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The map label for this gene is degU [H]

Identifier: 222524601

GI number: 222524601

Start: 1696899

End: 1697534

Strand: Reverse

Name: degU [H]

Synonym: Chy400_1325

Alternate gene names: 222524601

Gene position: 1697534-1696899 (Counterclockwise)

Preceding gene: 222524605

Following gene: 222524600

Centisome position: 32.22

GC content: 56.29

Gene sequence:

>636_bases
GTGATCCGGGTCTTCATTGTTGATGACCACCCGATTGTGCGTGAAGGTTTGCGGAGTCTGATCCAGCATCAGCCTGATAT
GACGCTGGTCGGGGAAGCCGATGACGGTACCAAAGTGATTTCGTCCATCACCACCTTGAAGCCTGATGTGGTGGTGATCG
ATCTCCGGATGCCGGGTCTTGATGGGCTGGGGGTGTTACGACAGGCTCAGGCGCTTACACCTGCACCATCGTGTCTGGTG
CTTTCCAGCTACAACGAACCTGACTATGTGATTGCGGCAATCGAAGCCGGGGCACGTGGCTTTCTCCTCAAGCAGAGTGC
CTACACGGCCATTCTTGATGCGATTCGGGCCATCGCTAACGGCGAATATGTCATCTCGCCGAATCTGGTGGGTGTACTGT
TTACAAACGTGGCTGAACTTCAGCGCGAGCGGTTGCGTCAGGCGTTGGCCGATGATGAGAGTGCGTTGCGCCTGCTGAAA
GCCCTGGCGGATGGCGCTACCACCTTAGAGATTGGGGCTATGCTGCATATGAGTGAGGTGACGGTCAAGCGCCGGATTCA
GGATCTGATCAAACTCCTCGGTGTGCGTAATCGGACGCAACTGGTGGCAGAGGCAGTGCGGCGTGGTTGGATTTAG

Upstream 100 bases:

>100_bases
TCCTGATTACTATGACAAAATCGGGATGCTCAACGATAGGCAACGAAGCCTTGTCAGGTCGAACTGATATTCACAGGTCA
CGATGTGAGAGGAGTTGGCC

Downstream 100 bases:

>100_bases
AGGATGTTAGATCAATCCGGTTTACTGGAAGTTATCTCATTCATTCCTGACAAACGCCGTGATCGTGACGAGTACACACC
GAATTCCTGTGACCAGCATG

Product: LuxR family two component transcriptional regulator

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MIRVFIVDDHPIVREGLRSLIQHQPDMTLVGEADDGTKVISSITTLKPDVVVIDLRMPGLDGLGVLRQAQALTPAPSCLV
LSSYNEPDYVIAAIEAGARGFLLKQSAYTAILDAIRAIANGEYVISPNLVGVLFTNVAELQRERLRQALADDESALRLLK
ALADGATTLEIGAMLHMSEVTVKRRIQDLIKLLGVRNRTQLVAEAVRRGWI

Sequences:

>Translated_211_residues
MIRVFIVDDHPIVREGLRSLIQHQPDMTLVGEADDGTKVISSITTLKPDVVVIDLRMPGLDGLGVLRQAQALTPAPSCLV
LSSYNEPDYVIAAIEAGARGFLLKQSAYTAILDAIRAIANGEYVISPNLVGVLFTNVAELQRERLRQALADDESALRLLK
ALADGATTLEIGAMLHMSEVTVKRRIQDLIKLLGVRNRTQLVAEAVRRGWI
>Mature_211_residues
MIRVFIVDDHPIVREGLRSLIQHQPDMTLVGEADDGTKVISSITTLKPDVVVIDLRMPGLDGLGVLRQAQALTPAPSCLV
LSSYNEPDYVIAAIEAGARGFLLKQSAYTAILDAIRAIANGEYVISPNLVGVLFTNVAELQRERLRQALADDESALRLLK
ALADGATTLEIGAMLHMSEVTVKRRIQDLIKLLGVRNRTQLVAEAVRRGWI

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=203, Percent_Identity=35.9605911330049, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1790102, Length=210, Percent_Identity=30.952380952381, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788222, Length=210, Percent_Identity=27.6190476190476, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1787473, Length=184, Percent_Identity=34.2391304347826, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1786747, Length=202, Percent_Identity=27.2277227722772, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1788712, Length=207, Percent_Identity=27.536231884058, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788546, Length=204, Percent_Identity=28.921568627451, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082052, Length=106, Percent_Identity=38.6792452830189, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23030; Mature: 23030

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVFIVDDHPIVREGLRSLIQHQPDMTLVGEADDGTKVISSITTLKPDVVVIDLRMPGL
CEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCC
DGLGVLRQAQALTPAPSCLVLSSYNEPDYVIAAIEAGARGFLLKQSAYTAILDAIRAIAN
CCHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHC
GEYVISPNLVGVLFTNVAELQRERLRQALADDESALRLLKALADGATTLEIGAMLHMSEV
CCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHH
TVKRRIQDLIKLLGVRNRTQLVAEAVRRGWI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MIRVFIVDDHPIVREGLRSLIQHQPDMTLVGEADDGTKVISSITTLKPDVVVIDLRMPGL
CEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCC
DGLGVLRQAQALTPAPSCLVLSSYNEPDYVIAAIEAGARGFLLKQSAYTAILDAIRAIAN
CCHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHC
GEYVISPNLVGVLFTNVAELQRERLRQALADDESALRLLKALADGATTLEIGAMLHMSEV
CCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHH
TVKRRIQDLIKLLGVRNRTQLVAEAVRRGWI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]