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The map label for this gene is silR [H]

Identifier: 222526285

GI number: 222526285

Start: 3763891

End: 3765474

Strand: Direct

Name: silR [H]

Synonym: Chy400_3051

Alternate gene names: 222526285

Gene position: 3763891-3765474 (Clockwise)

Preceding gene: 222526284

Following gene: 222526286

Centisome position: 71.44

GC content: 53.16

Gene sequence:

>1584_bases
ATGAGTAAATTTTCTCCGGAGGTTGAACGGTTTATTCATCAGTATGTGTCACCTCTTACGTCGTTGCAGAGTGCTGTTGA
TCTCCTCGCACACCACTATGGACAGAGTACTGATCAGCGCCTCAACAATCTGGTCGCTTCATTACAGCGCTCAACCGTGC
GTTTGCGCCAGTTTGCTCAGTTGCTGACAGAACATCTTCAACAAGAGGGCGACGACATCGTTGTCCGTGTCCCACGGGCC
TGGTATTGGCAGGATCAGCACGCTGCACCATCTGCAGGCGCTCCACCGTCTGTATCGCTAGGGTCGGGTTCAGCAGTGCT
GGTTGGCGGAGCAGCCCTCGATGATCTGGCTGATCTGCTCCACAATGCCGGCTGGCAGGTTGAACGGGTGTCATCATGCG
CTGCCGGCCTGGATATCGCCCGTTACCGCCGTCCACGTTTGCTGGTCATTGCCGGCACCACTGCCGACATCGAGCCGGCC
TTATGTGCGCAAATTGTGCATACCGATCCAGAGACACGCGGTGTGGTTGTGGCAATGGCCACCCGTGATCGGTCAGTCCG
TCCTGTAACAGGCATTCCCTATATCGACCTGCAACAACCGCTGCTCGAGCAGCTCCATCGCCTGCTGTCAATGCATCACC
AGGCCGGGCAGAGCGTACCGCGGATTTTGCTGGTTGATGATGAACTGGATATTCGGGTTATCCTTAGCCAGCAATTAACG
GATGCCGGTTTTGTGGTGGTCACGGCCCCTGATGCGACAACGGCATTACGGCTGATGCATGAACAATTCTTCGACCTGGT
CATCCTGGATCGACTACTGCCCGATAGTGATGGCTTAAACGTGCTACGGACAATTCGCTCGTCCGGTACGACACGCCTGA
TCCCGGTGATGCTGCTTTCAGCGGTGAGTTCGTTGGATGAGAAGGTACGCAGTCTGCAATTAGGTGCCGATGATTACGTG
GTGAAACCATGTAGTGCGGCAGAACTGGCAGCACGTATTCGTTCGATCTTGCGCCGGAGCGAACGTGAGAGCAGTCTGAA
TCCAATTTCACGCTTACCCGGCAATACGACGATTGAACAGGTTATTCATGAGCGATTGGTCAAACAGGAACCTTTTGCGG
TTGGCTATATCGATCTCGACAATTTTAAAGGGTATAATGATCATTACGGCTTCTTCAAAGGTGATGCAGTCATCTTACAC
GCTGCCCGTTTGTTGTCTGAGGTTGTCCACTGGCAGGGAACGCCTGACGATTTTCTGGGTCATTTAGGTGGTGATGATTT
TGTGCTGGTTTCAACCCTCGAACGGGCGCAGCAGATCGCACAGGCAATGATCGAACGATTCGATGCTACTATTCCGTACT
TCTATGCACCTGAGGATCGTCAGCGTGGTTATATTGTTGGACACGACCGTCAGGGACGACCGTGCCGATATCCACTGTTG
AGTGTCTCGATTGCAATTGTACCGGTGACGCCGTCGCGCTATCAGCAGCCATACGAGATTGCAATGCGCGCAGCTATTGT
GAAGCGACAGTCGAAATCGGTCACTGGGAGTTGTGTGATTGTCGATAATGAAGAAAGAGGATAG

Upstream 100 bases:

>100_bases
GCATTTGCGCTTGGTGCACGTGGTTTTCTCGAGAAGCCGGTCTCGGCTGAACGACTGATTGCCACGTTGACCTCCGTCAT
TCCAGCAGATGAGGGCAGTC

Downstream 100 bases:

>100_bases
CAATGCCTTCTGTACCGGTACCAACGATTGTAGAACGCACGAGCCGTGGAGAGCGAAGCTGGGATATTTTTTCGCGCCTG
CTGAAAGAGCGAGTGGTGTT

Product: response regulator receiver modulated diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MSKFSPEVERFIHQYVSPLTSLQSAVDLLAHHYGQSTDQRLNNLVASLQRSTVRLRQFAQLLTEHLQQEGDDIVVRVPRA
WYWQDQHAAPSAGAPPSVSLGSGSAVLVGGAALDDLADLLHNAGWQVERVSSCAAGLDIARYRRPRLLVIAGTTADIEPA
LCAQIVHTDPETRGVVVAMATRDRSVRPVTGIPYIDLQQPLLEQLHRLLSMHHQAGQSVPRILLVDDELDIRVILSQQLT
DAGFVVVTAPDATTALRLMHEQFFDLVILDRLLPDSDGLNVLRTIRSSGTTRLIPVMLLSAVSSLDEKVRSLQLGADDYV
VKPCSAAELAARIRSILRRSERESSLNPISRLPGNTTIEQVIHERLVKQEPFAVGYIDLDNFKGYNDHYGFFKGDAVILH
AARLLSEVVHWQGTPDDFLGHLGGDDFVLVSTLERAQQIAQAMIERFDATIPYFYAPEDRQRGYIVGHDRQGRPCRYPLL
SVSIAIVPVTPSRYQQPYEIAMRAAIVKRQSKSVTGSCVIVDNEERG

Sequences:

>Translated_527_residues
MSKFSPEVERFIHQYVSPLTSLQSAVDLLAHHYGQSTDQRLNNLVASLQRSTVRLRQFAQLLTEHLQQEGDDIVVRVPRA
WYWQDQHAAPSAGAPPSVSLGSGSAVLVGGAALDDLADLLHNAGWQVERVSSCAAGLDIARYRRPRLLVIAGTTADIEPA
LCAQIVHTDPETRGVVVAMATRDRSVRPVTGIPYIDLQQPLLEQLHRLLSMHHQAGQSVPRILLVDDELDIRVILSQQLT
DAGFVVVTAPDATTALRLMHEQFFDLVILDRLLPDSDGLNVLRTIRSSGTTRLIPVMLLSAVSSLDEKVRSLQLGADDYV
VKPCSAAELAARIRSILRRSERESSLNPISRLPGNTTIEQVIHERLVKQEPFAVGYIDLDNFKGYNDHYGFFKGDAVILH
AARLLSEVVHWQGTPDDFLGHLGGDDFVLVSTLERAQQIAQAMIERFDATIPYFYAPEDRQRGYIVGHDRQGRPCRYPLL
SVSIAIVPVTPSRYQQPYEIAMRAAIVKRQSKSVTGSCVIVDNEERG
>Mature_526_residues
SKFSPEVERFIHQYVSPLTSLQSAVDLLAHHYGQSTDQRLNNLVASLQRSTVRLRQFAQLLTEHLQQEGDDIVVRVPRAW
YWQDQHAAPSAGAPPSVSLGSGSAVLVGGAALDDLADLLHNAGWQVERVSSCAAGLDIARYRRPRLLVIAGTTADIEPAL
CAQIVHTDPETRGVVVAMATRDRSVRPVTGIPYIDLQQPLLEQLHRLLSMHHQAGQSVPRILLVDDELDIRVILSQQLTD
AGFVVVTAPDATTALRLMHEQFFDLVILDRLLPDSDGLNVLRTIRSSGTTRLIPVMLLSAVSSLDEKVRSLQLGADDYVV
KPCSAAELAARIRSILRRSERESSLNPISRLPGNTTIEQVIHERLVKQEPFAVGYIDLDNFKGYNDHYGFFKGDAVILHA
ARLLSEVVHWQGTPDDFLGHLGGDDFVLVSTLERAQQIAQAMIERFDATIPYFYAPEDRQRGYIVGHDRQGRPCRYPLLS
VSIAIVPVTPSRYQQPYEIAMRAAIVKRQSKSVTGSCVIVDNEERG

Specific function: Component of the sil cation-efflux system that confers resistance to silver. Probable member of a two-component regulatory system silS/silR [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=120, Percent_Identity=41.6666666666667, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786599, Length=168, Percent_Identity=32.1428571428571, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789809, Length=142, Percent_Identity=35.9154929577465, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87082012, Length=132, Percent_Identity=39.3939393939394, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787375, Length=120, Percent_Identity=40, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1789402, Length=125, Percent_Identity=36.8, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790552, Length=144, Percent_Identity=38.8888888888889, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1786911, Length=145, Percent_Identity=35.8620689655172, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788394, Length=131, Percent_Identity=32.824427480916, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=37.5, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790860, Length=131, Percent_Identity=35.1145038167939, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI2367329, Length=120, Percent_Identity=40, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=34.1666666666667, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790863, Length=122, Percent_Identity=33.6065573770492, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787229, Length=118, Percent_Identity=32.2033898305085, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=35.3448275862069, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 58440; Mature: 58309

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFSPEVERFIHQYVSPLTSLQSAVDLLAHHYGQSTDQRLNNLVASLQRSTVRLRQFAQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLTEHLQQEGDDIVVRVPRAWYWQDQHAAPSAGAPPSVSLGSGSAVLVGGAALDDLADLL
HHHHHHHCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHH
HNAGWQVERVSSCAAGLDIARYRRPRLLVIAGTTADIEPALCAQIVHTDPETRGVVVAMA
HCCCCCHHHHHHHHHCCHHHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEE
TRDRSVRPVTGIPYIDLQQPLLEQLHRLLSMHHQAGQSVPRILLVDDELDIRVILSQQLT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEHHCC
DAGFVVVTAPDATTALRLMHEQFFDLVILDRLLPDSDGLNVLRTIRSSGTTRLIPVMLLS
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHH
AVSSLDEKVRSLQLGADDYVVKPCSAAELAARIRSILRRSERESSLNPISRLPGNTTIEQ
HHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHH
VIHERLVKQEPFAVGYIDLDNFKGYNDHYGFFKGDAVILHAARLLSEVVHWQGTPDDFLG
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCCHHHHH
HLGGDDFVLVSTLERAQQIAQAMIERFDATIPYFYAPEDRQRGYIVGHDRQGRPCRYPLL
HCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEECCCCCCCCCCCEE
SVSIAIVPVTPSRYQQPYEIAMRAAIVKRQSKSVTGSCVIVDNEERG
EEEEEEEECCHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
>Mature Secondary Structure 
SKFSPEVERFIHQYVSPLTSLQSAVDLLAHHYGQSTDQRLNNLVASLQRSTVRLRQFAQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLTEHLQQEGDDIVVRVPRAWYWQDQHAAPSAGAPPSVSLGSGSAVLVGGAALDDLADLL
HHHHHHHCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHH
HNAGWQVERVSSCAAGLDIARYRRPRLLVIAGTTADIEPALCAQIVHTDPETRGVVVAMA
HCCCCCHHHHHHHHHCCHHHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEE
TRDRSVRPVTGIPYIDLQQPLLEQLHRLLSMHHQAGQSVPRILLVDDELDIRVILSQQLT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEHHCC
DAGFVVVTAPDATTALRLMHEQFFDLVILDRLLPDSDGLNVLRTIRSSGTTRLIPVMLLS
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHH
AVSSLDEKVRSLQLGADDYVVKPCSAAELAARIRSILRRSERESSLNPISRLPGNTTIEQ
HHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHH
VIHERLVKQEPFAVGYIDLDNFKGYNDHYGFFKGDAVILHAARLLSEVVHWQGTPDDFLG
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCCHHHHH
HLGGDDFVLVSTLERAQQIAQAMIERFDATIPYFYAPEDRQRGYIVGHDRQGRPCRYPLL
HCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEECCCCCCCCCCCEE
SVSIAIVPVTPSRYQQPYEIAMRAAIVKRQSKSVTGSCVIVDNEERG
EEEEEEEECCHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9930866 [H]