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The map label for this gene is serC [H]

Identifier: 222524361

GI number: 222524361

Start: 1377299

End: 1378381

Strand: Reverse

Name: serC [H]

Synonym: Chy400_1084

Alternate gene names: 222524361

Gene position: 1378381-1377299 (Counterclockwise)

Preceding gene: 222524364

Following gene: 222524360

Centisome position: 26.16

GC content: 60.2

Gene sequence:

>1083_bases
ATGATTCACAACTTCAATCCCGGCCCGGCAGCGTTGCCGCCTGACGTAATCGCACGTGCGCAGGCGGAACTGGCTGATTA
CCACGGCTGTGGGATGTCCGTTCTTGAAATAAGTCATCGCAGCAAGGAATACGAGGCAATCAATGCGGCAGCGGAAGCCA
ATCTGAAGGCGCTGCTGGGTCTGGGTGACGATTATCGCGTGTTGTTTATGCAGGGCGGCGCCTCGATGCAATTTGCCCTG
ATCCCGCTCAACCTGTTGCCTGCCGGTGCCACTGCTGAGTATATCGTCACCGGTACCTGGGGCGAGAAGGCGTATGAAGA
GGCGCAGCGGGTCGGTGCGGTGCGGTTGCTGGCAAGCACAGCCGCCGATGGCTACCGCAGTTTGCCGTCCATCGATGCCA
TTACGCCTGACCCACAGGCGGCCTATCTCCACCTTACCACTAACGAGACGATTCAGGGGGTGCAGTGGCCGGCTGAGCTG
CCCGATCTCGGTTCGGTACCGCTGGTCGCCGATATGAGCAGTGATTTTCTCTCGCGGCCATTCCCGGCGCAGCGCTTCGC
GCTGATCTACGCCGGTGCGCAGAAGAACCTGGGGCCGGCGGGTGTTACTGTGGTCGTGATTCGGCAGGATATGATCGAGC
GCGGACGCAAAGACCTGCCGGTCATTATGCGCTATGCCACGTTCGCCAAAAACAATTCGCTTTACAACACGCCACCCGTC
TTTGCGGTGTATATGGTGAATCTGGTGTTGGAGTGGATCAAGGATCAGGGTGGATTGGCGGCGATGGCCGAACGGAACGC
CCGCAAGGCGGCACTGGTCTACGCCGCGATTGATGGTAGCGATGGCTTCTACAGCGGTCACGCGGTGCCGGCAGCACGTT
CGCTGATGAATGTAACCTTCCGTCTGCCCACGCCCGAACTGGAAAAGCAATTTCTGAATGAAGCCCAGGCCGCCGGGATG
GTCGGGCTGGCCGGTCATCGTTCGGTAGGCGGCATTCGCGCATCGCTGTACAACGCGGTCGCGCCGGAGTCGGCGGCAGC
CCTGGCCGACTTTATGCAAGACTTCGCCAAACGCCATGGATGA

Upstream 100 bases:

>100_bases
ACAAGTACCTGCATACTCCTTCCTTCTAGGTAAGCACGTTACCATTTCGAGTATACTATGTTTCACAGCGAGCCTGCTCG
AAAGGATAAAGGGGGACATC

Downstream 100 bases:

>100_bases
GCATCCTTACGCGGCAGCCATCACCTTCATCCCGGTCACCGATTTGCAGGCGAGTGCACGGTGTTACGCCGATGCACTCG
GCCTGCCGCTGGTGCTGGAT

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MIHNFNPGPAALPPDVIARAQAELADYHGCGMSVLEISHRSKEYEAINAAAEANLKALLGLGDDYRVLFMQGGASMQFAL
IPLNLLPAGATAEYIVTGTWGEKAYEEAQRVGAVRLLASTAADGYRSLPSIDAITPDPQAAYLHLTTNETIQGVQWPAEL
PDLGSVPLVADMSSDFLSRPFPAQRFALIYAGAQKNLGPAGVTVVVIRQDMIERGRKDLPVIMRYATFAKNNSLYNTPPV
FAVYMVNLVLEWIKDQGGLAAMAERNARKAALVYAAIDGSDGFYSGHAVPAARSLMNVTFRLPTPELEKQFLNEAQAAGM
VGLAGHRSVGGIRASLYNAVAPESAAALADFMQDFAKRHG

Sequences:

>Translated_360_residues
MIHNFNPGPAALPPDVIARAQAELADYHGCGMSVLEISHRSKEYEAINAAAEANLKALLGLGDDYRVLFMQGGASMQFAL
IPLNLLPAGATAEYIVTGTWGEKAYEEAQRVGAVRLLASTAADGYRSLPSIDAITPDPQAAYLHLTTNETIQGVQWPAEL
PDLGSVPLVADMSSDFLSRPFPAQRFALIYAGAQKNLGPAGVTVVVIRQDMIERGRKDLPVIMRYATFAKNNSLYNTPPV
FAVYMVNLVLEWIKDQGGLAAMAERNARKAALVYAAIDGSDGFYSGHAVPAARSLMNVTFRLPTPELEKQFLNEAQAAGM
VGLAGHRSVGGIRASLYNAVAPESAAALADFMQDFAKRHG
>Mature_360_residues
MIHNFNPGPAALPPDVIARAQAELADYHGCGMSVLEISHRSKEYEAINAAAEANLKALLGLGDDYRVLFMQGGASMQFAL
IPLNLLPAGATAEYIVTGTWGEKAYEEAQRVGAVRLLASTAADGYRSLPSIDAITPDPQAAYLHLTTNETIQGVQWPAEL
PDLGSVPLVADMSSDFLSRPFPAQRFALIYAGAQKNLGPAGVTVVVIRQDMIERGRKDLPVIMRYATFAKNNSLYNTPPV
FAVYMVNLVLEWIKDQGGLAAMAERNARKAALVYAAIDGSDGFYSGHAVPAARSLMNVTFRLPTPELEKQFLNEAQAAGM
VGLAGHRSVGGIRASLYNAVAPESAAALADFMQDFAKRHG

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=362, Percent_Identity=45.8563535911602, Blast_Score=330, Evalue=9e-91,
Organism=Homo sapiens, GI10863955, Length=358, Percent_Identity=41.340782122905, Blast_Score=282, Evalue=4e-76,
Organism=Escherichia coli, GI1787136, Length=361, Percent_Identity=44.8753462603878, Blast_Score=315, Evalue=4e-87,
Organism=Caenorhabditis elegans, GI17506897, Length=360, Percent_Identity=43.6111111111111, Blast_Score=317, Evalue=8e-87,
Organism=Saccharomyces cerevisiae, GI6324758, Length=388, Percent_Identity=36.0824742268041, Blast_Score=250, Evalue=3e-67,
Organism=Drosophila melanogaster, GI21356589, Length=365, Percent_Identity=46.027397260274, Blast_Score=327, Evalue=5e-90,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 38577; Mature: 38577

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHNFNPGPAALPPDVIARAQAELADYHGCGMSVLEISHRSKEYEAINAAAEANLKALLG
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHCCCCEEEE
LGDDYRVLFMQGGASMQFALIPLNLLPAGATAEYIVTGTWGEKAYEEAQRVGAVRLLAST
CCCCEEEEEEECCCCEEEEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
AADGYRSLPSIDAITPDPQAAYLHLTTNETIQGVQWPAELPDLGSVPLVADMSSDFLSRP
HCCHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCHHHHCCC
FPAQRFALIYAGAQKNLGPAGVTVVVIRQDMIERGRKDLPVIMRYATFAKNNSLYNTPPV
CCHHHEEEEEECCCCCCCCCCEEEEEEEHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHH
FAVYMVNLVLEWIKDQGGLAAMAERNARKAALVYAAIDGSDGFYSGHAVPAARSLMNVTF
HHHHHHHHHHHHHHCCCCEEHHHHCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHEEEE
RLPTPELEKQFLNEAQAAGMVGLAGHRSVGGIRASLYNAVAPESAAALADFMQDFAKRHG
ECCCHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIHNFNPGPAALPPDVIARAQAELADYHGCGMSVLEISHRSKEYEAINAAAEANLKALLG
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHCCCCEEEE
LGDDYRVLFMQGGASMQFALIPLNLLPAGATAEYIVTGTWGEKAYEEAQRVGAVRLLAST
CCCCEEEEEEECCCCEEEEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
AADGYRSLPSIDAITPDPQAAYLHLTTNETIQGVQWPAELPDLGSVPLVADMSSDFLSRP
HCCHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCHHHHCCC
FPAQRFALIYAGAQKNLGPAGVTVVVIRQDMIERGRKDLPVIMRYATFAKNNSLYNTPPV
CCHHHEEEEEECCCCCCCCCCEEEEEEEHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHH
FAVYMVNLVLEWIKDQGGLAAMAERNARKAALVYAAIDGSDGFYSGHAVPAARSLMNVTF
HHHHHHHHHHHHHHCCCCEEHHHHCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHEEEE
RLPTPELEKQFLNEAQAAGMVGLAGHRSVGGIRASLYNAVAPESAAALADFMQDFAKRHG
ECCCHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA