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The map label for this gene is rsbRA [H]

Identifier: 222524994

GI number: 222524994

Start: 2182746

End: 2183423

Strand: Direct

Name: rsbRA [H]

Synonym: Chy400_1729

Alternate gene names: 222524994

Gene position: 2182746-2183423 (Clockwise)

Preceding gene: 222524993

Following gene: 222524996

Centisome position: 41.43

GC content: 56.49

Gene sequence:

>678_bases
ATGACAGGGCAGTGGTTTGGGGTGTCAGGCCGACCACAAGTGGCGCCATCGGCGGGAGAAATTGTCATTGTTGGCATACT
TCTCTCGCTGGTCTTTGGATTAATTGGAGGCATTGGCACTCGCAGCGTGCGGCGGGCAATCGAACTGGCACAACAGGCTC
AATCTCAGGCTGAAAGCCTGGCCCGTCAGTTGAGCCAGGTTAATCAGGCTCTAGAGCTGCGTGTGGCCGAACGAACAGCG
GCGTTGCAGGCTGCACTGGCTGAAAGCGAACAACGTCAGGCAGCACTCACGACGGCGTTGCAAGAAAATGAACGGCAACG
GCGAGAAATACAGGCGCTGAGTGTACCGATTTTAGCGGTGCGTCATGACATGTTGGTGATGCCGCTGATTGGTGCACTCG
ATGGCGAACGGCTGTCGCTTGCGCAACAACGTGCACTCAACGCCATAGAGCAGCAGCGCACCCGTTTCCTGCTAGTCGAT
GTAACCGGTGTGCCGTTCATTGATCAGACGGCTGCTGATGGATTGATTGTTCTGGCGCGCAGTGTACGCCTCCTCGGTGC
ACGCCTGTACCTGATTGGAGTCAGTCCTGATGTTGCGCAGACGATGATCGGATTGGGGATCGAGCTGCAAGAGATTGGGG
TCGCCCGTGATCTTCGCGATGCGATTATGCGTCTGTAA

Upstream 100 bases:

>100_bases
ATTGGCCTGGTACCCATTTTTGCGTTGGTTGCAGTCATCACAGCGACCGATCGGGCAAGAACATCACGTTGTTTTTGCAG
TTGTGTTCGGGATTGCCGGT

Downstream 100 bases:

>100_bases
CACCGTTACTACAACGACCGGTACAACTCAAGATGCGCAGCAGCAATATTCTGCCAGTCAAAGCGACGGGCAGCCTGACG
AGCTGCTTCACTCAGCCGAA

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTGQWFGVSGRPQVAPSAGEIVIVGILLSLVFGLIGGIGTRSVRRAIELAQQAQSQAESLARQLSQVNQALELRVAERTA
ALQAALAESEQRQAALTTALQENERQRREIQALSVPILAVRHDMLVMPLIGALDGERLSLAQQRALNAIEQQRTRFLLVD
VTGVPFIDQTAADGLIVLARSVRLLGARLYLIGVSPDVAQTMIGLGIELQEIGVARDLRDAIMRL

Sequences:

>Translated_225_residues
MTGQWFGVSGRPQVAPSAGEIVIVGILLSLVFGLIGGIGTRSVRRAIELAQQAQSQAESLARQLSQVNQALELRVAERTA
ALQAALAESEQRQAALTTALQENERQRREIQALSVPILAVRHDMLVMPLIGALDGERLSLAQQRALNAIEQQRTRFLLVD
VTGVPFIDQTAADGLIVLARSVRLLGARLYLIGVSPDVAQTMIGLGIELQEIGVARDLRDAIMRL
>Mature_224_residues
TGQWFGVSGRPQVAPSAGEIVIVGILLSLVFGLIGGIGTRSVRRAIELAQQAQSQAESLARQLSQVNQALELRVAERTAA
LQAALAESEQRQAALTTALQENERQRREIQALSVPILAVRHDMLVMPLIGALDGERLSLAQQRALNAIEQQRTRFLLVDV
TGVPFIDQTAADGLIVLARSVRLLGARLYLIGVSPDVAQTMIGLGIELQEIGVARDLRDAIMRL

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 24314; Mature: 24183

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGQWFGVSGRPQVAPSAGEIVIVGILLSLVFGLIGGIGTRSVRRAIELAQQAQSQAESL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ARQLSQVNQALELRVAERTAALQAALAESEQRQAALTTALQENERQRREIQALSVPILAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHDMLVMPLIGALDGERLSLAQQRALNAIEQQRTRFLLVDVTGVPFIDQTAADGLIVLAR
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHCCHHHHHHH
SVRLLGARLYLIGVSPDVAQTMIGLGIELQEIGVARDLRDAIMRL
HHHHHHHEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TGQWFGVSGRPQVAPSAGEIVIVGILLSLVFGLIGGIGTRSVRRAIELAQQAQSQAESL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ARQLSQVNQALELRVAERTAALQAALAESEQRQAALTTALQENERQRREIQALSVPILAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHDMLVMPLIGALDGERLSLAQQRALNAIEQQRTRFLLVDVTGVPFIDQTAADGLIVLAR
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHCCHHHHHHH
SVRLLGARLYLIGVSPDVAQTMIGLGIELQEIGVARDLRDAIMRL
HHHHHHHEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]