Click here to switch to the map view.

The map label for this gene is ctaA [H]

Identifier: 225630130

GI number: 225630130

Start: 336343

End: 337371

Strand: Reverse

Name: ctaA [H]

Synonym: WRi_003120

Alternate gene names: 225630130

Gene position: 337371-336343 (Counterclockwise)

Preceding gene: 225630131

Following gene: 225630127

Centisome position: 23.33

GC content: 35.47

Gene sequence:

>1029_bases
ATGGAAGCAAAACCTGTAGCTATTTGGCTTTTTCTCTGCTCGGTCATGGTAATTCTCATGGTAGGAATTGGTGGATTTAC
CAGACTTTCAAAAGCAGGATTGTCAATCACGGAGTGGAAACCAATTACTGGAACATTACCACCACTGAGTGAACAAGACT
GGCTACAAGAAAAATTAAAATACGAAGCTACACCTGAATATAAAGCACTTAACTATGGTATTAGTATGGAGGAGTTTCGC
GCTATATACTTAATAGAATATATACACAGATTGGTTGCAAGACTAACAGGTTTAGTTTTTGTCCTGCCATTTATATATTT
CATATTAAGAAGAAAAATATCTAAAAAGGTAGTAATAAAGCTATTTGTGGCATTATTATTTGGAGCTTTACAAGCTTTTG
CTGGTTGGTATATGGTAAAAAGCGGCTTGGTAGCCAAGCCTCATGTTAGCCACTATAGGCTCGCACTTCACTTATTATTA
GCATTAGTTATCTTTGCATTATTGTCATATCAATTTTTTGATTATCAGATAAGGCCACAACAAACAAAACTTAAGGTTAG
TGGTAACACTATATACTACGCAAGGATGATTTTGGTCCTAATTGTAATACAAATAATTTTCGGCGCATTTGTTGCGGGAT
TAAATGCTGGTTTGATTTACAATACCTTTCCACTAATGGACGGACAAATCGTTCCAGAAGATTTATTTTTCTTACAGCCT
ATATGGCTGAATATCTTTGAGAACAGAGCGACAGTGCAATTTATACATCGAGCACTGGCATTGCTAATACTAACTTTGGT
AGTAATACTCACAGTAAAAAATGCTAGCATAAAACCGGTATATATTATGCTGCTCTCCGTCGTCATTCAGATCATTTTAG
GTGTAATTACTCTATTATTGCACATACCGATAGCCATTGCCATAGCTCATCAAGTGTTTTCATTTATCTTGTTTGGGTCA
AGTTTATACTTCTTGTGTTATTTAAGGAAGCAGACTACATCACCAATCTGCACATTTTTTCCTTCTTGA

Upstream 100 bases:

>100_bases
TTTTTCCGGTCTATAGTCTGCTACATAGTGTTGCAGCTTTTCTTGCCTTATGGGAATTTATTCTTTACCCTGAGCGATGG
AACAAAACTCAGCATGGTTT

Downstream 100 bases:

>100_bases
ACGGGAATATTTTTTATCACCATTGCTGCTTCAGCACATATGATATTTTCCATTTTCATTGCCTCCACCACAAATAAAGG
TTGTCCTATTTCCACCTGAT

Product: cytochrome c oxidase assembly protein

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MEAKPVAIWLFLCSVMVILMVGIGGFTRLSKAGLSITEWKPITGTLPPLSEQDWLQEKLKYEATPEYKALNYGISMEEFR
AIYLIEYIHRLVARLTGLVFVLPFIYFILRRKISKKVVIKLFVALLFGALQAFAGWYMVKSGLVAKPHVSHYRLALHLLL
ALVIFALLSYQFFDYQIRPQQTKLKVSGNTIYYARMILVLIVIQIIFGAFVAGLNAGLIYNTFPLMDGQIVPEDLFFLQP
IWLNIFENRATVQFIHRALALLILTLVVILTVKNASIKPVYIMLLSVVIQIILGVITLLLHIPIAIAIAHQVFSFILFGS
SLYFLCYLRKQTTSPICTFFPS

Sequences:

>Translated_342_residues
MEAKPVAIWLFLCSVMVILMVGIGGFTRLSKAGLSITEWKPITGTLPPLSEQDWLQEKLKYEATPEYKALNYGISMEEFR
AIYLIEYIHRLVARLTGLVFVLPFIYFILRRKISKKVVIKLFVALLFGALQAFAGWYMVKSGLVAKPHVSHYRLALHLLL
ALVIFALLSYQFFDYQIRPQQTKLKVSGNTIYYARMILVLIVIQIIFGAFVAGLNAGLIYNTFPLMDGQIVPEDLFFLQP
IWLNIFENRATVQFIHRALALLILTLVVILTVKNASIKPVYIMLLSVVIQIILGVITLLLHIPIAIAIAHQVFSFILFGS
SLYFLCYLRKQTTSPICTFFPS
>Mature_342_residues
MEAKPVAIWLFLCSVMVILMVGIGGFTRLSKAGLSITEWKPITGTLPPLSEQDWLQEKLKYEATPEYKALNYGISMEEFR
AIYLIEYIHRLVARLTGLVFVLPFIYFILRRKISKKVVIKLFVALLFGALQAFAGWYMVKSGLVAKPHVSHYRLALHLLL
ALVIFALLSYQFFDYQIRPQQTKLKVSGNTIYYARMILVLIVIQIIFGAFVAGLNAGLIYNTFPLMDGQIVPEDLFFLQP
IWLNIFENRATVQFIHRALALLILTLVVILTVKNASIKPVYIMLLSVVIQIILGVITLLLHIPIAIAIAHQVFSFILFGS
SLYFLCYLRKQTTSPICTFFPS

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group [H]

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921985, Length=341, Percent_Identity=36.950146627566, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI17921987, Length=274, Percent_Identity=39.051094890511, Blast_Score=192, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17536069, Length=347, Percent_Identity=34.2939481268012, Blast_Score=205, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6320989, Length=369, Percent_Identity=36.0433604336043, Blast_Score=211, Evalue=2e-55,
Organism=Drosophila melanogaster, GI19922860, Length=350, Percent_Identity=38.2857142857143, Blast_Score=210, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003780 [H]

Pfam domain/function: PF02628 COX15-CtaA [H]

EC number: NA

Molecular weight: Translated: 38871; Mature: 38871

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAKPVAIWLFLCSVMVILMVGIGGFTRLSKAGLSITEWKPITGTLPPLSEQDWLQEKLK
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHHHC
YEATPEYKALNYGISMEEFRAIYLIEYIHRLVARLTGLVFVLPFIYFILRRKISKKVVIK
CCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVALLFGALQAFAGWYMVKSGLVAKPHVSHYRLALHLLLALVIFALLSYQFFDYQIRPQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCC
QTKLKVSGNTIYYARMILVLIVIQIIFGAFVAGLNAGLIYNTFPLMDGQIVPEDLFFLQP
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCCCCCCCHHHHHHHH
IWLNIFENRATVQFIHRALALLILTLVVILTVKNASIKPVYIMLLSVVIQIILGVITLLL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HIPIAIAIAHQVFSFILFGSSLYFLCYLRKQTTSPICTFFPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCC
>Mature Secondary Structure
MEAKPVAIWLFLCSVMVILMVGIGGFTRLSKAGLSITEWKPITGTLPPLSEQDWLQEKLK
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHHHC
YEATPEYKALNYGISMEEFRAIYLIEYIHRLVARLTGLVFVLPFIYFILRRKISKKVVIK
CCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVALLFGALQAFAGWYMVKSGLVAKPHVSHYRLALHLLLALVIFALLSYQFFDYQIRPQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCC
QTKLKVSGNTIYYARMILVLIVIQIIFGAFVAGLNAGLIYNTFPLMDGQIVPEDLFFLQP
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCCCCCCCHHHHHHHH
IWLNIFENRATVQFIHRALALLILTLVVILTVKNASIKPVYIMLLSVVIQIILGVITLLL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HIPIAIAIAHQVFSFILFGSSLYFLCYLRKQTTSPICTFFPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA