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The map label for this gene is coaE

Identifier: 225630013

GI number: 225630013

Start: 173863

End: 174450

Strand: Reverse

Name: coaE

Synonym: WRi_001750

Alternate gene names: 225630013

Gene position: 174450-173863 (Counterclockwise)

Preceding gene: 225630014

Following gene: 225630012

Centisome position: 12.07

GC content: 33.16

Gene sequence:

>588_bases
ATGATTATAAGTCTAACAGGCGGAATTGGGGTAGGAAAGAGCTTTGTAGCTAATTGCTTTCAAGAGTTTGGTGCTGTTGT
ATTTGATGCTGATTCTGTTGTACACCAACTTTATAAAGTGGATAAAAGCATAATAAGTTATGCAGAGAAAAATTTTCCTG
GAGTGGTAGTAAATGGTGAAATAGATAGAACAGTACTGTCTAAATATTTCTTAGCCTACGATGAAAATTGGAAACAATTT
CAATCTTTGGTTCACTCTGCTGTGCTGCGTGAATTAGAATTTTTTATTGCCAAGGAAAAAAAGATCGATAGAAAACTTTT
AGTTTTAGATGTGCCACTTCTATTAGAAACAAAATTTTATTTATATTGCGACCTTATTGTTTTTGTTCATGCAGATAGCG
TTGTGCAAGCTCAAAGACTTAACGAACGCAACATAGATAAAGAAAAGCTTAATCTAATCTCCGATGTTCAGTTATCTATT
GAGGAGAAAAGGAAGATGAGTGACTTTATTATCGATACCAGTGTAAGCAAAGAGTATGTTTTTTCTCAAGTAAAAGATAT
AGTGGATTCATTAAACCTAAACACGTAG

Upstream 100 bases:

>100_bases
GTATAGTTATGTGCTTGACACTGGGATCTAGAAAATCTAGTTAATATATATAGAGAAACCTTAGCTATAGTTTCAAAAGA
AGTCGAATGTATTTTGTTAT

Downstream 100 bases:

>100_bases
CTCTACGTCATACCGCCGCGGTATCTCTAGATCCCGCTAACAAGCAGCGGGATGACGGTTGTCAGGATCCCAGCAGCCTC
CCTCCCCTATCATCCAAGTA

Product: dephospho-coa kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MIISLTGGIGVGKSFVANCFQEFGAVVFDADSVVHQLYKVDKSIISYAEKNFPGVVVNGEIDRTVLSKYFLAYDENWKQF
QSLVHSAVLRELEFFIAKEKKIDRKLLVLDVPLLLETKFYLYCDLIVFVHADSVVQAQRLNERNIDKEKLNLISDVQLSI
EEKRKMSDFIIDTSVSKEYVFSQVKDIVDSLNLNT

Sequences:

>Translated_195_residues
MIISLTGGIGVGKSFVANCFQEFGAVVFDADSVVHQLYKVDKSIISYAEKNFPGVVVNGEIDRTVLSKYFLAYDENWKQF
QSLVHSAVLRELEFFIAKEKKIDRKLLVLDVPLLLETKFYLYCDLIVFVHADSVVQAQRLNERNIDKEKLNLISDVQLSI
EEKRKMSDFIIDTSVSKEYVFSQVKDIVDSLNLNT
>Mature_195_residues
MIISLTGGIGVGKSFVANCFQEFGAVVFDADSVVHQLYKVDKSIISYAEKNFPGVVVNGEIDRTVLSKYFLAYDENWKQF
QSLVHSAVLRELEFFIAKEKKIDRKLLVLDVPLLLETKFYLYCDLIVFVHADSVVQAQRLNERNIDKEKLNLISDVQLSI
EEKRKMSDFIIDTSVSKEYVFSQVKDIVDSLNLNT

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Homo sapiens, GI191252797, Length=184, Percent_Identity=28.2608695652174, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI191252795, Length=184, Percent_Identity=28.2608695652174, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1786292, Length=186, Percent_Identity=26.3440860215054, Blast_Score=67, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17554944, Length=197, Percent_Identity=25.3807106598985, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320402, Length=204, Percent_Identity=25.9803921568627, Blast_Score=76, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644728, Length=190, Percent_Identity=28.9473684210526, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_WOLPM (Q73IH9)

Other databases:

- EMBL:   AE017196
- RefSeq:   NP_965999.1
- ProteinModelPortal:   Q73IH9
- SMR:   Q73IH9
- EnsemblBacteria:   EBWOLT00000004232
- GeneID:   2738643
- GenomeReviews:   AE017196_GR
- KEGG:   wol:WD0185
- TIGR:   WD_0185
- GeneTree:   EBGT00050000031431
- HOGENOM:   HBG650290
- OMA:   HEFELIS
- ProtClustDB:   CLSK739879
- BioCyc:   WPIP955:WD_0185-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 22298; Mature: 22298

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS51219 DPCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIISLTGGIGVGKSFVANCFQEFGAVVFDADSVVHQLYKVDKSIISYAEKNFPGVVVNGE
CEEEEECCCCCCHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
IDRTVLSKYFLAYDENWKQFQSLVHSAVLRELEFFIAKEKKIDRKLLVLDVPLLLETKFY
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHH
LYCDLIVFVHADSVVQAQRLNERNIDKEKLNLISDVQLSIEEKRKMSDFIIDTSVSKEYV
HHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FSQVKDIVDSLNLNT
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MIISLTGGIGVGKSFVANCFQEFGAVVFDADSVVHQLYKVDKSIISYAEKNFPGVVVNGE
CEEEEECCCCCCHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
IDRTVLSKYFLAYDENWKQFQSLVHSAVLRELEFFIAKEKKIDRKLLVLDVPLLLETKFY
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHH
LYCDLIVFVHADSVVQAQRLNERNIDKEKLNLISDVQLSIEEKRKMSDFIIDTSVSKEYV
HHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FSQVKDIVDSLNLNT
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA