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The map label for this gene is asnC

Identifier: 222524823

GI number: 222524823

Start: 1969260

End: 1970582

Strand: Reverse

Name: asnC

Synonym: Chy400_1550

Alternate gene names: 222524823

Gene position: 1970582-1969260 (Counterclockwise)

Preceding gene: 222524829

Following gene: 222524815

Centisome position: 37.4

GC content: 55.71

Gene sequence:

>1323_bases
ATGTCGCTGTTGCCAACTGCAACCGTTGCGACCATTGCCCGTTACGTTGGTCAGCGCGTTACTCTGGCCGGCTGGGTCTA
CCACAAGACCGAGAAAGGTAAACTGATCTTTATTCTCTTGCGCGACGGTAGTGGAACAATTCAATGTGTCACATTTAAGA
AAAACGTCAGTGAAGAGACCTTTGCTACCGCACAATCACTCACCCAAGAGAGTTCTTGTCGTATCACCGGCAGCGTGCGA
GCCGACGAGCGAGCGCCGGGTGGGTACGAACTTGATGTTGAGTCAATTGAACTCATTGGCCCTAGCCACGAATATCCAAT
CACTCCCAAAGAGCACGGGGTTGAATTTCTGATGGCACACCGCCACCTGTGGGTACGTTCGGCGAAGCAGCACGCCATCC
TACGGATTCGGGCCGAGGTCATTGCCGCTGCCCAGGAGTGGTTGAACGAGCAGGGGTTTGTGCGCTTCGACACCCCGATC
CTAACCGCGACTGCGGCTGAAGGCACCACAAATCTGTTTGCAACCGACTATTTCGATCTGGGCAAAGCGTATCTGGCCCA
GACCGGTCAACTCTACGTTGAAGCCGGTATGATGGCGTTTGGGAAGGTATACTGCTTTGGCCCAACCTTCCGCGCCGAGA
AGAGCAAGACTCGCCGGCATCTAACCGAATTCTGGATGATCGAGCCGGAAGTAGCCTTCGCCGATCACGAAGACAACATG
CGTCTTCAAGAGGAATTTGTCAGCGCAATTGTGGCCCGTGTGCTGGAGCGGCGACGAGACGATTTGCAGACCCTGGAGCG
TGACACGACCCTGCTCGAACAGGTACGACCGCCGTTTCCGCGGATTACCTACGATGAGGCTATCGAGTTGATCGCTGCGC
ACCAGGGGGAAGTGGAAGGTGCCGACCCATTGCCGTGGGGCGAAGATTTCGGTGCTCCTCACGAAACCTTGATTGCCTCG
AAGTTTGATCGCCCGGTCTTCGTTGAACGTTTCCCATCGGCGGTTAAGGCCTTCTACATGCAACCGGACCCGGAACGCCC
AGAAGTTGCGTTGTGTGCCGATCTGTTGGCTCCGGAGGGATACGGTGAGATTATCGGTGGTTCACAGCGCATTCACGACC
CGATCCTTCTCGAGCAACGCATCCGTGAACACGGTCTGCGCATTGAAGACTACGAGTGGTATCTCGATCTCCGCCGCTAT
GGGACAGTGCCACACAGTGGCTTTGGCATGGGCATTGAGCGCGTCGTAGCCTGGATTACCGGCACTCGCCACATTCGGGA
AACAATACCGTTCCCACGCCAACTGTATCGCATCTATCCATAA

Upstream 100 bases:

>100_bases
GTGGCCTGGGCGAACACCTGCCGACCAATTTGCCAGCTATGCCAGATCGTGGCATACTGACGCTGTAGAAAGACAAGACA
GATAGCGATAAGGAGCGTCT

Downstream 100 bases:

>100_bases
AGGAGATACGACCGGTAGAGCTACTTCCATCAAGCAGCCAGACACAATAATCAGCGCGGAGGGGAAAGGAGTGTTCCCCT
CCGCGCTGACTGTTTTAGCT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSLLPTATVATIARYVGQRVTLAGWVYHKTEKGKLIFILLRDGSGTIQCVTFKKNVSEETFATAQSLTQESSCRITGSVR
ADERAPGGYELDVESIELIGPSHEYPITPKEHGVEFLMAHRHLWVRSAKQHAILRIRAEVIAAAQEWLNEQGFVRFDTPI
LTATAAEGTTNLFATDYFDLGKAYLAQTGQLYVEAGMMAFGKVYCFGPTFRAEKSKTRRHLTEFWMIEPEVAFADHEDNM
RLQEEFVSAIVARVLERRRDDLQTLERDTTLLEQVRPPFPRITYDEAIELIAAHQGEVEGADPLPWGEDFGAPHETLIAS
KFDRPVFVERFPSAVKAFYMQPDPERPEVALCADLLAPEGYGEIIGGSQRIHDPILLEQRIREHGLRIEDYEWYLDLRRY
GTVPHSGFGMGIERVVAWITGTRHIRETIPFPRQLYRIYP

Sequences:

>Translated_440_residues
MSLLPTATVATIARYVGQRVTLAGWVYHKTEKGKLIFILLRDGSGTIQCVTFKKNVSEETFATAQSLTQESSCRITGSVR
ADERAPGGYELDVESIELIGPSHEYPITPKEHGVEFLMAHRHLWVRSAKQHAILRIRAEVIAAAQEWLNEQGFVRFDTPI
LTATAAEGTTNLFATDYFDLGKAYLAQTGQLYVEAGMMAFGKVYCFGPTFRAEKSKTRRHLTEFWMIEPEVAFADHEDNM
RLQEEFVSAIVARVLERRRDDLQTLERDTTLLEQVRPPFPRITYDEAIELIAAHQGEVEGADPLPWGEDFGAPHETLIAS
KFDRPVFVERFPSAVKAFYMQPDPERPEVALCADLLAPEGYGEIIGGSQRIHDPILLEQRIREHGLRIEDYEWYLDLRRY
GTVPHSGFGMGIERVVAWITGTRHIRETIPFPRQLYRIYP
>Mature_439_residues
SLLPTATVATIARYVGQRVTLAGWVYHKTEKGKLIFILLRDGSGTIQCVTFKKNVSEETFATAQSLTQESSCRITGSVRA
DERAPGGYELDVESIELIGPSHEYPITPKEHGVEFLMAHRHLWVRSAKQHAILRIRAEVIAAAQEWLNEQGFVRFDTPIL
TATAAEGTTNLFATDYFDLGKAYLAQTGQLYVEAGMMAFGKVYCFGPTFRAEKSKTRRHLTEFWMIEPEVAFADHEDNMR
LQEEFVSAIVARVLERRRDDLQTLERDTTLLEQVRPPFPRITYDEAIELIAAHQGEVEGADPLPWGEDFGAPHETLIASK
FDRPVFVERFPSAVKAFYMQPDPERPEVALCADLLAPEGYGEIIGGSQRIHDPILLEQRIREHGLRIEDYEWYLDLRRYG
TVPHSGFGMGIERVVAWITGTRHIRETIPFPRQLYRIYP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI4758762, Length=444, Percent_Identity=33.1081081081081, Blast_Score=251, Evalue=9e-67,
Organism=Homo sapiens, GI226491502, Length=442, Percent_Identity=35.0678733031674, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI45439306, Length=449, Percent_Identity=30.7349665924276, Blast_Score=188, Evalue=7e-48,
Organism=Escherichia coli, GI1787161, Length=467, Percent_Identity=37.6873661670236, Blast_Score=277, Evalue=9e-76,
Organism=Escherichia coli, GI1788173, Length=229, Percent_Identity=31.0043668122271, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71984122, Length=454, Percent_Identity=36.3436123348018, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17551876, Length=454, Percent_Identity=28.4140969162996, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17556372, Length=420, Percent_Identity=30.7142857142857, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32566633, Length=307, Percent_Identity=25.7328990228013, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321807, Length=441, Percent_Identity=34.2403628117914, Blast_Score=249, Evalue=8e-67,
Organism=Saccharomyces cerevisiae, GI6319872, Length=457, Percent_Identity=30.1969365426696, Blast_Score=196, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6323011, Length=334, Percent_Identity=35.0299401197605, Blast_Score=166, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6325153, Length=303, Percent_Identity=28.0528052805281, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI19921528, Length=432, Percent_Identity=34.7222222222222, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI19922416, Length=446, Percent_Identity=30.9417040358744, Blast_Score=214, Evalue=9e-56,
Organism=Drosophila melanogaster, GI17136276, Length=465, Percent_Identity=30.1075268817204, Blast_Score=184, Evalue=1e-46,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_CHLAA (A9WA97)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001635045.1
- ProteinModelPortal:   A9WA97
- SMR:   A9WA97
- GeneID:   5828534
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_1428
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- ProtClustDB:   PRK03932
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 50043; Mature: 49911

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLPTATVATIARYVGQRVTLAGWVYHKTEKGKLIFILLRDGSGTIQCVTFKKNVSEET
CCCCCHHHHHHHHHHHCCCEEEEEEEEEECCCCCEEEEEEECCCCEEEEEEECCCCCHHH
FATAQSLTQESSCRITGSVRADERAPGGYELDVESIELIGPSHEYPITPKEHGVEFLMAH
HHHHHHHCCCCCCEEEECCCCCCCCCCCEEEECCEEEEECCCCCCCCCCHHHHHHHHHHH
RHLWVRSAKQHAILRIRAEVIAAAQEWLNEQGFVRFDTPILTATAAEGTTNLFATDYFDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCCEEEECHHHH
GKAYLAQTGQLYVEAGMMAFGKVYCFGPTFRAEKSKTRRHLTEFWMIEPEVAFADHEDNM
HHHHHHCCCCEEEEHHHHHHCEEEEECCCCCCHHHHHHHHHHHHEEECCCEEECCCCCCC
RLQEEFVSAIVARVLERRRDDLQTLERDTTLLEQVRPPFPRITYDEAIELIAAHQGEVEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCC
ADPLPWGEDFGAPHETLIASKFDRPVFVERFPSAVKAFYMQPDPERPEVALCADLLAPEG
CCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCC
YGEIIGGSQRIHDPILLEQRIREHGLRIEDYEWYLDLRRYGTVPHSGFGMGIERVVAWIT
CCHHCCCCCCCCCHHHHHHHHHHCCCEEECHHHEEEHHHHCCCCCCCCCCCHHHHHHHHH
GTRHIRETIPFPRQLYRIYP
CCHHHHHHCCCCHHHHCCCC
>Mature Secondary Structure 
SLLPTATVATIARYVGQRVTLAGWVYHKTEKGKLIFILLRDGSGTIQCVTFKKNVSEET
CCCCHHHHHHHHHHHCCCEEEEEEEEEECCCCCEEEEEEECCCCEEEEEEECCCCCHHH
FATAQSLTQESSCRITGSVRADERAPGGYELDVESIELIGPSHEYPITPKEHGVEFLMAH
HHHHHHHCCCCCCEEEECCCCCCCCCCCEEEECCEEEEECCCCCCCCCCHHHHHHHHHHH
RHLWVRSAKQHAILRIRAEVIAAAQEWLNEQGFVRFDTPILTATAAEGTTNLFATDYFDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCCEEEECHHHH
GKAYLAQTGQLYVEAGMMAFGKVYCFGPTFRAEKSKTRRHLTEFWMIEPEVAFADHEDNM
HHHHHHCCCCEEEEHHHHHHCEEEEECCCCCCHHHHHHHHHHHHEEECCCEEECCCCCCC
RLQEEFVSAIVARVLERRRDDLQTLERDTTLLEQVRPPFPRITYDEAIELIAAHQGEVEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCC
ADPLPWGEDFGAPHETLIASKFDRPVFVERFPSAVKAFYMQPDPERPEVALCADLLAPEG
CCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCC
YGEIIGGSQRIHDPILLEQRIREHGLRIEDYEWYLDLRRYGTVPHSGFGMGIERVVAWIT
CCHHCCCCCCCCCHHHHHHHHHHCCCEEECHHHEEEHHHHCCCCCCCCCCCHHHHHHHHH
GTRHIRETIPFPRQLYRIYP
CCHHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA