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The map label for this gene is ilvG [H]

Identifier: 222525500

GI number: 222525500

Start: 2845294

End: 2847828

Strand: Direct

Name: ilvG [H]

Synonym: Chy400_2248

Alternate gene names: 222525500

Gene position: 2845294-2847828 (Clockwise)

Preceding gene: 222525499

Following gene: 222525501

Centisome position: 54.0

GC content: 60.43

Gene sequence:

>2535_bases
ATGACGGCGACAATCTCTCGACGAGTCTGGTTGATCACCGGTGCCGGAGGTGGTTTTGGGCGCAGCCTCGTGCGACAGCT
TCTCGAACGTGGCGAGTATGTCGCTGCTGCCGACCGTAGCCTCGAACTGCTCGCCGCGCTACCTTCCTCAGAAGACGGAT
GTCTGTTTCCGGTTGCTATCGATCTTACCGATCCGATGACCATCCAGGCTGGTGTGGCAGCGGTGATCGACCGGTTTGGA
CGGATCGATGTGCTGGTGAATAACGCCGGTCTGGGTCACGGTGGCCCGCTCGAAGAGGTGTCATTGACCGACATCCGGCG
CCTGTTCGATGTCAATATCATCGGGATGATGCTGATCACGCAGGCTGTCTTGCCGGTGATGCGGGCGGCTGGGGGTGGGC
GGATTATCAATCTTTCATCGGATAGCGGGGTCATCGGCTTCCCGTTTCAAGGTCTCTACACTGCAACCAAGCATGCAGTG
GAAGGTTTTTCCGACAGTCTGTATCAAGAGGTGGCTCCGTTCGGCATCCACGTCTCGGTCGTTCAACCCTGTGGGATGTT
CAAGACGGCGATGCCGGCGAATGCGATTGCCCAGGCCCGTTCAGCGCTGAAACCTGATAGTCCCTACGCTGATCGTGTCT
TACGAATGGCGTCTGCCCTATCCGCTGCCTGGGAGACAGCGCGTGATCCCGCTGAAGTTGCCCAGGCCATTCTCGACGTT
GCCGATGCCGATCCGCCACCGATTCGTCGGCGAGTTGGCGCTCCTGAGCGTACCGGCTTGCTGGGTCTGCGTCAGCAGAT
GAGTCACGATGATCTGGTACGGTTTATCTACCGGCTGACAGCCGAACCAACGCCACCACCGTTGCCGAAAGTGCGCGGTG
ATGGTGGCTGGCTGGTGGTACGCACATTGCGGGAAGCGGGTATCACCCATGCCTTCACCATTGTTGGTGGTCACAACTAT
CAGATCGTCAATGCCTGTCGTGAAGAGGGCTTGTGTGTCATCGATGCCCGCAACGAAATGCATGCCGCCCATATGGCCGA
TGCGTTTGCCCGACTGGCGCGTCGTCCTGCCTTGCTCACCGTTGATGCTGCGCCGGGGTTGGTGAATGCGGTGGCCGGGA
TCGAGGTAGCTTATGAAGCGCAGGTGCCGATGATTGTCGTTTCGGCGCAGGGTTCACTGGCCGGACGGGATATTGGAGTC
ATGCAGGCGATTGACCAGCTCCGGCTCGTGCGCCCGATCACAAAATGGCAACGCACCTGCTTCGAGACCAGGCGCCTACC
CGAATACACGGCTGCTGCCATCAGACATGCAACTACCGGTCGGCCTGGGCCGACCTTTCTGGACTTTCCACTTGAGGTGA
TGCAGGCGACCATTGATGTTGAGACCGTCCCTCAACCGCGTCACTATCGGGTGACGAGCGGCCCGCTGGCCGATCCCGAC
TTGCTCCGGCAGGTGATCGAGATGCTACGCAAGGCACGTCGGCCCCTGATTATTGCCGGCAGCGGGGTCTGGTGGGCGCA
CGGCGAAGCCGAACTCGTTCGCTTTGTCCAGACAACCGGCATTCCGGTGTTGACGCGCAACCTGGCACGCGGCATCATCC
CTGACGATCATCCGCTGGCAGCCGGCTTTTACCCGTCTCCCGCCGCCCTGGCCGACGCCTTTCTGGTTATCGGCACCCGG
CTCGATTGGACAATCGGTTATGGACGACCGCCGCTCTTCTCGCCTGATGCACCGGTAGCCCAGATTGATCTCCATCCCGA
AAGTATCGGCAAGACACGACCGATTGAGATCGGAATTGTCGCCGATGCGGCGCAGGCACTGCGGCAATTGAACGCAATGG
TGTCGGCAACCGGGCCGTGGACAATGGATGCAGAATGGCCGGCGCTGGCGCACGGTAGTATCGCTGCAATGCGCCAGCAA
ACGGCTGCTGCGGCCCAATTATCAACCCGCGATCAACGACCAATCCATTCGATTGAACTGATGCAGGCGCTGGCCGAATG
CCTTCCCCGCGAAGCGATCAAGGTTGTCGATGGCGGTTACAGTGCAGCCTTCGCCATCCAATACCTCGACGCTTACGTCC
CCAGCGGCGTGCTGTGGGTTGGCAGTACCGGACATCTCGGCGTCGGCTTAGGCTTTGCTATCGGGGCCAAACGGGCCAGA
CCCGATGCACCGGTGGTGGCAATTATGGGTGATGGTGCCTTTGGTCTCTGTGGGATGGAGTTTGATACCGCGGTACGCCA
CCAGTTGCCGATTGTGGTAGTCGTCGCCAACGATGCCGGTTGGGGTGAAACGCGCGACGGTCAGCGACGACGGTGGGGAG
ACGCAGCCATCGTCGGCACAGCGCTCAATCCAACCCGCTACGATGAACTGGCCCGTGCTCTCGGCGGGCACGGCGAATAT
GTCACGCGCCTCGACGAACTGGCGCCGGCTATACGGCGCGCTTTTGCAGCGGGAAAACCGGCATTGATCAACGTCATCAC
CGATCCCGAACAACGCAGCAGTGCCGTCAGCGGTCTGCCGTGGATTGTAGAGTAG

Upstream 100 bases:

>100_bases
TTTTAGCGGTAGTTCCTGTCACCCGCTGCCTGGATGTTGGTTGCCACTGATGGTTTGCTGGCCTTGCTTGTGATGCGGCA
TAGCTGCAGGAAGGGGTAGT

Downstream 100 bases:

>100_bases
AATAACCGGTAAGCGATTCTGCTTTCAAGCCAGGTATTCATCAAGGAGGATGCGATGACCCCGGTGGCCGCTGCATTAAG
TTATCTTACGGAACATCGTG

Product: thiamine pyrophosphate protein

Products: NA

Alternate protein names: ALS; Acetohydroxy-acid synthase [H]

Number of amino acids: Translated: 844; Mature: 843

Protein sequence:

>844_residues
MTATISRRVWLITGAGGGFGRSLVRQLLERGEYVAAADRSLELLAALPSSEDGCLFPVAIDLTDPMTIQAGVAAVIDRFG
RIDVLVNNAGLGHGGPLEEVSLTDIRRLFDVNIIGMMLITQAVLPVMRAAGGGRIINLSSDSGVIGFPFQGLYTATKHAV
EGFSDSLYQEVAPFGIHVSVVQPCGMFKTAMPANAIAQARSALKPDSPYADRVLRMASALSAAWETARDPAEVAQAILDV
ADADPPPIRRRVGAPERTGLLGLRQQMSHDDLVRFIYRLTAEPTPPPLPKVRGDGGWLVVRTLREAGITHAFTIVGGHNY
QIVNACREEGLCVIDARNEMHAAHMADAFARLARRPALLTVDAAPGLVNAVAGIEVAYEAQVPMIVVSAQGSLAGRDIGV
MQAIDQLRLVRPITKWQRTCFETRRLPEYTAAAIRHATTGRPGPTFLDFPLEVMQATIDVETVPQPRHYRVTSGPLADPD
LLRQVIEMLRKARRPLIIAGSGVWWAHGEAELVRFVQTTGIPVLTRNLARGIIPDDHPLAAGFYPSPAALADAFLVIGTR
LDWTIGYGRPPLFSPDAPVAQIDLHPESIGKTRPIEIGIVADAAQALRQLNAMVSATGPWTMDAEWPALAHGSIAAMRQQ
TAAAAQLSTRDQRPIHSIELMQALAECLPREAIKVVDGGYSAAFAIQYLDAYVPSGVLWVGSTGHLGVGLGFAIGAKRAR
PDAPVVAIMGDGAFGLCGMEFDTAVRHQLPIVVVVANDAGWGETRDGQRRRWGDAAIVGTALNPTRYDELARALGGHGEY
VTRLDELAPAIRRAFAAGKPALINVITDPEQRSSAVSGLPWIVE

Sequences:

>Translated_844_residues
MTATISRRVWLITGAGGGFGRSLVRQLLERGEYVAAADRSLELLAALPSSEDGCLFPVAIDLTDPMTIQAGVAAVIDRFG
RIDVLVNNAGLGHGGPLEEVSLTDIRRLFDVNIIGMMLITQAVLPVMRAAGGGRIINLSSDSGVIGFPFQGLYTATKHAV
EGFSDSLYQEVAPFGIHVSVVQPCGMFKTAMPANAIAQARSALKPDSPYADRVLRMASALSAAWETARDPAEVAQAILDV
ADADPPPIRRRVGAPERTGLLGLRQQMSHDDLVRFIYRLTAEPTPPPLPKVRGDGGWLVVRTLREAGITHAFTIVGGHNY
QIVNACREEGLCVIDARNEMHAAHMADAFARLARRPALLTVDAAPGLVNAVAGIEVAYEAQVPMIVVSAQGSLAGRDIGV
MQAIDQLRLVRPITKWQRTCFETRRLPEYTAAAIRHATTGRPGPTFLDFPLEVMQATIDVETVPQPRHYRVTSGPLADPD
LLRQVIEMLRKARRPLIIAGSGVWWAHGEAELVRFVQTTGIPVLTRNLARGIIPDDHPLAAGFYPSPAALADAFLVIGTR
LDWTIGYGRPPLFSPDAPVAQIDLHPESIGKTRPIEIGIVADAAQALRQLNAMVSATGPWTMDAEWPALAHGSIAAMRQQ
TAAAAQLSTRDQRPIHSIELMQALAECLPREAIKVVDGGYSAAFAIQYLDAYVPSGVLWVGSTGHLGVGLGFAIGAKRAR
PDAPVVAIMGDGAFGLCGMEFDTAVRHQLPIVVVVANDAGWGETRDGQRRRWGDAAIVGTALNPTRYDELARALGGHGEY
VTRLDELAPAIRRAFAAGKPALINVITDPEQRSSAVSGLPWIVE
>Mature_843_residues
TATISRRVWLITGAGGGFGRSLVRQLLERGEYVAAADRSLELLAALPSSEDGCLFPVAIDLTDPMTIQAGVAAVIDRFGR
IDVLVNNAGLGHGGPLEEVSLTDIRRLFDVNIIGMMLITQAVLPVMRAAGGGRIINLSSDSGVIGFPFQGLYTATKHAVE
GFSDSLYQEVAPFGIHVSVVQPCGMFKTAMPANAIAQARSALKPDSPYADRVLRMASALSAAWETARDPAEVAQAILDVA
DADPPPIRRRVGAPERTGLLGLRQQMSHDDLVRFIYRLTAEPTPPPLPKVRGDGGWLVVRTLREAGITHAFTIVGGHNYQ
IVNACREEGLCVIDARNEMHAAHMADAFARLARRPALLTVDAAPGLVNAVAGIEVAYEAQVPMIVVSAQGSLAGRDIGVM
QAIDQLRLVRPITKWQRTCFETRRLPEYTAAAIRHATTGRPGPTFLDFPLEVMQATIDVETVPQPRHYRVTSGPLADPDL
LRQVIEMLRKARRPLIIAGSGVWWAHGEAELVRFVQTTGIPVLTRNLARGIIPDDHPLAAGFYPSPAALADAFLVIGTRL
DWTIGYGRPPLFSPDAPVAQIDLHPESIGKTRPIEIGIVADAAQALRQLNAMVSATGPWTMDAEWPALAHGSIAAMRQQT
AAAAQLSTRDQRPIHSIELMQALAECLPREAIKVVDGGYSAAFAIQYLDAYVPSGVLWVGSTGHLGVGLGFAIGAKRARP
DAPVVAIMGDGAFGLCGMEFDTAVRHQLPIVVVVANDAGWGETRDGQRRRWGDAAIVGTALNPTRYDELARALGGHGEYV
TRLDELAPAIRRAFAAGKPALINVITDPEQRSSAVSGLPWIVE

Specific function: Oxalic acid catabolism; second step. [C]

COG id: COG0028

COG function: function code EH; Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TPP enzyme family [H]

Homologues:

Organism=Homo sapiens, GI93004078, Length=555, Percent_Identity=28.2882882882883, Blast_Score=250, Evalue=4e-66,
Organism=Homo sapiens, GI21361361, Length=550, Percent_Identity=31.6363636363636, Blast_Score=223, Evalue=5e-58,
Organism=Homo sapiens, GI223718074, Length=256, Percent_Identity=32.8125, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI7657478, Length=255, Percent_Identity=32.9411764705882, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI40548397, Length=209, Percent_Identity=34.4497607655502, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI214010158, Length=209, Percent_Identity=34.4497607655502, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI214010156, Length=209, Percent_Identity=34.4497607655502, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI22758144, Length=209, Percent_Identity=34.4497607655502, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI20149619, Length=245, Percent_Identity=30.2040816326531, Blast_Score=104, Evalue=4e-22,
Organism=Homo sapiens, GI22507405, Length=206, Percent_Identity=33.9805825242718, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI7706318, Length=197, Percent_Identity=34.5177664974619, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI150247226, Length=187, Percent_Identity=36.3636363636364, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI19743808, Length=184, Percent_Identity=38.0434782608696, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI157739938, Length=189, Percent_Identity=31.2169312169312, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI44680136, Length=181, Percent_Identity=33.7016574585635, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI44680133, Length=181, Percent_Identity=33.7016574585635, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI17738292, Length=181, Percent_Identity=33.7016574585635, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI109715829, Length=180, Percent_Identity=31.6666666666667, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI19923817, Length=184, Percent_Identity=29.3478260869565, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI4503817, Length=182, Percent_Identity=26.3736263736264, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI59889578, Length=162, Percent_Identity=33.9506172839506, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI50726952, Length=182, Percent_Identity=36.2637362637363, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI40254992, Length=184, Percent_Identity=30.4347826086957, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI31542939, Length=197, Percent_Identity=29.9492385786802, Blast_Score=81, Evalue=5e-15,
Organism=Homo sapiens, GI7705855, Length=185, Percent_Identity=31.8918918918919, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=31.1764705882353, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI4504505, Length=211, Percent_Identity=31.2796208530806, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI119392083, Length=194, Percent_Identity=31.4432989690722, Blast_Score=77, Evalue=9e-14,
Organism=Homo sapiens, GI210032110, Length=175, Percent_Identity=29.1428571428571, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI142976729, Length=176, Percent_Identity=27.8409090909091, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI7705925, Length=178, Percent_Identity=33.1460674157303, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI4758504, Length=260, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=9e-11,
Organism=Escherichia coli, GI1788716, Length=545, Percent_Identity=30.8256880733945, Blast_Score=222, Evalue=8e-59,
Organism=Escherichia coli, GI87081685, Length=544, Percent_Identity=27.5735294117647, Blast_Score=169, Evalue=9e-43,
Organism=Escherichia coli, GI1790104, Length=554, Percent_Identity=26.5342960288809, Blast_Score=165, Evalue=9e-42,
Organism=Escherichia coli, GI1786717, Length=570, Percent_Identity=26.6666666666667, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1787096, Length=550, Percent_Identity=23.6363636363636, Blast_Score=125, Evalue=9e-30,
Organism=Escherichia coli, GI1787820, Length=239, Percent_Identity=30.1255230125523, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082100, Length=206, Percent_Identity=34.4660194174757, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1786701, Length=209, Percent_Identity=31.5789473684211, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1787335, Length=185, Percent_Identity=31.8918918918919, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1788459, Length=210, Percent_Identity=29.5238095238095, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788891, Length=187, Percent_Identity=30.4812834224599, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789057, Length=217, Percent_Identity=28.110599078341, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI87082160, Length=185, Percent_Identity=25.9459459459459, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1790717, Length=184, Percent_Identity=31.5217391304348, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI2367365, Length=189, Percent_Identity=31.7460317460317, Blast_Score=63, Evalue=7e-11,
Organism=Escherichia coli, GI2367175, Length=196, Percent_Identity=30.1020408163265, Blast_Score=63, Evalue=8e-11,
Organism=Escherichia coli, GI1787905, Length=136, Percent_Identity=28.6764705882353, Blast_Score=63, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17542570, Length=599, Percent_Identity=29.3823038397329, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17531301, Length=562, Percent_Identity=28.1138790035587, Blast_Score=200, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17531299, Length=562, Percent_Identity=28.1138790035587, Blast_Score=200, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=31.4720812182741, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17568967, Length=223, Percent_Identity=31.390134529148, Blast_Score=93, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI115534660, Length=192, Percent_Identity=31.25, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71997402, Length=200, Percent_Identity=31.5, Blast_Score=86, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17570069, Length=201, Percent_Identity=29.8507462686567, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=240, Percent_Identity=29.5833333333333, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17557780, Length=201, Percent_Identity=29.3532338308458, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=182, Percent_Identity=31.3186813186813, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32563809, Length=198, Percent_Identity=28.7878787878788, Blast_Score=77, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17507613, Length=198, Percent_Identity=28.7878787878788, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=203, Percent_Identity=28.0788177339901, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193210355, Length=190, Percent_Identity=29.4736842105263, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320816, Length=566, Percent_Identity=27.208480565371, Blast_Score=180, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6323755, Length=566, Percent_Identity=24.3816254416961, Blast_Score=134, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6323882, Length=195, Percent_Identity=34.3589743589744, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322861, Length=215, Percent_Identity=29.3023255813954, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322067, Length=176, Percent_Identity=28.4090909090909, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322226, Length=218, Percent_Identity=28.4403669724771, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI19922626, Length=567, Percent_Identity=29.2768959435626, Blast_Score=235, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24643142, Length=184, Percent_Identity=35.8695652173913, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=33.1632653061224, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571526, Length=185, Percent_Identity=31.8918918918919, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI23397609, Length=183, Percent_Identity=32.7868852459016, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357041, Length=180, Percent_Identity=31.6666666666667, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21355631, Length=175, Percent_Identity=30.2857142857143, Blast_Score=84, Evalue=6e-16,
Organism=Drosophila melanogaster, GI116007238, Length=206, Percent_Identity=30.0970873786408, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281364892, Length=176, Percent_Identity=31.8181818181818, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI116007236, Length=184, Percent_Identity=30.4347826086957, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21356301, Length=189, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24639444, Length=198, Percent_Identity=32.3232323232323, Blast_Score=80, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24651139, Length=260, Percent_Identity=28.4615384615385, Blast_Score=78, Evalue=3e-14,
Organism=Drosophila melanogaster, GI18859837, Length=191, Percent_Identity=33.5078534031414, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641232, Length=210, Percent_Identity=29.5238095238095, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17737361, Length=230, Percent_Identity=27.3913043478261, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24580925, Length=190, Percent_Identity=29.4736842105263, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584748, Length=180, Percent_Identity=31.1111111111111, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640442, Length=192, Percent_Identity=31.25, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161076933, Length=180, Percent_Identity=31.1111111111111, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24644339, Length=180, Percent_Identity=29.4444444444444, Blast_Score=71, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640492, Length=170, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24648944, Length=190, Percent_Identity=28.4210526315789, Blast_Score=70, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24581726, Length=164, Percent_Identity=30.4878048780488, Blast_Score=69, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28574402, Length=230, Percent_Identity=30, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24584744, Length=230, Percent_Identity=30, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012000
- InterPro:   IPR012001
- InterPro:   IPR000399
- InterPro:   IPR011766 [H]

Pfam domain/function: PF02775 TPP_enzyme_C; PF00205 TPP_enzyme_M; PF02776 TPP_enzyme_N [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 90487; Mature: 90356

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00187 TPP_ENZYMES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATISRRVWLITGAGGGFGRSLVRQLLERGEYVAAADRSLELLAALPSSEDGCLFPVAI
CCCEECCEEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCEEEEEECCCCCCCEEEEEEE
DLTDPMTIQAGVAAVIDRFGRIDVLVNNAGLGHGGPLEEVSLTDIRRLFDVNIIGMMLIT
ECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QAVLPVMRAAGGGRIINLSSDSGVIGFPFQGLYTATKHAVEGFSDSLYQEVAPFGIHVSV
HHHHHHHHCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
VQPCGMFKTAMPANAIAQARSALKPDSPYADRVLRMASALSAAWETARDPAEVAQAILDV
ECCCCCHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ADADPPPIRRRVGAPERTGLLGLRQQMSHDDLVRFIYRLTAEPTPPPLPKVRGDGGWLVV
HCCCCCHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
RTLREAGITHAFTIVGGHNYQIVNACREEGLCVIDARNEMHAAHMADAFARLARRPALLT
EEHHHCCCEEEEEEEECCCCHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEE
VDAAPGLVNAVAGIEVAYEAQVPMIVVSAQGSLAGRDIGVMQAIDQLRLVRPITKWQRTC
EECCCCHHHHHHCCEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FETRRLPEYTAAAIRHATTGRPGPTFLDFPLEVMQATIDVETVPQPRHYRVTSGPLADPD
HHHHCCCHHHHHHHHHHCCCCCCCCEECCCHHHHHHHCCCCCCCCCCCEEECCCCCCCHH
LLRQVIEMLRKARRPLIIAGSGVWWAHGEAELVRFVQTTGIPVLTRNLARGIIPDDHPLA
HHHHHHHHHHHCCCCEEEECCCEEEECCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCC
AGFYPSPAALADAFLVIGTRLDWTIGYGRPPLFSPDAPVAQIDLHPESIGKTRPIEIGIV
CCCCCCHHHHHHHHHHEECEEEEEECCCCCCCCCCCCCEEEEECCHHHCCCCCCEEEEEE
ADAAQALRQLNAMVSATGPWTMDAEWPALAHGSIAAMRQQTAAAAQLSTRDQRPIHSIEL
HHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
MQALAECLPREAIKVVDGGYSAAFAIQYLDAYVPSGVLWVGSTGHLGVGLGFAIGAKRAR
HHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHCCCCCC
PDAPVVAIMGDGAFGLCGMEFDTAVRHQLPIVVVVANDAGWGETRDGQRRRWGDAAIVGT
CCCCEEEEECCCCEEEECCCHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHCCCEEEEEE
ALNPTRYDELARALGGHGEYVTRLDELAPAIRRAFAAGKPALINVITDPEQRSSAVSGLP
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCC
WIVE
CCCC
>Mature Secondary Structure 
TATISRRVWLITGAGGGFGRSLVRQLLERGEYVAAADRSLELLAALPSSEDGCLFPVAI
CCEECCEEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCEEEEEECCCCCCCEEEEEEE
DLTDPMTIQAGVAAVIDRFGRIDVLVNNAGLGHGGPLEEVSLTDIRRLFDVNIIGMMLIT
ECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QAVLPVMRAAGGGRIINLSSDSGVIGFPFQGLYTATKHAVEGFSDSLYQEVAPFGIHVSV
HHHHHHHHCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
VQPCGMFKTAMPANAIAQARSALKPDSPYADRVLRMASALSAAWETARDPAEVAQAILDV
ECCCCCHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ADADPPPIRRRVGAPERTGLLGLRQQMSHDDLVRFIYRLTAEPTPPPLPKVRGDGGWLVV
HCCCCCHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
RTLREAGITHAFTIVGGHNYQIVNACREEGLCVIDARNEMHAAHMADAFARLARRPALLT
EEHHHCCCEEEEEEEECCCCHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEE
VDAAPGLVNAVAGIEVAYEAQVPMIVVSAQGSLAGRDIGVMQAIDQLRLVRPITKWQRTC
EECCCCHHHHHHCCEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FETRRLPEYTAAAIRHATTGRPGPTFLDFPLEVMQATIDVETVPQPRHYRVTSGPLADPD
HHHHCCCHHHHHHHHHHCCCCCCCCEECCCHHHHHHHCCCCCCCCCCCEEECCCCCCCHH
LLRQVIEMLRKARRPLIIAGSGVWWAHGEAELVRFVQTTGIPVLTRNLARGIIPDDHPLA
HHHHHHHHHHHCCCCEEEECCCEEEECCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCC
AGFYPSPAALADAFLVIGTRLDWTIGYGRPPLFSPDAPVAQIDLHPESIGKTRPIEIGIV
CCCCCCHHHHHHHHHHEECEEEEEECCCCCCCCCCCCCEEEEECCHHHCCCCCCEEEEEE
ADAAQALRQLNAMVSATGPWTMDAEWPALAHGSIAAMRQQTAAAAQLSTRDQRPIHSIEL
HHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
MQALAECLPREAIKVVDGGYSAAFAIQYLDAYVPSGVLWVGSTGHLGVGLGFAIGAKRAR
HHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHCCCCCC
PDAPVVAIMGDGAFGLCGMEFDTAVRHQLPIVVVVANDAGWGETRDGQRRRWGDAAIVGT
CCCCEEEEECCCCEEEECCCHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHCCCEEEEEE
ALNPTRYDELARALGGHGEYVTRLDELAPAIRRAFAAGKPALINVITDPEQRSSAVSGLP
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCC
WIVE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]