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The map label for this gene is ubiB [C]

Identifier: 222525234

GI number: 222525234

Start: 2504930

End: 2506765

Strand: Direct

Name: ubiB [C]

Synonym: Chy400_1974

Alternate gene names: 222525234

Gene position: 2504930-2506765 (Clockwise)

Preceding gene: 222525232

Following gene: 222525236

Centisome position: 47.54

GC content: 57.68

Gene sequence:

>1836_bases
ATGCGTGAACCAATCTCTGTACAGGTAACTGATACCACCAACGCCGTTCCACGGCCAACCGAACCACCGCGCTTCCGTCC
GCGCGAGCGCTTCTTACGGGTCTCGTCGTTTTTTCTTGGCGTTGTCATTCACATCTACATCTGGGATATTTTTCTTGCCC
GCTTTGCCATCTTCCGCTGGTATGTTCAGCGCACCATGTTGCGGCGCTGGGTGTCTATTGCTCGCCGCTTCCGTATGATG
GCGGTTGAGCTTGGGGGCATGCAGATCAAGCTCGGTCAATTCCTCTCATCGCGGGCCGATATTATTCCCGATGTCGTGCG
CCGCGAGTTGACCGGTCTCCAGGATGAAGTGCCCCCCGCACCCGCCGGCCACGTGCTGGAGGTGATTTTAGAGGAACTCG
GTGCGCCACCCAGCGAGATCTTTCGCAGCTTTGAGACCGATTGTGTCGCCGCCGCATCGCTAGGACAGGTGCACTATGCC
GTGTTGCACGATGGCCGTGAGGTGGCGGTAAAGGTGCAACGCCCCTGGATAGATAAGATTGTCGAGGTCGATCTGAGCGC
AGTGACCTGGGTCGTGCGCCTGATCAAAAACTATCCGCCCATTCGCCGGCGTGCCGACCTGGAAGCGTTGCTGGCCGAAT
TTGCCCGTGTGCTCGTGCAGGAATTGGACTATGTGCAAGAGGCGCGTTCGGCAGCGACGTTCCGCCAGAACTTTGCTAAC
CATCCGGGGATTTACATTCCCGAACCGATCTTCGAGTTAACGACCCGGCGTGTGTTGGTGATGGAACGGATCAACGGGAT
TAAGATCACCGACCTGCATACCCTCGATCAGTTGGGTGTCAGTCGGGTTGAGCTGGCTGCCCGTTTGAACAATTGCTACC
TGAAACAGTTTTTCATTGACGGCTTCTTCCACGCTGATCCGCATCCCGGCAATCTCTTCGTGCGGGTAGAAACTGCGCTG
GCGCCCGTTCAGCCATCACCACCGGTAACATCGGTTAGTCGTAATGGCCACCTCTCGATGGATGCGGTTGAGGCCGGGCT
GCCGATTGACACTCCTCCAGATGAAGTGCCAGCCGGCACACCCTTCACGCTCATCTTTGTCGATTTCGGCATGGTTGGTC
GTCTGCCACCGCAAACGATGGAGATTATGCGGCAGGGTGTGTTGGGTCTGGCAACCAACGACGCCGACCGGATTCTGAAC
TGTCTCGAACAACTCAATATGATCCTGCCCGGTGCCGACCGGCGGGCAATCAAGACGGCTATCGAGACGATGTTGCGCTA
CTCGTTCAACCGCACCGTGCGCGAGCTGACCAACCTCGATGTCGAGGCGATTATGGCCGAGACGAAGGATTTAATTTACG
ATCTGCCTTTTCAGATTCCCCAAGACCTGCTCTATTTGGGGCGGGCGTTGAGCATGGTTGCCGGTCTCGCCACTGAGATT
TGCCCTGACATCAATCTGTTCCATGAGCTACGACCATTCGCACGAGCGATGCTGGCTCAAGAACAACGCAATGGCAATTG
GGTTGAGAAGTTGCAGCAAGAGCTAACTGAACTTGGTCAGATACTGATCGGGCTACCACGGCAGATGGATGCCTACTACC
GGGCGGCAAATCGGGGCGAATTGCAGACCCGTTCCGATCTGAGCCGGCTTGAACGCAGTATGAAACGGGTTGAGCGGGCG
ACTGACCGCTTGATGGGGGGAATGCTCGCAACCGGCCTGTTCCTCGGTGGCGTGCAGCTCCGCACTCGTGGTCTGGAACG
GGAAGCCAACCGGGCCTGGTGGGCCGCAGCAGCGGCGATTGTGTGGGCACTCTGGCCGCGCAACGAGCGCTGGTAG

Upstream 100 bases:

>100_bases
CCCGTTGTTATGGTAGTCGCCGATCAATTCGTTGCGGATCGGTCGTGAGATTGAGTTTCGCCTCTGGTATAATCAGTAAT
AGGAATACTGGCAGGATATT

Downstream 100 bases:

>100_bases
TGTTCTCCAACAGGTATAGGCTCAATCCCAGAGCAACATGAAGGCAACTACATCCAGTTGCCTTCATGTCACCACCCGTG
AGTCACTTAGTGACGCCAAC

Product: ABC-1 domain-containing protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MREPISVQVTDTTNAVPRPTEPPRFRPRERFLRVSSFFLGVVIHIYIWDIFLARFAIFRWYVQRTMLRRWVSIARRFRMM
AVELGGMQIKLGQFLSSRADIIPDVVRRELTGLQDEVPPAPAGHVLEVILEELGAPPSEIFRSFETDCVAAASLGQVHYA
VLHDGREVAVKVQRPWIDKIVEVDLSAVTWVVRLIKNYPPIRRRADLEALLAEFARVLVQELDYVQEARSAATFRQNFAN
HPGIYIPEPIFELTTRRVLVMERINGIKITDLHTLDQLGVSRVELAARLNNCYLKQFFIDGFFHADPHPGNLFVRVETAL
APVQPSPPVTSVSRNGHLSMDAVEAGLPIDTPPDEVPAGTPFTLIFVDFGMVGRLPPQTMEIMRQGVLGLATNDADRILN
CLEQLNMILPGADRRAIKTAIETMLRYSFNRTVRELTNLDVEAIMAETKDLIYDLPFQIPQDLLYLGRALSMVAGLATEI
CPDINLFHELRPFARAMLAQEQRNGNWVEKLQQELTELGQILIGLPRQMDAYYRAANRGELQTRSDLSRLERSMKRVERA
TDRLMGGMLATGLFLGGVQLRTRGLEREANRAWWAAAAAIVWALWPRNERW

Sequences:

>Translated_611_residues
MREPISVQVTDTTNAVPRPTEPPRFRPRERFLRVSSFFLGVVIHIYIWDIFLARFAIFRWYVQRTMLRRWVSIARRFRMM
AVELGGMQIKLGQFLSSRADIIPDVVRRELTGLQDEVPPAPAGHVLEVILEELGAPPSEIFRSFETDCVAAASLGQVHYA
VLHDGREVAVKVQRPWIDKIVEVDLSAVTWVVRLIKNYPPIRRRADLEALLAEFARVLVQELDYVQEARSAATFRQNFAN
HPGIYIPEPIFELTTRRVLVMERINGIKITDLHTLDQLGVSRVELAARLNNCYLKQFFIDGFFHADPHPGNLFVRVETAL
APVQPSPPVTSVSRNGHLSMDAVEAGLPIDTPPDEVPAGTPFTLIFVDFGMVGRLPPQTMEIMRQGVLGLATNDADRILN
CLEQLNMILPGADRRAIKTAIETMLRYSFNRTVRELTNLDVEAIMAETKDLIYDLPFQIPQDLLYLGRALSMVAGLATEI
CPDINLFHELRPFARAMLAQEQRNGNWVEKLQQELTELGQILIGLPRQMDAYYRAANRGELQTRSDLSRLERSMKRVERA
TDRLMGGMLATGLFLGGVQLRTRGLEREANRAWWAAAAAIVWALWPRNERW
>Mature_611_residues
MREPISVQVTDTTNAVPRPTEPPRFRPRERFLRVSSFFLGVVIHIYIWDIFLARFAIFRWYVQRTMLRRWVSIARRFRMM
AVELGGMQIKLGQFLSSRADIIPDVVRRELTGLQDEVPPAPAGHVLEVILEELGAPPSEIFRSFETDCVAAASLGQVHYA
VLHDGREVAVKVQRPWIDKIVEVDLSAVTWVVRLIKNYPPIRRRADLEALLAEFARVLVQELDYVQEARSAATFRQNFAN
HPGIYIPEPIFELTTRRVLVMERINGIKITDLHTLDQLGVSRVELAARLNNCYLKQFFIDGFFHADPHPGNLFVRVETAL
APVQPSPPVTSVSRNGHLSMDAVEAGLPIDTPPDEVPAGTPFTLIFVDFGMVGRLPPQTMEIMRQGVLGLATNDADRILN
CLEQLNMILPGADRRAIKTAIETMLRYSFNRTVRELTNLDVEAIMAETKDLIYDLPFQIPQDLLYLGRALSMVAGLATEI
CPDINLFHELRPFARAMLAQEQRNGNWVEKLQQELTELGQILIGLPRQMDAYYRAANRGELQTRSDLSRLERSMKRVERA
TDRLMGGMLATGLFLGGVQLRTRGLEREANRAWWAAAAAIVWALWPRNERW

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=242, Percent_Identity=33.0578512396694, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI41393593, Length=235, Percent_Identity=34.0425531914894, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI217035081, Length=184, Percent_Identity=34.2391304347826, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI27363457, Length=230, Percent_Identity=32.6086956521739, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI217416386, Length=199, Percent_Identity=34.1708542713568, Blast_Score=93, Evalue=8e-19,
Organism=Homo sapiens, GI32261307, Length=332, Percent_Identity=25, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI34147522, Length=234, Percent_Identity=29.4871794871795, Blast_Score=87, Evalue=5e-17,
Organism=Escherichia coli, GI2367309, Length=552, Percent_Identity=26.4492753623188, Blast_Score=168, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI17559152, Length=237, Percent_Identity=32.4894514767932, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI32565180, Length=230, Percent_Identity=31.7391304347826, Blast_Score=103, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6323282, Length=239, Percent_Identity=30.1255230125523, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6325148, Length=309, Percent_Identity=27.1844660194175, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6321319, Length=196, Percent_Identity=29.0816326530612, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24662575, Length=231, Percent_Identity=33.7662337662338, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI22024280, Length=231, Percent_Identity=32.9004329004329, Blast_Score=133, Evalue=5e-31,
Organism=Drosophila melanogaster, GI18859849, Length=229, Percent_Identity=27.9475982532751, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 69488; Mature: 69488

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREPISVQVTDTTNAVPRPTEPPRFRPRERFLRVSSFFLGVVIHIYIWDIFLARFAIFRW
CCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVQRTMLRRWVSIARRFRMMAVELGGMQIKLGQFLSSRADIIPDVVRRELTGLQDEVPPA
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PAGHVLEVILEELGAPPSEIFRSFETDCVAAASLGQVHYAVLHDGREVAVKVQRPWIDKI
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHH
VEVDLSAVTWVVRLIKNYPPIRRRADLEALLAEFARVLVQELDYVQEARSAATFRQNFAN
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HPGIYIPEPIFELTTRRVLVMERINGIKITDLHTLDQLGVSRVELAARLNNCYLKQFFID
CCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCHHHHHHCHHHHHHHHHHHHHHHHHHHHH
GFFHADPHPGNLFVRVETALAPVQPSPPVTSVSRNGHLSMDAVEAGLPIDTPPDEVPAGT
HHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCC
PFTLIFVDFGMVGRLPPQTMEIMRQGVLGLATNDADRILNCLEQLNMILPGADRRAIKTA
CEEEEEEECCHHCCCCHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHH
IETMLRYSFNRTVRELTNLDVEAIMAETKDLIYDLPFQIPQDLLYLGRALSMVAGLATEI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
CPDINLFHELRPFARAMLAQEQRNGNWVEKLQQELTELGQILIGLPRQMDAYYRAANRGE
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
LQTRSDLSRLERSMKRVERATDRLMGGMLATGLFLGGVQLRTRGLEREANRAWWAAAAAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHH
VWALWPRNERW
HHHHCCCCCCC
>Mature Secondary Structure
MREPISVQVTDTTNAVPRPTEPPRFRPRERFLRVSSFFLGVVIHIYIWDIFLARFAIFRW
CCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVQRTMLRRWVSIARRFRMMAVELGGMQIKLGQFLSSRADIIPDVVRRELTGLQDEVPPA
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PAGHVLEVILEELGAPPSEIFRSFETDCVAAASLGQVHYAVLHDGREVAVKVQRPWIDKI
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHH
VEVDLSAVTWVVRLIKNYPPIRRRADLEALLAEFARVLVQELDYVQEARSAATFRQNFAN
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HPGIYIPEPIFELTTRRVLVMERINGIKITDLHTLDQLGVSRVELAARLNNCYLKQFFID
CCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCHHHHHHCHHHHHHHHHHHHHHHHHHHHH
GFFHADPHPGNLFVRVETALAPVQPSPPVTSVSRNGHLSMDAVEAGLPIDTPPDEVPAGT
HHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCC
PFTLIFVDFGMVGRLPPQTMEIMRQGVLGLATNDADRILNCLEQLNMILPGADRRAIKTA
CEEEEEEECCHHCCCCHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHH
IETMLRYSFNRTVRELTNLDVEAIMAETKDLIYDLPFQIPQDLLYLGRALSMVAGLATEI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
CPDINLFHELRPFARAMLAQEQRNGNWVEKLQQELTELGQILIGLPRQMDAYYRAANRGE
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
LQTRSDLSRLERSMKRVERATDRLMGGMLATGLFLGGVQLRTRGLEREANRAWWAAAAAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHH
VWALWPRNERW
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]