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The map label for this gene is cobO [H]

Identifier: 222526032

GI number: 222526032

Start: 3435446

End: 3436054

Strand: Reverse

Name: cobO [H]

Synonym: Chy400_2789

Alternate gene names: 222526032

Gene position: 3436054-3435446 (Counterclockwise)

Preceding gene: 222526033

Following gene: 222526031

Centisome position: 65.21

GC content: 55.67

Gene sequence:

>609_bases
GTGTCTGATGAGACAACCACACCGGTTGGGCCGGGTTCGTCGCCAGAAGCTGAAGCCCGTCGTAAAGCAGTGCGCGCCAG
TCATACACCGAAGGGCCTGGTGATTGTTAATACCGGCAATGGTAAAGGAAAAACTACTGCCGCGCTCGGTGTCTTGTTGC
GCGCCTGGGGGCGCAATATGCGTGTCGGTGGTGTGCAGTTTATCAAGCACGAGCAGGCGAAATTCGGTGAATTACGCGCG
CTTGAACGGATGGGAATTACCCTGACCCCGCTCGGCGATGGGTTTACCTGGACGAGTCGCGATCTTGATGAGACGCAGGC
ACGAGCAGTACACGGTTGGGAGGTCGCTAAAACGCAGATTATCAGTGGCAATTACGATGTCTTTCTCCTCGATGAGTTTA
CGTATGTGATGCACTACGGCTGGGTACCTGCCACTGAGGTGGTGGCATGGCTGCGCGCAAATAAACCGCCGATGCTGCAC
CTGATCATTACTGGTCGTTACGCACCCGCCGAGCTGATTGAATACGCTGACCTGGTGACTGAAATGCGGGAGGTGAAGCA
TCCGTTCCGTGATCAGGGGATTCGGGCGCAACCGGGTATTGAGTATTGA

Upstream 100 bases:

>100_bases
AACGAGACCTGCATGCTTTGTACTTGCAGTGTTGTCGTTTCATTACCCCGACCCGAGAAGGTCGGGGTTTTTGTTTATAT
GTCAACAGAAGGAGACTGCC

Downstream 100 bases:

>100_bases
GCGAGCAGAACGATGGCTGAACAACTCAAGCGCAATATGGTGCAGCGCCTTGATGGGCGGATGGTAAATGCCGGCGCACG
ACGCGGGATGTTGATTGTCT

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MSDETTTPVGPGSSPEAEARRKAVRASHTPKGLVIVNTGNGKGKTTAALGVLLRAWGRNMRVGGVQFIKHEQAKFGELRA
LERMGITLTPLGDGFTWTSRDLDETQARAVHGWEVAKTQIISGNYDVFLLDEFTYVMHYGWVPATEVVAWLRANKPPMLH
LIITGRYAPAELIEYADLVTEMREVKHPFRDQGIRAQPGIEY

Sequences:

>Translated_202_residues
MSDETTTPVGPGSSPEAEARRKAVRASHTPKGLVIVNTGNGKGKTTAALGVLLRAWGRNMRVGGVQFIKHEQAKFGELRA
LERMGITLTPLGDGFTWTSRDLDETQARAVHGWEVAKTQIISGNYDVFLLDEFTYVMHYGWVPATEVVAWLRANKPPMLH
LIITGRYAPAELIEYADLVTEMREVKHPFRDQGIRAQPGIEY
>Mature_201_residues
SDETTTPVGPGSSPEAEARRKAVRASHTPKGLVIVNTGNGKGKTTAALGVLLRAWGRNMRVGGVQFIKHEQAKFGELRAL
ERMGITLTPLGDGFTWTSRDLDETQARAVHGWEVAKTQIISGNYDVFLLDEFTYVMHYGWVPATEVVAWLRANKPPMLHL
IITGRYAPAELIEYADLVTEMREVKHPFRDQGIRAQPGIEY

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=202, Percent_Identity=40.0990099009901, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22444; Mature: 22313

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDETTTPVGPGSSPEAEARRKAVRASHTPKGLVIVNTGNGKGKTTAALGVLLRAWGRNM
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
RVGGVQFIKHEQAKFGELRALERMGITLTPLGDGFTWTSRDLDETQARAVHGWEVAKTQI
EECCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHCCHHHHEEEE
ISGNYDVFLLDEFTYVMHYGWVPATEVVAWLRANKPPMLHLIITGRYAPAELIEYADLVT
ECCCCCEEEECCCEEEHHCCCCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHH
EMREVKHPFRDQGIRAQPGIEY
HHHHHHCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
SDETTTPVGPGSSPEAEARRKAVRASHTPKGLVIVNTGNGKGKTTAALGVLLRAWGRNM
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
RVGGVQFIKHEQAKFGELRALERMGITLTPLGDGFTWTSRDLDETQARAVHGWEVAKTQI
EECCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHCCHHHHEEEE
ISGNYDVFLLDEFTYVMHYGWVPATEVVAWLRANKPPMLHLIITGRYAPAELIEYADLVT
ECCCCCEEEECCCEEEHHCCCCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHH
EMREVKHPFRDQGIRAQPGIEY
HHHHHHCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1917862 [H]