Click here to switch to the map view.

The map label for this gene is mpg1 [H]

Identifier: 222526147

GI number: 222526147

Start: 3588424

End: 3589536

Strand: Direct

Name: mpg1 [H]

Synonym: Chy400_2904

Alternate gene names: 222526147

Gene position: 3588424-3589536 (Clockwise)

Preceding gene: 222526146

Following gene: 222526149

Centisome position: 68.11

GC content: 55.88

Gene sequence:

>1113_bases
ATGAAAGCTGTTATTCTTGTTGGTGGGCAGGGATCACGTTTGCGCCCGCTGACCTGCCGGACACCCAAACCAATGTTGCC
GCTGGTCAATCAGCCATTCATCGAGTGGATGTTGCTGCGTCTCCGCGACTATGGTATTCGAGATGTCATCCTGGCCGTGC
AATATCTGGCCGACCGCTTCCGCACAGCGCTCGGCGATGGTTCACGACTGGGTATGAATGTCCACATCGTTGAAGAGCCG
GAACCACGCGGTACTGCCGGCGCGGTGAAACACGTCGAGCACATGCTTGATGGGACAACGTTTGTCTTCAATGGCGATGT
GATGACCGACCTCGATTTGCAGGCAATGCTCGATTTTCACCGCGAGCGTGGCAGCAAGGTGACCATCTCGCTCACGCCGG
TTGATGATCCGACGCAGTTTGGGCTGGTCGAGACTGAACGCGATGGACGTGTGCGCCGTTTTCTTGAGAAGCCCCGCGCC
GAAGACATCACGACCAATCTGGTCAACGCCGGTACCTATCTGATTGAACCGGAGATTTTCCGCTACGTGCCCCCGAATCA
GTTCTATATGTTCGAGCGCGGCCTCTTCCCGGTGGTGCTTCAGACCGGTGATCCGATGTACGGCTTTCCGTCACGCGCTT
ACTGGACGGATATTGGCAAGCCGCAAACGTATCTTGATGTTCACCATGACATTTTGATCGGGAAAGTGCAGTACCACTTC
CGTGGACAACAGATTGGCGAGCGTGTCTGGCTTGAAGGCGAAGCAGAGATTCACTCTAGCGCGCAGATTGTTGGTCCGGT
GGTCATCGGCCACGGGACACGGATTGGGCGCGGGACACGGATTATTGGCCCAACCGTTATCGGCTCGCGCTGCACGATTG
GTCCTGAATGCCAGATCGAAGGTGTGGTCATGTGGGATGGGAATACGATTGAAGAGGGCAGTACACTCCGTAACTGTGTG
CTGGGGTACAACAATCGGATTGGCGAGCGATCCCACATTATTGACGGCACTATCATCAGTGATGAGTGTCAGATTGGTCA
GGAAAACCGGCTTGAACGCGGCATCCGTATCTGGCCGGGTACCACCCTGGGTGACCGGGCAGTTTCGTTCTGA

Upstream 100 bases:

>100_bases
ACCCAAACCCCGGTTTGCGGTAAACTTTTTGTGGTCTGATGGCGTTATACTACGCCTATCTATCAGGAGCGTTGTGTACA
TTTAGTAAGTAGAACTGTCT

Downstream 100 bases:

>100_bases
GAGGCTATCCGATCCGTGGGTTGGCCCGAAAGATTACCCGCACGAATTGCAGTTCACCGCAAAAGATTATCCTGGCACCA
TCCAGTCGGGGCGCACGGTC

Product: nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MKAVILVGGQGSRLRPLTCRTPKPMLPLVNQPFIEWMLLRLRDYGIRDVILAVQYLADRFRTALGDGSRLGMNVHIVEEP
EPRGTAGAVKHVEHMLDGTTFVFNGDVMTDLDLQAMLDFHRERGSKVTISLTPVDDPTQFGLVETERDGRVRRFLEKPRA
EDITTNLVNAGTYLIEPEIFRYVPPNQFYMFERGLFPVVLQTGDPMYGFPSRAYWTDIGKPQTYLDVHHDILIGKVQYHF
RGQQIGERVWLEGEAEIHSSAQIVGPVVIGHGTRIGRGTRIIGPTVIGSRCTIGPECQIEGVVMWDGNTIEEGSTLRNCV
LGYNNRIGERSHIIDGTIISDECQIGQENRLERGIRIWPGTTLGDRAVSF

Sequences:

>Translated_370_residues
MKAVILVGGQGSRLRPLTCRTPKPMLPLVNQPFIEWMLLRLRDYGIRDVILAVQYLADRFRTALGDGSRLGMNVHIVEEP
EPRGTAGAVKHVEHMLDGTTFVFNGDVMTDLDLQAMLDFHRERGSKVTISLTPVDDPTQFGLVETERDGRVRRFLEKPRA
EDITTNLVNAGTYLIEPEIFRYVPPNQFYMFERGLFPVVLQTGDPMYGFPSRAYWTDIGKPQTYLDVHHDILIGKVQYHF
RGQQIGERVWLEGEAEIHSSAQIVGPVVIGHGTRIGRGTRIIGPTVIGSRCTIGPECQIEGVVMWDGNTIEEGSTLRNCV
LGYNNRIGERSHIIDGTIISDECQIGQENRLERGIRIWPGTTLGDRAVSF
>Mature_370_residues
MKAVILVGGQGSRLRPLTCRTPKPMLPLVNQPFIEWMLLRLRDYGIRDVILAVQYLADRFRTALGDGSRLGMNVHIVEEP
EPRGTAGAVKHVEHMLDGTTFVFNGDVMTDLDLQAMLDFHRERGSKVTISLTPVDDPTQFGLVETERDGRVRRFLEKPRA
EDITTNLVNAGTYLIEPEIFRYVPPNQFYMFERGLFPVVLQTGDPMYGFPSRAYWTDIGKPQTYLDVHHDILIGKVQYHF
RGQQIGERVWLEGEAEIHSSAQIVGPVVIGHGTRIGRGTRIIGPTVIGSRCTIGPECQIEGVVMWDGNTIEEGSTLRNCV
LGYNNRIGERSHIIDGTIISDECQIGQENRLERGIRIWPGTTLGDRAVSF

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=383, Percent_Identity=32.8981723237598, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI11761619, Length=362, Percent_Identity=32.3204419889503, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI31881779, Length=372, Percent_Identity=23.3870967741935, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI45447090, Length=372, Percent_Identity=23.3870967741935, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1788351, Length=238, Percent_Identity=27.7310924369748, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790224, Length=264, Percent_Identity=27.6515151515151, Blast_Score=85, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI133931050, Length=375, Percent_Identity=30.9333333333333, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17509979, Length=324, Percent_Identity=29.0123456790123, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17509981, Length=313, Percent_Identity=27.4760383386581, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320148, Length=373, Percent_Identity=29.7587131367292, Blast_Score=171, Evalue=1e-43,
Organism=Drosophila melanogaster, GI21355443, Length=365, Percent_Identity=31.5068493150685, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24644084, Length=365, Percent_Identity=31.5068493150685, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24653912, Length=374, Percent_Identity=25.4010695187166, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 41567; Mature: 41567

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVILVGGQGSRLRPLTCRTPKPMLPLVNQPFIEWMLLRLRDYGIRDVILAVQYLADRF
CEEEEEECCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RTALGDGSRLGMNVHIVEEPEPRGTAGAVKHVEHMLDGTTFVFNGDVMTDLDLQAMLDFH
HHHHCCCCEECEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEECCCEEECCCHHHHHHHH
RERGSKVTISLTPVDDPTQFGLVETERDGRVRRFLEKPRAEDITTNLVNAGTYLIEPEIF
HCCCCEEEEEEECCCCCCCCCEEEECCCCHHHHHHHCCCCCHHHHHHHHCCEEEECCHHE
RYVPPNQFYMFERGLFPVVLQTGDPMYGFPSRAYWTDIGKPQTYLDVHHDILIGKVQYHF
EECCCCCEEEEECCCEEEEEECCCCCCCCCCCCEECCCCCCCCEEEECCEEEEEEEEEEE
RGQQIGERVWLEGEAEIHSSAQIVGPVVIGHGTRIGRGTRIIGPTVIGSRCTIGPECQIE
CCHHHCCEEEECCCCCCCCCCEEEEEEEEECCCCCCCCCEEECCCEECCCCCCCCCCEEE
GVVMWDGNTIEEGSTLRNCVLGYNNRIGERSHIIDGTIISDECQIGQENRLERGIRIWPG
EEEEECCCCCCCCCHHHHHHHCCCCCCCCCCEEECCEEECCCCCCCCHHHHHCCCEECCC
TTLGDRAVSF
CCCCCCCCCC
>Mature Secondary Structure
MKAVILVGGQGSRLRPLTCRTPKPMLPLVNQPFIEWMLLRLRDYGIRDVILAVQYLADRF
CEEEEEECCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RTALGDGSRLGMNVHIVEEPEPRGTAGAVKHVEHMLDGTTFVFNGDVMTDLDLQAMLDFH
HHHHCCCCEECEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEECCCEEECCCHHHHHHHH
RERGSKVTISLTPVDDPTQFGLVETERDGRVRRFLEKPRAEDITTNLVNAGTYLIEPEIF
HCCCCEEEEEEECCCCCCCCCEEEECCCCHHHHHHHCCCCCHHHHHHHHCCEEEECCHHE
RYVPPNQFYMFERGLFPVVLQTGDPMYGFPSRAYWTDIGKPQTYLDVHHDILIGKVQYHF
EECCCCCEEEEECCCEEEEEECCCCCCCCCCCCEECCCCCCCCEEEECCEEEEEEEEEEE
RGQQIGERVWLEGEAEIHSSAQIVGPVVIGHGTRIGRGTRIIGPTVIGSRCTIGPECQIE
CCHHHCCEEEECCCCCCCCCCEEEEEEEEECCCCCCCCCEEECCCEECCCCCCCCCCEEE
GVVMWDGNTIEEGSTLRNCVLGYNNRIGERSHIIDGTIISDECQIGQENRLERGIRIWPG
EEEEECCCCCCCCCHHHHHHHCCCCCCCCCCEEECCEEECCCCCCCCHHHHHCCCEECCC
TTLGDRAVSF
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]