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The map label for this gene is nodV [H]

Identifier: 222527035

GI number: 222527035

Start: 4748371

End: 4750488

Strand: Reverse

Name: nodV [H]

Synonym: Chy400_3814

Alternate gene names: 222527035

Gene position: 4750488-4748371 (Counterclockwise)

Preceding gene: 222527037

Following gene: 222527034

Centisome position: 90.16

GC content: 51.09

Gene sequence:

>2118_bases
ATGAATCTGCACCGGTTTCTATCAACGATCTGGCCGGCTGACCGACATCTTGAGTTGCTGTCTGGCAATGAGCGACAGCG
AGTGGCTTTTCTTTTATCCCCGATCTTTGCCGTTTTTACTATTATTACAGCCATATATAGTATCATCACACCCTGGATTT
ACAGTACACCTGCCATCCCTTTAATAGCTTCTGCGATCATGATCATCGTTTTTGCCACCGGTGCGTGGCTGGTACAACGT
GGTGCTATCTACGTCGCAAGCGGATTGGTGTGTAGTGTGATCTGGCTGATTGTTACCTTCATAGTATTTTTCACCGGCGG
TTTACAGAGTTCTGTACTTTTGAACTACGTGATTGTCATTTTATTAGCCGGGGTAGGATTTGGTTGGAGAGGCATTATTA
GTGCTGTGCTGGCAAGCGGGACAGCTATCAGTGCAATATTATTCTTGACGATCACCAATCGTCTGCCAACAACAACTCCG
CTTTTAGAGTCACCACTGGCGTATGCAGTAACGATGCTGGTTATTCTTCTGCTGGCCGGTACTATTCTGTCGGTTGCTGA
TATTCAACTGGTCACTGCAATAAAGGCGACTCGCGCGAAGAATATTGAACGTGAGCGCGCCGAGCAACAACTTCGGCAGG
CGTTGCTGGCCGCACGGGCCGGGGCCTGGGAATGGGATGCAGTTAACCGTACTATTCGCTGGTCGCCGGAAAATTATCCA
CTGCTTGGGATGAATCCAGATCAGGATAGATTGAACTTTCGCACCTGGATTGAGCGGGTGCATCCCGACGACCGGCAAGC
CTTGCAGGAAGCTATCGACCGCGCTATCCATGGTCGCCAGGAGTTTGCTGTCGAGTTTCGTGTGATCTGGCCGGATGGCT
CTATTCACTGGTTGCGGGGAATTGGTCAGCCGTTAGTGCAACCAGATGGCTCCGTTCAGGGAATGTATGGTCTTCAGATT
GACATTACTGCACAGAAAGCGATTGAAATTGAACTTGCACGCAGCGAACTCTACTACCGTACACTGGTCGAAGATTTACC
GGCGCTGGTGTGCCGGTTTCGGGCTGATGGCACATTGACATTTGTCAACGATCTGTACTGTCAGACCTTTCAACGTTCGC
GGGATGAGTTAATCGGTTTTAACTTCTATGAACTGATCCCGCCTGAACAACGTGAACGGGTAGCGGCAGATATTGCCCTG
CTTAGCCGTGAGCAACCGACGATAGAACACGAGCATGAGGTCATTCATCCAGATGGCTCGATTGGCTGGCAGCGCTGGGT
CAATCGCCTGCTCTTCGATGAGTATGGGGAACCATTTGAATATCAGGCAGTGGGGATGGACATTACTGTACGTAAGAGGG
CGGAAATCGAGCGTGAGCATCTGTTACGCGAGCTGACAGCCAGAAACAGTGAACTGGAGCAATTCACGTATACAGTGTCA
CATGATCTGAAGAGTCCGTTGATCACGATCAAAGGCTTTGCCGGATATATTGAGCGTGACCTGGCTGCCGGTCGTTTGGA
ACGAATACCGGCGGATATTCAGCGGATCAAGGTCGCTGCTGATCGGATGTATCAGTTGCTAGAAGATTTGCTCAACCTGT
CACGAGCCGGACGCCAGTTAAATCAGCCCTCGCGGATCGGATTAGGGTTACTGATTAGTGAAGCCGCAGCCGCGGTGAGT
GGTCGCTTGGCCGAACGGAATGTCTATCTCCATCTGCCGCCCAATCTGCCGGAGATTTACGGTGACCGCACACGTCTGCG
GGAAGTGTTTCAGAATTTGATCGACAACGCAGCCAAATTTATGGGTGATCAGCCGAACCCACAAATCTGGATCGAAGCAC
GTCGCGCCGATCTGCCTGGATTTGTACTAGTGAGTGTTCGTGACAATGGAATTGGAATAGAACCACGTTATCTCCAGCGG
GTGTTCGGTCTCTTTGAACGCCTGAACGCTCAGGTTGATGGTACCGGCATTGGGTTAGCCCTGGCGCGCAGGATTGTGGA
AGCACACGGTGGTAAGATATGGGTGGAATCGGAAGGTCTGGGCAAAGGAACCACCTTTTATCTGACGTTGCCGGAACCTC
CGCGCCATGAAGAGAGGGTGCAAGGTCTTATTGAGTAG

Upstream 100 bases:

>100_bases
TACAATATACATCATTTCAGGTTTTGCATTGAGGATGGTCTGGACAGGTTATAATACTTTCTATCTGGAATATCATGTAT
TTTAGGCCACTTCAAAATGT

Downstream 100 bases:

>100_bases
AATGTATCGTATCCGTCAAAGGCTATGTGAATGAGTTGCATATAACAAAGAGAGATCATCTCATGAACGTGTTCGCATGA
TAGACTTATGCTATACACAC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 705; Mature: 705

Protein sequence:

>705_residues
MNLHRFLSTIWPADRHLELLSGNERQRVAFLLSPIFAVFTIITAIYSIITPWIYSTPAIPLIASAIMIIVFATGAWLVQR
GAIYVASGLVCSVIWLIVTFIVFFTGGLQSSVLLNYVIVILLAGVGFGWRGIISAVLASGTAISAILFLTITNRLPTTTP
LLESPLAYAVTMLVILLLAGTILSVADIQLVTAIKATRAKNIERERAEQQLRQALLAARAGAWEWDAVNRTIRWSPENYP
LLGMNPDQDRLNFRTWIERVHPDDRQALQEAIDRAIHGRQEFAVEFRVIWPDGSIHWLRGIGQPLVQPDGSVQGMYGLQI
DITAQKAIEIELARSELYYRTLVEDLPALVCRFRADGTLTFVNDLYCQTFQRSRDELIGFNFYELIPPEQRERVAADIAL
LSREQPTIEHEHEVIHPDGSIGWQRWVNRLLFDEYGEPFEYQAVGMDITVRKRAEIEREHLLRELTARNSELEQFTYTVS
HDLKSPLITIKGFAGYIERDLAAGRLERIPADIQRIKVAADRMYQLLEDLLNLSRAGRQLNQPSRIGLGLLISEAAAAVS
GRLAERNVYLHLPPNLPEIYGDRTRLREVFQNLIDNAAKFMGDQPNPQIWIEARRADLPGFVLVSVRDNGIGIEPRYLQR
VFGLFERLNAQVDGTGIGLALARRIVEAHGGKIWVESEGLGKGTTFYLTLPEPPRHEERVQGLIE

Sequences:

>Translated_705_residues
MNLHRFLSTIWPADRHLELLSGNERQRVAFLLSPIFAVFTIITAIYSIITPWIYSTPAIPLIASAIMIIVFATGAWLVQR
GAIYVASGLVCSVIWLIVTFIVFFTGGLQSSVLLNYVIVILLAGVGFGWRGIISAVLASGTAISAILFLTITNRLPTTTP
LLESPLAYAVTMLVILLLAGTILSVADIQLVTAIKATRAKNIERERAEQQLRQALLAARAGAWEWDAVNRTIRWSPENYP
LLGMNPDQDRLNFRTWIERVHPDDRQALQEAIDRAIHGRQEFAVEFRVIWPDGSIHWLRGIGQPLVQPDGSVQGMYGLQI
DITAQKAIEIELARSELYYRTLVEDLPALVCRFRADGTLTFVNDLYCQTFQRSRDELIGFNFYELIPPEQRERVAADIAL
LSREQPTIEHEHEVIHPDGSIGWQRWVNRLLFDEYGEPFEYQAVGMDITVRKRAEIEREHLLRELTARNSELEQFTYTVS
HDLKSPLITIKGFAGYIERDLAAGRLERIPADIQRIKVAADRMYQLLEDLLNLSRAGRQLNQPSRIGLGLLISEAAAAVS
GRLAERNVYLHLPPNLPEIYGDRTRLREVFQNLIDNAAKFMGDQPNPQIWIEARRADLPGFVLVSVRDNGIGIEPRYLQR
VFGLFERLNAQVDGTGIGLALARRIVEAHGGKIWVESEGLGKGTTFYLTLPEPPRHEERVQGLIE
>Mature_705_residues
MNLHRFLSTIWPADRHLELLSGNERQRVAFLLSPIFAVFTIITAIYSIITPWIYSTPAIPLIASAIMIIVFATGAWLVQR
GAIYVASGLVCSVIWLIVTFIVFFTGGLQSSVLLNYVIVILLAGVGFGWRGIISAVLASGTAISAILFLTITNRLPTTTP
LLESPLAYAVTMLVILLLAGTILSVADIQLVTAIKATRAKNIERERAEQQLRQALLAARAGAWEWDAVNRTIRWSPENYP
LLGMNPDQDRLNFRTWIERVHPDDRQALQEAIDRAIHGRQEFAVEFRVIWPDGSIHWLRGIGQPLVQPDGSVQGMYGLQI
DITAQKAIEIELARSELYYRTLVEDLPALVCRFRADGTLTFVNDLYCQTFQRSRDELIGFNFYELIPPEQRERVAADIAL
LSREQPTIEHEHEVIHPDGSIGWQRWVNRLLFDEYGEPFEYQAVGMDITVRKRAEIEREHLLRELTARNSELEQFTYTVS
HDLKSPLITIKGFAGYIERDLAAGRLERIPADIQRIKVAADRMYQLLEDLLNLSRAGRQLNQPSRIGLGLLISEAAAAVS
GRLAERNVYLHLPPNLPEIYGDRTRLREVFQNLIDNAAKFMGDQPNPQIWIEARRADLPGFVLVSVRDNGIGIEPRYLQR
VFGLFERLNAQVDGTGIGLALARRIVEAHGGKIWVESEGLGKGTTFYLTLPEPPRHEERVQGLIE

Specific function: Member of the two-component regulatory system nodV/nodW probably involved in the regulation of the transcription of genes involved in the nodulation process. NodV may function as a membrane-associated protein kinase that phosphorylates nodW in response to

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=405, Percent_Identity=27.1604938271605, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=34.0807174887892, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788549, Length=374, Percent_Identity=25.9358288770053, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788393, Length=267, Percent_Identity=26.9662921348315, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1789149, Length=268, Percent_Identity=26.1194029850746, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI145693157, Length=262, Percent_Identity=25.5725190839695, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=26.431718061674, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=31.8965517241379, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788713, Length=244, Percent_Identity=22.9508196721311, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786783, Length=245, Percent_Identity=26.1224489795918, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790551, Length=223, Percent_Identity=27.8026905829596, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI87081816, Length=267, Percent_Identity=26.5917602996255, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1788381, Length=320, Percent_Identity=21.875, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=218, Percent_Identity=27.5229357798165, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1790861, Length=219, Percent_Identity=27.3972602739726, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790346, Length=221, Percent_Identity=25.7918552036199, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79513; Mature: 79513

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHRFLSTIWPADRHLELLSGNERQRVAFLLSPIFAVFTIITAIYSIITPWIYSTPAIP
CCHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHH
LIASAIMIIVFATGAWLVQRGAIYVASGLVCSVIWLIVTFIVFFTGGLQSSVLLNYVIVI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LLAGVGFGWRGIISAVLASGTAISAILFLTITNRLPTTTPLLESPLAYAVTMLVILLLAG
HHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHH
TILSVADIQLVTAIKATRAKNIERERAEQQLRQALLAARAGAWEWDAVNRTIRWSPENYP
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEECCCCCC
LLGMNPDQDRLNFRTWIERVHPDDRQALQEAIDRAIHGRQEFAVEFRVIWPDGSIHWLRG
EECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHH
IGQPLVQPDGSVQGMYGLQIDITAQKAIEIELARSELYYRTLVEDLPALVCRFRADGTLT
CCCCCCCCCCCCCEEEEEEEEEEHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
FVNDLYCQTFQRSRDELIGFNFYELIPPEQRERVAADIALLSREQPTIEHEHEVIHPDGS
HHHHHHHHHHHHCHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCC
IGWQRWVNRLLFDEYGEPFEYQAVGMDITVRKRAEIEREHLLRELTARNSELEQFTYTVS
CCHHHHHHHHHHHHCCCCCEEEEECCEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
HDLKSPLITIKGFAGYIERDLAAGRLERIPADIQRIKVAADRMYQLLEDLLNLSRAGRQL
HHCCCCEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NQPSRIGLGLLISEAAAAVSGRLAERNVYLHLPPNLPEIYGDRTRLREVFQNLIDNAAKF
CCCCHHHHHHHHHHHHHHHHCHHHHCEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHH
MGDQPNPQIWIEARRADLPGFVLVSVRDNGIGIEPRYLQRVFGLFERLNAQVDGTGIGLA
CCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
LARRIVEAHGGKIWVESEGLGKGTTFYLTLPEPPRHEERVQGLIE
HHHHHHHHCCCEEEEECCCCCCCCEEEEECCCCCCHHHHHHHCCC
>Mature Secondary Structure
MNLHRFLSTIWPADRHLELLSGNERQRVAFLLSPIFAVFTIITAIYSIITPWIYSTPAIP
CCHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHH
LIASAIMIIVFATGAWLVQRGAIYVASGLVCSVIWLIVTFIVFFTGGLQSSVLLNYVIVI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LLAGVGFGWRGIISAVLASGTAISAILFLTITNRLPTTTPLLESPLAYAVTMLVILLLAG
HHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHH
TILSVADIQLVTAIKATRAKNIERERAEQQLRQALLAARAGAWEWDAVNRTIRWSPENYP
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEECCCCCC
LLGMNPDQDRLNFRTWIERVHPDDRQALQEAIDRAIHGRQEFAVEFRVIWPDGSIHWLRG
EECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHH
IGQPLVQPDGSVQGMYGLQIDITAQKAIEIELARSELYYRTLVEDLPALVCRFRADGTLT
CCCCCCCCCCCCCEEEEEEEEEEHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
FVNDLYCQTFQRSRDELIGFNFYELIPPEQRERVAADIALLSREQPTIEHEHEVIHPDGS
HHHHHHHHHHHHCHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCC
IGWQRWVNRLLFDEYGEPFEYQAVGMDITVRKRAEIEREHLLRELTARNSELEQFTYTVS
CCHHHHHHHHHHHHCCCCCEEEEECCEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
HDLKSPLITIKGFAGYIERDLAAGRLERIPADIQRIKVAADRMYQLLEDLLNLSRAGRQL
HHCCCCEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NQPSRIGLGLLISEAAAAVSGRLAERNVYLHLPPNLPEIYGDRTRLREVFQNLIDNAAKF
CCCCHHHHHHHHHHHHHHHHCHHHHCEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHH
MGDQPNPQIWIEARRADLPGFVLVSVRDNGIGIEPRYLQRVFGLFERLNAQVDGTGIGLA
CCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
LARRIVEAHGGKIWVESEGLGKGTTFYLTLPEPPRHEERVQGLIE
HHHHHHHHCCCEEEEECCCCCCCCEEEEECCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2320582; 11157954; 12597275 [H]