Click here to switch to the map view.

The map label for this gene is fabZ

Identifier: 222524828

GI number: 222524828

Start: 1977259

End: 1977693

Strand: Direct

Name: fabZ

Synonym: Chy400_1555

Alternate gene names: 222524828

Gene position: 1977259-1977693 (Clockwise)

Preceding gene: 222524827

Following gene: 222524830

Centisome position: 37.53

GC content: 58.85

Gene sequence:

>435_bases
ATGCTGTCAATTCAAGAGATCATGGCGCTCATTCCTCACCGCTACCCCTTTCTCCTTGTTGACCGGATTATGGAGCTAGA
GCCGGGTGTGCGTGCGGTAGGTGAAAAGCTGGTATCGGCCAATGAACCATACTTTCAGGGGCATTTTCCCGGCAATCCGA
TCATGCCCGGTGTGCTGATACTGGAAGCACTGGCCCAAACCGGGGCAGTGGCTGCTCTGAGTGCACCGGAAAACGCCGGC
AAGCTGGTGCTCTTTGCCGGTATCGATGGCGCACGCTTCAAGCGCGTGGTGCGACCTGGCGATACGTTGCGTCTGGAAGT
GCAACTGGAGAAGATGCGGCGTGGAGTCGGTAAAGGCCAGGCCCGCGCTACGGTCGCCGATCAACTGGCCTGCGAGGCCG
AATTGCTCTTTGCGCTGACCGATCCTTCGCGCTAG

Upstream 100 bases:

>100_bases
GTTACGATCTCGAACCATACTCGTCAGGCAGTCCGCGTCTGATTGCCGTTGCTTCTCCCCGGCGCTAAGCTGCGCCTGTA
GTCTGAAGGAGTCTTGTGTT

Downstream 100 bases:

>100_bases
CAAGGTATGGGTTTGCGACTGGACGGCTTACGAATGTCTGTCTTTGAGAATTGACTCAAGCTACCTGTATCAAAGCGCCG
ATAGCGTGCGCGTCGGTTAT

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MLSIQEIMALIPHRYPFLLVDRIMELEPGVRAVGEKLVSANEPYFQGHFPGNPIMPGVLILEALAQTGAVAALSAPENAG
KLVLFAGIDGARFKRVVRPGDTLRLEVQLEKMRRGVGKGQARATVADQLACEAELLFALTDPSR

Sequences:

>Translated_144_residues
MLSIQEIMALIPHRYPFLLVDRIMELEPGVRAVGEKLVSANEPYFQGHFPGNPIMPGVLILEALAQTGAVAALSAPENAG
KLVLFAGIDGARFKRVVRPGDTLRLEVQLEKMRRGVGKGQARATVADQLACEAELLFALTDPSR
>Mature_144_residues
MLSIQEIMALIPHRYPFLLVDRIMELEPGVRAVGEKLVSANEPYFQGHFPGNPIMPGVLILEALAQTGAVAALSAPENAG
KLVLFAGIDGARFKRVVRPGDTLRLEVQLEKMRRGVGKGQARATVADQLACEAELLFALTDPSR

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=141, Percent_Identity=55.3191489361702, Blast_Score=142, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_CHLAA (A9WAA2)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001635050.1
- ProteinModelPortal:   A9WAA2
- SMR:   A9WAA2
- GeneID:   5828539
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_1433
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 15604; Mature: 15604

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: ACT_SITE 48-48

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIQEIMALIPHRYPFLLVDRIMELEPGVRAVGEKLVSANEPYFQGHFPGNPIMPGVLI
CCCHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEECCCCCCCCCHHHHH
LEALAQTGAVAALSAPENAGKLVLFAGIDGARFKRVVRPGDTLRLEVQLEKMRRGVGKGQ
HHHHHHCCCEEEECCCCCCCCEEEEECCCCHHHHHHCCCCCEEEEEEEHHHHHCCCCCCC
ARATVADQLACEAELLFALTDPSR
HHHHHHHHHHHCEEEEEEECCCCC
>Mature Secondary Structure
MLSIQEIMALIPHRYPFLLVDRIMELEPGVRAVGEKLVSANEPYFQGHFPGNPIMPGVLI
CCCHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEECCCCCCCCCHHHHH
LEALAQTGAVAALSAPENAGKLVLFAGIDGARFKRVVRPGDTLRLEVQLEKMRRGVGKGQ
HHHHHHCCCEEEECCCCCCCCEEEEECCCCHHHHHHCCCCCEEEEEEEHHHHHCCCCCCC
ARATVADQLACEAELLFALTDPSR
HHHHHHHHHHHCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA