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The map label for this gene is htpX1 [H]

Identifier: 222525013

GI number: 222525013

Start: 2208876

End: 2209769

Strand: Direct

Name: htpX1 [H]

Synonym: Chy400_1748

Alternate gene names: 222525013

Gene position: 2208876-2209769 (Clockwise)

Preceding gene: 222525012

Following gene: 222525014

Centisome position: 41.92

GC content: 57.61

Gene sequence:

>894_bases
GTGACAATGCTGGTAAATAGTTTGAAGACCGTTGGTTTGCTTGGACTGCTCACCGGTCTCTTCATCATGATTGGTGGTGC
AATTGGTGGTCAGATTGGGATGATCATCGCGCTCGTTCTGGCTGTCGTGATGAATATGGGTGCCTGGTGGTTCTCCGACA
AACTGGCACTCAAGATGAGCGGTGCGCAGGAAGTGACACCCGATCAGGCACCTGAGCTTCATGCGATGGTGGAAGAGCTA
TCACGGCGGGCTGGTATTCCCAAACCGCGCGTGTACATCATCGAAACTGACGCTCCCAACGCCTTTGCTACCGGTCGTGA
TCCGGCGCACGGCGCAGTAGCCGTAACCACCGGGATTGCACGCCTGCTCACACGCGAGGAGCTGGCCGGCGTCATCGCAC
ACGAGCTGGCACACATCAAGCATCGTGACACCCTGATCTCATCCATCGCAGCCACTATTGCCGGTGCTATCGGTATGCTG
GCCGATATGGTGATGTGGAGCATGATCTTCGCCGGTTTCGGTGGTAATGATGAAGAAGAAGGTGGTGGCGTTGCCGGACT
GGTTGGTGGCATCCTGACGGCCATGCTGGCACCAATTATGGCCCTTATCATTCAGATGGCAATTTCGCGTTCGCGTGAGT
ACATGGCAGATGCCGGCGGCGCGCAGATTCTCGGCAATCCATTGCCGTTAGCCAGTGCCCTTGAGAAGCTGGAATGGGCT
GCTGGGCGGATGCCAATGGATGAAGCACGTCCGGCGACGGCACACATGTACATTGTCAATCCGGTGCTGGGTGGCCTGGC
CAGCCTCTTCCGCACCCACCCCGAAACCCACAAGCGTATCTCGCGCCTGCGTGCGATGGCCAATCGCAGTGGTAACACAG
CGATGGCGGCGTAA

Upstream 100 bases:

>100_bases
AGGAGAGGCCCCCCCTTTGGTAGAACGTTGCGATGCAATATACTGGCAGTGCGAAAACGACATCCTGTGCAGGATCGTAG
TATAAAGTGGAGGAACTGCC

Downstream 100 bases:

>100_bases
GTCACATCTGCGCAGCGCGTTGACATAGATTTCCTCCCTATTCCAGGCATCACTCAATGGCGAGTGGTGCCCTTTTTGCG
GTAGAATACTCTTGTCTGGA

Product: peptidase M48 Ste24p

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTMLVNSLKTVGLLGLLTGLFIMIGGAIGGQIGMIIALVLAVVMNMGAWWFSDKLALKMSGAQEVTPDQAPELHAMVEEL
SRRAGIPKPRVYIIETDAPNAFATGRDPAHGAVAVTTGIARLLTREELAGVIAHELAHIKHRDTLISSIAATIAGAIGML
ADMVMWSMIFAGFGGNDEEEGGGVAGLVGGILTAMLAPIMALIIQMAISRSREYMADAGGAQILGNPLPLASALEKLEWA
AGRMPMDEARPATAHMYIVNPVLGGLASLFRTHPETHKRISRLRAMANRSGNTAMAA

Sequences:

>Translated_297_residues
MTMLVNSLKTVGLLGLLTGLFIMIGGAIGGQIGMIIALVLAVVMNMGAWWFSDKLALKMSGAQEVTPDQAPELHAMVEEL
SRRAGIPKPRVYIIETDAPNAFATGRDPAHGAVAVTTGIARLLTREELAGVIAHELAHIKHRDTLISSIAATIAGAIGML
ADMVMWSMIFAGFGGNDEEEGGGVAGLVGGILTAMLAPIMALIIQMAISRSREYMADAGGAQILGNPLPLASALEKLEWA
AGRMPMDEARPATAHMYIVNPVLGGLASLFRTHPETHKRISRLRAMANRSGNTAMAA
>Mature_296_residues
TMLVNSLKTVGLLGLLTGLFIMIGGAIGGQIGMIIALVLAVVMNMGAWWFSDKLALKMSGAQEVTPDQAPELHAMVEELS
RRAGIPKPRVYIIETDAPNAFATGRDPAHGAVAVTTGIARLLTREELAGVIAHELAHIKHRDTLISSIAATIAGAIGMLA
DMVMWSMIFAGFGGNDEEEGGGVAGLVGGILTAMLAPIMALIIQMAISRSREYMADAGGAQILGNPLPLASALEKLEWAA
GRMPMDEARPATAHMYIVNPVLGGLASLFRTHPETHKRISRLRAMANRSGNTAMAA

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=291, Percent_Identity=31.2714776632302, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 31240; Mature: 31109

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.8 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMLVNSLKTVGLLGLLTGLFIMIGGAIGGQIGMIIALVLAVVMNMGAWWFSDKLALKMS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCEEEEC
GAQEVTPDQAPELHAMVEELSRRAGIPKPRVYIIETDAPNAFATGRDPAHGAVAVTTGIA
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHH
RLLTREELAGVIAHELAHIKHRDTLISSIAATIAGAIGMLADMVMWSMIFAGFGGNDEEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GGGVAGLVGGILTAMLAPIMALIIQMAISRSREYMADAGGAQILGNPLPLASALEKLEWA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHH
AGRMPMDEARPATAHMYIVNPVLGGLASLFRTHPETHKRISRLRAMANRSGNTAMAA
HCCCCHHHCCCCCEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TMLVNSLKTVGLLGLLTGLFIMIGGAIGGQIGMIIALVLAVVMNMGAWWFSDKLALKMS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCEEEEC
GAQEVTPDQAPELHAMVEELSRRAGIPKPRVYIIETDAPNAFATGRDPAHGAVAVTTGIA
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHH
RLLTREELAGVIAHELAHIKHRDTLISSIAATIAGAIGMLADMVMWSMIFAGFGGNDEEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GGGVAGLVGGILTAMLAPIMALIIQMAISRSREYMADAGGAQILGNPLPLASALEKLEWA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHH
AGRMPMDEARPATAHMYIVNPVLGGLASLFRTHPETHKRISRLRAMANRSGNTAMAA
HCCCCHHHCCCCCEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]