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The map label for this gene is rcsC [H]

Identifier: 222525754

GI number: 222525754

Start: 3148514

End: 3148909

Strand: Reverse

Name: rcsC [H]

Synonym: Chy400_2507

Alternate gene names: 222525754

Gene position: 3148909-3148514 (Counterclockwise)

Preceding gene: 222525757

Following gene: 222525753

Centisome position: 59.76

GC content: 51.26

Gene sequence:

>396_bases
ATGTCCGATTTTTCCGGTCGCAATCCGGCAATCATTCTAGTCGAGGATGAGCCTGATATTCTCATCATCTTGCATCGCTT
GATGCGAGATTTGACCGGGGGATACGATATTATTACCGTCAACAGCGGTGCTGACGCGCTTGCCCAGATTGCGCTCAGGA
AAGTGCCGCTCGTCATCACCGATTACAATATGCCAGGTATGAATGGCTTGCAGCTTGCGGCTGCGATCAAGGAGACTTCG
CCTGATACCTGTGTGGTGATGATTACAGCCTATGCGACGCCTGAGCTAGAACGACGCGCTCGCGAGCAACGTATCGATTA
TTATTTGTCTAAGCCTTTCCCGCTGGATCGCCTCGAACAAATCGTGCGTGATGTACTGCGCTCATACATCAGCTAG

Upstream 100 bases:

>100_bases
CCGTCATGCAGGGCTGTGATACAATACCGCCATATTCGCCAGTTGCGGGGTGGATTGTTTACAGGTAACAGGGCTTGTGG
GAGGTTAAGGAGTTTCTCCT

Downstream 100 bases:

>100_bases
ACATCAGATCGCTGTCATTCTCTCTGCGTAGCCTCCTCGTTACGATGATGACGCCTGCCATTCAAGCGTTACCATTTCAG
ACGGAGGCACGTCATGAACG

Product: response regulator receiver protein

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 131; Mature: 130

Protein sequence:

>131_residues
MSDFSGRNPAIILVEDEPDILIILHRLMRDLTGGYDIITVNSGADALAQIALRKVPLVITDYNMPGMNGLQLAAAIKETS
PDTCVVMITAYATPELERRAREQRIDYYLSKPFPLDRLEQIVRDVLRSYIS

Sequences:

>Translated_131_residues
MSDFSGRNPAIILVEDEPDILIILHRLMRDLTGGYDIITVNSGADALAQIALRKVPLVITDYNMPGMNGLQLAAAIKETS
PDTCVVMITAYATPELERRAREQRIDYYLSKPFPLDRLEQIVRDVLRSYIS
>Mature_130_residues
SDFSGRNPAIILVEDEPDILIILHRLMRDLTGGYDIITVNSGADALAQIALRKVPLVITDYNMPGMNGLQLAAAIKETSP
DTCVVMITAYATPELERRAREQRIDYYLSKPFPLDRLEQIVRDVLRSYIS

Specific function: Member of the two-component regulatory system rcsC/rcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with rcsF, rcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=114, Percent_Identity=35.9649122807018, Blast_Score=66, Evalue=6e-13,
Organism=Escherichia coli, GI1788905, Length=116, Percent_Identity=35.3448275862069, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 14722; Mature: 14591

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFSGRNPAIILVEDEPDILIILHRLMRDLTGGYDIITVNSGADALAQIALRKVPLVIT
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCEEEE
DYNMPGMNGLQLAAAIKETSPDTCVVMITAYATPELERRAREQRIDYYLSKPFPLDRLEQ
ECCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHH
IVRDVLRSYIS
HHHHHHHHHCC
>Mature Secondary Structure 
SDFSGRNPAIILVEDEPDILIILHRLMRDLTGGYDIITVNSGADALAQIALRKVPLVIT
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCEEEE
DYNMPGMNGLQLAAAIKETSPDTCVVMITAYATPELERRAREQRIDYYLSKPFPLDRLEQ
ECCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHH
IVRDVLRSYIS
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504; 8626298 [H]