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The map label for this gene is rlmL [H]

Identifier: 222525800

GI number: 222525800

Start: 3205018

End: 3205914

Strand: Direct

Name: rlmL [H]

Synonym: Chy400_2553

Alternate gene names: 222525800

Gene position: 3205018-3205914 (Clockwise)

Preceding gene: 222525799

Following gene: 222525801

Centisome position: 60.83

GC content: 57.75

Gene sequence:

>897_bases
ATGGAGCTGCGCCTGTTAACACCGCCGCGCTGGGCCGATTATGAGCTGCTCGATTCAGGGCACGGTGCCAAGCTGGAGCG
GTTCGGGCCATACGTGTTGGCCAGACCGGAAACACAGGCGATTTGGACGCCCCGCTTGCCGGCGTCCGCGTGGCAGCAGG
CCGATGCAACCTTTCGTCGTTCGCGTGGCGAAGACGGGCCAGGCGAGTGGCATCAACACCATTCCTTGCCCGAACGCTGG
CCACTTGATGCCAATGGGGTTCGTTGCTGGGTTCGTCTGACACCGTTTCGTCATACTGGTGTCTTCCCGGAACATAGTGC
CCATTGGGACTGGCTGGCTCGCCAGGTGCAACGCCGCTCGCAACCGCGAGCACTGGTATTGTTTGGATATACTGGCTTGA
GTAGCCTGCATCTTGCGCGCTGTGGTGCTCACGTTACCCACGTTGATGCTTCTAAGCCCGCAGTGCGTTGGGCACAAGAA
AATCAGGCGCTGGCCGAACTGACGGATCGCCCCATCCGGTGGCTGATCGATGATGTCGGTAAATTTGTTGCCCGTGAATT
GCGGCGTGGTAATCGGTATGATCTGATCTTGCTCGACCCGCCAGTCTTCGGGCGTGGGCCAAACGGTGAAATCTGGCGCT
TACACGAACAATTACCGCATTTGCTGGCCCAATGCGCTCGTTTGCTGAGCCAGCAACCACTCGGAGTGTTAGTGTGCGCC
TATGCAACGACTATTTCAGCGTTGACCATCGGTAATTTGCTTGCAGAGACGATGGCACCGTTTGCCGGTTATGTGAGTGC
TGGTGAGTTGGCAATTCCTGAACAAACAACGCATCGGCTGCTACCAACCGCTATCTACGCCGCCTGGTCTGATCGGGAAA
TAGCCATCTCTGGCTGA

Upstream 100 bases:

>100_bases
CCTGAAGCGTTGGCGAAGGAGATTATCGAGAAGCGTAGTGCGAATTAGTGAGGGGATCGGGGACGGTCGCCCCGTGCGGT
CGTCCCTTTTTTCGACGACG

Downstream 100 bases:

>100_bases
TGATAGGGATTAAGTAGATCGCGCAAGAACGCGGAGGAATCAAACAATGGCCAAGCAGAAATTCGAGCGGACGAAACCGC
ACATTAACGTCGGCACCATC

Product: putative SAM-dependent methyltransferase

Products: NA

Alternate protein names: 23S rRNA m2G2445 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rlmL [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MELRLLTPPRWADYELLDSGHGAKLERFGPYVLARPETQAIWTPRLPASAWQQADATFRRSRGEDGPGEWHQHHSLPERW
PLDANGVRCWVRLTPFRHTGVFPEHSAHWDWLARQVQRRSQPRALVLFGYTGLSSLHLARCGAHVTHVDASKPAVRWAQE
NQALAELTDRPIRWLIDDVGKFVARELRRGNRYDLILLDPPVFGRGPNGEIWRLHEQLPHLLAQCARLLSQQPLGVLVCA
YATTISALTIGNLLAETMAPFAGYVSAGELAIPEQTTHRLLPTAIYAAWSDREIAISG

Sequences:

>Translated_298_residues
MELRLLTPPRWADYELLDSGHGAKLERFGPYVLARPETQAIWTPRLPASAWQQADATFRRSRGEDGPGEWHQHHSLPERW
PLDANGVRCWVRLTPFRHTGVFPEHSAHWDWLARQVQRRSQPRALVLFGYTGLSSLHLARCGAHVTHVDASKPAVRWAQE
NQALAELTDRPIRWLIDDVGKFVARELRRGNRYDLILLDPPVFGRGPNGEIWRLHEQLPHLLAQCARLLSQQPLGVLVCA
YATTISALTIGNLLAETMAPFAGYVSAGELAIPEQTTHRLLPTAIYAAWSDREIAISG
>Mature_298_residues
MELRLLTPPRWADYELLDSGHGAKLERFGPYVLARPETQAIWTPRLPASAWQQADATFRRSRGEDGPGEWHQHHSLPERW
PLDANGVRCWVRLTPFRHTGVFPEHSAHWDWLARQVQRRSQPRALVLFGYTGLSSLHLARCGAHVTHVDASKPAVRWAQE
NQALAELTDRPIRWLIDDVGKFVARELRRGNRYDLILLDPPVFGRGPNGEIWRLHEQLPHLLAQCARLLSQQPLGVLVCA
YATTISALTIGNLLAETMAPFAGYVSAGELAIPEQTTHRLLPTAIYAAWSDREIAISG

Specific function: Specifically methylates the guanosine in position 2445 (m2G2445) of 23S rRNA [H]

COG id: COG1092

COG function: function code R; Predicted SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 THUMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR000241
- InterPro:   IPR017244
- InterPro:   IPR019614
- InterPro:   IPR004114 [H]

Pfam domain/function: PF10672 Methyltrans_SAM; PF02926 THUMP; PF01170 UPF0020 [H]

EC number: =2.1.1.173 [H]

Molecular weight: Translated: 33620; Mature: 33620

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRLLTPPRWADYELLDSGHGAKLERFGPYVLARPETQAIWTPRLPASAWQQADATFRR
CCEEECCCCCCCCHHHHCCCCCCCHHHCCCEEEECCCCCEEECCCCCHHHHHHHHHHHHH
SRGEDGPGEWHQHHSLPERWPLDANGVRCWVRLTPFRHTGVFPEHSAHWDWLARQVQRRS
HCCCCCCCCHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCC
QPRALVLFGYTGLSSLHLARCGAHVTHVDASKPAVRWAQENQALAELTDRPIRWLIDDVG
CCCEEEEEECCCCHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHH
KFVARELRRGNRYDLILLDPPVFGRGPNGEIWRLHEQLPHLLAQCARLLSQQPLGVLVCA
HHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCEEHHH
YATTISALTIGNLLAETMAPFAGYVSAGELAIPEQTTHRLLPTAIYAAWSDREIAISG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure
MELRLLTPPRWADYELLDSGHGAKLERFGPYVLARPETQAIWTPRLPASAWQQADATFRR
CCEEECCCCCCCCHHHHCCCCCCCHHHCCCEEEECCCCCEEECCCCCHHHHHHHHHHHHH
SRGEDGPGEWHQHHSLPERWPLDANGVRCWVRLTPFRHTGVFPEHSAHWDWLARQVQRRS
HCCCCCCCCHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCC
QPRALVLFGYTGLSSLHLARCGAHVTHVDASKPAVRWAQENQALAELTDRPIRWLIDDVG
CCCEEEEEECCCCHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHH
KFVARELRRGNRYDLILLDPPVFGRGPNGEIWRLHEQLPHLLAQCARLLSQQPLGVLVCA
HHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCEEHHH
YATTISALTIGNLLAETMAPFAGYVSAGELAIPEQTTHRLLPTAIYAAWSDREIAISG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA