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The map label for this gene is ftsK [H]

Identifier: 225629980

GI number: 225629980

Start: 128283

End: 130397

Strand: Direct

Name: ftsK [H]

Synonym: WRi_001290

Alternate gene names: 225629980

Gene position: 128283-130397 (Clockwise)

Preceding gene: 225629979

Following gene: 225629981

Centisome position: 8.87

GC content: 37.54

Gene sequence:

>2115_bases
ATGCTAAAAAGATATCTAAAAGCAGCAGTATATCTATCACTCTTAATATATATATATATATCAGTTTTTAGCTACAACTA
TAAAGATCCTTCCTTAAACACAGCTACAAATGAGAAAGTGACAAATTTAGGTGGAATAGTAAGTTCATATTTAGCTGATA
TATTGGTTCAATTTCTTGGATTAACTAGTGTTACAATAGCTACAACCATAGTTTACTTGTTGATCTTCAGGCCATCAAAA
AGGCTGCTAAAAATTCTCTATTTAATATTAATCAATTTAGGGATATGTGCTATACTACCACAACTTTCGCTAGGCATCAC
TGCAAGGTACAGACACAGTGGAATAATAGGGAATGCACTAATTAATAACTGCCCGTTTTATATATTTGTGATAGTAACAT
CAATAGGTCTTGTAGGATCTGTTGGTTGGAAGAGAACAATTTACTCTCTATTCTTCTTATGTAAAAAAATAGCTTGCTTA
TTTGTAAATGTTCCATTCTTCAGATCACATAAAACTACTGAGTATTCAATTGCACCATTAGTAGTAGAAGAAAAACATAG
AACTAAAATCACTACTAAACAACAACCAAAAGAAAGACAGAAAAAAGCTACCGAGGAGGTTTTAAGTGAGTTTAAGTTTC
CAAGTATCCATTTACTTTCTAAAGCAGAGGAGTCTTTGCAGAGAAAGCAGCTGAATGAAATGGAGAGCAATAAAAATTTA
TCTCTGCTGGAACAAGTCCTGAGTGATTTTGGCGTGCAAGGAAAAATTATCAGTGTATGCTATGGGCCGGTTGTGACTTT
GTACAAACTTGAACCACAAGCTGGCACGAAATCTGCAAGAGTAATTGGCCTTGCAGATGACATTGCACGTTCGATGAGTG
CACTCTCTGCACGTATTTCAATAATTCGTGGGCAAAATGCTATGGGAATAGAGTTGCCGAACAAGGAACGGGAAATTGTA
ATGCTGCGTGATTTGCTTGAATCCCCAGAATACCAAAATGCAAACTTAAATCTCCCAATTGCGCTTGGCAAAGAAATAAG
TGGAAAACCAGTTATTGCAGATCTAACTAAAATGCCCCACTTGCTCGTTGCTGGAACCACAGGGTCAGGTAAATCAGTTG
CGATTAACACTATGATTCTTTCACTCGTTTATCGATTAAGTCCTGATGAATGTAAGATGATAATGATCGACCCAAAAATG
CTTGAGCTTTCAATATATGATGCAATACCGCATCTAATAACGCCAGTGGTAACAGAGCCAAAAAAGGCTGTAGTCGCTCT
TAAGTGGATAGTGAAAGAGATGGAAAATCGCTATCGCATGATGTCGTATTTGAATGTACGCAATGTAATAAACTATAACC
AAAGAATCACAGAAGCGATGAATAGTGGAATAGAATTGAAGCGCGTTGTGCAGATTGGCTTTAACTCAACAACAGGCAAA
CCTTTGTTTGAAAAGCTGCCGATTAAAATGGAAACATTCCCATATATTGTAGTGATTGTAGATGAAATGGCAGATTTGAT
GCTTGTTGCCGGCAAAGAAATAGAGTGCTCTATTCAACGCTTAGCTCAGATGGCTCGTGCTGCAGGAATACACATCATAA
TGGCAACACAACGCCCATCTGTGGATGTGATCACAGGTGTGATAAAGGCGAACTTTCCAACGAGAATCAGTTTTGCTGTT
ACTTCTAAGATAGATAGTCGCACAATACTTGGCGAACAAGGGGCTGAACAATTGCTTGGTATGGGTGATATGCTTTATAT
GGCCTCTGGTGGTAAGATTATTCGAATTCACGGCCCATTTGTGAGCGATGATGAGGTACAAGATATAGTTGATCATCTGA
AAATGCAAGGTGAGCCAAATTATATGGAGGAAATTACCAAAGAAGATGAAAATTCTTCTGTGGAATCAGAAGGTGAAACA
GAGGATGAAGAAAACGACCTCTACAATCAAGCAGTGGCCATCATTCAAAGAGATCAAAAAGTTTCAACCAGTTACATTCA
GCGACAACTTAGAATAGGCTATAACAGAGCTGCAAATATTGTTGAAAGAATGGAAAAAGAAGGTGTTGTCAGCGCTCCAA
ATTACTCAGGGAAGAGAGAGATATTAGTAGAATAA

Upstream 100 bases:

>100_bases
AGATACATACCACCGTTCAACGGATTAGATTTATCTATAATGATATTGCTAATAGCAATTCGCTTTGTACAATATACAAT
GAATTACTACTTTTAAGTAG

Downstream 100 bases:

>100_bases
CAGGGCTTCTGAGAACGTTCATGTGCGTTAAGTTAGGCCATAGATGGGTATCTTAAAATTTGCTGCAAATGCAACTTTCT
TGGCTATCTTTTACAAAGTT

Product: cell division protein FtsK, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 704; Mature: 704

Protein sequence:

>704_residues
MLKRYLKAAVYLSLLIYIYISVFSYNYKDPSLNTATNEKVTNLGGIVSSYLADILVQFLGLTSVTIATTIVYLLIFRPSK
RLLKILYLILINLGICAILPQLSLGITARYRHSGIIGNALINNCPFYIFVIVTSIGLVGSVGWKRTIYSLFFLCKKIACL
FVNVPFFRSHKTTEYSIAPLVVEEKHRTKITTKQQPKERQKKATEEVLSEFKFPSIHLLSKAEESLQRKQLNEMESNKNL
SLLEQVLSDFGVQGKIISVCYGPVVTLYKLEPQAGTKSARVIGLADDIARSMSALSARISIIRGQNAMGIELPNKEREIV
MLRDLLESPEYQNANLNLPIALGKEISGKPVIADLTKMPHLLVAGTTGSGKSVAINTMILSLVYRLSPDECKMIMIDPKM
LELSIYDAIPHLITPVVTEPKKAVVALKWIVKEMENRYRMMSYLNVRNVINYNQRITEAMNSGIELKRVVQIGFNSTTGK
PLFEKLPIKMETFPYIVVIVDEMADLMLVAGKEIECSIQRLAQMARAAGIHIIMATQRPSVDVITGVIKANFPTRISFAV
TSKIDSRTILGEQGAEQLLGMGDMLYMASGGKIIRIHGPFVSDDEVQDIVDHLKMQGEPNYMEEITKEDENSSVESEGET
EDEENDLYNQAVAIIQRDQKVSTSYIQRQLRIGYNRAANIVERMEKEGVVSAPNYSGKREILVE

Sequences:

>Translated_704_residues
MLKRYLKAAVYLSLLIYIYISVFSYNYKDPSLNTATNEKVTNLGGIVSSYLADILVQFLGLTSVTIATTIVYLLIFRPSK
RLLKILYLILINLGICAILPQLSLGITARYRHSGIIGNALINNCPFYIFVIVTSIGLVGSVGWKRTIYSLFFLCKKIACL
FVNVPFFRSHKTTEYSIAPLVVEEKHRTKITTKQQPKERQKKATEEVLSEFKFPSIHLLSKAEESLQRKQLNEMESNKNL
SLLEQVLSDFGVQGKIISVCYGPVVTLYKLEPQAGTKSARVIGLADDIARSMSALSARISIIRGQNAMGIELPNKEREIV
MLRDLLESPEYQNANLNLPIALGKEISGKPVIADLTKMPHLLVAGTTGSGKSVAINTMILSLVYRLSPDECKMIMIDPKM
LELSIYDAIPHLITPVVTEPKKAVVALKWIVKEMENRYRMMSYLNVRNVINYNQRITEAMNSGIELKRVVQIGFNSTTGK
PLFEKLPIKMETFPYIVVIVDEMADLMLVAGKEIECSIQRLAQMARAAGIHIIMATQRPSVDVITGVIKANFPTRISFAV
TSKIDSRTILGEQGAEQLLGMGDMLYMASGGKIIRIHGPFVSDDEVQDIVDHLKMQGEPNYMEEITKEDENSSVESEGET
EDEENDLYNQAVAIIQRDQKVSTSYIQRQLRIGYNRAANIVERMEKEGVVSAPNYSGKREILVE
>Mature_704_residues
MLKRYLKAAVYLSLLIYIYISVFSYNYKDPSLNTATNEKVTNLGGIVSSYLADILVQFLGLTSVTIATTIVYLLIFRPSK
RLLKILYLILINLGICAILPQLSLGITARYRHSGIIGNALINNCPFYIFVIVTSIGLVGSVGWKRTIYSLFFLCKKIACL
FVNVPFFRSHKTTEYSIAPLVVEEKHRTKITTKQQPKERQKKATEEVLSEFKFPSIHLLSKAEESLQRKQLNEMESNKNL
SLLEQVLSDFGVQGKIISVCYGPVVTLYKLEPQAGTKSARVIGLADDIARSMSALSARISIIRGQNAMGIELPNKEREIV
MLRDLLESPEYQNANLNLPIALGKEISGKPVIADLTKMPHLLVAGTTGSGKSVAINTMILSLVYRLSPDECKMIMIDPKM
LELSIYDAIPHLITPVVTEPKKAVVALKWIVKEMENRYRMMSYLNVRNVINYNQRITEAMNSGIELKRVVQIGFNSTTGK
PLFEKLPIKMETFPYIVVIVDEMADLMLVAGKEIECSIQRLAQMARAAGIHIIMATQRPSVDVITGVIKANFPTRISFAV
TSKIDSRTILGEQGAEQLLGMGDMLYMASGGKIIRIHGPFVSDDEVQDIVDHLKMQGEPNYMEEITKEDENSSVESEGET
EDEENDLYNQAVAIIQRDQKVSTSYIQRQLRIGYNRAANIVERMEKEGVVSAPNYSGKREILVE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=493, Percent_Identity=47.6673427991886, Blast_Score=461, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 78827; Mature: 78827

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRYLKAAVYLSLLIYIYISVFSYNYKDPSLNTATNEKVTNLGGIVSSYLADILVQFLG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
LTSVTIATTIVYLLIFRPSKRLLKILYLILINLGICAILPQLSLGITARYRHSGIIGNAL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHH
INNCPFYIFVIVTSIGLVGSVGWKRTIYSLFFLCKKIACLFVNVPFFRSHKTTEYSIAPL
HCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECEE
VVEEKHRTKITTKQQPKERQKKATEEVLSEFKFPSIHLLSKAEESLQRKQLNEMESNKNL
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCH
SLLEQVLSDFGVQGKIISVCYGPVVTLYKLEPQAGTKSARVIGLADDIARSMSALSARIS
HHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCCCCEEEEECHHHHHHHHHHHHHHHH
IIRGQNAMGIELPNKEREIVMLRDLLESPEYQNANLNLPIALGKEISGKPVIADLTKMPH
EEECCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCE
LLVAGTTGSGKSVAINTMILSLVYRLSPDECKMIMIDPKMLELSIYDAIPHLITPVVTEP
EEEEECCCCCCEEHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEHHHHHHHHHCCCCCCC
KKAVVALKWIVKEMENRYRMMSYLNVRNVINYNQRITEAMNSGIELKRVVQIGFNSTTGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHEEECCCCCCCC
PLFEKLPIKMETFPYIVVIVDEMADLMLVAGKEIECSIQRLAQMARAAGIHIIMATQRPS
CHHHHCCCEEECCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCC
VDVITGVIKANFPTRISFAVTSKIDSRTILGEQGAEQLLGMGDMLYMASGGKIIRIHGPF
HHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHCCCCEEEEECCCEEEEEECCC
VSDDEVQDIVDHLKMQGEPNYMEEITKEDENSSVESEGETEDEENDLYNQAVAIIQRDQK
CCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCH
VSTSYIQRQLRIGYNRAANIVERMEKEGVVSAPNYSGKREILVE
HHHHHHHHHHHHCHHHHHHHHHHHHHCCCEECCCCCCCCCEEEC
>Mature Secondary Structure
MLKRYLKAAVYLSLLIYIYISVFSYNYKDPSLNTATNEKVTNLGGIVSSYLADILVQFLG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
LTSVTIATTIVYLLIFRPSKRLLKILYLILINLGICAILPQLSLGITARYRHSGIIGNAL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHH
INNCPFYIFVIVTSIGLVGSVGWKRTIYSLFFLCKKIACLFVNVPFFRSHKTTEYSIAPL
HCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECEE
VVEEKHRTKITTKQQPKERQKKATEEVLSEFKFPSIHLLSKAEESLQRKQLNEMESNKNL
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCH
SLLEQVLSDFGVQGKIISVCYGPVVTLYKLEPQAGTKSARVIGLADDIARSMSALSARIS
HHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCCCCEEEEECHHHHHHHHHHHHHHHH
IIRGQNAMGIELPNKEREIVMLRDLLESPEYQNANLNLPIALGKEISGKPVIADLTKMPH
EEECCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCE
LLVAGTTGSGKSVAINTMILSLVYRLSPDECKMIMIDPKMLELSIYDAIPHLITPVVTEP
EEEEECCCCCCEEHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEHHHHHHHHHCCCCCCC
KKAVVALKWIVKEMENRYRMMSYLNVRNVINYNQRITEAMNSGIELKRVVQIGFNSTTGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHEEECCCCCCCC
PLFEKLPIKMETFPYIVVIVDEMADLMLVAGKEIECSIQRLAQMARAAGIHIIMATQRPS
CHHHHCCCEEECCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCC
VDVITGVIKANFPTRISFAVTSKIDSRTILGEQGAEQLLGMGDMLYMASGGKIIRIHGPF
HHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHCCCCEEEEECCCEEEEEECCC
VSDDEVQDIVDHLKMQGEPNYMEEITKEDENSSVESEGETEDEENDLYNQAVAIIQRDQK
CCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCH
VSTSYIQRQLRIGYNRAANIVERMEKEGVVSAPNYSGKREILVE
HHHHHHHHHHHHCHHHHHHHHHHHHHCCCEECCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA