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The map label for this gene is cbiC [H]

Identifier: 222526021

GI number: 222526021

Start: 3422533

End: 3423195

Strand: Reverse

Name: cbiC [H]

Synonym: Chy400_2777

Alternate gene names: 222526021

Gene position: 3423195-3422533 (Counterclockwise)

Preceding gene: 222526022

Following gene: 222526020

Centisome position: 64.97

GC content: 60.63

Gene sequence:

>663_bases
ATGAACGACCAATCGCCATTGGTATCGGCAGGAGCCGACATTGCCGCCCGTTCGTTTGCGATTATTCGGGCCGAATTACA
GGCGCGCAACCTGATCATCCCGCAACCGCTCGCGGCAATTGTCGAGCGCATCATTCACACGACTGCCGATTTCGAGTTTG
CCGAACTGACTAGAGCCAGTGCCGGTGCGGTAGAAGCAGGGATCAACGCACTCCGGCGTGGATGCCTGGTGATTACCGAT
GTCCAGATGGTTCGGGCAGGCATCGATCAACGACGCCTGCAACATTTTGGCGGCAGTGTAGCCTGCTTCAACGACAACCA
GGCGGTCATGGAACTGGCCGCGGCTACCGGCCTTACCCGCAGTGCCGCCGCTATGCGCTGGGCACACGAGCAGGGGTATC
TGAACGGCGCGCTGGTCGCGATTGGCAATGCACCGACGGCCCTGTTTGAATTGATCAGCCTCATTGACCAGGGTGCCCGC
CCGGCCATCGTGATCGGTATGCCGGTCGGCTTTGTCAACACGGTTGAAAGCAAAGCCGCGCTGATGAACCGCACCGATGT
GGCCTGGATCGTGACCATGGGGCGCAAGGGTGGCTCACCGGTTGCCACAGCCACCGTGAATGCCCTGCTCCGCCTGGCAA
CCGGTGAAGACAACAGCGCGTAA

Upstream 100 bases:

>100_bases
CCGCAGTTGGCACGATTACTGAAGCCGATCTGATCCAGGCCAGGGCACTGGGGCGACGGGTTGCTGAACTTGCCCTTCAG
TTACGCCGGGGAGCAGCATC

Downstream 100 bases:

>100_bases
CGGAGATCAACTATGGCCGATATGGTTCCGCCACGCAACAAACGAGGGTCGCGTACCGGTTACACCACCGGCAGCAATGC
GGCAGCAGCAGCCAAAGCAG

Product: Precorrin-8X methylmutase CbiC/CobH

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MNDQSPLVSAGADIAARSFAIIRAELQARNLIIPQPLAAIVERIIHTTADFEFAELTRASAGAVEAGINALRRGCLVITD
VQMVRAGIDQRRLQHFGGSVACFNDNQAVMELAAATGLTRSAAAMRWAHEQGYLNGALVAIGNAPTALFELISLIDQGAR
PAIVIGMPVGFVNTVESKAALMNRTDVAWIVTMGRKGGSPVATATVNALLRLATGEDNSA

Sequences:

>Translated_220_residues
MNDQSPLVSAGADIAARSFAIIRAELQARNLIIPQPLAAIVERIIHTTADFEFAELTRASAGAVEAGINALRRGCLVITD
VQMVRAGIDQRRLQHFGGSVACFNDNQAVMELAAATGLTRSAAAMRWAHEQGYLNGALVAIGNAPTALFELISLIDQGAR
PAIVIGMPVGFVNTVESKAALMNRTDVAWIVTMGRKGGSPVATATVNALLRLATGEDNSA
>Mature_220_residues
MNDQSPLVSAGADIAARSFAIIRAELQARNLIIPQPLAAIVERIIHTTADFEFAELTRASAGAVEAGINALRRGCLVITD
VQMVRAGIDQRRLQHFGGSVACFNDNQAVMELAAATGLTRSAAAMRWAHEQGYLNGALVAIGNAPTALFELISLIDQGAR
PAIVIGMPVGFVNTVESKAALMNRTDVAWIVTMGRKGGSPVATATVNALLRLATGEDNSA

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 23105; Mature: 23105

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDQSPLVSAGADIAARSFAIIRAELQARNLIIPQPLAAIVERIIHTTADFEFAELTRAS
CCCCCCCHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHC
AGAVEAGINALRRGCLVITDVQMVRAGIDQRRLQHFGGSVACFNDNQAVMELAAATGLTR
CCHHHHHHHHHHCCCEEEEHHHHHHHCHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCHH
SAAAMRWAHEQGYLNGALVAIGNAPTALFELISLIDQGARPAIVIGMPVGFVNTVESKAA
HHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHH
LMNRTDVAWIVTMGRKGGSPVATATVNALLRLATGEDNSA
HHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNDQSPLVSAGADIAARSFAIIRAELQARNLIIPQPLAAIVERIIHTTADFEFAELTRAS
CCCCCCCHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHC
AGAVEAGINALRRGCLVITDVQMVRAGIDQRRLQHFGGSVACFNDNQAVMELAAATGLTR
CCHHHHHHHHHHCCCEEEEHHHHHHHCHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCHH
SAAAMRWAHEQGYLNGALVAIGNAPTALFELISLIDQGARPAIVIGMPVGFVNTVESKAA
HHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHH
LMNRTDVAWIVTMGRKGGSPVATATVNALLRLATGEDNSA
HHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]