDIAVDPLEGTTICAHYKSGAMSVLAATKKGN
EEEEECCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCEEEEEECCCCEEEEEEECCCC
FLHAPDVYMEKIAVGKNLPEGVVSLKNSIEKNLDNLAKAKKCKVNDLVVTVLKRERHGEL
EEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IEKIRKLGAKIKLIDDGDVAAIVSLVNGNHDMYIGIGGAPEGVLAAAALSSIGGQMEGRL
HHHHHHCCCEEEEEECCCCEEHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEE
VLDTDQLRERAKNLNIDDPEKVYAVKDMARGESVFIATGVTSGELVDGVDNICSTSSLII
EECHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEE
LPNKLIKLQVIN
ECCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]