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The map label for this gene is mshA [H]

Identifier: 222526927

GI number: 222526927

Start: 4621314

End: 4622435

Strand: Direct

Name: mshA [H]

Synonym: Chy400_3705

Alternate gene names: 222526927

Gene position: 4621314-4622435 (Clockwise)

Preceding gene: 222526926

Following gene: 222526928

Centisome position: 87.71

GC content: 61.85

Gene sequence:

>1122_bases
ATGCGCATCGCCCTCTACAACCTGACCACCACCACCAAAATCGGTGGGGTAGAGAGTTTTGTCTGGGACCTGGCTCGTGA
ACTGGCCCAGCGCGGTCATGCGGTTGATATTTTGGGTGGGGTCGGGAATCGACGCGAAACGGCACCGGGAGTACGTGTGC
TTACCTTCCCATTTATTTCGCGTCGCTTCTGGCAGGCGTTCCCGCTGCTGCGCCGGGCTTATGCCGAAGCAAAGCTGCTG
GAGCGGCTGACGATGGCGGTTGCCGCACTCCCCACCCTGGTGCGCGAGAAGTATCAGATTATCCATCTGCAAAAACCGTA
TGATCTGGCACCGGCGCTACTGGCACGCCGGCTTAGCGGAGCGCGCGTCATCCTTGGTTGCCACGGTGAAGACTTTTACC
GTGGCGATACCTGGCTGGCACGGCGAGTGGACGCTGCGGTCTCGTGTTCGCGTTTCAATGCGCAGACGATTGCCGGTCGC
TACGGCTTCATGCCGGAGGTGGTTTTCAACGGGATTGATACCAGTCTGTTCCGTCCACAGCCACCTGATCCAACTCTGCG
CGAACGGCTTGGCGTGTCGTCGACCGTGCCCCTGCTCCTCTTTGTTGGTCGGCTCCAACCGTGGAAAGGGGTAGAGACGG
CAATTCGGGCACTCTGTCACATCGATCAGGCAATCCTGGTCATTGCCGGTGATGGCGAAGATCGGCCACGGTTGGCGGCG
ATTGCGCGTGAACTCGGAGTGAGTGAACGGGTTCGCTTTCTGGGGAGTGTGCCGCGCCAGCATCTGCCGGCGCTCTACGC
TACTGTCGATCTGCTGCTGGCAACCAGCTATGCCAGCGAAACGTTTGGCATTGGGCCGGTCGAAGCGCAGGCGTGCGGAT
TACCGGTTGTAGCAACCCGTTTCGGAGGCTTTCCCGAAGTCGTCGCCGAGGGTCAGACCGGGCTACTGGTACCGCCTCGC
GATCCGGCGGCGCTGGCTGCGGCTGTCAATAGTCTGCTCTCCGATCCGGCACGTCGGGCAGCGCTGGCCGCGGCTGCGCC
GGCGTGGGCAGCCCAGTTTGCCTGGCCGGCGGTAGTGGATCGGATCGAGGCGGTCTATCGGGCTGTCCTGCAAACTAACT
GA

Upstream 100 bases:

>100_bases
AACGGAACGCCGGCAACGGTGGCGGCTGGCCATCTATCTGGGTTTGACCCTGGCCTTGTTTGTGGTGATGAAATTGACGC
TCTACACCATCTGGTAAGGT

Downstream 100 bases:

>100_bases
CGGTACGGTTTACCGGTTATCGTTACTCTACAACAACGTGTGACAAGCCATGCGCATTTTGATCATTGGACTTGGCGGTA
TCAGTCGTCATTTTCGTAAC

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MRIALYNLTTTTKIGGVESFVWDLARELAQRGHAVDILGGVGNRRETAPGVRVLTFPFISRRFWQAFPLLRRAYAEAKLL
ERLTMAVAALPTLVREKYQIIHLQKPYDLAPALLARRLSGARVILGCHGEDFYRGDTWLARRVDAAVSCSRFNAQTIAGR
YGFMPEVVFNGIDTSLFRPQPPDPTLRERLGVSSTVPLLLFVGRLQPWKGVETAIRALCHIDQAILVIAGDGEDRPRLAA
IARELGVSERVRFLGSVPRQHLPALYATVDLLLATSYASETFGIGPVEAQACGLPVVATRFGGFPEVVAEGQTGLLVPPR
DPAALAAAVNSLLSDPARRAALAAAAPAWAAQFAWPAVVDRIEAVYRAVLQTN

Sequences:

>Translated_373_residues
MRIALYNLTTTTKIGGVESFVWDLARELAQRGHAVDILGGVGNRRETAPGVRVLTFPFISRRFWQAFPLLRRAYAEAKLL
ERLTMAVAALPTLVREKYQIIHLQKPYDLAPALLARRLSGARVILGCHGEDFYRGDTWLARRVDAAVSCSRFNAQTIAGR
YGFMPEVVFNGIDTSLFRPQPPDPTLRERLGVSSTVPLLLFVGRLQPWKGVETAIRALCHIDQAILVIAGDGEDRPRLAA
IARELGVSERVRFLGSVPRQHLPALYATVDLLLATSYASETFGIGPVEAQACGLPVVATRFGGFPEVVAEGQTGLLVPPR
DPAALAAAVNSLLSDPARRAALAAAAPAWAAQFAWPAVVDRIEAVYRAVLQTN
>Mature_373_residues
MRIALYNLTTTTKIGGVESFVWDLARELAQRGHAVDILGGVGNRRETAPGVRVLTFPFISRRFWQAFPLLRRAYAEAKLL
ERLTMAVAALPTLVREKYQIIHLQKPYDLAPALLARRLSGARVILGCHGEDFYRGDTWLARRVDAAVSCSRFNAQTIAGR
YGFMPEVVFNGIDTSLFRPQPPDPTLRERLGVSSTVPLLLFVGRLQPWKGVETAIRALCHIDQAILVIAGDGEDRPRLAA
IARELGVSERVRFLGSVPRQHLPALYATVDLLLATSYASETFGIGPVEAQACGLPVVATRFGGFPEVVAEGQTGLLVPPR
DPAALAAAVNSLLSDPARRAALAAAAPAWAAQFAWPAVVDRIEAVYRAVLQTN

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=388, Percent_Identity=25.5154639175258, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1790061, Length=219, Percent_Identity=28.310502283105, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532709, Length=392, Percent_Identity=29.0816326530612, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI9755344, Length=393, Percent_Identity=24.1730279898219, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 40622; Mature: 40622

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIALYNLTTTTKIGGVESFVWDLARELAQRGHAVDILGGVGNRRETAPGVRVLTFPFIS
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEEHHHHH
RRFWQAFPLLRRAYAEAKLLERLTMAVAALPTLVREKYQIIHLQKPYDLAPALLARRLSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHCCC
ARVILGCHGEDFYRGDTWLARRVDAAVSCSRFNAQTIAGRYGFMPEVVFNGIDTSLFRPQ
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHCCCCCCCCCCC
PPDPTLRERLGVSSTVPLLLFVGRLQPWKGVETAIRALCHIDQAILVIAGDGEDRPRLAA
CCCHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHH
IARELGVSERVRFLGSVPRQHLPALYATVDLLLATSYASETFGIGPVEAQACGLPVVATR
HHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHH
FGGFPEVVAEGQTGLLVPPRDPAALAAAVNSLLSDPARRAALAAAAPAWAAQFAWPAVVD
CCCCHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHH
RIEAVYRAVLQTN
HHHHHHHHHHHCC
>Mature Secondary Structure
MRIALYNLTTTTKIGGVESFVWDLARELAQRGHAVDILGGVGNRRETAPGVRVLTFPFIS
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEEHHHHH
RRFWQAFPLLRRAYAEAKLLERLTMAVAALPTLVREKYQIIHLQKPYDLAPALLARRLSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHCCC
ARVILGCHGEDFYRGDTWLARRVDAAVSCSRFNAQTIAGRYGFMPEVVFNGIDTSLFRPQ
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHCCCCCCCCCCC
PPDPTLRERLGVSSTVPLLLFVGRLQPWKGVETAIRALCHIDQAILVIAGDGEDRPRLAA
CCCHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHH
IARELGVSERVRFLGSVPRQHLPALYATVDLLLATSYASETFGIGPVEAQACGLPVVATR
HHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHH
FGGFPEVVAEGQTGLLVPPRDPAALAAAVNSLLSDPARRAALAAAAPAWAAQFAWPAVVD
CCCCHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHH
RIEAVYRAVLQTN
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA