Click here to switch to the map view.

The map label for this gene is crp [C]

Identifier: 222524672

GI number: 222524672

Start: 1780597

End: 1781277

Strand: Reverse

Name: crp [C]

Synonym: Chy400_1399

Alternate gene names: 222524672

Gene position: 1781277-1780597 (Counterclockwise)

Preceding gene: 222524673

Following gene: 222524671

Centisome position: 33.81

GC content: 54.92

Gene sequence:

>681_bases
ATGTTGCAACCGCACGAAATGCATCTGGCGGGTGATCTATTAGACTTCTTGCGCGATCCATCTACTGCCATTGCCCGCGA
TTTTGCTACGCAGGCGACACTCATGCGTATCGCAAGCGGTGCAACCGTTTTTGCCGAAGGCGATGAGTGTAGCTTTTTTG
CGATTCTTGCCGATGGTCAGATTCGGGTGTTCAAAATTGGCGAAACCGGACGGGAGATTACGCTCTATCGGTTTGGTCGT
GGTGAGAGCTGCATTCTCACTACCAGTTGTGTCTTGAGTAACCATCAGTTCCCGGCAATCGCTGTGGTTGAACGTGAGGC
AACCGCCTTTCTGGTTGGTCAGGCAATCTTTCGCGATTGGATCGAGCGCTATAGCGCCTGGCGTGACTATGTCTTTCAAC
TGCTTTCAAGGCGGCTGGCATCGGTAATGGCAATCATTGACGAGATCGCCTTCCGACGGGTTGATGTGCGCCTGGCGGCA
TTTCTGCTGCGGCAGGCTGTTGGTGATCCGCCTACACTCAATCTCACCCATCAGCAAATTGCCGCCGAGCTAGGCACATC
GCGCGAAGTCGTCAGTCGCATTCTGGCCGACTTCAGTGAGGAGGGGCTTATCAGCAGCAGTCGCGGGCAAATCACGGTGT
GTGATCGAACGCGCCTGTATCAGCGGAGCGAAGCGCGCTGA

Upstream 100 bases:

>100_bases
GCCAGTTTGCGGGTCGATGAGCGGGTGATCGTTGATCAGGGACGTTTGATCGTGTAACTGTTCGTCCTACACGTCGTTAG
ACAGGAGCATTAGAGCGATA

Downstream 100 bases:

>100_bases
AGCCGACCGGAAAGGAGACTGCGGTGGATGTGTCGGTGCTGACGCAGAAACTCAGTGATAATGCCAGACGGATACAGGTA
TTGCTTGCAGGGGCATCGCT

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; Crp Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Transcriptional Regulator; CRP Family Transcriptional Regulator; Transcriptional Regulator Crp Family Protein; Crp-Fnr Regulatory Protein; Transcriptional Regulator Anr; Nitrite And Nitric Oxide Reductase Regulator; Transcription Regulator Nnr-Type; DNR Protein; Transcriptional Regulator Nnr-Like; CAMP-Bindin Transcriptional Regulator; Transcriptional Regulator Crp Family; Transcriptional Regulator Crp-Fnr Family; CRP Family Global Nitrogen Regulatory Protein; Transcriptional Regulator Crp/Fnr Family Protein

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MLQPHEMHLAGDLLDFLRDPSTAIARDFATQATLMRIASGATVFAEGDECSFFAILADGQIRVFKIGETGREITLYRFGR
GESCILTTSCVLSNHQFPAIAVVEREATAFLVGQAIFRDWIERYSAWRDYVFQLLSRRLASVMAIIDEIAFRRVDVRLAA
FLLRQAVGDPPTLNLTHQQIAAELGTSREVVSRILADFSEEGLISSSRGQITVCDRTRLYQRSEAR

Sequences:

>Translated_226_residues
MLQPHEMHLAGDLLDFLRDPSTAIARDFATQATLMRIASGATVFAEGDECSFFAILADGQIRVFKIGETGREITLYRFGR
GESCILTTSCVLSNHQFPAIAVVEREATAFLVGQAIFRDWIERYSAWRDYVFQLLSRRLASVMAIIDEIAFRRVDVRLAA
FLLRQAVGDPPTLNLTHQQIAAELGTSREVVSRILADFSEEGLISSSRGQITVCDRTRLYQRSEAR
>Mature_226_residues
MLQPHEMHLAGDLLDFLRDPSTAIARDFATQATLMRIASGATVFAEGDECSFFAILADGQIRVFKIGETGREITLYRFGR
GESCILTTSCVLSNHQFPAIAVVEREATAFLVGQAIFRDWIERYSAWRDYVFQLLSRRLASVMAIIDEIAFRRVDVRLAA
FLLRQAVGDPPTLNLTHQQIAAELGTSREVVSRILADFSEEGLISSSRGQITVCDRTRLYQRSEAR

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25335; Mature: 25335

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQPHEMHLAGDLLDFLRDPSTAIARDFATQATLMRIASGATVFAEGDECSFFAILADGQ
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCE
IRVFKIGETGREITLYRFGRGESCILTTSCVLSNHQFPAIAVVEREATAFLVGQAIFRDW
EEEEEECCCCCEEEEEEECCCCEEEEEHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHH
IERYSAWRDYVFQLLSRRLASVMAIIDEIAFRRVDVRLAAFLLRQAVGDPPTLNLTHQQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AAELGTSREVVSRILADFSEEGLISSSRGQITVCDRTRLYQRSEAR
HHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHCCCC
>Mature Secondary Structure
MLQPHEMHLAGDLLDFLRDPSTAIARDFATQATLMRIASGATVFAEGDECSFFAILADGQ
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCE
IRVFKIGETGREITLYRFGRGESCILTTSCVLSNHQFPAIAVVEREATAFLVGQAIFRDW
EEEEEECCCCCEEEEEEECCCCEEEEEHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHH
IERYSAWRDYVFQLLSRRLASVMAIIDEIAFRRVDVRLAAFLLRQAVGDPPTLNLTHQQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AAELGTSREVVSRILADFSEEGLISSSRGQITVCDRTRLYQRSEAR
HHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA