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The map label for this gene is murB [H]

Identifier: 225630164

GI number: 225630164

Start: 379159

End: 380046

Strand: Reverse

Name: murB [H]

Synonym: WRi_003550

Alternate gene names: 225630164

Gene position: 380046-379159 (Counterclockwise)

Preceding gene: 225630165

Following gene: 225630157

Centisome position: 26.28

GC content: 38.18

Gene sequence:

>888_bases
ATGCTTATAAGCTTACCTAAAGTACGTGGAATCTATCGTTATGACATCTTAATGTCTAAAGCAACGTGGTTAAATGTCGG
TGGACGAGCTGATATATTATTTAAACCACGTGATATTGAAGATTTAACATGCTTGATTAAAAACACTGAGTTGCCAGTTA
GCGTTATTGGTGCAACATCCAACATAATAGTGCGAGATAGTGGCATTCGAGGAATAACAGTAAAATTAGGTAAGGAGTTT
GCATATATTAAAAGTAAGGGTAACAACTCTATTGTAGCTGGGGGAGCTGTGCTGCTCAGCAACCTTGCTCACTTTGCGGG
AAATCAGCAGATTAGTGGGTTGGAGTTTCTAGTTGGAATTCCAGGAACAGTTGGTGGCGGAATAGAAATGAATGCAGGTG
CATATGGTAGTGATATCGCAAGTGTTGTACAATCCATAAAAGCAGTGAATCTAGAGGATGGAAACCTATATGAGTTCTCC
AGCGAAGAAATGGGGTATTTTTACCGTGGACATAGCCTAAAAGGAAATTGGATTTTTGTTGAAGCTGAGTTTAAAGGAGT
AAACTCAGAGTATGAGCTTATACTGCAAAGGTTAAAGGAAGTTATTGAGAGGAAAAATAAAAGCCAGCCAATAAGAGGAA
AAACTGCTGGGTGCATATTCAAAAATCCAAAAAACTACCGAGCATGGGAGTTAATTGATAAATCTGGCTGCCTAGGGTTA
AATATTGGTGGAGCTAGAATCTCTAAGAAACATTGTAACTTCTTGCTCAATTACGATAATGCAACTGCATCTGACTTGGA
AAACCTTGGCAACAAAGTAAAAGATGCAGTAAAGGATAAATTTAATGTTGAACTTGAGTGGGAAATAAGGGTTTTGGGTA
GCTATTAG

Upstream 100 bases:

>100_bases
TGTTGGCAGATGGAAAAAATATATACTTCACTGAGCGCACTTCATTTATAGAAGATGCGGAGAAAATGGGTATGGATGCA
GGGTTAGAGTTGAAATCAAA

Downstream 100 bases:

>100_bases
ATAGTTTTTATAGCTTATGTATATTCGTTCAGGAGAACGGCAAATAAGGTAAACAAGTAATCTAAAAAAATAATCATAGA
GAAACCGTGAGGTAATGTGG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MLISLPKVRGIYRYDILMSKATWLNVGGRADILFKPRDIEDLTCLIKNTELPVSVIGATSNIIVRDSGIRGITVKLGKEF
AYIKSKGNNSIVAGGAVLLSNLAHFAGNQQISGLEFLVGIPGTVGGGIEMNAGAYGSDIASVVQSIKAVNLEDGNLYEFS
SEEMGYFYRGHSLKGNWIFVEAEFKGVNSEYELILQRLKEVIERKNKSQPIRGKTAGCIFKNPKNYRAWELIDKSGCLGL
NIGGARISKKHCNFLLNYDNATASDLENLGNKVKDAVKDKFNVELEWEIRVLGSY

Sequences:

>Translated_295_residues
MLISLPKVRGIYRYDILMSKATWLNVGGRADILFKPRDIEDLTCLIKNTELPVSVIGATSNIIVRDSGIRGITVKLGKEF
AYIKSKGNNSIVAGGAVLLSNLAHFAGNQQISGLEFLVGIPGTVGGGIEMNAGAYGSDIASVVQSIKAVNLEDGNLYEFS
SEEMGYFYRGHSLKGNWIFVEAEFKGVNSEYELILQRLKEVIERKNKSQPIRGKTAGCIFKNPKNYRAWELIDKSGCLGL
NIGGARISKKHCNFLLNYDNATASDLENLGNKVKDAVKDKFNVELEWEIRVLGSY
>Mature_295_residues
MLISLPKVRGIYRYDILMSKATWLNVGGRADILFKPRDIEDLTCLIKNTELPVSVIGATSNIIVRDSGIRGITVKLGKEF
AYIKSKGNNSIVAGGAVLLSNLAHFAGNQQISGLEFLVGIPGTVGGGIEMNAGAYGSDIASVVQSIKAVNLEDGNLYEFS
SEEMGYFYRGHSLKGNWIFVEAEFKGVNSEYELILQRLKEVIERKNKSQPIRGKTAGCIFKNPKNYRAWELIDKSGCLGL
NIGGARISKKHCNFLLNYDNATASDLENLGNKVKDAVKDKFNVELEWEIRVLGSY

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 32463; Mature: 32463

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLISLPKVRGIYRYDILMSKATWLNVGGRADILFKPRDIEDLTCLIKNTELPVSVIGATS
CEECCCCCCCEEEEEEEEECCEEEECCCCEEEEECCCCCCCEEEEEECCCCCEEEEECCC
NIIVRDSGIRGITVKLGKEFAYIKSKGNNSIVAGGAVLLSNLAHFAGNQQISGLEFLVGI
EEEEEECCCCEEEEEECCEEEEEEECCCCEEEECHHHHHHHHHHHCCCCCCCCEEEEEEC
PGTVGGGIEMNAGAYGSDIASVVQSIKAVNLEDGNLYEFSSEEMGYFYRGHSLKGNWIFV
CCCCCCCEEECCCCCCHHHHHHHHHHHEECCCCCCEEEECCCCCCEEEECCCCCCCEEEE
EAEFKGVNSEYELILQRLKEVIERKNKSQPIRGKTAGCIFKNPKNYRAWELIDKSGCLGL
EEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCEEEE
NIGGARISKKHCNFLLNYDNATASDLENLGNKVKDAVKDKFNVELEWEIRVLGSY
ECCCCEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECC
>Mature Secondary Structure
MLISLPKVRGIYRYDILMSKATWLNVGGRADILFKPRDIEDLTCLIKNTELPVSVIGATS
CEECCCCCCCEEEEEEEEECCEEEECCCCEEEEECCCCCCCEEEEEECCCCCEEEEECCC
NIIVRDSGIRGITVKLGKEFAYIKSKGNNSIVAGGAVLLSNLAHFAGNQQISGLEFLVGI
EEEEEECCCCEEEEEECCEEEEEEECCCCEEEECHHHHHHHHHHHCCCCCCCCEEEEEEC
PGTVGGGIEMNAGAYGSDIASVVQSIKAVNLEDGNLYEFSSEEMGYFYRGHSLKGNWIFV
CCCCCCCEEECCCCCCHHHHHHHHHHHEECCCCCCEEEECCCCCCEEEECCCCCCCEEEE
EAEFKGVNSEYELILQRLKEVIERKNKSQPIRGKTAGCIFKNPKNYRAWELIDKSGCLGL
EEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCEEEE
NIGGARISKKHCNFLLNYDNATASDLENLGNKVKDAVKDKFNVELEWEIRVLGSY
ECCCCEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA