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The map label for this gene is hepT [H]

Identifier: 222525750

GI number: 222525750

Start: 3142190

End: 3143107

Strand: Reverse

Name: hepT [H]

Synonym: Chy400_2501

Alternate gene names: 222525750

Gene position: 3143107-3142190 (Counterclockwise)

Preceding gene: 222525753

Following gene: 222525749

Centisome position: 59.65

GC content: 57.19

Gene sequence:

>918_bases
ATGACCTTCGCTATCCCATCAGAATTGCATCACGATCTGTTGCGGGTTGAGCAGATTCTTCAAGAGCGGATGCGAGCGCG
CTATAGCGTTATTGCAATGGTTAATCCACACGTAGTTACTGACGCAACAGATCGGTTGCGGGCACTCGTTGTGCTGGCGG
TTGCCCGGTTGGGCAACTACACCGATGCACAGGTAGTCCATGCGGCTGCTGCCGTTGAATTGATTGAAGCAGCAACCCGT
GCGCATGACACCTTGATTGATGAACACGCCCGACGGACAGGTCGCGGAGCGAACGGATCGTGGGATCATGGTGTCGTCCT
GATGATAGGTGACTACCTCTTTGCCCTGGCTGCCGGCGAAATGGCACGCAGCCCTGATCCACGGATTATCAGTCTCTATT
CACAGGCAGTCATGCAGGTTTGTGAAGGGCAGTTGATCACCATTACCAGCCTGACCCCGCCGGAAACAGCCCTGGCCACC
TACTGGCAGCGCACTGAAGCGCTCTCAGGGGCATTACTGGCAGCAGCAGCCCAGGCCGGAATACTATGTGGCAATCTCCC
GGATACGTTGCTTGAGCCAGCAGCACGGTTTGGTATGCATCTGGGGCTGGCGCGGCGTCTGGCGACCGAAATTCGCGATC
TGGAAGCGGAAGGCAGACTGTTACAGGCGGGTAATATTCCGCTGGCGCTCCTGTTTGCGGCCACCGAACCGCTGGCCCCA
GAAGTACAAGCGGTATTTGATCATCCCACTCCAGCAACGATTGCCGCCGTCTTACCGCTGATTCGCAACCACGGGCTACC
GAAGGCACGTGCCGCACTTATTGAACAACAACACGCAGCCCGGCAGGCGCTCCAACAGTTGCCTGCCGGCAGCACAACTG
CCTGGTTGAACCAATTGATCGATGAGACTGGCGCATAA

Upstream 100 bases:

>100_bases
AGACGGGGAGCGTCGCTGCACCAGTCGCGGTTGACAGTGGTACAGGGATAGCGTATCTTTCCTAGTAATGGGCGATAAAA
CATAGCTAAAGTGACAGACC

Downstream 100 bases:

>100_bases
GAGACCTGAATGCCTGTGTTATAATGCGACGGCTAAGCAAGCAATGCTGCTTTCAATTCGGCAGGAGTGTCTATGTACCG
TTCACATACCTGTGGTGAGT

Product: polyprenyl synthetase

Products: NA

Alternate protein names: HEPPP synthase subunit 2 [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MTFAIPSELHHDLLRVEQILQERMRARYSVIAMVNPHVVTDATDRLRALVVLAVARLGNYTDAQVVHAAAAVELIEAATR
AHDTLIDEHARRTGRGANGSWDHGVVLMIGDYLFALAAGEMARSPDPRIISLYSQAVMQVCEGQLITITSLTPPETALAT
YWQRTEALSGALLAAAAQAGILCGNLPDTLLEPAARFGMHLGLARRLATEIRDLEAEGRLLQAGNIPLALLFAATEPLAP
EVQAVFDHPTPATIAAVLPLIRNHGLPKARAALIEQQHAARQALQQLPAGSTTAWLNQLIDETGA

Sequences:

>Translated_305_residues
MTFAIPSELHHDLLRVEQILQERMRARYSVIAMVNPHVVTDATDRLRALVVLAVARLGNYTDAQVVHAAAAVELIEAATR
AHDTLIDEHARRTGRGANGSWDHGVVLMIGDYLFALAAGEMARSPDPRIISLYSQAVMQVCEGQLITITSLTPPETALAT
YWQRTEALSGALLAAAAQAGILCGNLPDTLLEPAARFGMHLGLARRLATEIRDLEAEGRLLQAGNIPLALLFAATEPLAP
EVQAVFDHPTPATIAAVLPLIRNHGLPKARAALIEQQHAARQALQQLPAGSTTAWLNQLIDETGA
>Mature_304_residues
TFAIPSELHHDLLRVEQILQERMRARYSVIAMVNPHVVTDATDRLRALVVLAVARLGNYTDAQVVHAAAAVELIEAATRA
HDTLIDEHARRTGRGANGSWDHGVVLMIGDYLFALAAGEMARSPDPRIISLYSQAVMQVCEGQLITITSLTPPETALATY
WQRTEALSGALLAAAAQAGILCGNLPDTLLEPAARFGMHLGLARRLATEIRDLEAEGRLLQAGNIPLALLFAATEPLAPE
VQAVFDHPTPATIAAVLPLIRNHGLPKARAALIEQQHAARQALQQLPAGSTTAWLNQLIDETGA

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789578, Length=302, Percent_Identity=24.1721854304636, Blast_Score=84, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24651612, Length=244, Percent_Identity=26.6393442622951, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 32782; Mature: 32651

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFAIPSELHHDLLRVEQILQERMRARYSVIAMVNPHVVTDATDRLRALVVLAVARLGNY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEECCHHHHHHHHHHHHHHHHCCC
TDAQVVHAAAAVELIEAATRAHDTLIDEHARRTGRGANGSWDHGVVLMIGDYLFALAAGE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHH
MARSPDPRIISLYSQAVMQVCEGQLITITSLTPPETALATYWQRTEALSGALLAAAAQAG
HHCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
ILCGNLPDTLLEPAARFGMHLGLARRLATEIRDLEAEGRLLQAGNIPLALLFAATEPLAP
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCH
EVQAVFDHPTPATIAAVLPLIRNHGLPKARAALIEQQHAARQALQQLPAGSTTAWLNQLI
HHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
DETGA
HHCCC
>Mature Secondary Structure 
TFAIPSELHHDLLRVEQILQERMRARYSVIAMVNPHVVTDATDRLRALVVLAVARLGNY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEECCHHHHHHHHHHHHHHHHCCC
TDAQVVHAAAAVELIEAATRAHDTLIDEHARRTGRGANGSWDHGVVLMIGDYLFALAAGE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHH
MARSPDPRIISLYSQAVMQVCEGQLITITSLTPPETALATYWQRTEALSGALLAAAAQAG
HHCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
ILCGNLPDTLLEPAARFGMHLGLARRLATEIRDLEAEGRLLQAGNIPLALLFAATEPLAP
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCH
EVQAVFDHPTPATIAAVLPLIRNHGLPKARAALIEQQHAARQALQQLPAGSTTAWLNQLI
HHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
DETGA
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7629164 [H]