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The map label for this gene is cmpR [H]

Identifier: 222525671

GI number: 222525671

Start: 3052398

End: 3053324

Strand: Direct

Name: cmpR [H]

Synonym: Chy400_2422

Alternate gene names: 222525671

Gene position: 3052398-3053324 (Clockwise)

Preceding gene: 222525670

Following gene: 222525672

Centisome position: 57.93

GC content: 60.09

Gene sequence:

>927_bases
ATGCTGAATACCGTCTACTTGCAAACCTTTCTTGCCGTCGTCGAGACGGGTTCGTTTTCAGCCGCCGCCAAGCGACTGCA
CCTCTCACAACCGGCGGTGAGTCAGCAAATTCGGGCGTTAGAGGAGCAGGTTGGCGGTGTCCGGCTGTTTCGGCGGAGTG
GACAACAGATGGTGCTGACGCTGGCCGGTGAGCAGTTGCTGACCAGCGCCCGTGAAATGGTAGCCCTGGCCGAACGCACG
GTACAGGCGGTCAGTGCGTTGCGCGGTCAGGTTGGTGGGCGGGTGGCGATTGGTTGTCTCGCCGGGGGAGTTGAGGCATT
TCTGCCACATCTGTTGACGATTGTGCAGCGTCAGTATCCGGCGTTGACGGTAGATATCGAGTTGCAGCAGGCTGAGCGTT
TGTTTGAAGGACTGGCCGAGCGGCGCTTTGATCTGGCAATTTTGAGCGATGCACCGCGACGACGTGGTTTCGAGACGCGC
TTACTGGCCGGTGAACGGCTGGCATTGACGGCGGTAATTGGGCATGACCTGTTGCAGCAGGAACAGGTACCAGTCGGTGT
GCTTCGTGACTATCCCCTGGCCCTGCCACGTGTCGGCCATCCGTTGCGCCGTTCTATCGAAGATGGTCTGCGACGGCGTG
GCCTTTCGGTTGGCGAATTGCGTGTTGTCTGTGAAACCGATAGTCCGTTGTTGCTGCGGGCAGCAGTAGAGGCCGGCCAG
GCGCTGGCCTTTTTGCCGGTCAGTGTGCTGCCCACACGTCTGGATCGGCTGGGGGTGGTGGCGTTAGCCGGTCAGCCACT
GGTACAGGAGTGGTATCTAATACGGTTGCGTGAACGAACGACGGCCCGGATTGTTGATCTGTTGGTCGAATGCCTGTTGG
GTGAAGAGGCACGGTCAACGCTCCTGCGCCTGGGCTTGTCGGCGTGA

Upstream 100 bases:

>100_bases
GTGATGGTCGAGTTGCTGAATCTGCGGGTCGCAGCCAGGGCGCGCCAGCCGGTGCAGTTGCATCAACGCTACGACACAAC
CAAACTGAGCCATTGATCGT

Downstream 100 bases:

>100_bases
CGACGAGAGTCTGATCGGCGTGCGTACACGCTCTCGCCAATGAAGGCAGGGCGGGTAGCAGCGGCACAGGCTGTAGCGCC
TGGGGTGCAACCACGGATTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MLNTVYLQTFLAVVETGSFSAAAKRLHLSQPAVSQQIRALEEQVGGVRLFRRSGQQMVLTLAGEQLLTSAREMVALAERT
VQAVSALRGQVGGRVAIGCLAGGVEAFLPHLLTIVQRQYPALTVDIELQQAERLFEGLAERRFDLAILSDAPRRRGFETR
LLAGERLALTAVIGHDLLQQEQVPVGVLRDYPLALPRVGHPLRRSIEDGLRRRGLSVGELRVVCETDSPLLLRAAVEAGQ
ALAFLPVSVLPTRLDRLGVVALAGQPLVQEWYLIRLRERTTARIVDLLVECLLGEEARSTLLRLGLSA

Sequences:

>Translated_308_residues
MLNTVYLQTFLAVVETGSFSAAAKRLHLSQPAVSQQIRALEEQVGGVRLFRRSGQQMVLTLAGEQLLTSAREMVALAERT
VQAVSALRGQVGGRVAIGCLAGGVEAFLPHLLTIVQRQYPALTVDIELQQAERLFEGLAERRFDLAILSDAPRRRGFETR
LLAGERLALTAVIGHDLLQQEQVPVGVLRDYPLALPRVGHPLRRSIEDGLRRRGLSVGELRVVCETDSPLLLRAAVEAGQ
ALAFLPVSVLPTRLDRLGVVALAGQPLVQEWYLIRLRERTTARIVDLLVECLLGEEARSTLLRLGLSA
>Mature_308_residues
MLNTVYLQTFLAVVETGSFSAAAKRLHLSQPAVSQQIRALEEQVGGVRLFRRSGQQMVLTLAGEQLLTSAREMVALAERT
VQAVSALRGQVGGRVAIGCLAGGVEAFLPHLLTIVQRQYPALTVDIELQQAERLFEGLAERRFDLAILSDAPRRRGFETR
LLAGERLALTAVIGHDLLQQEQVPVGVLRDYPLALPRVGHPLRRSIEDGLRRRGLSVGELRVVCETDSPLLLRAAVEAGQ
ALAFLPVSVLPTRLDRLGVVALAGQPLVQEWYLIRLRERTTARIVDLLVECLLGEEARSTLLRLGLSA

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=267, Percent_Identity=31.4606741573034, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787879, Length=276, Percent_Identity=27.8985507246377, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI145693105, Length=263, Percent_Identity=26.615969581749, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788297, Length=248, Percent_Identity=27.8225806451613, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081904, Length=273, Percent_Identity=29.3040293040293, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790399, Length=265, Percent_Identity=27.5471698113208, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI48994962, Length=171, Percent_Identity=35.0877192982456, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1789204, Length=191, Percent_Identity=31.9371727748691, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788748, Length=245, Percent_Identity=26.1224489795918, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1786713, Length=149, Percent_Identity=34.8993288590604, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788626, Length=244, Percent_Identity=27.8688524590164, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787601, Length=302, Percent_Identity=24.8344370860927, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787806, Length=271, Percent_Identity=23.6162361623616, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790262, Length=260, Percent_Identity=27.3076923076923, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI2367136, Length=292, Percent_Identity=27.3972602739726, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33736; Mature: 33736

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTVYLQTFLAVVETGSFSAAAKRLHLSQPAVSQQIRALEEQVGGVRLFRRSGQQMVLT
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHCCCEEEEE
LAGEQLLTSAREMVALAERTVQAVSALRGQVGGRVAIGCLAGGVEAFLPHLLTIVQRQYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCHHHHHHHHHHHHHHCCC
ALTVDIELQQAERLFEGLAERRFDLAILSDAPRRRGFETRLLAGERLALTAVIGHDLLQQ
CEEEEEEHHHHHHHHHHHHHHHHCEEEECCCCHHCCCCHHHHCCCHHHHHHHHHHHHHHH
EQVPVGVLRDYPLALPRVGHPLRRSIEDGLRRRGLSVGELRVVCETDSPLLLRAAVEAGQ
CCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHCC
ALAFLPVSVLPTRLDRLGVVALAGQPLVQEWYLIRLRERTTARIVDLLVECLLGEEARST
EEEHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LLRLGLSA
HHHHCCCC
>Mature Secondary Structure
MLNTVYLQTFLAVVETGSFSAAAKRLHLSQPAVSQQIRALEEQVGGVRLFRRSGQQMVLT
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHCCCEEEEE
LAGEQLLTSAREMVALAERTVQAVSALRGQVGGRVAIGCLAGGVEAFLPHLLTIVQRQYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCHHHHHHHHHHHHHHCCC
ALTVDIELQQAERLFEGLAERRFDLAILSDAPRRRGFETRLLAGERLALTAVIGHDLLQQ
CEEEEEEHHHHHHHHHHHHHHHHCEEEECCCCHHCCCCHHHHCCCHHHHHHHHHHHHHHH
EQVPVGVLRDYPLALPRVGHPLRRSIEDGLRRRGLSVGELRVVCETDSPLLLRAAVEAGQ
CCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHCC
ALAFLPVSVLPTRLDRLGVVALAGQPLVQEWYLIRLRERTTARIVDLLVECLLGEEARST
EEEHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LLRLGLSA
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]