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The map label for this gene is qor [H]

Identifier: 222525372

GI number: 222525372

Start: 2690202

End: 2691170

Strand: Direct

Name: qor [H]

Synonym: Chy400_2117

Alternate gene names: 222525372

Gene position: 2690202-2691170 (Clockwise)

Preceding gene: 222525365

Following gene: 222525373

Centisome position: 51.06

GC content: 59.34

Gene sequence:

>969_bases
ATGCGGGCGATCCAGATTCATCAGACCGGTGGGCCAGAGCAGTTGCAGATGGTTGATATTCCCCTTCCCGAACCTGCACC
AGGACAGGTGCGGATTAAGGTGGCCGCGGCGGGGGTTAATTTTATCGATATCTACCATCGTACCGGTCTCTATCCACAAC
CGTTGCCGTTTACTCTGGGGTTAGAAGTGGCCGGTACGATTGATGCCGTTGGCGAAGGGGTGAGTGAATGGGCAGTCGGT
GACCGGGTTGGGTGTACGACCGCCAGCGGCGGCTACGCCGAATATGCCCTGGCCGCAGCCGATAAGCTGGTACGGGTGCC
CGATAATGTCGATTTGGAGACAGCAGCGGCAGTGCTCCTGCAGGGCATGACAGCCCACTATCTGACGTTCAGCACCTTTC
CGCTGAAAGCAGGGGATACCTGTCTGGTGCATGCTGCGGCGGGTGGCGTAGGTCTGTTGTTGATCCAGATTGCCCGGCGT
TTGGGAGCACGGGTGATTGGCACCGTTTCGACTGATGAAAAAGCCGAACTGGCCCGCGCAGCCGGTGCCGATGAAGTGGT
GATCTATACCCGCGAGTCGTTTGTCGAGCGGGTGCGGGCGTTTACCAACGGTCGTGGGGTCGATGTGGTCTACGACTCGG
TCGGTGCCAGTACGCTGGAAGGCAGTCTCGATAGCCTGCGTCCACGGGGGATGTTCGTTACCTTTGGCAATGCCAGTGGC
CCCTTGCCGCCGATCTCACCATTGTTGCTGAGTAGCAAGGGTTCGCTGTTTATGACGCGGCCCACCCTCTTCCACTACAT
TGCCACGCCTGAAGAGTTGCGCTGGCGCGCCAGTGATCTGTTTACCTGGATCGGTGCCGGCGAGTTGCAGGTTCGCATTC
ACCGGCGGTATCCGCTGAGTGAAGCGGCTGAGGCGCAGATTGCCCTGGCCAGTCGGGCCACTACTGGCAAGTTGTTACTG
ATCCCGTAA

Upstream 100 bases:

>100_bases
ATTTGACGTAAACGCTATAACATCAAAGTGATCGCACTATGTTATAGTATAGGTCGGTTTTCGATCCGAGCGCAAGGGTG
AGCTTTCAGCGAGGTGCGTC

Downstream 100 bases:

>100_bases
TTGGCCTGTTGCCATACAGTCGGGATTTCTTCCTGGTATCTACGTCGCGGAGATGCGCAGCACAGCGCTCCGCGACGTTT
TTTCATAAGTAGAGAGGAGA

Product: alcohol dehydrogenase zinc-binding domain-containing protein

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MRAIQIHQTGGPEQLQMVDIPLPEPAPGQVRIKVAAAGVNFIDIYHRTGLYPQPLPFTLGLEVAGTIDAVGEGVSEWAVG
DRVGCTTASGGYAEYALAAADKLVRVPDNVDLETAAAVLLQGMTAHYLTFSTFPLKAGDTCLVHAAAGGVGLLLIQIARR
LGARVIGTVSTDEKAELARAAGADEVVIYTRESFVERVRAFTNGRGVDVVYDSVGASTLEGSLDSLRPRGMFVTFGNASG
PLPPISPLLLSSKGSLFMTRPTLFHYIATPEELRWRASDLFTWIGAGELQVRIHRRYPLSEAAEAQIALASRATTGKLLL
IP

Sequences:

>Translated_322_residues
MRAIQIHQTGGPEQLQMVDIPLPEPAPGQVRIKVAAAGVNFIDIYHRTGLYPQPLPFTLGLEVAGTIDAVGEGVSEWAVG
DRVGCTTASGGYAEYALAAADKLVRVPDNVDLETAAAVLLQGMTAHYLTFSTFPLKAGDTCLVHAAAGGVGLLLIQIARR
LGARVIGTVSTDEKAELARAAGADEVVIYTRESFVERVRAFTNGRGVDVVYDSVGASTLEGSLDSLRPRGMFVTFGNASG
PLPPISPLLLSSKGSLFMTRPTLFHYIATPEELRWRASDLFTWIGAGELQVRIHRRYPLSEAAEAQIALASRATTGKLLL
IP
>Mature_322_residues
MRAIQIHQTGGPEQLQMVDIPLPEPAPGQVRIKVAAAGVNFIDIYHRTGLYPQPLPFTLGLEVAGTIDAVGEGVSEWAVG
DRVGCTTASGGYAEYALAAADKLVRVPDNVDLETAAAVLLQGMTAHYLTFSTFPLKAGDTCLVHAAAGGVGLLLIQIARR
LGARVIGTVSTDEKAELARAAGADEVVIYTRESFVERVRAFTNGRGVDVVYDSVGASTLEGSLDSLRPRGMFVTFGNASG
PLPPISPLLLSSKGSLFMTRPTLFHYIATPEELRWRASDLFTWIGAGELQVRIHRRYPLSEAAEAQIALASRATTGKLLL
IP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=326, Percent_Identity=35.8895705521472, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI13236495, Length=326, Percent_Identity=35.8895705521472, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI194239676, Length=326, Percent_Identity=34.3558282208589, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI22538446, Length=331, Percent_Identity=30.5135951661631, Blast_Score=138, Evalue=5e-33,
Organism=Homo sapiens, GI22538444, Length=331, Percent_Identity=30.5135951661631, Blast_Score=138, Evalue=5e-33,
Organism=Homo sapiens, GI18379349, Length=312, Percent_Identity=31.4102564102564, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI24308257, Length=244, Percent_Identity=30.327868852459, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI28557745, Length=235, Percent_Identity=34.0425531914894, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI197927207, Length=193, Percent_Identity=30.5699481865285, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI41872631, Length=224, Percent_Identity=33.4821428571429, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI47519420, Length=336, Percent_Identity=24.1071428571429, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI67078404, Length=245, Percent_Identity=27.3469387755102, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790485, Length=323, Percent_Identity=45.8204334365325, Blast_Score=266, Evalue=1e-72,
Organism=Escherichia coli, GI1787863, Length=294, Percent_Identity=29.2517006802721, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI226510941, Length=327, Percent_Identity=24.7706422018349, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788073, Length=241, Percent_Identity=25.3112033195021, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=239, Percent_Identity=30.9623430962343, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17536829, Length=308, Percent_Identity=30.1948051948052, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71988145, Length=294, Percent_Identity=26.530612244898, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562584, Length=294, Percent_Identity=26.8707482993197, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17556000, Length=264, Percent_Identity=26.5151515151515, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=323, Percent_Identity=39.3188854489164, Blast_Score=235, Evalue=9e-63,
Organism=Saccharomyces cerevisiae, GI6323961, Length=267, Percent_Identity=30.3370786516854, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323729, Length=254, Percent_Identity=29.9212598425197, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324486, Length=258, Percent_Identity=30.2325581395349, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6319621, Length=266, Percent_Identity=30.0751879699248, Blast_Score=96, Evalue=6e-21,
Organism=Drosophila melanogaster, GI45550423, Length=337, Percent_Identity=26.1127596439169, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI19920632, Length=246, Percent_Identity=30.8943089430894, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221330659, Length=246, Percent_Identity=30.8943089430894, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581345, Length=271, Percent_Identity=28.4132841328413, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34293; Mature: 34293

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIQIHQTGGPEQLQMVDIPLPEPAPGQVRIKVAAAGVNFIDIYHRTGLYPQPLPFTLG
CCEEEEECCCCCCEEEEEECCCCCCCCCCEEEEEEECCCEEEEEHHHCCCCCCCCCEEEC
LEVAGTIDAVGEGVSEWAVGDRVGCTTASGGYAEYALAAADKLVRVPDNVDLETAAAVLL
EEEECCHHHHHCCHHHHCCCCCCCCEECCCCHHHHHHHHHHHEEECCCCCCHHHHHHHHH
QGMTAHYLTFSTFPLKAGDTCLVHAAAGGVGLLLIQIARRLGARVIGTVSTDEKAELARA
HCCCEEEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHH
AGADEVVIYTRESFVERVRAFTNGRGVDVVYDSVGASTLEGSLDSLRPRGMFVTFGNASG
CCCCEEEEEEHHHHHHHHHHHHCCCCEEEEEECCCCHHHCCCHHHCCCCEEEEEECCCCC
PLPPISPLLLSSKGSLFMTRPTLFHYIATPEELRWRASDLFTWIGAGELQVRIHRRYPLS
CCCCCCHHEECCCCCEEEECHHEEEEECCHHHHHHHHHHHEEEECCCEEEEEEEECCCCC
EAAEAQIALASRATTGKLLLIP
CHHHHEEEEEECCCCCEEEEEC
>Mature Secondary Structure
MRAIQIHQTGGPEQLQMVDIPLPEPAPGQVRIKVAAAGVNFIDIYHRTGLYPQPLPFTLG
CCEEEEECCCCCCEEEEEECCCCCCCCCCEEEEEEECCCEEEEEHHHCCCCCCCCCEEEC
LEVAGTIDAVGEGVSEWAVGDRVGCTTASGGYAEYALAAADKLVRVPDNVDLETAAAVLL
EEEECCHHHHHCCHHHHCCCCCCCCEECCCCHHHHHHHHHHHEEECCCCCCHHHHHHHHH
QGMTAHYLTFSTFPLKAGDTCLVHAAAGGVGLLLIQIARRLGARVIGTVSTDEKAELARA
HCCCEEEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHH
AGADEVVIYTRESFVERVRAFTNGRGVDVVYDSVGASTLEGSLDSLRPRGMFVTFGNASG
CCCCEEEEEEHHHHHHHHHHHHCCCCEEEEEECCCCHHHCCCHHHCCCCEEEEEECCCCC
PLPPISPLLLSSKGSLFMTRPTLFHYIATPEELRWRASDLFTWIGAGELQVRIHRRYPLS
CCCCCCHHEECCCCCEEEECHHEEEEECCHHHHHHHHHHHEEEECCCEEEEEEEECCCCC
EAAEAQIALASRATTGKLLLIP
CHHHHEEEEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]