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The map label for this gene is trpS [H]

Identifier: 222524803

GI number: 222524803

Start: 1949692

End: 1950702

Strand: Reverse

Name: trpS [H]

Synonym: Chy400_1530

Alternate gene names: 222524803

Gene position: 1950702-1949692 (Counterclockwise)

Preceding gene: 222524805

Following gene: 222524802

Centisome position: 37.02

GC content: 56.08

Gene sequence:

>1011_bases
ATGACGCGCAAACCTCGTGTCTTCTCAGGCATCCAGCCGTCGGGCAACCTGCATATCGGTAACTATCTGGGTGCGATCCA
GCAATGGGTTGCCGGGCAGGGCCAGAAGACCAATTTCATCTGTATCGTCGATCTGCATGCGATCACCGTACCGCAAGACC
CAGCCGACTTGCGTCGCCAGACCCGCGAGTTAGCCGCCTTGTTGCTGGCTTGTGGTATCGATCCGCAGCAGACGACGCTC
TTCGTGCAGAGTCACGTGCGGGCGCATGCCGAGTGTTCGTGGGTGTTCAGTTGTATCACACCGCTTGGCTGGCTCGAACG
CATGACCCAGTACAAGACGAAAGCGCAGAAGCAAGAGAGCGTGATGACCGGTTTGCTCACCTATCCGGTCTTGATGGCGG
CAGACATTCTGCTCTACGATGCCGACGAGGTGCCGGTTGGCGAGGACCAAAAGCAGCATATCGAGCTGACCCGCGATCTC
GCGCAGCGCTTCAATTATCTCTTTGGGGAAACCTTTGTTATTCCCAAACCAGTCATTCGCGAGAGCGGCGCTCGCATTAT
GGGCCTCAACGATCCGACAGTCAAGATGAGCAAATCGGAAACAACCCGTGGTCATGCGATTCGCATTGTTGACGATCCCG
ACGAGATTCGCTGGGCGATCAAGCGGGCAGTTACCGACTCCTACAACGAGATTCGCTTTAGCGATGACCCTGATCGTGCC
GGGGTGAATAATCTGTTGCAAATCTATGAATTGCTGACCGGGCGTAGCCGACCAGAGATCGAAGCACACTTTGCCGGTAA
GGGGTATGGTGCGCTGAAGCGAGAACTCACCGAGGTAGTGATTGAGTCGTTGCGCCCGATCCGCGAGCGCTACTACCAGT
TGATGAACGATCCGGCGGAGCTTGATCGTATACTGGCGATTGGCGCCGAACAGGCACGTGCCGTGGCTGAACCGAAGATG
ACGCTTATCCTTGAGCGGGTAGGCTTCGTATTACCCAATGACCGTAGATAA

Upstream 100 bases:

>100_bases
AGGAAGAGAAATCGTTTCATTGCATACCTGATATGAAAGCGATACCTGACATTGCTTAGTATAGCATGTTTCGCATTGTA
GCCTTAAGGAGAGAAACCCT

Downstream 100 bases:

>100_bases
GGAATTGTATGTACTATCCAACCCTCGATCAATTACAGGAGTTACGCCAGCAGGGTAATCTCTGCCCCATTTATCGCGAG
ATTATGGCTGATCTGGAGAC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTRKPRVFSGIQPSGNLHIGNYLGAIQQWVAGQGQKTNFICIVDLHAITVPQDPADLRRQTRELAALLLACGIDPQQTTL
FVQSHVRAHAECSWVFSCITPLGWLERMTQYKTKAQKQESVMTGLLTYPVLMAADILLYDADEVPVGEDQKQHIELTRDL
AQRFNYLFGETFVIPKPVIRESGARIMGLNDPTVKMSKSETTRGHAIRIVDDPDEIRWAIKRAVTDSYNEIRFSDDPDRA
GVNNLLQIYELLTGRSRPEIEAHFAGKGYGALKRELTEVVIESLRPIRERYYQLMNDPAELDRILAIGAEQARAVAEPKM
TLILERVGFVLPNDRR

Sequences:

>Translated_336_residues
MTRKPRVFSGIQPSGNLHIGNYLGAIQQWVAGQGQKTNFICIVDLHAITVPQDPADLRRQTRELAALLLACGIDPQQTTL
FVQSHVRAHAECSWVFSCITPLGWLERMTQYKTKAQKQESVMTGLLTYPVLMAADILLYDADEVPVGEDQKQHIELTRDL
AQRFNYLFGETFVIPKPVIRESGARIMGLNDPTVKMSKSETTRGHAIRIVDDPDEIRWAIKRAVTDSYNEIRFSDDPDRA
GVNNLLQIYELLTGRSRPEIEAHFAGKGYGALKRELTEVVIESLRPIRERYYQLMNDPAELDRILAIGAEQARAVAEPKM
TLILERVGFVLPNDRR
>Mature_335_residues
TRKPRVFSGIQPSGNLHIGNYLGAIQQWVAGQGQKTNFICIVDLHAITVPQDPADLRRQTRELAALLLACGIDPQQTTLF
VQSHVRAHAECSWVFSCITPLGWLERMTQYKTKAQKQESVMTGLLTYPVLMAADILLYDADEVPVGEDQKQHIELTRDLA
QRFNYLFGETFVIPKPVIRESGARIMGLNDPTVKMSKSETTRGHAIRIVDDPDEIRWAIKRAVTDSYNEIRFSDDPDRAG
VNNLLQIYELLTGRSRPEIEAHFAGKGYGALKRELTEVVIESLRPIRERYYQLMNDPAELDRILAIGAEQARAVAEPKMT
LILERVGFVLPNDRR

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=329, Percent_Identity=44.9848024316109, Blast_Score=280, Evalue=1e-75,
Organism=Homo sapiens, GI41352700, Length=178, Percent_Identity=55.6179775280899, Blast_Score=200, Evalue=2e-51,
Organism=Escherichia coli, GI1789786, Length=330, Percent_Identity=52.4242424242424, Blast_Score=336, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI71982800, Length=331, Percent_Identity=38.9728096676737, Blast_Score=214, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI71982793, Length=331, Percent_Identity=38.9728096676737, Blast_Score=212, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6320474, Length=351, Percent_Identity=38.1766381766382, Blast_Score=221, Evalue=9e-59,
Organism=Drosophila melanogaster, GI24666151, Length=331, Percent_Identity=44.4108761329305, Blast_Score=273, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 38010; Mature: 37879

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKPRVFSGIQPSGNLHIGNYLGAIQQWVAGQGQKTNFICIVDLHAITVPQDPADLRRQ
CCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCCHHHHHHH
TRELAALLLACGIDPQQTTLFVQSHVRAHAECSWVFSCITPLGWLERMTQYKTKAQKQES
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMTGLLTYPVLMAADILLYDADEVPVGEDQKQHIELTRDLAQRFNYLFGETFVIPKPVIR
HHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCHHHH
ESGARIMGLNDPTVKMSKSETTRGHAIRIVDDPDEIRWAIKRAVTDSYNEIRFSDDPDRA
CCCCEEEECCCCCEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GVNNLLQIYELLTGRSRPEIEAHFAGKGYGALKRELTEVVIESLRPIRERYYQLMNDPAE
CHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LDRILAIGAEQARAVAEPKMTLILERVGFVLPNDRR
HHHHHHHCHHHHHHHHCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TRKPRVFSGIQPSGNLHIGNYLGAIQQWVAGQGQKTNFICIVDLHAITVPQDPADLRRQ
CCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCCHHHHHHH
TRELAALLLACGIDPQQTTLFVQSHVRAHAECSWVFSCITPLGWLERMTQYKTKAQKQES
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMTGLLTYPVLMAADILLYDADEVPVGEDQKQHIELTRDLAQRFNYLFGETFVIPKPVIR
HHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCHHHH
ESGARIMGLNDPTVKMSKSETTRGHAIRIVDDPDEIRWAIKRAVTDSYNEIRFSDDPDRA
CCCCEEEECCCCCEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GVNNLLQIYELLTGRSRPEIEAHFAGKGYGALKRELTEVVIESLRPIRERYYQLMNDPAE
CHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LDRILAIGAEQARAVAEPKMTLILERVGFVLPNDRR
HHHHHHHCHHHHHHHHCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500908 [H]