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The map label for this gene is accA1 [H]

Identifier: 222526302

GI number: 222526302

Start: 3785678

End: 3787642

Strand: Reverse

Name: accA1 [H]

Synonym: Chy400_3068

Alternate gene names: 222526302

Gene position: 3787642-3785678 (Counterclockwise)

Preceding gene: 222526303

Following gene: 222526301

Centisome position: 71.89

GC content: 62.95

Gene sequence:

>1965_bases
ATGTTCAACCGTATCCTGATCGCTAATCGCGGCGAGATTGCCGTGCGTATTATCCGCGCCTGTCGCGAACTGGGCATTAG
CCCGGTGGTTGTCTACTCGGCTGCCGATGCCGGTGCGCTGCACGTGCGCATGGCCGATGCTGCCGCCTTGATCGGCCCAC
CCCCTGCCGCACAAAGCTATTTGCGTGCCGAGGCCATCGTTGAAGCAGCGCTTCAACTGGGTGCCCAGGCCATACACCCC
GGCTACGGCTTTCTCAGCGAAAGTGTCAAACTGGCCGAACAGTGTGCAGCGGCTGGGATCACGTTTATCGGCCCGCCACC
ATCTGCGATTGCTGCCATGGGTGGTAAAGCGGAAGCACGTGCGCTGGCGCAGGCCGCCGGTGTGCCGGTGGTGCCGGGGT
ATGATGGTGAAGATCAGAGTGATGAGCGCCTGCTGGCCGAGGCGCACCGTATCGGGCCACCACTGCTGATCAAGGCGAGT
GCTGGTGGCGGTGGCAAGGGCATGCGTTCCGTTGGTGATCTGGCCGCAGTACCCGCCGCTATCGAAGGCGCCCGCCGTGA
AGCCCGTGCCGCCTTCGGCGATGACCGGCTGATCATCGAGCGTCTCGTCCTCCGCCCCCGCCATGTTGAGATTCAGGTGC
TGGCCGATCAGCACGGCAATGTCGTTCACCTCGGCGAGCGCGACTGTTCGATCCAGCGCCGCCACCAGAAGGTGGTCGAA
GAGGCACCATCGCCGGCGCTGACCCCTGCTCTACGCAACGCGATGGGCCAGGCTGCGGTGGCGGTCGCACGAGCGGCAGG
GTATGTCAATGCCGGTACGGTTGAATTCATTCTTACCCCTGATGGTGAATTCTACTTTCTGGAGATGAACACTCGCTTGC
AGGTTGAGCATCCGGTCACTGAACTGATTTGCGGTTATGACCTGGTGCACTTGCAGATCGCGATTGCCGCCGGTCAGCCA
CTTCCGTTCCGACAAGAGGATGTCACGGTGCGCGGTCACGCAATTGAAGTGCGTCTCTACGCCGAAGACCCTCGCACCTA
TCTGCCGGCGGTTGGGAAGGTGGCGCTGTTTGTGCCGCCACAAGGGCCGGGCGTGCGCGTCGATGCCGGCCTGACCAGCG
GCGATGAAGTGACCGTCCATTATGACCCGCTGTTGGCCAAGATTATTGTGGCCGGAGCTGATCGTCAGCAGGCGGTGGCC
CGGCTGCGCCGGGTGCTGCGCGAGATGGTGGTGCTGGGGCCAACGACCAATTTACCGCTCTTGCAGGCGATTGCCGAGCA
CCCGGCATTTGCCGCCGGTGCTACTCATACCGGCTTCCTGAGTGAACACGAAGGACTGGTACCGCCACCCGCACCACCAC
CGTGCGAAGTGCTGGTCGCCGCCGCCGTCCTGACAGTTACCGCCGAACCACCGGCTCGCGACCCGCTGGCCAGGGTCTGG
CGTCTGGGTGGCGACACCATCCCGCTCACTTTTAGCTCCCATGGCGATCACCGCCTGCGGGTAGCGCCGTCAACCAGCGG
CTGGCATATCCATGGCGATGGCTGGGGTGTGCAGACAACACTGGTCTATCGTGGTGACCACGAACTGGCTCTGGACATTG
ATGGGCAACGCCAGCAGTTCTTCTTTGCGCAGGCCGATGACGGCTGGCTGATCGCATGGCGTGGTGAAGCGTACCATCTT
ACCCGCCCCGCTCCCTTGACCGCCGATAGCGTGACGCGCAGTGGTGATCAGAATGCGGCCAGCTTCACTGCGCCGATGCC
CGGCACCATTGTGCGTATCCACGTTGCCGTCGGTGAGCAGGTACGCGAAGGGCAACCACTGCTGGTGTTGGAGGCGATGA
AGATGGAGCACACAGTCGTCGCTCCGTATGCCGGCATTGTCCGTCGTCTACCCTACCAGGCCGGTGCCAGCGTCGCGGCT
GGCGCTCACCTCGTTGACCTTGAACCAATATCGGTATCGGAATAG

Upstream 100 bases:

>100_bases
TCGATCTCGGCTTCGACGAGATTTATGTGCATAACGTTGGTCGCAATCAAGCGGAATGGATTAAAGCCTACGGAGAAGCG
GTTTTGCCCAAATTACGCCC

Downstream 100 bases:

>100_bases
CTACTCTGAGAGATAACAGGCAACGTATGGCATCGCAACAGGCTACTCAACCTGCCAAACCACCGGCAACCGCTAATCAG
AAACCACCGGCGAAACCAAA

Product: carbamoyl-phosphate synthase L chain ATP-binding

Products: NA

Alternate protein names: Biotin carboxylase; Biotin carboxyl carrier protein; BCCP [H]

Number of amino acids: Translated: 654; Mature: 654

Protein sequence:

>654_residues
MFNRILIANRGEIAVRIIRACRELGISPVVVYSAADAGALHVRMADAAALIGPPPAAQSYLRAEAIVEAALQLGAQAIHP
GYGFLSESVKLAEQCAAAGITFIGPPPSAIAAMGGKAEARALAQAAGVPVVPGYDGEDQSDERLLAEAHRIGPPLLIKAS
AGGGGKGMRSVGDLAAVPAAIEGARREARAAFGDDRLIIERLVLRPRHVEIQVLADQHGNVVHLGERDCSIQRRHQKVVE
EAPSPALTPALRNAMGQAAVAVARAAGYVNAGTVEFILTPDGEFYFLEMNTRLQVEHPVTELICGYDLVHLQIAIAAGQP
LPFRQEDVTVRGHAIEVRLYAEDPRTYLPAVGKVALFVPPQGPGVRVDAGLTSGDEVTVHYDPLLAKIIVAGADRQQAVA
RLRRVLREMVVLGPTTNLPLLQAIAEHPAFAAGATHTGFLSEHEGLVPPPAPPPCEVLVAAAVLTVTAEPPARDPLARVW
RLGGDTIPLTFSSHGDHRLRVAPSTSGWHIHGDGWGVQTTLVYRGDHELALDIDGQRQQFFFAQADDGWLIAWRGEAYHL
TRPAPLTADSVTRSGDQNAASFTAPMPGTIVRIHVAVGEQVREGQPLLVLEAMKMEHTVVAPYAGIVRRLPYQAGASVAA
GAHLVDLEPISVSE

Sequences:

>Translated_654_residues
MFNRILIANRGEIAVRIIRACRELGISPVVVYSAADAGALHVRMADAAALIGPPPAAQSYLRAEAIVEAALQLGAQAIHP
GYGFLSESVKLAEQCAAAGITFIGPPPSAIAAMGGKAEARALAQAAGVPVVPGYDGEDQSDERLLAEAHRIGPPLLIKAS
AGGGGKGMRSVGDLAAVPAAIEGARREARAAFGDDRLIIERLVLRPRHVEIQVLADQHGNVVHLGERDCSIQRRHQKVVE
EAPSPALTPALRNAMGQAAVAVARAAGYVNAGTVEFILTPDGEFYFLEMNTRLQVEHPVTELICGYDLVHLQIAIAAGQP
LPFRQEDVTVRGHAIEVRLYAEDPRTYLPAVGKVALFVPPQGPGVRVDAGLTSGDEVTVHYDPLLAKIIVAGADRQQAVA
RLRRVLREMVVLGPTTNLPLLQAIAEHPAFAAGATHTGFLSEHEGLVPPPAPPPCEVLVAAAVLTVTAEPPARDPLARVW
RLGGDTIPLTFSSHGDHRLRVAPSTSGWHIHGDGWGVQTTLVYRGDHELALDIDGQRQQFFFAQADDGWLIAWRGEAYHL
TRPAPLTADSVTRSGDQNAASFTAPMPGTIVRIHVAVGEQVREGQPLLVLEAMKMEHTVVAPYAGIVRRLPYQAGASVAA
GAHLVDLEPISVSE
>Mature_654_residues
MFNRILIANRGEIAVRIIRACRELGISPVVVYSAADAGALHVRMADAAALIGPPPAAQSYLRAEAIVEAALQLGAQAIHP
GYGFLSESVKLAEQCAAAGITFIGPPPSAIAAMGGKAEARALAQAAGVPVVPGYDGEDQSDERLLAEAHRIGPPLLIKAS
AGGGGKGMRSVGDLAAVPAAIEGARREARAAFGDDRLIIERLVLRPRHVEIQVLADQHGNVVHLGERDCSIQRRHQKVVE
EAPSPALTPALRNAMGQAAVAVARAAGYVNAGTVEFILTPDGEFYFLEMNTRLQVEHPVTELICGYDLVHLQIAIAAGQP
LPFRQEDVTVRGHAIEVRLYAEDPRTYLPAVGKVALFVPPQGPGVRVDAGLTSGDEVTVHYDPLLAKIIVAGADRQQAVA
RLRRVLREMVVLGPTTNLPLLQAIAEHPAFAAGATHTGFLSEHEGLVPPPAPPPCEVLVAAAVLTVTAEPPARDPLARVW
RLGGDTIPLTFSSHGDHRLRVAPSTSGWHIHGDGWGVQTTLVYRGDHELALDIDGQRQQFFFAQADDGWLIAWRGEAYHL
TRPAPLTADSVTRSGDQNAASFTAPMPGTIVRIHVAVGEQVREGQPLLVLEAMKMEHTVVAPYAGIVRRLPYQAGASVAA
GAHLVDLEPISVSE

Specific function: This protein carries two functions:biotin carboxyl carrier protein and biotin carboxyltransferase [H]

COG id: COG4770

COG function: function code I; Acetyl/propionyl-CoA carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI116805327, Length=672, Percent_Identity=43.6011904761905, Blast_Score=542, Evalue=1e-154,
Organism=Homo sapiens, GI189095269, Length=674, Percent_Identity=40.8011869436202, Blast_Score=479, Evalue=1e-135,
Organism=Homo sapiens, GI65506442, Length=674, Percent_Identity=40.8011869436202, Blast_Score=479, Evalue=1e-135,
Organism=Homo sapiens, GI295821183, Length=662, Percent_Identity=40.6344410876133, Blast_Score=457, Evalue=1e-128,
Organism=Homo sapiens, GI106049528, Length=451, Percent_Identity=46.5631929046563, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI106049295, Length=451, Percent_Identity=46.5631929046563, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI106049292, Length=451, Percent_Identity=46.5631929046563, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI38679971, Length=731, Percent_Identity=28.0437756497948, Blast_Score=248, Evalue=9e-66,
Organism=Homo sapiens, GI38679974, Length=731, Percent_Identity=28.0437756497948, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI38679960, Length=731, Percent_Identity=28.0437756497948, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI38679977, Length=731, Percent_Identity=28.0437756497948, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI38679967, Length=731, Percent_Identity=28.0437756497948, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI134142062, Length=733, Percent_Identity=28.7858117326057, Blast_Score=236, Evalue=4e-62,
Organism=Escherichia coli, GI1789654, Length=449, Percent_Identity=50.5567928730512, Blast_Score=418, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI71987519, Length=665, Percent_Identity=43.0075187969925, Blast_Score=514, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI17567343, Length=477, Percent_Identity=46.7505241090147, Blast_Score=432, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17562816, Length=449, Percent_Identity=45.2115812917595, Blast_Score=368, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI133931226, Length=680, Percent_Identity=27.7941176470588, Blast_Score=227, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI71997168, Length=504, Percent_Identity=28.968253968254, Blast_Score=194, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71997163, Length=406, Percent_Identity=31.7733990147783, Blast_Score=192, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6319685, Length=447, Percent_Identity=43.6241610738255, Blast_Score=353, Evalue=5e-98,
Organism=Saccharomyces cerevisiae, GI6319695, Length=448, Percent_Identity=42.1875, Blast_Score=332, Evalue=1e-91,
Organism=Saccharomyces cerevisiae, GI6321376, Length=449, Percent_Identity=42.9844097995546, Blast_Score=324, Evalue=3e-89,
Organism=Saccharomyces cerevisiae, GI6324343, Length=725, Percent_Identity=29.6551724137931, Blast_Score=246, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6323863, Length=673, Percent_Identity=28.3803863298663, Blast_Score=220, Evalue=7e-58,
Organism=Drosophila melanogaster, GI24651757, Length=675, Percent_Identity=44.1481481481481, Blast_Score=513, Evalue=1e-145,
Organism=Drosophila melanogaster, GI24651759, Length=638, Percent_Identity=43.730407523511, Blast_Score=473, Evalue=1e-133,
Organism=Drosophila melanogaster, GI24652212, Length=445, Percent_Identity=45.1685393258427, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24652210, Length=445, Percent_Identity=45.1685393258427, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24652214, Length=445, Percent_Identity=45.1685393258427, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI19921944, Length=445, Percent_Identity=45.1685393258427, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24652216, Length=445, Percent_Identity=45.1685393258427, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI281363050, Length=445, Percent_Identity=45.1685393258427, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24652224, Length=445, Percent_Identity=45.1685393258427, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24652222, Length=445, Percent_Identity=45.1685393258427, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24652220, Length=445, Percent_Identity=45.1685393258427, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24652218, Length=445, Percent_Identity=45.1685393258427, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI161076409, Length=727, Percent_Identity=29.2984869325997, Blast_Score=238, Evalue=7e-63,
Organism=Drosophila melanogaster, GI24586458, Length=727, Percent_Identity=29.2984869325997, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI161076407, Length=727, Percent_Identity=29.2984869325997, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI24586460, Length=727, Percent_Identity=29.2984869325997, Blast_Score=238, Evalue=9e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR001882
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2 [H]

EC number: =6.3.4.14 [H]

Molecular weight: Translated: 69385; Mature: 69385

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS50975 ATP_GRASP ; PS00867 CPSASE_2 ; PS50979 BC ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNRILIANRGEIAVRIIRACRELGISPVVVYSAADAGALHVRMADAAALIGPPPAAQSY
CCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCEECCCCHHHHHH
LRAEAIVEAALQLGAQAIHPGYGFLSESVKLAEQCAAAGITFIGPPPSAIAAMGGKAEAR
HHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHCCCCHHHH
ALAQAAGVPVVPGYDGEDQSDERLLAEAHRIGPPLLIKASAGGGGKGMRSVGDLAAVPAA
HHHHHCCCCEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
IEGARREARAAFGDDRLIIERLVLRPRHVEIQVLADQHGNVVHLGERDCSIQRRHQKVVE
HHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHH
EAPSPALTPALRNAMGQAAVAVARAAGYVNAGTVEFILTPDGEFYFLEMNTRLQVEHPVT
HCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCEEEEEECCCCCEEEEEECCEEEECCCHH
ELICGYDLVHLQIAIAAGQPLPFRQEDVTVRGHAIEVRLYAEDPRTYLPAVGKVALFVPP
HHHHCCEEEEEEEEEECCCCCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCEEEEEECC
QGPGVRVDAGLTSGDEVTVHYDPLLAKIIVAGADRQQAVARLRRVLREMVVLGPTTNLPL
CCCCEEEECCCCCCCEEEEEECHHEEEHHHCCCCHHHHHHHHHHHHHHHHEECCCCCCHH
LQAIAEHPAFAAGATHTGFLSEHEGLVPPPAPPPCEVLVAAAVLTVTAEPPARDPLARVW
HHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCCCHHHHHH
RLGGDTIPLTFSSHGDHRLRVAPSTSGWHIHGDGWGVQTTLVYRGDHELALDIDGQRQQF
HCCCCEEEEEECCCCCEEEEEECCCCCEEEECCCCCEEEEEEEECCCEEEEEECCCCEEE
FFAQADDGWLIAWRGEAYHLTRPAPLTADSVTRSGDQNAASFTAPMPGTIVRIHVAVGEQ
EEEECCCCEEEEEECCEEEECCCCCCCHHHHHCCCCCCCCEEECCCCCEEEEEEEEECHH
VREGQPLLVLEAMKMEHTVVAPYAGIVRRLPYQAGASVAAGAHLVDLEPISVSE
HHCCCCEEEEEECCCCCEEECHHHHHHHHCCCCCCCCHHCCCEEEEECCCCCCC
>Mature Secondary Structure
MFNRILIANRGEIAVRIIRACRELGISPVVVYSAADAGALHVRMADAAALIGPPPAAQSY
CCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCEECCCCHHHHHH
LRAEAIVEAALQLGAQAIHPGYGFLSESVKLAEQCAAAGITFIGPPPSAIAAMGGKAEAR
HHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHCCCCHHHH
ALAQAAGVPVVPGYDGEDQSDERLLAEAHRIGPPLLIKASAGGGGKGMRSVGDLAAVPAA
HHHHHCCCCEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
IEGARREARAAFGDDRLIIERLVLRPRHVEIQVLADQHGNVVHLGERDCSIQRRHQKVVE
HHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHH
EAPSPALTPALRNAMGQAAVAVARAAGYVNAGTVEFILTPDGEFYFLEMNTRLQVEHPVT
HCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCEEEEEECCCCCEEEEEECCEEEECCCHH
ELICGYDLVHLQIAIAAGQPLPFRQEDVTVRGHAIEVRLYAEDPRTYLPAVGKVALFVPP
HHHHCCEEEEEEEEEECCCCCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCEEEEEECC
QGPGVRVDAGLTSGDEVTVHYDPLLAKIIVAGADRQQAVARLRRVLREMVVLGPTTNLPL
CCCCEEEECCCCCCCEEEEEECHHEEEHHHCCCCHHHHHHHHHHHHHHHHEECCCCCCHH
LQAIAEHPAFAAGATHTGFLSEHEGLVPPPAPPPCEVLVAAAVLTVTAEPPARDPLARVW
HHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCCCHHHHHH
RLGGDTIPLTFSSHGDHRLRVAPSTSGWHIHGDGWGVQTTLVYRGDHELALDIDGQRQQF
HCCCCEEEEEECCCCCEEEEEECCCCCEEEECCCCCEEEEEEEECCCEEEEEECCCCEEE
FFAQADDGWLIAWRGEAYHLTRPAPLTADSVTRSGDQNAASFTAPMPGTIVRIHVAVGEQ
EEEECCCCEEEEEECCEEEECCCCCCCHHHHHCCCCCCCCEEECCCCCEEEEEEEEECHH
VREGQPLLVLEAMKMEHTVVAPYAGIVRRLPYQAGASVAAGAHLVDLEPISVSE
HHCCCCEEEEEECCCCCEEECHHHHHHHHCCCCCCCCHHCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]