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The map label for this gene is atpB [H]

Identifier: 222526526

GI number: 222526526

Start: 4102053

End: 4102991

Strand: Reverse

Name: atpB [H]

Synonym: Chy400_3293

Alternate gene names: 222526526

Gene position: 4102991-4102053 (Counterclockwise)

Preceding gene: 222526527

Following gene: 222526525

Centisome position: 77.87

GC content: 52.93

Gene sequence:

>939_bases
TTGTCAACGCGGACTCGAAACATTCTCATTATTGTAGGAGCGCTCATCATTTCGATTGCCAGTCGCTTCTTCCTCTACAC
CGGCCCACCGCACGTAGAAGTCGCCGCTGAGGTCATTTTCGACGGTATTCCCGGCTTTCCAATCACCAATTCATTCGTTG
TTGCGATTATTATTGACATCTTCGTGATCGCTCTGGCTGTGGCTGCTACCCGCAACTTGCAAATGGTGCCACGCGGGTTG
CAGAACGTCATGGAGTTCATCCTCGAGTCACTCTACAATCTCTTCCGCAACATTAACGCCAAATATGTTGCCACTGCTTT
TCCGCTGGTAGCAACGATCTTCCTCTTCGTGCTCTTCGGCAACTGGTTTGGTTTGCTGCCCGGAGTAGGCTCAATTGGCG
TTTGCCACGAGAAGAAAGAAGAGCACGCGGTTGTCGATGAGCGTCTGGCGCTGGCAGCACCGGCTGCTCCGCTGAGCAGT
GTTGCAGCCGCCGAGGGTGAGGAGATTCACGATACCTGTGCTGCTCAGGGCAAGAAGCTGGTTCCGCTCTTCCGGGCACC
GGCAGCCGATCTCAATTTTACCTTCGCAATTGCTGTTATCTCGTTCGTCTTCATCGAGTACTGGGGCTTCCGGGCGCTTG
GCCCAGGGTATTTGAAGAAGTTCTTCAACACAAATGGCATCATGTCGTTTGTCGGGATCATTGAGTTTATCTCAGAGCTA
GTCAAGCCCTTCGCGTTGGCCTTCCGTCTTTTCGGCAATATCTTTGCCGGTGAAGTGTTGCTGGTCGTGATGGCATTCCT
GGTGCCACTCCTGTTACCACTGCCCTTCTACGGCTTTGAAGTGTTCGTTGGCTTCATCCAGGCGCTGATCTTTGCGCTGT
TAACCTATGCGTTCCTGAATATTGCCGTCACCGGCCACGATGAGGAGCACGCACATTGA

Upstream 100 bases:

>100_bases
ATCGAACAAGGAAGTTGTTGTTCGTCCATCGGGCAGCAGCGCACAGAGAGCAATACCCGGGCGCTGCATAGTTCCGACGT
TGTCGAGCAGGAGGTAGGCG

Downstream 100 bases:

>100_bases
TGAGTTCGGGCGGAATTATCCGCTAGAATGTTTGATATTGGGTTCGTCGCAGAGTCTGCTTTTAAGGAGGCATCTCAATC
ATGGAGGGTTTGAATCTCGT

Product: ATP synthase F0 subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSTRTRNILIIVGALIISIASRFFLYTGPPHVEVAAEVIFDGIPGFPITNSFVVAIIIDIFVIALAVAATRNLQMVPRGL
QNVMEFILESLYNLFRNINAKYVATAFPLVATIFLFVLFGNWFGLLPGVGSIGVCHEKKEEHAVVDERLALAAPAAPLSS
VAAAEGEEIHDTCAAQGKKLVPLFRAPAADLNFTFAIAVISFVFIEYWGFRALGPGYLKKFFNTNGIMSFVGIIEFISEL
VKPFALAFRLFGNIFAGEVLLVVMAFLVPLLLPLPFYGFEVFVGFIQALIFALLTYAFLNIAVTGHDEEHAH

Sequences:

>Translated_312_residues
MSTRTRNILIIVGALIISIASRFFLYTGPPHVEVAAEVIFDGIPGFPITNSFVVAIIIDIFVIALAVAATRNLQMVPRGL
QNVMEFILESLYNLFRNINAKYVATAFPLVATIFLFVLFGNWFGLLPGVGSIGVCHEKKEEHAVVDERLALAAPAAPLSS
VAAAEGEEIHDTCAAQGKKLVPLFRAPAADLNFTFAIAVISFVFIEYWGFRALGPGYLKKFFNTNGIMSFVGIIEFISEL
VKPFALAFRLFGNIFAGEVLLVVMAFLVPLLLPLPFYGFEVFVGFIQALIFALLTYAFLNIAVTGHDEEHAH
>Mature_311_residues
STRTRNILIIVGALIISIASRFFLYTGPPHVEVAAEVIFDGIPGFPITNSFVVAIIIDIFVIALAVAATRNLQMVPRGLQ
NVMEFILESLYNLFRNINAKYVATAFPLVATIFLFVLFGNWFGLLPGVGSIGVCHEKKEEHAVVDERLALAAPAAPLSSV
AAAEGEEIHDTCAAQGKKLVPLFRAPAADLNFTFAIAVISFVFIEYWGFRALGPGYLKKFFNTNGIMSFVGIIEFISELV
KPFALAFRLFGNIFAGEVLLVVMAFLVPLLLPLPFYGFEVFVGFIQALIFALLTYAFLNIAVTGHDEEHAH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=140, Percent_Identity=33.5714285714286, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 34152; Mature: 34021

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRTRNILIIVGALIISIASRFFLYTGPPHVEVAAEVIFDGIPGFPITNSFVVAIIIDI
CCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
FVIALAVAATRNLQMVPRGLQNVMEFILESLYNLFRNINAKYVATAFPLVATIFLFVLFG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
NWFGLLPGVGSIGVCHEKKEEHAVVDERLALAAPAAPLSSVAAAEGEEIHDTCAAQGKKL
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHCCCCC
VPLFRAPAADLNFTFAIAVISFVFIEYWGFRALGPGYLKKFFNTNGIMSFVGIIEFISEL
CHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
VKPFALAFRLFGNIFAGEVLLVVMAFLVPLLLPLPFYGFEVFVGFIQALIFALLTYAFLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IAVTGHDEEHAH
HHCCCCCCCCCC
>Mature Secondary Structure 
STRTRNILIIVGALIISIASRFFLYTGPPHVEVAAEVIFDGIPGFPITNSFVVAIIIDI
CCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
FVIALAVAATRNLQMVPRGLQNVMEFILESLYNLFRNINAKYVATAFPLVATIFLFVLFG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
NWFGLLPGVGSIGVCHEKKEEHAVVDERLALAAPAAPLSSVAAAEGEEIHDTCAAQGKKL
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHCCCCC
VPLFRAPAADLNFTFAIAVISFVFIEYWGFRALGPGYLKKFFNTNGIMSFVGIIEFISEL
CHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
VKPFALAFRLFGNIFAGEVLLVVMAFLVPLLLPLPFYGFEVFVGFIQALIFALLTYAFLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IAVTGHDEEHAH
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14621292 [H]