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The map label for this gene is xpt

Identifier: 222524814

GI number: 222524814

Start: 1961592

End: 1962227

Strand: Reverse

Name: xpt

Synonym: Chy400_1541

Alternate gene names: 222524814

Gene position: 1962227-1961592 (Counterclockwise)

Preceding gene: 222524815

Following gene: 222524812

Centisome position: 37.24

GC content: 52.04

Gene sequence:

>636_bases
ATGCAACTGGTTGAACGCTTTTTGTGCGAACCCTTTCCTCCGCTTGCTCAACGTATCATCCAGGAGGGTGTTGTTGTTAA
TGATCGTATCCTCAAGATCGATCACTTCCTCAACCATCGGATTGATACAGACCTGATGTCTGCTATTGGTGTTGAACTGG
CAACTCGCTTACAACCATTTGCCGCTGAGTTAATTCTGACCGCAGAGGCAAGTGGTATTCCACCGGCGCTGGCCACAGCC
CTTGCTGCCCGGTTGCCTCTCGTGTATGCGAAAAAGTACGATCCCGATGTTCCAGTGCCGGCATTGACCCGCCATATCCA
TTCACCAACCCGTGATCGTCAGGTTCAACTGGCAATCTCAGCCCGCTTTATTCCTGCGGGGAGTCGTGTGGCGATTGTCG
ATGATTTTCTGGCTAATGGTCGTACTGCACTGGCTTTGGCCGATATGGTGTACGAGGCTGGAGCTACTGTGGTTGCCGCA
GCATTTGTGGTTGAAAAGCAGTTTCAAGAAGGGCGGTTGTTGCTGCAAAAGCTGGGAGTCCCTATCATCTCGCTGGCACA
GATTACGCGCTTTGTTGATGGCAGGCCTCTTATTTATGGCTGGCCATCATCTGTGCCGGGACAATCAGACGGGTAG

Upstream 100 bases:

>100_bases
CACACTTTCCACAAGCCTACGATCATGACGAATTTCTTCTTGCGCTTTATTATTTTGATGTTAAGGGAGTTACCTGTTTA
TAGTGGTGTGGATATATCCT

Downstream 100 bases:

>100_bases
GTTGTTCCTATCGGAAACCTGTAGTCCCGTGGGCGAATGACAGAGATATTGATTGGCTTACCCTGATACGGAAAAAGAGC
GCACGGTCAGTTTTGCTTCT

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MQLVERFLCEPFPPLAQRIIQEGVVVNDRILKIDHFLNHRIDTDLMSAIGVELATRLQPFAAELILTAEASGIPPALATA
LAARLPLVYAKKYDPDVPVPALTRHIHSPTRDRQVQLAISARFIPAGSRVAIVDDFLANGRTALALADMVYEAGATVVAA
AFVVEKQFQEGRLLLQKLGVPIISLAQITRFVDGRPLIYGWPSSVPGQSDG

Sequences:

>Translated_211_residues
MQLVERFLCEPFPPLAQRIIQEGVVVNDRILKIDHFLNHRIDTDLMSAIGVELATRLQPFAAELILTAEASGIPPALATA
LAARLPLVYAKKYDPDVPVPALTRHIHSPTRDRQVQLAISARFIPAGSRVAIVDDFLANGRTALALADMVYEAGATVVAA
AFVVEKQFQEGRLLLQKLGVPIISLAQITRFVDGRPLIYGWPSSVPGQSDG
>Mature_211_residues
MQLVERFLCEPFPPLAQRIIQEGVVVNDRILKIDHFLNHRIDTDLMSAIGVELATRLQPFAAELILTAEASGIPPALATA
LAARLPLVYAKKYDPDVPVPALTRHIHSPTRDRQVQLAISARFIPAGSRVAIVDDFLANGRTALALADMVYEAGATVVAA
AFVVEKQFQEGRLLLQKLGVPIISLAQITRFVDGRPLIYGWPSSVPGQSDG

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XPT_CHLAA (A9WA88)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001635036.1
- ProteinModelPortal:   A9WA88
- SMR:   A9WA88
- GeneID:   5828525
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_1419
- HOGENOM:   HBG288993
- OMA:   ATVYSFT
- ProtClustDB:   CLSK2488558
- GO:   GO:0005737
- HAMAP:   MF_01184
- InterPro:   IPR000836
- InterPro:   IPR010079
- TIGRFAMs:   TIGR01744

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 22951; Mature: 22951

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 31-31 BINDING 38-38 BINDING 166-166

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLVERFLCEPFPPLAQRIIQEGVVVNDRILKIDHFLNHRIDTDLMSAIGVELATRLQPF
CCHHHHHHCCCCCHHHHHHHHCCCEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AAELILTAEASGIPPALATALAARLPLVYAKKYDPDVPVPALTRHIHSPTRDRQVQLAIS
HHHHEEECCCCCCCHHHHHHHHHHCCHHEECCCCCCCCHHHHHHHHCCCCCCCEEEEEEE
ARFIPAGSRVAIVDDFLANGRTALALADMVYEAGATVVAAAFVVEKQFQEGRLLLQKLGV
EEEECCCCEEEEEHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
PIISLAQITRFVDGRPLIYGWPSSVPGQSDG
CHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MQLVERFLCEPFPPLAQRIIQEGVVVNDRILKIDHFLNHRIDTDLMSAIGVELATRLQPF
CCHHHHHHCCCCCHHHHHHHHCCCEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AAELILTAEASGIPPALATALAARLPLVYAKKYDPDVPVPALTRHIHSPTRDRQVQLAIS
HHHHEEECCCCCCCHHHHHHHHHHCCHHEECCCCCCCCHHHHHHHHCCCCCCCEEEEEEE
ARFIPAGSRVAIVDDFLANGRTALALADMVYEAGATVVAAAFVVEKQFQEGRLLLQKLGV
EEEECCCCEEEEEHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
PIISLAQITRFVDGRPLIYGWPSSVPGQSDG
CHHHHHHHHHHHCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA