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The map label for this gene is cobT

Identifier: 222526030

GI number: 222526030

Start: 3430086

End: 3431141

Strand: Reverse

Name: cobT

Synonym: Chy400_2787

Alternate gene names: 222526030

Gene position: 3431141-3430086 (Counterclockwise)

Preceding gene: 222526031

Following gene: 222526029

Centisome position: 65.12

GC content: 63.64

Gene sequence:

>1056_bases
ATGGACCTGGTACAAAGCACCATCAACCAGATCGGCCCCCTCGATGATCGGGCAGCGACGGCTGCACGCCGTCGGCAAGA
CATGCTCACCAAACCGGCAGGATCGCTGGGGCGATTGGAAGAGCTATCAATCCGTATCGCGGGTATTACCGGTCGTGAAC
GGCCACGCCTGACCAATCCGGCAGTCATCGTGATGGCTGCCGATCACGGCGTAGCCCGCCAGGGTGTGAGCGCATTTCCG
GCTGAGGTCACGCCCCAGATGGTCTTGAACTTTCTGCGCGGTGGGGCGGCGATCAACGTCCTGGCCCGCCATGTCGGAGC
ACGGGTAATCGTCGTTGATATTGGCGTAGCGACCGATCTGCCTCCACATCCCGACCTGGTCAGTCGCAAGCTGGCGTATG
GCACTGCCGATTTCAGCCAGGAACCGGCGATGAGCCACGAAACCGCCCGGCAAGCCATTGCCGTTGGGATTGCCTGCGCG
AACCAGGCTATCGATAGCGGCGTTGATCTGCTGGCGACCGGCGAGATGGGCATCGCCAACACCACCGCTGCCAGTGCGGT
GGTTGCTGCCATCACCCGCCGCCCGGCGAGTGAGGTCACCGGACGCGGCACCGGCATTGATGACAGTGGGCTGGCGCGAA
AGATAGCTGTTATCGAACAGGCGTTGCATCGCCACCAGCCCAATCCAGACGACGGGCTTGATGTGCTGGCGAAGGTGGGT
GGCCTCGAGATCGGCGGCCTGGCCGGCGTGATTCTAGGGGCGGCGGCCCGGCGGGTGCCGGTGGTCATCGACGGCTTCAT
CGCCGGCGCGGCAGCGTTGATCGCGGCAACGCTGGCACCGGCAGCCACTGCCTACATGATCGCCGGTCACCGTTCGGTTG
AGCGTGGACATGCGGCGGTCTTTTCGCACCTCGATCTCCAACCCTTGCTCGACCTCAACATGCGGCTCGGTGAGGGTACC
GGTGCTGTGCTGGCGATGTCGATCTGTCAGGCGGCCTGCAAGATTCTCGACGAAATGGCCACCTTCGCTGAAGCCGGTGT
GTCTGAGAAGGTCTGA

Upstream 100 bases:

>100_bases
AGGTTCTGGCACAGGGGGAGGAGTTACGTGAAGGGTTTTCAGCTCCTCGCGACATTGATCGCGAAGGGTAGGGTACAGAG
CGTAGAGGAAGGAGAGGAAG

Downstream 100 bases:

>100_bases
AGCAAGGAGCACTGCTATGAAACACCGTTGGCTTCTCATCAGTCTCGGCGCAGCCATCCTGATCGTATTCGAGGCTCGAC
CAGCTTACGCGATGCACATT

Product: nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MDLVQSTINQIGPLDDRAATAARRRQDMLTKPAGSLGRLEELSIRIAGITGRERPRLTNPAVIVMAADHGVARQGVSAFP
AEVTPQMVLNFLRGGAAINVLARHVGARVIVVDIGVATDLPPHPDLVSRKLAYGTADFSQEPAMSHETARQAIAVGIACA
NQAIDSGVDLLATGEMGIANTTAASAVVAAITRRPASEVTGRGTGIDDSGLARKIAVIEQALHRHQPNPDDGLDVLAKVG
GLEIGGLAGVILGAAARRVPVVIDGFIAGAAALIAATLAPAATAYMIAGHRSVERGHAAVFSHLDLQPLLDLNMRLGEGT
GAVLAMSICQAACKILDEMATFAEAGVSEKV

Sequences:

>Translated_351_residues
MDLVQSTINQIGPLDDRAATAARRRQDMLTKPAGSLGRLEELSIRIAGITGRERPRLTNPAVIVMAADHGVARQGVSAFP
AEVTPQMVLNFLRGGAAINVLARHVGARVIVVDIGVATDLPPHPDLVSRKLAYGTADFSQEPAMSHETARQAIAVGIACA
NQAIDSGVDLLATGEMGIANTTAASAVVAAITRRPASEVTGRGTGIDDSGLARKIAVIEQALHRHQPNPDDGLDVLAKVG
GLEIGGLAGVILGAAARRVPVVIDGFIAGAAALIAATLAPAATAYMIAGHRSVERGHAAVFSHLDLQPLLDLNMRLGEGT
GAVLAMSICQAACKILDEMATFAEAGVSEKV
>Mature_351_residues
MDLVQSTINQIGPLDDRAATAARRRQDMLTKPAGSLGRLEELSIRIAGITGRERPRLTNPAVIVMAADHGVARQGVSAFP
AEVTPQMVLNFLRGGAAINVLARHVGARVIVVDIGVATDLPPHPDLVSRKLAYGTADFSQEPAMSHETARQAIAVGIACA
NQAIDSGVDLLATGEMGIANTTAASAVVAAITRRPASEVTGRGTGIDDSGLARKIAVIEQALHRHQPNPDDGLDVLAKVG
GLEIGGLAGVILGAAARRVPVVIDGFIAGAAALIAATLAPAATAYMIAGHRSVERGHAAVFSHLDLQPLLDLNMRLGEGT
GAVLAMSICQAACKILDEMATFAEAGVSEKV

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family

Homologues:

Organism=Escherichia coli, GI1788300, Length=349, Percent_Identity=43.8395415472779, Blast_Score=273, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBT_CHLAA (A9WIQ7)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001636173.1
- ProteinModelPortal:   A9WIQ7
- SMR:   A9WIQ7
- GeneID:   5827047
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_2578
- HOGENOM:   HBG634399
- OMA:   RSGERGH
- ProtClustDB:   CLSK973028
- HAMAP:   MF_00230
- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846
- Gene3D:   G3DSA:1.10.1610.10
- TIGRFAMs:   TIGR03160

Pfam domain/function: PF02277 DBI_PRT; SSF52733 NN:DBI_PRT

EC number: =2.4.2.21

Molecular weight: Translated: 36154; Mature: 36154

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: ACT_SITE 318-318

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLVQSTINQIGPLDDRAATAARRRQDMLTKPAGSLGRLEELSIRIAGITGRERPRLTNP
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCC
AVIVMAADHGVARQGVSAFPAEVTPQMVLNFLRGGAAINVLARHVGARVIVVDIGVATDL
EEEEEECCCCHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCEEEEEEECCCCCC
PPHPDLVSRKLAYGTADFSQEPAMSHETARQAIAVGIACANQAIDSGVDLLATGEMGIAN
CCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
TTAASAVVAAITRRPASEVTGRGTGIDDSGLARKIAVIEQALHRHQPNPDDGLDVLAKVG
HHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
GLEIGGLAGVILGAAARRVPVVIDGFIAGAAALIAATLAPAATAYMIAGHRSVERGHAAV
CCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FSHLDLQPLLDLNMRLGEGTGAVLAMSICQAACKILDEMATFAEAGVSEKV
HHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDLVQSTINQIGPLDDRAATAARRRQDMLTKPAGSLGRLEELSIRIAGITGRERPRLTNP
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCC
AVIVMAADHGVARQGVSAFPAEVTPQMVLNFLRGGAAINVLARHVGARVIVVDIGVATDL
EEEEEECCCCHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCEEEEEEECCCCCC
PPHPDLVSRKLAYGTADFSQEPAMSHETARQAIAVGIACANQAIDSGVDLLATGEMGIAN
CCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
TTAASAVVAAITRRPASEVTGRGTGIDDSGLARKIAVIEQALHRHQPNPDDGLDVLAKVG
HHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
GLEIGGLAGVILGAAARRVPVVIDGFIAGAAALIAATLAPAATAYMIAGHRSVERGHAAV
CCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FSHLDLQPLLDLNMRLGEGTGAVLAMSICQAACKILDEMATFAEAGVSEKV
HHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA