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The map label for this gene is bioH [H]

Identifier: 222524917

GI number: 222524917

Start: 2082181

End: 2083038

Strand: Reverse

Name: bioH [H]

Synonym: Chy400_1651

Alternate gene names: 222524917

Gene position: 2083038-2082181 (Counterclockwise)

Preceding gene: 222524920

Following gene: 222524913

Centisome position: 39.53

GC content: 56.41

Gene sequence:

>858_bases
ATGGTTGCTGCATCGCCTTTACCACTCTTACCGGTGTCGCCCGACTACATCACCTGGCGCGGCCTGCCGATTGCCGTCTA
CCAGGCCGGTACCGGTCAACCCGTCCTGCTCATTCACAGCATTAATGCTGCTGCATCGGTGTTCGAGATGCGCGAACCAT
TTCAACGCCTGAGCCGGCATTTTGCCGTCCACGCGGTCGATCTGCCCGGATACGGCAATTCAGCGCGTCCGCCCTGGCGT
TATCGGGCTGCGGTGTATATCGATCTGATCACGACCATCCTCGAACGGATCGGTCAACCGGCTGCCCTGATTGCCAGTTC
ATTAGGCGCGGCGTATGCGGTGATGGCTACTGTGCGCCGCCCCGACCTGGTCAATCGCCTGGTGCTGATCTGTCCTACCG
GTATTGGTCAACTGGATCGTCCACCCGGTGTAGCAGCGTACACCCTCTACCAAATCCTCCGCAGCCCGATAGGTCGGCTG
CTGTATCGATTACTCACCACGCGGGCCAGCATTCGCCTTTTTCTCACCAGTCAGGCATACGCCGATCCGGCAAATGTTAC
TTCTGAACGTCTGCACGGTTTCTATCAGACATGCCGTCGCCCTGGTTCGTATTATGCACCGATCTGTTTTCTTAGTGGCC
TGCTTAACTGTAATATTGCCTCAGCCTTCGCGACCCTGACCCAACCGACTCTTCTGGTTTGGGGGAGTGATGCCACGACC
ACACCTTTGCGGTTGGCGGCCAGTTTCGTTCGGGTTCGGGTAGCAACAAAAGTGGTAGTGATTGATCGAGCCAGTTTGCT
GGTGCAGGATGAACAACCAGAAGCGTTTATAGAACAGGTTATGCCGTTTCTTTCCTGA

Upstream 100 bases:

>100_bases
GAGCAGCAATGGCGCTATCGTGCAGGTATCACGTGCTTGCTATTGGTAGCAGGCGTGAAGTCTAAAACTCCTGCTCTACG
TACATCACACAGGATACAGT

Downstream 100 bases:

>100_bases
CGGTTAAACATCGGAACTGTCGGTACCAAGGGGAGAGCGATGTTGCCTCTTCCCGGAATCTGGTTGAATAGAAGTTATAG
CACGCTGTCGCGCTGTACCT

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: Biotin synthesis protein BioH [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MVAASPLPLLPVSPDYITWRGLPIAVYQAGTGQPVLLIHSINAAASVFEMREPFQRLSRHFAVHAVDLPGYGNSARPPWR
YRAAVYIDLITTILERIGQPAALIASSLGAAYAVMATVRRPDLVNRLVLICPTGIGQLDRPPGVAAYTLYQILRSPIGRL
LYRLLTTRASIRLFLTSQAYADPANVTSERLHGFYQTCRRPGSYYAPICFLSGLLNCNIASAFATLTQPTLLVWGSDATT
TPLRLAASFVRVRVATKVVVIDRASLLVQDEQPEAFIEQVMPFLS

Sequences:

>Translated_285_residues
MVAASPLPLLPVSPDYITWRGLPIAVYQAGTGQPVLLIHSINAAASVFEMREPFQRLSRHFAVHAVDLPGYGNSARPPWR
YRAAVYIDLITTILERIGQPAALIASSLGAAYAVMATVRRPDLVNRLVLICPTGIGQLDRPPGVAAYTLYQILRSPIGRL
LYRLLTTRASIRLFLTSQAYADPANVTSERLHGFYQTCRRPGSYYAPICFLSGLLNCNIASAFATLTQPTLLVWGSDATT
TPLRLAASFVRVRVATKVVVIDRASLLVQDEQPEAFIEQVMPFLS
>Mature_285_residues
MVAASPLPLLPVSPDYITWRGLPIAVYQAGTGQPVLLIHSINAAASVFEMREPFQRLSRHFAVHAVDLPGYGNSARPPWR
YRAAVYIDLITTILERIGQPAALIASSLGAAYAVMATVRRPDLVNRLVLICPTGIGQLDRPPGVAAYTLYQILRSPIGRL
LYRLLTTRASIRLFLTSQAYADPANVTSERLHGFYQTCRRPGSYYAPICFLSGLLNCNIASAFATLTQPTLLVWGSDATT
TPLRLAASFVRVRVATKVVVIDRASLLVQDEQPEAFIEQVMPFLS

Specific function: Shows carboxylesterase activity with a preference for short chain fatty acid esters (acyl chain length of up to 6 carbons). Also displays a weak thioesterase activity. Can form a complex with CoA, and may be involved in the condensation of CoA and pimelic

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010076 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 31238; Mature: 31238

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAASPLPLLPVSPDYITWRGLPIAVYQAGTGQPVLLIHSINAAASVFEMREPFQRLSRH
CCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
FAVHAVDLPGYGNSARPPWRYRAAVYIDLITTILERIGQPAALIASSLGAAYAVMATVRR
HEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
PDLVNRLVLICPTGIGQLDRPPGVAAYTLYQILRSPIGRLLYRLLTTRASIRLFLTSQAY
CHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
ADPANVTSERLHGFYQTCRRPGSYYAPICFLSGLLNCNIASAFATLTQPTLLVWGSDATT
CCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCCC
TPLRLAASFVRVRVATKVVVIDRASLLVQDEQPEAFIEQVMPFLS
HHHHHHHHHHHHHHHHEEEEEECCEEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MVAASPLPLLPVSPDYITWRGLPIAVYQAGTGQPVLLIHSINAAASVFEMREPFQRLSRH
CCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
FAVHAVDLPGYGNSARPPWRYRAAVYIDLITTILERIGQPAALIASSLGAAYAVMATVRR
HEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
PDLVNRLVLICPTGIGQLDRPPGVAAYTLYQILRSPIGRLLYRLLTTRASIRLFLTSQAY
CHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
ADPANVTSERLHGFYQTCRRPGSYYAPICFLSGLLNCNIASAFATLTQPTLLVWGSDATT
CCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCCC
TPLRLAASFVRVRVATKVVVIDRASLLVQDEQPEAFIEQVMPFLS
HHHHHHHHHHHHHHHHEEEEEECCEEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA