Click here to switch to the map view.

The map label for this gene is sat/cysC [H]

Identifier: 222525529

GI number: 222525529

Start: 2882478

End: 2884187

Strand: Direct

Name: sat/cysC [H]

Synonym: Chy400_2278

Alternate gene names: 222525529

Gene position: 2882478-2884187 (Clockwise)

Preceding gene: 222525528

Following gene: 222525530

Centisome position: 54.71

GC content: 56.61

Gene sequence:

>1710_bases
ATGCCCAATGACAATCTTCTCATTTCACCGTATGGTGGTCGTCTGATTGATCTGTGCGTGTCGGCTGAAGAGCGCGATGA
CGTACTTGCCGAAGCCTCACGTCTGCCTTCGATTCAAATTTCCATGCGCAGTATGTGCGATCTGGAACTGCTGGCTACCG
GTGGCTTTTCACCGCTGACCGGTTTTATGGGGCGGGCAGATTACGAGCGTGTCTTGGAAGAGATGCGGCTGGCGGATGGT
ACCCTCTGGCCAATTCCGGTGACACTGCCGGTTGAAAAGAGCCATTTCGGTAGCGACCGCATCGTCCTGCGCGATGTTCA
TAACAATCCCCTGGCCATTATGGAGATAAGTGACATCTACCGGTGGGATGCCGAACGTGAAGCACTGGCCGTCCTGGGTA
CGACCGATCCACACCATCCGCTGGTGGCCGAAATGGCGCGTTGGGGCAAGTTTTATGCTGCCGGTCGCCTGCGCGTTATC
AATTTGCCCCGCTACTACGACTTTACCGATCTCCGTCGTACCCCGGCTGAAGTGCGGCGTCTGTTACAGGCAATGGGGCG
GCCAAATGTGGTTGCCTTCCAGACGCGCAACCCGATGCATCGCATCCACGAAGAGCTGACCAAGCGGGCCGCAGCGCAAG
TAGATGGCAGCCTGCTGATCCATCCGGTTGTTGGCATGACCAAACCCGGTGATATCGATCACTTTACCCGTGTTCGTAGT
TACCGGTTGCTGGTCGAAAAATACTACGATCCTGGTCGTACTCTACTCAGTCTGTTGCCGTTGGCGATGCGCATGGCCGG
CCCGCGTGAAGCGGTCTGGCACGCCATCATCCGCCGCAATTACGGTGCAAATCATTTCATCGTTGGCCGTGACCATGCCG
GCCCTGGGAACGACAGTACAGGTAAGCCGTTTTATGGGCCGTATGCGGCGCAAGAGCTACTGGCTCATTATGCGCACGAA
ATAGGTGTGACGATGATCCCGTTCACCGAACTGGTGTATCTCAAACGGGAAGGGCGCTATGTCACAATCGACGAGGTGCC
GCCAGGGGCCGAAATTTCCTCTATTTCAGGTACACAGGTGCGAGATGAGTATCTGGCGAAAGGGCGGCTCCTGCCTGAGT
GGTTTACGCGCCCGGAAACTGCCGAGATTCTCCGCCAGATGTATCCACCTCGCCATCGGCAAGGGTTTTGTGTCTGGTTT
ACCGGTCTGAGTGGGGCCGGAAAATCGACCATTGCCGCCATCTTGAATGTGCTCTTGCTGGAACGGGGCCGTACACCAAC
AGTCCTGGATGGTGACGTTGTGCGTACCCACTTGTCGAAAGGGTTGGGTTTCTCGCGGGAAGATCGTGATACCAACATTC
TGCGGATCGGCTTTGTTGCCAGTGCCGTGGTGAAAGCCGGTGGTGCGGTCATCTGTGCGGCGGTCAGCCCTTATCGGGCG
GCGCGCAATGAGTGTCGGACAATGATCGGCAGCGATCAGTTCATCGAGGTGTTTGTTGACACCCCGCTCGAAGTGTGTGA
GCAGCGTGATGTCAAGGGGCTATACGCAAAAGCCCGGCGTGGTGAGCTACGTGGCTTTACCGGCATTGATGATCCGTATG
AACCGCCGGTCAACCCTGAGTTGACCCTGACCACCACGGATGTGACCCCGGAAGAGAATGCGCGCAAGATCATTCGCTAT
CTGGAAGAGAAGGGTTTCCTGGAGGGATAA

Upstream 100 bases:

>100_bases
AACACCGGTGCGGGTGCCCTGGTTTCGTCCGGCGTTGTAATGATTGTGAGGCGCGACCATTGTGGACGCGCCGATTGGTG
TTGTCACGTTAAGGAATCTT

Downstream 100 bases:

>100_bases
ATGAAAGATGTCTTCGCACACGCCCGGCGCACACTACGGCAATGGTTGAAAGGCCCAAACGCCGATTTAGGTTTTAAACC
GCAACCCGATTTTTACTATC

Product: bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein

Products: NA

Alternate protein names: Sulfate adenylyltransferase; ATP-sulfurylase; Sulfate adenylate transferase; SAT; Adenylyl-sulfate kinase; APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MPNDNLLISPYGGRLIDLCVSAEERDDVLAEASRLPSIQISMRSMCDLELLATGGFSPLTGFMGRADYERVLEEMRLADG
TLWPIPVTLPVEKSHFGSDRIVLRDVHNNPLAIMEISDIYRWDAEREALAVLGTTDPHHPLVAEMARWGKFYAAGRLRVI
NLPRYYDFTDLRRTPAEVRRLLQAMGRPNVVAFQTRNPMHRIHEELTKRAAAQVDGSLLIHPVVGMTKPGDIDHFTRVRS
YRLLVEKYYDPGRTLLSLLPLAMRMAGPREAVWHAIIRRNYGANHFIVGRDHAGPGNDSTGKPFYGPYAAQELLAHYAHE
IGVTMIPFTELVYLKREGRYVTIDEVPPGAEISSISGTQVRDEYLAKGRLLPEWFTRPETAEILRQMYPPRHRQGFCVWF
TGLSGAGKSTIAAILNVLLLERGRTPTVLDGDVVRTHLSKGLGFSREDRDTNILRIGFVASAVVKAGGAVICAAVSPYRA
ARNECRTMIGSDQFIEVFVDTPLEVCEQRDVKGLYAKARRGELRGFTGIDDPYEPPVNPELTLTTTDVTPEENARKIIRY
LEEKGFLEG

Sequences:

>Translated_569_residues
MPNDNLLISPYGGRLIDLCVSAEERDDVLAEASRLPSIQISMRSMCDLELLATGGFSPLTGFMGRADYERVLEEMRLADG
TLWPIPVTLPVEKSHFGSDRIVLRDVHNNPLAIMEISDIYRWDAEREALAVLGTTDPHHPLVAEMARWGKFYAAGRLRVI
NLPRYYDFTDLRRTPAEVRRLLQAMGRPNVVAFQTRNPMHRIHEELTKRAAAQVDGSLLIHPVVGMTKPGDIDHFTRVRS
YRLLVEKYYDPGRTLLSLLPLAMRMAGPREAVWHAIIRRNYGANHFIVGRDHAGPGNDSTGKPFYGPYAAQELLAHYAHE
IGVTMIPFTELVYLKREGRYVTIDEVPPGAEISSISGTQVRDEYLAKGRLLPEWFTRPETAEILRQMYPPRHRQGFCVWF
TGLSGAGKSTIAAILNVLLLERGRTPTVLDGDVVRTHLSKGLGFSREDRDTNILRIGFVASAVVKAGGAVICAAVSPYRA
ARNECRTMIGSDQFIEVFVDTPLEVCEQRDVKGLYAKARRGELRGFTGIDDPYEPPVNPELTLTTTDVTPEENARKIIRY
LEEKGFLEG
>Mature_568_residues
PNDNLLISPYGGRLIDLCVSAEERDDVLAEASRLPSIQISMRSMCDLELLATGGFSPLTGFMGRADYERVLEEMRLADGT
LWPIPVTLPVEKSHFGSDRIVLRDVHNNPLAIMEISDIYRWDAEREALAVLGTTDPHHPLVAEMARWGKFYAAGRLRVIN
LPRYYDFTDLRRTPAEVRRLLQAMGRPNVVAFQTRNPMHRIHEELTKRAAAQVDGSLLIHPVVGMTKPGDIDHFTRVRSY
RLLVEKYYDPGRTLLSLLPLAMRMAGPREAVWHAIIRRNYGANHFIVGRDHAGPGNDSTGKPFYGPYAAQELLAHYAHEI
GVTMIPFTELVYLKREGRYVTIDEVPPGAEISSISGTQVRDEYLAKGRLLPEWFTRPETAEILRQMYPPRHRQGFCVWFT
GLSGAGKSTIAAILNVLLLERGRTPTVLDGDVVRTHLSKGLGFSREDRDTNILRIGFVASAVVKAGGAVICAAVSPYRAA
RNECRTMIGSDQFIEVFVDTPLEVCEQRDVKGLYAKARRGELRGFTGIDDPYEPPVNPELTLTTTDVTPEENARKIIRYL
EEKGFLEG

Specific function: Catalyzes The Synthesis Of Activated Sulfate. [C]

COG id: COG2046

COG function: function code P; ATP sulfurylase (sulfate adenylyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=173, Percent_Identity=48.5549132947977, Blast_Score=159, Evalue=9e-39,
Organism=Homo sapiens, GI62912492, Length=394, Percent_Identity=31.2182741116751, Blast_Score=149, Evalue=8e-36,
Organism=Homo sapiens, GI34447231, Length=389, Percent_Identity=31.3624678663239, Blast_Score=147, Evalue=2e-35,
Organism=Escherichia coli, GI1789107, Length=171, Percent_Identity=51.4619883040936, Blast_Score=162, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI17542422, Length=176, Percent_Identity=46.5909090909091, Blast_Score=150, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6322469, Length=399, Percent_Identity=48.8721804511278, Blast_Score=372, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6322852, Length=173, Percent_Identity=48.5549132947977, Blast_Score=154, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24667032, Length=177, Percent_Identity=48.5875706214689, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24667028, Length=177, Percent_Identity=48.5875706214689, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24667036, Length=177, Percent_Identity=48.5875706214689, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI116007838, Length=177, Percent_Identity=48.5875706214689, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24667044, Length=177, Percent_Identity=48.5875706214689, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24667040, Length=180, Percent_Identity=48.3333333333333, Blast_Score=159, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891
- InterPro:   IPR015947
- InterPro:   IPR014729
- InterPro:   IPR020792
- InterPro:   IPR002650 [H]

Pfam domain/function: PF01583 APS_kinase; PF01747 ATP-sulfurylase [H]

EC number: =2.7.7.4; =2.7.1.25 [H]

Molecular weight: Translated: 63820; Mature: 63689

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNDNLLISPYGGRLIDLCVSAEERDDVLAEASRLPSIQISMRSMCDLELLATGGFSPLT
CCCCCEEECCCCCCEEEEECCCCHHHHHHHHHHHCCEEEEEHHHHCCEEEEECCCCCHHH
GFMGRADYERVLEEMRLADGTLWPIPVTLPVEKSHFGSDRIVLRDVHNNPLAIMEISDIY
HHHCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCEEEEEEHHHH
RWDAEREALAVLGTTDPHHPLVAEMARWGKFYAAGRLRVINLPRYYDFTDLRRTPAEVRR
HCCCCCCEEEEEECCCCCCHHHHHHHHHHHHEECCEEEEEECCCCCCHHHHHCCHHHHHH
LLQAMGRPNVVAFQTRNPMHRIHEELTKRAAAQVDGSLLIHPVVGMTKPGDIDHFTRVRS
HHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHH
YRLLVEKYYDPGRTLLSLLPLAMRMAGPREAVWHAIIRRNYGANHFIVGRDHAGPGNDST
HHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
GKPFYGPYAAQELLAHYAHEIGVTMIPFTELVYLKREGRYVTIDEVPPGAEISSISGTQV
CCCCCCCHHHHHHHHHHHHHCCCEEECHHHEEEEEECCCEEEEECCCCCCCCCCCCCCHH
RDEYLAKGRLLPEWFTRPETAEILRQMYPPRHRQGFCVWFTGLSGAGKSTIAAILNVLLL
HHHHHHCCCCCHHHHCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
ERGRTPTVLDGDVVRTHLSKGLGFSREDRDTNILRIGFVASAVVKAGGAVICAAVSPYRA
HCCCCCCEECHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCEEEEECCHHHH
ARNECRTMIGSDQFIEVFVDTPLEVCEQRDVKGLYAKARRGELRGFTGIDDPYEPPVNPE
HHHHHHHHHCCCCEEEEEECCHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCE
LTLTTTDVTPEENARKIIRYLEEKGFLEG
EEEEEECCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PNDNLLISPYGGRLIDLCVSAEERDDVLAEASRLPSIQISMRSMCDLELLATGGFSPLT
CCCCEEECCCCCCEEEEECCCCHHHHHHHHHHHCCEEEEEHHHHCCEEEEECCCCCHHH
GFMGRADYERVLEEMRLADGTLWPIPVTLPVEKSHFGSDRIVLRDVHNNPLAIMEISDIY
HHHCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCEEEEEEHHHH
RWDAEREALAVLGTTDPHHPLVAEMARWGKFYAAGRLRVINLPRYYDFTDLRRTPAEVRR
HCCCCCCEEEEEECCCCCCHHHHHHHHHHHHEECCEEEEEECCCCCCHHHHHCCHHHHHH
LLQAMGRPNVVAFQTRNPMHRIHEELTKRAAAQVDGSLLIHPVVGMTKPGDIDHFTRVRS
HHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHH
YRLLVEKYYDPGRTLLSLLPLAMRMAGPREAVWHAIIRRNYGANHFIVGRDHAGPGNDST
HHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
GKPFYGPYAAQELLAHYAHEIGVTMIPFTELVYLKREGRYVTIDEVPPGAEISSISGTQV
CCCCCCCHHHHHHHHHHHHHCCCEEECHHHEEEEEECCCEEEEECCCCCCCCCCCCCCHH
RDEYLAKGRLLPEWFTRPETAEILRQMYPPRHRQGFCVWFTGLSGAGKSTIAAILNVLLL
HHHHHHCCCCCHHHHCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
ERGRTPTVLDGDVVRTHLSKGLGFSREDRDTNILRIGFVASAVVKAGGAVICAAVSPYRA
HCCCCCCEECHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCEEEEECCHHHH
ARNECRTMIGSDQFIEVFVDTPLEVCEQRDVKGLYAKARRGELRGFTGIDDPYEPPVNPE
HHHHHHHHHCCCCEEEEEECCHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCE
LTLTTTDVTPEENARKIIRYLEEKGFLEG
EEEEEECCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]