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The map label for this gene is crp [H]

Identifier: 222524613

GI number: 222524613

Start: 1709386

End: 1710036

Strand: Reverse

Name: crp [H]

Synonym: Chy400_1337

Alternate gene names: 222524613

Gene position: 1710036-1709386 (Counterclockwise)

Preceding gene: 222524614

Following gene: 222524611

Centisome position: 32.45

GC content: 60.52

Gene sequence:

>651_bases
ATGACGATTGAAGACCTGCGCGCTATTCCGTTATTTGCCACGCTCGATGAGGCAACTCTGGCCGATACTGCCCGTCGTGT
GCAGATATGTCATTATCGCCCCGGTCAGCATATCATCTATGAAGACCAGCCGGCACACGCGATCTTCTTTGTGGTGCGCG
GTCGGGTCAGACTGTCACGCACGGCACCTGATGGTCGCGAGCAGGTGCTGGCAATGGTTGGGCCGGGAGAATATTTTAAC
GCTGTGCCGATCTTCGACGCCGGGCTAAGTCCGGCCACTGCTCGTGCGATGAGTCAGGTCACCTGTTTACTGCTGGCACG
CGAGGATTTGCTGGCGCTCATTCGGAAACACCCCGATCTGGCGCTGGCAGCGCTCTCTGATCTGGCCGGACAGTTACGTG
AGCTGGTTACTCTGGTTGAGGATTTGGCCTTTCGTTCGGTACGTGCCCGTCTGGCGCGCCTGTTGCTGGCCGAGGCAGCC
GAAGGCACCGCCGAAGTCACGCAGCAGGAATTGGCCGAACGTACCGGTACCGTGCGCGAGATTGCCGGACGGGCCCTACG
GCGGATGGCCGAAGAACGCCTGGTCAAGTTAGAGCGTGGCCGGGTGGTTGTGCTGGATCGAGTGCGGCTGGCGAAGGTGG
CCGAAGAGTAG

Upstream 100 bases:

>100_bases
CCCCACCGTAACTTACTCACGTACAAAACTCTCTATAATGAATAGCAACAGCGGCACTGTGCCTGCTGTGCAGTATGTGA
TACACATTGTGGGCAGCGCA

Downstream 100 bases:

>100_bases
GGAGAAGCTATCTCGGAGCAGTGAAGTGATGTGACAGGCATCACACCTCTCGCGAGTTTCGCGAGCGTTTGTACGATGAT
GGCATTCGTTCACGCTCCTA

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: cAMP receptor protein; cAMP regulatory protein [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MTIEDLRAIPLFATLDEATLADTARRVQICHYRPGQHIIYEDQPAHAIFFVVRGRVRLSRTAPDGREQVLAMVGPGEYFN
AVPIFDAGLSPATARAMSQVTCLLLAREDLLALIRKHPDLALAALSDLAGQLRELVTLVEDLAFRSVRARLARLLLAEAA
EGTAEVTQQELAERTGTVREIAGRALRRMAEERLVKLERGRVVVLDRVRLAKVAEE

Sequences:

>Translated_216_residues
MTIEDLRAIPLFATLDEATLADTARRVQICHYRPGQHIIYEDQPAHAIFFVVRGRVRLSRTAPDGREQVLAMVGPGEYFN
AVPIFDAGLSPATARAMSQVTCLLLAREDLLALIRKHPDLALAALSDLAGQLRELVTLVEDLAFRSVRARLARLLLAEAA
EGTAEVTQQELAERTGTVREIAGRALRRMAEERLVKLERGRVVVLDRVRLAKVAEE
>Mature_215_residues
TIEDLRAIPLFATLDEATLADTARRVQICHYRPGQHIIYEDQPAHAIFFVVRGRVRLSRTAPDGREQVLAMVGPGEYFNA
VPIFDAGLSPATARAMSQVTCLLLAREDLLALIRKHPDLALAALSDLAGQLRELVTLVEDLAFRSVRARLARLLLAEAAE
GTAEVTQQELAERTGTVREIAGRALRRMAEERLVKLERGRVVVLDRVRLAKVAEE

Specific function: This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of one or more genes involved in the induction of competence [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789756, Length=188, Percent_Identity=24.468085106383, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR018488
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 23939; Mature: 23808

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIEDLRAIPLFATLDEATLADTARRVQICHYRPGQHIIYEDQPAHAIFFVVRGRVRLSR
CCHHHHHHCCHHHCCCHHHHHHHHHHHEEEEECCCCEEEECCCCCCEEEEEEECCEEEEC
TAPDGREQVLAMVGPGEYFNAVPIFDAGLSPATARAMSQVTCLLLAREDLLALIRKHPDL
CCCCHHHHEEEEECCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ALAALSDLAGQLRELVTLVEDLAFRSVRARLARLLLAEAAEGTAEVTQQELAERTGTVRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHH
IAGRALRRMAEERLVKLERGRVVVLDRVRLAKVAEE
HHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCC
>Mature Secondary Structure 
TIEDLRAIPLFATLDEATLADTARRVQICHYRPGQHIIYEDQPAHAIFFVVRGRVRLSR
CHHHHHHCCHHHCCCHHHHHHHHHHHEEEEECCCCEEEECCCCCCEEEEEEECCEEEEC
TAPDGREQVLAMVGPGEYFNAVPIFDAGLSPATARAMSQVTCLLLAREDLLALIRKHPDL
CCCCHHHHEEEEECCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ALAALSDLAGQLRELVTLVEDLAFRSVRARLARLLLAEAAEGTAEVTQQELAERTGTVRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHH
IAGRALRRMAEERLVKLERGRVVVLDRVRLAKVAEE
HHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1542653; 7542800 [H]