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The map label for this gene is arnC [H]

Identifier: 222524533

GI number: 222524533

Start: 1601399

End: 1602157

Strand: Direct

Name: arnC [H]

Synonym: Chy400_1257

Alternate gene names: 222524533

Gene position: 1601399-1602157 (Clockwise)

Preceding gene: 222524526

Following gene: 222524535

Centisome position: 30.39

GC content: 52.04

Gene sequence:

>759_bases
ATGGACAAGCGACCCAGTATCAGCGTCTTTTTTCCCGCCTGCAATGATGCCGGTACAATTGGTAGTATGGTGGTTGCAGC
TATCGAGACGCTGGAAGAAATTACCGATGATTACGAGGTGATTGTTGTCGAGAATGGAAGTACTGACTACACGGTTGATG
TTCTCGAATCACTGGCAAAGCGCTATGATCGGCTGCGCGTGTACACACATCGCCAGGCGTTAGGGTACGGTGGAGCGTTA
CGGGTTGGCTTTGCCAAAGCAACGAAAGACCTGATCTTCTACACCGACGGCGATGCGCAGTACGATCCACGCGAACTCAA
GCTTCTCTTACCGGCACTGCGTGACGATATCGACATTGTGAATGGCTGGAAGATAGATCGCGGAGACCCGTTGCATCGCA
TTATCATCGGTCGTATCTACCACCACACGGTGAAATTTCTCTTCGGCTTTAAATTGCGCGACGTTGACTGCGATTTTCGG
CTTATTCGCCGGCATGTATTCGACGATATTGAGCTGGAATCAGACAGCGGGACGATTTGCCTGGAGCTGGTGAAGAAGCT
ACAAGATGCCGGCTATCGCTTCGCCGAAGTACCGGTTCATCACTACCACCGCACTTACGGCAAGAGTCAGTTCTTCAACT
TCCCACGGCTCTGGCGCACCTTTGTTCAACTTATTGGCCTGTGGTGGAAGCTGGTGGTACGTCGTGAGCACATGCGCAAG
CGCAAAAAGCGCCTGGCACCTGAAGAGATTGCTCGCTAA

Upstream 100 bases:

>100_bases
ACCGTAGCACAGCTTTACGTTCAGCCCCTGACGAGGAGTGCACGACGCCTGTGTTATAATCAGCCGGCGGCACTTCAAAC
GGCGCATGGAGTTCAACTGT

Downstream 100 bases:

>100_bases
CTCTGAGCCAGCTCGCGTAGTCGGGATGGGTTCAACAGGGTAATGCCGGAACTATCCACGTCGAGCAGACGGGCATCGCG
GAACTGATTAATGACCTTAG

Product: glycosyl transferase family 2 protein

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MDKRPSISVFFPACNDAGTIGSMVVAAIETLEEITDDYEVIVVENGSTDYTVDVLESLAKRYDRLRVYTHRQALGYGGAL
RVGFAKATKDLIFYTDGDAQYDPRELKLLLPALRDDIDIVNGWKIDRGDPLHRIIIGRIYHHTVKFLFGFKLRDVDCDFR
LIRRHVFDDIELESDSGTICLELVKKLQDAGYRFAEVPVHHYHRTYGKSQFFNFPRLWRTFVQLIGLWWKLVVRREHMRK
RKKRLAPEEIAR

Sequences:

>Translated_252_residues
MDKRPSISVFFPACNDAGTIGSMVVAAIETLEEITDDYEVIVVENGSTDYTVDVLESLAKRYDRLRVYTHRQALGYGGAL
RVGFAKATKDLIFYTDGDAQYDPRELKLLLPALRDDIDIVNGWKIDRGDPLHRIIIGRIYHHTVKFLFGFKLRDVDCDFR
LIRRHVFDDIELESDSGTICLELVKKLQDAGYRFAEVPVHHYHRTYGKSQFFNFPRLWRTFVQLIGLWWKLVVRREHMRK
RKKRLAPEEIAR
>Mature_252_residues
MDKRPSISVFFPACNDAGTIGSMVVAAIETLEEITDDYEVIVVENGSTDYTVDVLESLAKRYDRLRVYTHRQALGYGGAL
RVGFAKATKDLIFYTDGDAQYDPRELKLLLPALRDDIDIVNGWKIDRGDPLHRIIIGRIYHHTVKFLFGFKLRDVDCDFR
LIRRHVFDDIELESDSGTICLELVKKLQDAGYRFAEVPVHHYHRTYGKSQFFNFPRLWRTFVQLIGLWWKLVVRREHMRK
RKKRLAPEEIAR

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=214, Percent_Identity=27.5700934579439, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1788588, Length=228, Percent_Identity=25.4385964912281, Blast_Score=84, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI71999402, Length=222, Percent_Identity=26.1261261261261, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24585265, Length=214, Percent_Identity=26.1682242990654, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022857
- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.7.8.30 [H]

Molecular weight: Translated: 29449; Mature: 29449

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKRPSISVFFPACNDAGTIGSMVVAAIETLEEITDDYEVIVVENGSTDYTVDVLESLAK
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHH
RYDRLRVYTHRQALGYGGALRVGFAKATKDLIFYTDGDAQYDPRELKLLLPALRDDIDIV
HHHHHHHHHHHHHHCCCCEEEEHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCC
NGWKIDRGDPLHRIIIGRIYHHTVKFLFGFKLRDVDCDFRLIRRHVFDDIELESDSGTIC
CCEECCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHCCCCEEECCCCHHH
LELVKKLQDAGYRFAEVPVHHYHRTYGKSQFFNFPRLWRTFVQLIGLWWKLVVRREHMRK
HHHHHHHHHCCCEEEECCHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RKKRLAPEEIAR
HHHCCCHHHHCC
>Mature Secondary Structure
MDKRPSISVFFPACNDAGTIGSMVVAAIETLEEITDDYEVIVVENGSTDYTVDVLESLAK
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHH
RYDRLRVYTHRQALGYGGALRVGFAKATKDLIFYTDGDAQYDPRELKLLLPALRDDIDIV
HHHHHHHHHHHHHHCCCCEEEEHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCC
NGWKIDRGDPLHRIIIGRIYHHTVKFLFGFKLRDVDCDFRLIRRHVFDDIELESDSGTIC
CCEECCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHCCCCEEECCCCHHH
LELVKKLQDAGYRFAEVPVHHYHRTYGKSQFFNFPRLWRTFVQLIGLWWKLVVRREHMRK
HHHHHHHHHCCCEEEECCHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RKKRLAPEEIAR
HHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12219091 [H]