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The map label for this gene is mpg1 [H]

Identifier: 222524869

GI number: 222524869

Start: 2027223

End: 2028926

Strand: Reverse

Name: mpg1 [H]

Synonym: Chy400_1596

Alternate gene names: 222524869

Gene position: 2028926-2027223 (Counterclockwise)

Preceding gene: 222524870

Following gene: 222524868

Centisome position: 38.51

GC content: 56.34

Gene sequence:

>1704_bases
ATGACTATTGCTTTCATCATTGCTACGGCTGAAGAGCGTCGGTTGGCCCCCTTAACCGACGTTGCACCTGATGTGTTATT
ACCGATTGTTGACCGCCCGGTGATGGCGACCACGATTGAAATTCTGGCCCGCGCCGGTATCAAACGTATTCTGATTGCGC
TCCACGAACAGAGTGCTCCCATTACTGCGGTGTTCGGTAGTGGCAGACGTTGGGGTGTTGATATCGAGTACGTTTCACTG
AACGAAGCGTGGGCAGATGGCGGTGCGCTGCGCTGGGCAGCGCCCCTTATTCACGAGACCTGTCTGGTCATTCCGGGAAA
CGCGATTATTGATGTTGCGATAGAAGCAGCGCTTGATCATCACCAGCGGCAGGGAGCACTGCTGACGGCGATTACCCATC
AACCTCACCCGCATCAGGCCACACCATATGCCGTGGTCGCGGCTGATGGTCAGATCGGTGCCGTGCTCGAAACACCAACC
GGGGCTGATGTCGTTGCCCTTACCGGAGCGTATATTGTTGAGCCGGCGCTGATTGAACACATCCCGCTGCGCAGTCGTTG
TGTTATCGCCACCGATCTGCTACCGCGCTTGATTGCCGGGCAAACACCGGTACAGAATTTTACCTTCAGCGGTTACTGGA
ATCCGCTCACGACACTGACCGACTATTACGCAGCTCAACAGGTCTTCCTCTACAGCGCCTATCGAGCACTTGATCCCAAC
CTCACCGACGGACCTGCGGACACGGTTCGCTACCCTTCGCTCAGCGGACGCAAAATTGCCCCAGGCATCTGGGTTGGGCG
TAACGATTCGATCCATCCGAGTGTACGGATTGCGCCCCCCCTGTACATTGGCGACAACTGCTGGATCGGGCGTGAGGCTG
AACTCGGCACGGGAACGGTCATCGGTAGCGGTTGTATGGTCGATGATGAAGCCACCGTCACGGCCAGTATTGTGTGGAGC
GACACCTACGTGGGACAACTGGTCAATCTCAATCAACGGATTGTCTATCCTGGGATGATTGTAGACCCGGATACCGGTGA
GCAGACGGCAATTGTCGACGCCTTTCTCATCGGGCGGGTTTCAGCAGTGACCGCTAGCGTTGGGCGATTTGCCAGTTTCC
TGAATCGGCTCGCTGCGCTTCTGCTCTTGATCCTGCTCAGCCCATTGTTTTTACTGACGGGTATCCTGGCTGCTCTGGGG
AGTGGTGGACGACCACTGGTGGGGGTCGCACGGATTGGTGAACGAATTATCTTGCCTGATGGTCACATGACTCTGCGGCC
TTTCACACTCTGGCGCTGGCACACGCGCCACGCAGACGGGCGCTACCGCTGGTTTGGTAGATGGCTGGAAACGTATGAAT
TGCATCGTTTACCAGAACTCTTAAGTGTCCTGCGTGGCGACTTGCAACTGGTCGGCGTCAAACCCCTGACACCAAATGAG
GCAGCGCTGTTAAACGAAGAGTGGCAGCAGCGACGGCACGATGTGCCGCCTGGAGTGACCGGTTTGTGGTATGTTCAGGC
TTCATCCGATGATCTCGATACAGTGATTATTGCCGATGTATACTATAGCGCGACACGCTCGTGGCGAAGAGACCTTGACC
TGTTGGTTCGGACCCCGGTTGCCTGGCTACGCCGGGTAACAAAGGCGCATCAGACTGTCAGATCGTCATTGACACCCGAT
CTGACCCTGCCACCTAACCGATAG

Upstream 100 bases:

>100_bases
GTACGCCTCGATCAGGTCTTACACATCTTTCCAGATGTCACGGCGGCAACAACGGCACCTTTGCCTGACACCTCTGTAGC
CACTGAAGGAGCCTGAACCG

Downstream 100 bases:

>100_bases
GTCAGTTTGTCGCCGTCACTAACCGGCAGTTTGCGCTACTTAAGGAGGATTTAGACTATGGAAATGAAGCCACGGATGGT
CGGGAATGTGGCAGTCCTTG

Product: nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MTIAFIIATAEERRLAPLTDVAPDVLLPIVDRPVMATTIEILARAGIKRILIALHEQSAPITAVFGSGRRWGVDIEYVSL
NEAWADGGALRWAAPLIHETCLVIPGNAIIDVAIEAALDHHQRQGALLTAITHQPHPHQATPYAVVAADGQIGAVLETPT
GADVVALTGAYIVEPALIEHIPLRSRCVIATDLLPRLIAGQTPVQNFTFSGYWNPLTTLTDYYAAQQVFLYSAYRALDPN
LTDGPADTVRYPSLSGRKIAPGIWVGRNDSIHPSVRIAPPLYIGDNCWIGREAELGTGTVIGSGCMVDDEATVTASIVWS
DTYVGQLVNLNQRIVYPGMIVDPDTGEQTAIVDAFLIGRVSAVTASVGRFASFLNRLAALLLLILLSPLFLLTGILAALG
SGGRPLVGVARIGERIILPDGHMTLRPFTLWRWHTRHADGRYRWFGRWLETYELHRLPELLSVLRGDLQLVGVKPLTPNE
AALLNEEWQQRRHDVPPGVTGLWYVQASSDDLDTVIIADVYYSATRSWRRDLDLLVRTPVAWLRRVTKAHQTVRSSLTPD
LTLPPNR

Sequences:

>Translated_567_residues
MTIAFIIATAEERRLAPLTDVAPDVLLPIVDRPVMATTIEILARAGIKRILIALHEQSAPITAVFGSGRRWGVDIEYVSL
NEAWADGGALRWAAPLIHETCLVIPGNAIIDVAIEAALDHHQRQGALLTAITHQPHPHQATPYAVVAADGQIGAVLETPT
GADVVALTGAYIVEPALIEHIPLRSRCVIATDLLPRLIAGQTPVQNFTFSGYWNPLTTLTDYYAAQQVFLYSAYRALDPN
LTDGPADTVRYPSLSGRKIAPGIWVGRNDSIHPSVRIAPPLYIGDNCWIGREAELGTGTVIGSGCMVDDEATVTASIVWS
DTYVGQLVNLNQRIVYPGMIVDPDTGEQTAIVDAFLIGRVSAVTASVGRFASFLNRLAALLLLILLSPLFLLTGILAALG
SGGRPLVGVARIGERIILPDGHMTLRPFTLWRWHTRHADGRYRWFGRWLETYELHRLPELLSVLRGDLQLVGVKPLTPNE
AALLNEEWQQRRHDVPPGVTGLWYVQASSDDLDTVIIADVYYSATRSWRRDLDLLVRTPVAWLRRVTKAHQTVRSSLTPD
LTLPPNR
>Mature_566_residues
TIAFIIATAEERRLAPLTDVAPDVLLPIVDRPVMATTIEILARAGIKRILIALHEQSAPITAVFGSGRRWGVDIEYVSLN
EAWADGGALRWAAPLIHETCLVIPGNAIIDVAIEAALDHHQRQGALLTAITHQPHPHQATPYAVVAADGQIGAVLETPTG
ADVVALTGAYIVEPALIEHIPLRSRCVIATDLLPRLIAGQTPVQNFTFSGYWNPLTTLTDYYAAQQVFLYSAYRALDPNL
TDGPADTVRYPSLSGRKIAPGIWVGRNDSIHPSVRIAPPLYIGDNCWIGREAELGTGTVIGSGCMVDDEATVTASIVWSD
TYVGQLVNLNQRIVYPGMIVDPDTGEQTAIVDAFLIGRVSAVTASVGRFASFLNRLAALLLLILLSPLFLLTGILAALGS
GGRPLVGVARIGERIILPDGHMTLRPFTLWRWHTRHADGRYRWFGRWLETYELHRLPELLSVLRGDLQLVGVKPLTPNEA
ALLNEEWQQRRHDVPPGVTGLWYVQASSDDLDTVIIADVYYSATRSWRRDLDLLVRTPVAWLRRVTKAHQTVRSSLTPDL
TLPPNR

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=364, Percent_Identity=22.5274725274725, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI11761619, Length=299, Percent_Identity=24.4147157190635, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI133931050, Length=351, Percent_Identity=23.9316239316239, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320148, Length=329, Percent_Identity=22.7963525835866, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 62154; Mature: 62023

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAFIIATAEERRLAPLTDVAPDVLLPIVDRPVMATTIEILARAGIKRILIALHEQSAP
CEEEEEEEECCCCCCCCHHHCCHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCC
ITAVFGSGRRWGVDIEYVSLNEAWADGGALRWAAPLIHETCLVIPGNAIIDVAIEAALDH
EEEEECCCCEECEEEEEEECCHHHCCCCCEEHHHHHHHCEEEEECCCCEEHHHHHHHHHH
HQRQGALLTAITHQPHPHQATPYAVVAADGQIGAVLETPTGADVVALTGAYIVEPALIEH
HHHCCCEEEEEECCCCCCCCCCEEEEEECCCEEEEEECCCCCCEEEECCHHHHCHHHHHC
IPLRSRCVIATDLLPRLIAGQTPVQNFTFSGYWNPLTTLTDYYAAQQVFLYSAYRALDPN
CCCCCCEEEHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
LTDGPADTVRYPSLSGRKIAPGIWVGRNDSIHPSVRIAPPLYIGDNCWIGREAELGTGTV
CCCCCCCCEECCCCCCCEECCEEEECCCCCCCCCEEECCCEEECCCCEECCCCCCCCCEE
IGSGCMVDDEATVTASIVWSDTYVGQLVNLNQRIVYPGMIVDPDTGEQTAIVDAFLIGRV
EECCEEECCCCEEEEEEEECCHHHHHHHCCCCEEEECCEEECCCCCCCHHHHHHHHHHHH
SAVTASVGRFASFLNRLAALLLLILLSPLFLLTGILAALGSGGRPLVGVARIGERIILPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHCCCEEEECC
GHMTLRPFTLWRWHTRHADGRYRWFGRWLETYELHRLPELLSVLRGDLQLVGVKPLTPNE
CCEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCH
AALLNEEWQQRRHDVPPGVTGLWYVQASSDDLDTVIIADVYYSATRSWRRDLDLLVRTPV
HHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCHH
AWLRRVTKAHQTVRSSLTPDLTLPPNR
HHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TIAFIIATAEERRLAPLTDVAPDVLLPIVDRPVMATTIEILARAGIKRILIALHEQSAP
EEEEEEEECCCCCCCCHHHCCHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCC
ITAVFGSGRRWGVDIEYVSLNEAWADGGALRWAAPLIHETCLVIPGNAIIDVAIEAALDH
EEEEECCCCEECEEEEEEECCHHHCCCCCEEHHHHHHHCEEEEECCCCEEHHHHHHHHHH
HQRQGALLTAITHQPHPHQATPYAVVAADGQIGAVLETPTGADVVALTGAYIVEPALIEH
HHHCCCEEEEEECCCCCCCCCCEEEEEECCCEEEEEECCCCCCEEEECCHHHHCHHHHHC
IPLRSRCVIATDLLPRLIAGQTPVQNFTFSGYWNPLTTLTDYYAAQQVFLYSAYRALDPN
CCCCCCEEEHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
LTDGPADTVRYPSLSGRKIAPGIWVGRNDSIHPSVRIAPPLYIGDNCWIGREAELGTGTV
CCCCCCCCEECCCCCCCEECCEEEECCCCCCCCCEEECCCEEECCCCEECCCCCCCCCEE
IGSGCMVDDEATVTASIVWSDTYVGQLVNLNQRIVYPGMIVDPDTGEQTAIVDAFLIGRV
EECCEEECCCCEEEEEEEECCHHHHHHHCCCCEEEECCEEECCCCCCCHHHHHHHHHHHH
SAVTASVGRFASFLNRLAALLLLILLSPLFLLTGILAALGSGGRPLVGVARIGERIILPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHCCCEEEECC
GHMTLRPFTLWRWHTRHADGRYRWFGRWLETYELHRLPELLSVLRGDLQLVGVKPLTPNE
CCEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCH
AALLNEEWQQRRHDVPPGVTGLWYVQASSDDLDTVIIADVYYSATRSWRRDLDLLVRTPV
HHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCHH
AWLRRVTKAHQTVRSSLTPDLTLPPNR
HHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]