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The map label for this gene is yfkJ [H]

Identifier: 222526317

GI number: 222526317

Start: 3801806

End: 3802282

Strand: Reverse

Name: yfkJ [H]

Synonym: Chy400_3083

Alternate gene names: 222526317

Gene position: 3802282-3801806 (Counterclockwise)

Preceding gene: 222526318

Following gene: 222526314

Centisome position: 72.16

GC content: 56.39

Gene sequence:

>477_bases
ATGCACCGTAAAATACGTGTGTTGTTCGTCTGCATGGGGAATATCTGTCGTTCACCGATGGCCGAGGCGGTTTTTCGCCA
TCTGGTCAACGAAGCCGGCCTGAGCGAGCACTTTGAGATTGACTCAGCCGGAACCGGCGGCTGGCACGTGGGAGAACCAC
CACACCCTGGTACCCAGCGTGTGCTGGCCCGCCACAACATTTCGACCGCCGGTATACGGGCACGGCAGGTACGCAGTAGC
GATATCGATCAGTTCGACTACATCCTGGTGATGGATCACGAGAATCTGGCCGATCTGGGCCATTTTCATCCGAAAGCCCG
CGAACGCGCCCGGCTTTTGTTGAGTTTTGCGCCAGAATTGGGCACAGCGGAAGTTCCTGATCCTTACTACAATGGTCGCT
TCGATGAGGTCTACCATCTGATTGAGACGGCCTGTCGTCGACTACTGGCCCACATCCGGGAACGTGAAGGTTTGTGA

Upstream 100 bases:

>100_bases
GTTGGGCCACACGCCGGCTATTTCCGGCATGTGCGTCGAATCGATGAGGTGGCCGATGCGATTCTGTATGCATTGGCTGC
CGGTATGCTGTGAGGAGACT

Downstream 100 bases:

>100_bases
TCGGGGAGAATGCCGAGTCGCATTCCTGGGTAGAAGTAATCTCAAATCATCGACAAGCCTGGTATCGTAACGAGAACATA
CGTCGCGTCTGTGACCGGCA

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MHRKIRVLFVCMGNICRSPMAEAVFRHLVNEAGLSEHFEIDSAGTGGWHVGEPPHPGTQRVLARHNISTAGIRARQVRSS
DIDQFDYILVMDHENLADLGHFHPKARERARLLLSFAPELGTAEVPDPYYNGRFDEVYHLIETACRRLLAHIREREGL

Sequences:

>Translated_158_residues
MHRKIRVLFVCMGNICRSPMAEAVFRHLVNEAGLSEHFEIDSAGTGGWHVGEPPHPGTQRVLARHNISTAGIRARQVRSS
DIDQFDYILVMDHENLADLGHFHPKARERARLLLSFAPELGTAEVPDPYYNGRFDEVYHLIETACRRLLAHIREREGL
>Mature_158_residues
MHRKIRVLFVCMGNICRSPMAEAVFRHLVNEAGLSEHFEIDSAGTGGWHVGEPPHPGTQRVLARHNISTAGIRARQVRSS
DIDQFDYILVMDHENLADLGHFHPKARERARLLLSFAPELGTAEVPDPYYNGRFDEVYHLIETACRRLLAHIREREGL

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=148, Percent_Identity=42.5675675675676, Blast_Score=119, Evalue=1e-27,
Organism=Homo sapiens, GI6005988, Length=148, Percent_Identity=43.2432432432432, Blast_Score=117, Evalue=6e-27,
Organism=Homo sapiens, GI96304457, Length=76, Percent_Identity=52.6315789473684, Blast_Score=84, Evalue=6e-17,
Organism=Escherichia coli, GI1788375, Length=143, Percent_Identity=34.2657342657343, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI87081812, Length=142, Percent_Identity=31.6901408450704, Blast_Score=66, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325330, Length=141, Percent_Identity=36.1702127659575, Blast_Score=100, Evalue=8e-23,
Organism=Drosophila melanogaster, GI78706770, Length=158, Percent_Identity=41.7721518987342, Blast_Score=115, Evalue=8e-27,
Organism=Drosophila melanogaster, GI78706772, Length=158, Percent_Identity=41.7721518987342, Blast_Score=115, Evalue=8e-27,
Organism=Drosophila melanogaster, GI78711846, Length=159, Percent_Identity=36.4779874213836, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI78706766, Length=154, Percent_Identity=37.012987012987, Blast_Score=102, Evalue=8e-23,
Organism=Drosophila melanogaster, GI78706768, Length=154, Percent_Identity=37.012987012987, Blast_Score=102, Evalue=8e-23,
Organism=Drosophila melanogaster, GI78706764, Length=126, Percent_Identity=39.6825396825397, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24648069, Length=151, Percent_Identity=28.476821192053, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17975; Mature: 17975

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRKIRVLFVCMGNICRSPMAEAVFRHLVNEAGLSEHFEIDSAGTGGWHVGEPPHPGTQR
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCHHH
VLARHNISTAGIRARQVRSSDIDQFDYILVMDHENLADLGHFHPKARERARLLLSFAPEL
HHHHCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHCCHHHHHHHHHHHHHCCCC
GTAEVPDPYYNGRFDEVYHLIETACRRLLAHIREREGL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHRKIRVLFVCMGNICRSPMAEAVFRHLVNEAGLSEHFEIDSAGTGGWHVGEPPHPGTQR
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCHHH
VLARHNISTAGIRARQVRSSDIDQFDYILVMDHENLADLGHFHPKARERARLLLSFAPEL
HHHHCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHCCHHHHHHHHHHHHHCCCC
GTAEVPDPYYNGRFDEVYHLIETACRRLLAHIREREGL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]