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The map label for this gene is ycgE [H]

Identifier: 222526145

GI number: 222526145

Start: 3586149

End: 3587096

Strand: Reverse

Name: ycgE [H]

Synonym: Chy400_2902

Alternate gene names: 222526145

Gene position: 3587096-3586149 (Counterclockwise)

Preceding gene: 222526148

Following gene: 222526144

Centisome position: 68.08

GC content: 55.59

Gene sequence:

>948_bases
ATGGCACCGCAGCATTTTCTCTCCCAATTTTCAGACAAGCCACGCTACAATACCAAGGCTGTCGCACAGGAGACGGGCGT
GCCTGCCGACACTTTCCGCGCCTGGGAACGCCGTTACGGTGTACCGCGTCCACAGCGGACGGAAGGTGGTCATCGCCTGT
ATTCCGAGCGCGACATTGCAACGATTCGCTGGCTGCGTGATCGAACCGCCGAAGGACTGACGATCAGTCAGGCGATTGCC
CTGATGATCGAAGGAAGCGACACCAGTCTTTCGTGGCTGAATACCGCAGTTGATACCGAACCGCATACCTGGGAACGGAT
GCAGGCACGCATGATCGCTGCCTTAACCGATTTTGATGCGACACGGGCCGAGCAAATTCTGGGTGAAGCATTTGCGCTCT
ATCCGCTGGAAGATGTCTTTTTGAAATTGATCCAGCCGGCAATGGTTGAAATCGGTGAGCAGTGGCATGCCGGGCGGCTT
TCCGTAACCGCAGAGCATTTTGCTACCCAGTTCATTCGGCGCAAGTTATCAAGCCTGTTCAATACCTATAACGTTACCGA
GGGTCGGGGGCTGGTTGTGGTAGGGTGTGCGCCAAGCGAACAACACGATCTTGGTGCCCTGATGCTGGCCGTCTTTCTGG
TGCGCCACGGCTGGCAGGTGATCTACCTCGGCCCGGAAGTGCCGGTAAAAGACCTTCTTGATGCGGTGCAGCATATCCAA
CCCGACCTGGTGTGTCTGTCTGCTTCAACGACCGAAACGGCCACCCAATTACTCGAAATTGGTCGGGCATTGCAACAGTT
ACCACCGCCTACTCCTCTCTTCGGCTATGGTGGTCGTGCATTCAATTTGAATCCGGTGTTGACACATAAGATGCCGGGCA
CATTTTTGGGGCGTGACGCACAGGAAGCAGTTGAGAACGTCGCATCACTCCTGAGTCGCAGTCGCTAA

Upstream 100 bases:

>100_bases
TGCAATCGTTTCCGTGAATGATGGTACAATAGGATTCAAGTGTAAAAACTATGCGCAATAGTCTCGTCTTTGCATAAGCG
CTGGGAAGGGTCGCGGAACC

Downstream 100 bases:

>100_bases
TGGTGCAGGTACATCGCCGGCATTATCACCATGTCCTGGCTGATAATGCGTAACTCAGTATTGCCTTCAAGCTCAATATT
GCGTATAGTAAAAACAAGCG

Product: regulatory protein MerR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MAPQHFLSQFSDKPRYNTKAVAQETGVPADTFRAWERRYGVPRPQRTEGGHRLYSERDIATIRWLRDRTAEGLTISQAIA
LMIEGSDTSLSWLNTAVDTEPHTWERMQARMIAALTDFDATRAEQILGEAFALYPLEDVFLKLIQPAMVEIGEQWHAGRL
SVTAEHFATQFIRRKLSSLFNTYNVTEGRGLVVVGCAPSEQHDLGALMLAVFLVRHGWQVIYLGPEVPVKDLLDAVQHIQ
PDLVCLSASTTETATQLLEIGRALQQLPPPTPLFGYGGRAFNLNPVLTHKMPGTFLGRDAQEAVENVASLLSRSR

Sequences:

>Translated_315_residues
MAPQHFLSQFSDKPRYNTKAVAQETGVPADTFRAWERRYGVPRPQRTEGGHRLYSERDIATIRWLRDRTAEGLTISQAIA
LMIEGSDTSLSWLNTAVDTEPHTWERMQARMIAALTDFDATRAEQILGEAFALYPLEDVFLKLIQPAMVEIGEQWHAGRL
SVTAEHFATQFIRRKLSSLFNTYNVTEGRGLVVVGCAPSEQHDLGALMLAVFLVRHGWQVIYLGPEVPVKDLLDAVQHIQ
PDLVCLSASTTETATQLLEIGRALQQLPPPTPLFGYGGRAFNLNPVLTHKMPGTFLGRDAQEAVENVASLLSRSR
>Mature_314_residues
APQHFLSQFSDKPRYNTKAVAQETGVPADTFRAWERRYGVPRPQRTEGGHRLYSERDIATIRWLRDRTAEGLTISQAIAL
MIEGSDTSLSWLNTAVDTEPHTWERMQARMIAALTDFDATRAEQILGEAFALYPLEDVFLKLIQPAMVEIGEQWHAGRLS
VTAEHFATQFIRRKLSSLFNTYNVTEGRGLVVVGCAPSEQHDLGALMLAVFLVRHGWQVIYLGPEVPVKDLLDAVQHIQP
DLVCLSASTTETATQLLEIGRALQQLPPPTPLFGYGGRAFNLNPVLTHKMPGTFLGRDAQEAVENVASLLSRSR

Specific function: Controls the expression of 6 small proteins that may play a role in biofilm maturation. Binds to and represses the operator of the ycgZ-ymgA-ariR-ymgC operon, it also regulates yliL and ynaK. Binding is antagonized by YcgF upon blue-light (470 nm) irradia

COG id: COG5012

COG function: function code R; Predicted cobalamin binding protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787409, Length=100, Percent_Identity=37, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551 [H]

Pfam domain/function: PF00376 MerR [H]

EC number: NA

Molecular weight: Translated: 35163; Mature: 35031

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPQHFLSQFSDKPRYNTKAVAQETGVPADTFRAWERRYGVPRPQRTEGGHRLYSERDIA
CCHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHH
TIRWLRDRTAEGLTISQAIALMIEGSDTSLSWLNTAVDTEPHTWERMQARMIAALTDFDA
HHHHHHHHCCCCCCHHHEEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCH
TRAEQILGEAFALYPLEDVFLKLIQPAMVEIGEQWHAGRLSVTAEHFATQFIRRKLSSLF
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHH
NTYNVTEGRGLVVVGCAPSEQHDLGALMLAVFLVRHGWQVIYLGPEVPVKDLLDAVQHIQ
HHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCC
PDLVCLSASTTETATQLLEIGRALQQLPPPTPLFGYGGRAFNLNPVLTHKMPGTFLGRDA
CCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEECCCCCCCCCCCH
QEAVENVASLLSRSR
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
APQHFLSQFSDKPRYNTKAVAQETGVPADTFRAWERRYGVPRPQRTEGGHRLYSERDIA
CHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHH
TIRWLRDRTAEGLTISQAIALMIEGSDTSLSWLNTAVDTEPHTWERMQARMIAALTDFDA
HHHHHHHHCCCCCCHHHEEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCH
TRAEQILGEAFALYPLEDVFLKLIQPAMVEIGEQWHAGRLSVTAEHFATQFIRRKLSSLF
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHH
NTYNVTEGRGLVVVGCAPSEQHDLGALMLAVFLVRHGWQVIYLGPEVPVKDLLDAVQHIQ
HHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCC
PDLVCLSASTTETATQLLEIGRALQQLPPPTPLFGYGGRAFNLNPVLTHKMPGTFLGRDA
CCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEECCCCCCCCCCCH
QEAVENVASLLSRSR
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]