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The map label for this gene is pyrD [H]

Identifier: 222525496

GI number: 222525496

Start: 2840364

End: 2841428

Strand: Direct

Name: pyrD [H]

Synonym: Chy400_2244

Alternate gene names: 222525496

Gene position: 2840364-2841428 (Clockwise)

Preceding gene: 222525495

Following gene: 222525497

Centisome position: 53.91

GC content: 56.71

Gene sequence:

>1065_bases
ATGATTGATCTGAGTACGACCTATCTGGGGATGCCACTGCGCACACCGCTGGTCGCTGCGGCATCTCCGATTAGCCGGAA
CGTTGAGCTGGCCCGCCAGCTTGAAGAGGCCGGCCTGGGCGCAATCGTGATGTATTCGCTCTTCGAGGAACAGATCATTC
AAAACAGCCTCGAACTTGATCGGATGCTCAGCTACGGCGCCGAGAGTTTCGCCGAAGCGCTCAGCTATCTGCCCGAACAC
GGTGTGTACAGCGTTGGCCCGGAACGCTATCTCGAACAGGTGGCGGCATTGAAACGCGCATTGAGTATTCCGGTGATCGG
CAGCCTCAACGGCGTGTCGGCAGGTGGCTGGGTGCGTTATGCCCGTCTGATCCAGGAAGCGGGAGCAGATGCACTCGAAT
TAAATATCTATTTCATACCGGTGGATACCAACATCACCAGCAGTGAACTCGAAGATACGTATGTGGAACTGGTGCGTGCC
GTGCGGGCCGAGATCACCATTCCCCTGGCGGTCAAGATTGGCCCCTATTTCACCGCCTTGCCCAATTTCGCCTGGCGATT
GATGGAAGCCGGTGCGAATGCACTGGTGCTGTTTAACCGCTTTTACCAGCCCGATTTCGACCTCGAACAACTGACAGTGC
GCCCGAACCTGCAACTGAGCACATCAGCCGAATTACGTCTGCCACTACGCTGGATTGCCCTGCTCTACGGGCGGATTCCA
GTGGAGTTCGCGATTAGCAGTGGTGTGCATAGCGCCATTGATGCTCTGAAGGGCTTGATGGCAGGTGCCAGCGTAGCCAT
GATGGCTTCAGCCCTACTGCGTGGGCGGGCACCCGATGTCTTGCGCAGTGTTCTGCACGATATGGAATTATGGCTCACCG
AACACGAGTATGAGTCGATTTCACAACTCCGTGGGAGTATGAGCCAGCGGGCAGTGGCCGAGCCGGCAGCGTTTGAGCGG
GCAAACTACATTCGGGTACTGGAAGATTACCGGCCACCGTATGCGTTGGGGAGCCATACCGATCTGACCGGTCGGATGCT
CTATCCATTTATCGACGAGACATAG

Upstream 100 bases:

>100_bases
AACAGTTGCTCGCCAGTTTGCGGCGGCAGGTAGCGCTGAAATGGGCCCATTTACAGTGGATGGCAAATGAGCTGCTGGCT
GAAACCAAGGAGGGGCTGCG

Downstream 100 bases:

>100_bases
TCTTTAACGCGCGCATTGCTGTCTTCCTTGCCACCGACGGTCTGGACACCCAGACCGTCGGTGTGTTGATGAGCAATGAT
CTTGAACGGATAAGATACTC

Product: dihydroorotate dehydrogenase

Products: NA

Alternate protein names: DHOdehase; DHOD; DHODase; Dihydroorotate oxidase [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MIDLSTTYLGMPLRTPLVAAASPISRNVELARQLEEAGLGAIVMYSLFEEQIIQNSLELDRMLSYGAESFAEALSYLPEH
GVYSVGPERYLEQVAALKRALSIPVIGSLNGVSAGGWVRYARLIQEAGADALELNIYFIPVDTNITSSELEDTYVELVRA
VRAEITIPLAVKIGPYFTALPNFAWRLMEAGANALVLFNRFYQPDFDLEQLTVRPNLQLSTSAELRLPLRWIALLYGRIP
VEFAISSGVHSAIDALKGLMAGASVAMMASALLRGRAPDVLRSVLHDMELWLTEHEYESISQLRGSMSQRAVAEPAAFER
ANYIRVLEDYRPPYALGSHTDLTGRMLYPFIDET

Sequences:

>Translated_354_residues
MIDLSTTYLGMPLRTPLVAAASPISRNVELARQLEEAGLGAIVMYSLFEEQIIQNSLELDRMLSYGAESFAEALSYLPEH
GVYSVGPERYLEQVAALKRALSIPVIGSLNGVSAGGWVRYARLIQEAGADALELNIYFIPVDTNITSSELEDTYVELVRA
VRAEITIPLAVKIGPYFTALPNFAWRLMEAGANALVLFNRFYQPDFDLEQLTVRPNLQLSTSAELRLPLRWIALLYGRIP
VEFAISSGVHSAIDALKGLMAGASVAMMASALLRGRAPDVLRSVLHDMELWLTEHEYESISQLRGSMSQRAVAEPAAFER
ANYIRVLEDYRPPYALGSHTDLTGRMLYPFIDET
>Mature_354_residues
MIDLSTTYLGMPLRTPLVAAASPISRNVELARQLEEAGLGAIVMYSLFEEQIIQNSLELDRMLSYGAESFAEALSYLPEH
GVYSVGPERYLEQVAALKRALSIPVIGSLNGVSAGGWVRYARLIQEAGADALELNIYFIPVDTNITSSELEDTYVELVRA
VRAEITIPLAVKIGPYFTALPNFAWRLMEAGANALVLFNRFYQPDFDLEQLTVRPNLQLSTSAELRLPLRWIALLYGRIP
VEFAISSGVHSAIDALKGLMAGASVAMMASALLRGRAPDVLRSVLHDMELWLTEHEYESISQLRGSMSQRAVAEPAAFER
ANYIRVLEDYRPPYALGSHTDLTGRMLYPFIDET

Specific function: Unknown

COG id: COG0167

COG function: function code F; Dihydroorotate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082059, Length=322, Percent_Identity=22.360248447205, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005720
- InterPro:   IPR012135
- InterPro:   IPR001295 [H]

Pfam domain/function: PF01180 DHO_dh [H]

EC number: =1.3.3.1 [H]

Molecular weight: Translated: 39234; Mature: 39234

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLSTTYLGMPLRTPLVAAASPISRNVELARQLEEAGLGAIVMYSLFEEQIIQNSLELD
CCCCCCCEECCCCCCCHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RMLSYGAESFAEALSYLPEHGVYSVGPERYLEQVAALKRALSIPVIGSLNGVSAGGWVRY
HHHHHCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHH
ARLIQEAGADALELNIYFIPVDTNITSSELEDTYVELVRAVRAEITIPLAVKIGPYFTAL
HHHHHHCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHEEEEEEEEECCHHHHH
PNFAWRLMEAGANALVLFNRFYQPDFDLEQLTVRPNLQLSTSAELRLPLRWIALLYGRIP
HHHHHHHHHCCCCEEEEEHHHCCCCCCHHHEEECCCCEECCCCCCCHHHHHHHHHHCCCC
VEFAISSGVHSAIDALKGLMAGASVAMMASALLRGRAPDVLRSVLHDMELWLTEHEYESI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
SQLRGSMSQRAVAEPAAFERANYIRVLEDYRPPYALGSHTDLTGRMLYPFIDET
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCC
>Mature Secondary Structure
MIDLSTTYLGMPLRTPLVAAASPISRNVELARQLEEAGLGAIVMYSLFEEQIIQNSLELD
CCCCCCCEECCCCCCCHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RMLSYGAESFAEALSYLPEHGVYSVGPERYLEQVAALKRALSIPVIGSLNGVSAGGWVRY
HHHHHCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHH
ARLIQEAGADALELNIYFIPVDTNITSSELEDTYVELVRAVRAEITIPLAVKIGPYFTAL
HHHHHHCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHEEEEEEEEECCHHHHH
PNFAWRLMEAGANALVLFNRFYQPDFDLEQLTVRPNLQLSTSAELRLPLRWIALLYGRIP
HHHHHHHHHCCCCEEEEEHHHCCCCCCHHHEEECCCCEECCCCCCCHHHHHHHHHHCCCC
VEFAISSGVHSAIDALKGLMAGASVAMMASALLRGRAPDVLRSVLHDMELWLTEHEYESI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
SQLRGSMSQRAVAEPAAFERANYIRVLEDYRPPYALGSHTDLTGRMLYPFIDET
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11029001 [H]