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The map label for this gene is lysK [H]

Identifier: 222524593

GI number: 222524593

Start: 1683632

End: 1684681

Strand: Reverse

Name: lysK [H]

Synonym: Chy400_1317

Alternate gene names: 222524593

Gene position: 1684681-1683632 (Counterclockwise)

Preceding gene: 222524597

Following gene: 222524592

Centisome position: 31.97

GC content: 60.67

Gene sequence:

>1050_bases
ATGAAGCATGATGCTGTTGAATTTCTTGTTCGTTTGCTGCGCACGCCATCGCTTTCCGGTCAGGAAGCGGCGGCAGTTGC
GGTGATGGTTGACCAGATGCGCTCCTTCGGTTGGGAAGCCTTTGTTGACGAAGCGGGGAGTGCGGTTGGGCTGATCGGTA
GCGAAGGGCCGCTGGTTGTGCTGCTTGGTCATATCGATACGGTACCCGGCGAGGTGCCGGTACGGATCGAGGACGGCAGG
CTCTACGGACGTGGGGCGGTTGATGCCAAGGGGCCACTGGCAACGTTTGTCTGGGCCGCCCGCCAGGCCGAGCTGTCGGG
AACGTTGGGGTGTCGGCTGGTGATTATTGGGGCTACCGAAGAAGAGGCCGCAAGTTCACGCGGTGCCCATGCGGCTCGTG
ACCGCTACCGCCCCGATTTTTGTGTGATCGGTGAACCGAGTGGTTGGGATCGGATTACGCTCGGCTACAAAGGTCGACTC
CTGGTCAATTATCATTACCGGCAACCGGTTGCGCACAGTGCCGGTGAGCAGCGCGCAGCGCCAGAGGTGATGGTTGATTT
CTGGCGTGCCGTTGAACAGTACTGCCAGAGTATCAATGCCGGTCGTACCCGACTGTTCGAGCAGTTGATCCCTTCGTTGC
GGCGTGTGCATAGCGATAGCGATGGCATTACCGAATGGGTGGAAGCAACGATTGGTTTGCGGCTACCCCCCGGTATCGAT
CCCGCGGCGTTGGCCGATACCCTGCACATGCTGGCCGGTACTGCTGAAGTCTCCTTCACCGGCGCCTGCCCCGCCTTTCA
GAGTCCACGCACAACACCGCTGGCGAGCGCGTTTGTGCGTGCGATCCGGCAACACGGCGGCCAACCGGCATTCCTCCACA
AGACCGGCACTGCCGATATGAATGTGGTTGGGCCGGTGTGGCAGTGTCCGATTGTCGCTTACGGGCCGGGCGACTCACGG
CTTGATCATACGCCCAATGAGCATCTTGAACTGGCCGAGTACGAGCGGGCAATTGCTGTGCTGGCCGGGGTACTCGCTCA
GTTGCGTTGA

Upstream 100 bases:

>100_bases
CTTATTTATCACATACCCTGCTCTTTATCTATTACATTGTTATTTAATTCTAAAGGTTCGATACCTGACGACATAATGTT
CCTGATCAGGAGTCTGCCTT

Downstream 100 bases:

>100_bases
CGATCAGCCCGGTCTGTGCTACCATCGGCTACGATTGAATTGAATACAAGCAACACGGGACTGGCAATTGCTAGACGTTA
TATACCTTAACGTGTTATGG

Product: acetyl-lysine deacetylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MKHDAVEFLVRLLRTPSLSGQEAAAVAVMVDQMRSFGWEAFVDEAGSAVGLIGSEGPLVVLLGHIDTVPGEVPVRIEDGR
LYGRGAVDAKGPLATFVWAARQAELSGTLGCRLVIIGATEEEAASSRGAHAARDRYRPDFCVIGEPSGWDRITLGYKGRL
LVNYHYRQPVAHSAGEQRAAPEVMVDFWRAVEQYCQSINAGRTRLFEQLIPSLRRVHSDSDGITEWVEATIGLRLPPGID
PAALADTLHMLAGTAEVSFTGACPAFQSPRTTPLASAFVRAIRQHGGQPAFLHKTGTADMNVVGPVWQCPIVAYGPGDSR
LDHTPNEHLELAEYERAIAVLAGVLAQLR

Sequences:

>Translated_349_residues
MKHDAVEFLVRLLRTPSLSGQEAAAVAVMVDQMRSFGWEAFVDEAGSAVGLIGSEGPLVVLLGHIDTVPGEVPVRIEDGR
LYGRGAVDAKGPLATFVWAARQAELSGTLGCRLVIIGATEEEAASSRGAHAARDRYRPDFCVIGEPSGWDRITLGYKGRL
LVNYHYRQPVAHSAGEQRAAPEVMVDFWRAVEQYCQSINAGRTRLFEQLIPSLRRVHSDSDGITEWVEATIGLRLPPGID
PAALADTLHMLAGTAEVSFTGACPAFQSPRTTPLASAFVRAIRQHGGQPAFLHKTGTADMNVVGPVWQCPIVAYGPGDSR
LDHTPNEHLELAEYERAIAVLAGVLAQLR
>Mature_349_residues
MKHDAVEFLVRLLRTPSLSGQEAAAVAVMVDQMRSFGWEAFVDEAGSAVGLIGSEGPLVVLLGHIDTVPGEVPVRIEDGR
LYGRGAVDAKGPLATFVWAARQAELSGTLGCRLVIIGATEEEAASSRGAHAARDRYRPDFCVIGEPSGWDRITLGYKGRL
LVNYHYRQPVAHSAGEQRAAPEVMVDFWRAVEQYCQSINAGRTRLFEQLIPSLRRVHSDSDGITEWVEATIGLRLPPGID
PAALADTLHMLAGTAEVSFTGACPAFQSPRTTPLASAFVRAIRQHGGQPAFLHKTGTADMNVVGPVWQCPIVAYGPGDSR
LDHTPNEHLELAEYERAIAVLAGVLAQLR

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fifth step. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. LysK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788816, Length=389, Percent_Identity=25.4498714652956, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010175
- InterPro:   IPR002933 [H]

Pfam domain/function: PF01546 Peptidase_M20 [H]

EC number: 3.5.1.-

Molecular weight: Translated: 37661; Mature: 37661

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHDAVEFLVRLLRTPSLSGQEAAAVAVMVDQMRSFGWEAFVDEAGSAVGLIGSEGPLVV
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEECCCCCEEE
LLGHIDTVPGEVPVRIEDGRLYGRGAVDAKGPLATFVWAARQAELSGTLGCRLVIIGATE
EEECCCCCCCCEEEEEECCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCH
EEAASSRGAHAARDRYRPDFCVIGEPSGWDRITLGYKGRLLVNYHYRQPVAHSAGEQRAA
HHHHHCCCCHHHHHCCCCCEEEECCCCCCCEEEECCCCEEEEEEECCCCHHHCCCCHHCC
PEVMVDFWRAVEQYCQSINAGRTRLFEQLIPSLRRVHSDSDGITEWVEATIGLRLPPGID
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC
PAALADTLHMLAGTAEVSFTGACPAFQSPRTTPLASAFVRAIRQHGGQPAFLHKTGTADM
HHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCC
NVVGPVWQCPIVAYGPGDSRLDHTPNEHLELAEYERAIAVLAGVLAQLR
EECCCHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKHDAVEFLVRLLRTPSLSGQEAAAVAVMVDQMRSFGWEAFVDEAGSAVGLIGSEGPLVV
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEECCCCCEEE
LLGHIDTVPGEVPVRIEDGRLYGRGAVDAKGPLATFVWAARQAELSGTLGCRLVIIGATE
EEECCCCCCCCEEEEEECCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCH
EEAASSRGAHAARDRYRPDFCVIGEPSGWDRITLGYKGRLLVNYHYRQPVAHSAGEQRAA
HHHHHCCCCHHHHHCCCCCEEEECCCCCCCEEEECCCCEEEEEEECCCCHHHCCCCHHCC
PEVMVDFWRAVEQYCQSINAGRTRLFEQLIPSLRRVHSDSDGITEWVEATIGLRLPPGID
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC
PAALADTLHMLAGTAEVSFTGACPAFQSPRTTPLASAFVRAIRQHGGQPAFLHKTGTADM
HHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCC
NVVGPVWQCPIVAYGPGDSRLDHTPNEHLELAEYERAIAVLAGVLAQLR
EECCCHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA