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The map label for this gene is typA [H]

Identifier: 222524177

GI number: 222524177

Start: 1129894

End: 1131735

Strand: Direct

Name: typA [H]

Synonym: Chy400_0896

Alternate gene names: 222524177

Gene position: 1129894-1131735 (Clockwise)

Preceding gene: 222524167

Following gene: 222524178

Centisome position: 21.44

GC content: 60.64

Gene sequence:

>1842_bases
ATGATTCAGCGAACTGATTTACGGAATATCGCGATTATTGCGCACGTTGACCACGGCAAGACCACCCTGGTCGATGCGAT
GTTGAAGCAGAGCCGAATCTTCCGCCAGAACCAGCAGGTGGAAGAGCGCGTGCTTGACAGCAATGCGCTGGAACGCGAAC
GAGGTATCACCATTCTGGCGAAGAACACCGCGGTGAACTACCGCGGCGTGAAGATCAACATCGTCGACACACCCGGCCAC
GCCGACTTCGGCGGCGAGGTGGAACGGGTGATGAATATGGTTGACGGCGTGCTCCTGCTGGTCGACGCGGTCGATGGCCC
GATGCCGCAAACCAAGTTTGTGTTGCGCAAAGCGTTGCAGGCCGGCCACCACGCCATCGTCGTCGTCAATAAGATCGACC
GGCCCCAGGCCCGCCCCAACCACGTCGTCAACGAGACGTTCGATCTCTTCGTCGATCTCGGTGCCACCGACGAACAGGCC
GAATTTGCCACCATCTACACCAACGCCCTCCTCGGTCACGCCGGTCGTTCGCCGCTCAAGCTACACGACTCGCTGGAACC
GCTCTTCGAGTGCATTCTCGACCGCATCCCACCACCAACGGTTGACGTTGAAGGACCGGTGCAGTTCCTCGTCACCACCA
GCAGCTACGACGAATACAAGGGCAAGATTCTGACCGGACGACTGGTGCGAGGGACGATCCGCAAAGGCCAGCCACTCGTG
CGGATTGCCCGCGATGGTACCATCTCGCCGGTTAAGGTCAGCCAGATTTTCGTCTACAACGGCCTTGAGCGCCAGGAAGT
GGAACAGGCCCAGGCCGGCGACATCATCGCCATTGCCGGGATTAGCGATGCGGCTATCGGCGACACCATTGCCGATGCCC
TGGCCCCCGAAGCGCTGCCGCCGATCAAAGTCGAAGAGCCGACCGTGCGCATGACCTTCGGCGTCAACACCAGCCCCTTC
GCCGGGCGCGAAGGTACTTACGTAACCTCGCGCAAGCTGCGCGAGCGCCTCTTCCAGGAGATGGAGCGCGATGTAGCGCT
GCGCGTTGAGGAGACCGACAGCCCCGATGTCTTTATCGTCGCCGGACGGGGTGAGTTGCATTTGGGCATTTTGATCGAGA
CCATGCGCCGCGAGGGCTACGAGTTTCAGGTCTCGAAACCCGAAGTGATCTTCCGCGAAGCACCGGATGGAACGCGCCTC
GAACCGATGGAGCTGGTCGAGATTGAAGTGGCGAGTGAATATCAGGGGGTGGTGGTCGAACTGCTCGGCAAACGCCAGGG
GCAGATGCGCGATATGCGAATTTCAGAAGACGGTTCTGTGCATTACGTCTATCTCGTACCGACCCGCGGCCTGCTCGGCT
TTCGCCAGCTCTTCCTGACGGCGACACGCGGCACCGGCATAATGCACAGCATCTTCTTCGGCTACGAACCGTATGCCGGC
GAGATCGAAATGCGCGCCAACGGCAGCCTGATCGCGGCAGAGAGCGGCGTCGCCACCACCTACGCCATCCACGCCCTGCA
AGATCGCGGCGTCTTCTTCATCACCCCTGGTCAAGAGGTGTACGAAGGCATGGTCGTCGGGCAACACATCCGCGACAACG
ACCTGGAAGTCAACGTCTGCAAGGAAAAGCATCTCACCAACATGCGCAACAACCGTGGCGCCGAAACGATCCGGCTCGAT
GCGCCGCGCCAGCTCTCGCTTGACGATGCCATCGAATACATCAGCGACGATGAGCTGGTCGAGGTGACACCCAAAGGCTG
GCGCATTCGCAAACGCCTGCTCAGCTCCGATGACCGTCGGCGCGAGAAGAAGCGGCGCGAACTCGCCCTCAGCGAACGCT
AA

Upstream 100 bases:

>100_bases
CCACCCTAACGTTATGGTATAATGCATGTAGCATCGTCGCGCTCAGGTTGAACCTGAGCGTTTTTTGCGCCAACCAACGG
CCAACACTAACGGAACAGGT

Downstream 100 bases:

>100_bases
AATACTCATCCTTTTCTCATTTTTCTTTAACCTTCTCTTTATGCTGCCCGTCGATACTATGGGGCGACGGGCAGCGTGCA
TCTGTATCTGCACCCGGAAA

Product: GTP-binding protein TypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 613; Mature: 613

Protein sequence:

>613_residues
MIQRTDLRNIAIIAHVDHGKTTLVDAMLKQSRIFRQNQQVEERVLDSNALERERGITILAKNTAVNYRGVKINIVDTPGH
ADFGGEVERVMNMVDGVLLLVDAVDGPMPQTKFVLRKALQAGHHAIVVVNKIDRPQARPNHVVNETFDLFVDLGATDEQA
EFATIYTNALLGHAGRSPLKLHDSLEPLFECILDRIPPPTVDVEGPVQFLVTTSSYDEYKGKILTGRLVRGTIRKGQPLV
RIARDGTISPVKVSQIFVYNGLERQEVEQAQAGDIIAIAGISDAAIGDTIADALAPEALPPIKVEEPTVRMTFGVNTSPF
AGREGTYVTSRKLRERLFQEMERDVALRVEETDSPDVFIVAGRGELHLGILIETMRREGYEFQVSKPEVIFREAPDGTRL
EPMELVEIEVASEYQGVVVELLGKRQGQMRDMRISEDGSVHYVYLVPTRGLLGFRQLFLTATRGTGIMHSIFFGYEPYAG
EIEMRANGSLIAAESGVATTYAIHALQDRGVFFITPGQEVYEGMVVGQHIRDNDLEVNVCKEKHLTNMRNNRGAETIRLD
APRQLSLDDAIEYISDDELVEVTPKGWRIRKRLLSSDDRRREKKRRELALSER

Sequences:

>Translated_613_residues
MIQRTDLRNIAIIAHVDHGKTTLVDAMLKQSRIFRQNQQVEERVLDSNALERERGITILAKNTAVNYRGVKINIVDTPGH
ADFGGEVERVMNMVDGVLLLVDAVDGPMPQTKFVLRKALQAGHHAIVVVNKIDRPQARPNHVVNETFDLFVDLGATDEQA
EFATIYTNALLGHAGRSPLKLHDSLEPLFECILDRIPPPTVDVEGPVQFLVTTSSYDEYKGKILTGRLVRGTIRKGQPLV
RIARDGTISPVKVSQIFVYNGLERQEVEQAQAGDIIAIAGISDAAIGDTIADALAPEALPPIKVEEPTVRMTFGVNTSPF
AGREGTYVTSRKLRERLFQEMERDVALRVEETDSPDVFIVAGRGELHLGILIETMRREGYEFQVSKPEVIFREAPDGTRL
EPMELVEIEVASEYQGVVVELLGKRQGQMRDMRISEDGSVHYVYLVPTRGLLGFRQLFLTATRGTGIMHSIFFGYEPYAG
EIEMRANGSLIAAESGVATTYAIHALQDRGVFFITPGQEVYEGMVVGQHIRDNDLEVNVCKEKHLTNMRNNRGAETIRLD
APRQLSLDDAIEYISDDELVEVTPKGWRIRKRLLSSDDRRREKKRRELALSER
>Mature_613_residues
MIQRTDLRNIAIIAHVDHGKTTLVDAMLKQSRIFRQNQQVEERVLDSNALERERGITILAKNTAVNYRGVKINIVDTPGH
ADFGGEVERVMNMVDGVLLLVDAVDGPMPQTKFVLRKALQAGHHAIVVVNKIDRPQARPNHVVNETFDLFVDLGATDEQA
EFATIYTNALLGHAGRSPLKLHDSLEPLFECILDRIPPPTVDVEGPVQFLVTTSSYDEYKGKILTGRLVRGTIRKGQPLV
RIARDGTISPVKVSQIFVYNGLERQEVEQAQAGDIIAIAGISDAAIGDTIADALAPEALPPIKVEEPTVRMTFGVNTSPF
AGREGTYVTSRKLRERLFQEMERDVALRVEETDSPDVFIVAGRGELHLGILIETMRREGYEFQVSKPEVIFREAPDGTRL
EPMELVEIEVASEYQGVVVELLGKRQGQMRDMRISEDGSVHYVYLVPTRGLLGFRQLFLTATRGTGIMHSIFFGYEPYAG
EIEMRANGSLIAAESGVATTYAIHALQDRGVFFITPGQEVYEGMVVGQHIRDNDLEVNVCKEKHLTNMRNNRGAETIRLD
APRQLSLDDAIEYISDDELVEVTPKGWRIRKRLLSSDDRRREKKRRELALSER

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=488, Percent_Identity=29.3032786885246, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI94966754, Length=151, Percent_Identity=38.4105960264901, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI34147630, Length=280, Percent_Identity=33.2142857142857, Blast_Score=106, Evalue=8e-23,
Organism=Homo sapiens, GI4503483, Length=150, Percent_Identity=35.3333333333333, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI18390331, Length=150, Percent_Identity=38, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI25306287, Length=139, Percent_Identity=38.1294964028777, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI19923640, Length=139, Percent_Identity=38.1294964028777, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI25306283, Length=139, Percent_Identity=38.1294964028777, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI53729339, Length=276, Percent_Identity=30.4347826086957, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI53729337, Length=276, Percent_Identity=30.4347826086957, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI310132016, Length=112, Percent_Identity=36.6071428571429, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI310110807, Length=112, Percent_Identity=36.6071428571429, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI310123363, Length=112, Percent_Identity=36.6071428571429, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI217272894, Length=188, Percent_Identity=29.2553191489362, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI217272892, Length=188, Percent_Identity=29.2553191489362, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI94966752, Length=147, Percent_Identity=29.2517006802721, Blast_Score=73, Evalue=1e-12,
Organism=Escherichia coli, GI48994988, Length=605, Percent_Identity=52.2314049586777, Blast_Score=624, Evalue=1e-180,
Organism=Escherichia coli, GI1788922, Length=502, Percent_Identity=29.8804780876494, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1789738, Length=147, Percent_Identity=39.4557823129252, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1790835, Length=144, Percent_Identity=29.1666666666667, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790412, Length=134, Percent_Identity=35.8208955223881, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1789737, Length=134, Percent_Identity=35.8208955223881, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1789559, Length=136, Percent_Identity=34.5588235294118, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17557151, Length=322, Percent_Identity=31.055900621118, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71988811, Length=128, Percent_Identity=36.71875, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI71988819, Length=128, Percent_Identity=36.71875, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17506493, Length=164, Percent_Identity=34.1463414634146, Blast_Score=99, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17556745, Length=135, Percent_Identity=38.5185185185185, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17533571, Length=138, Percent_Identity=40.5797101449275, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17556456, Length=282, Percent_Identity=30.4964539007092, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17552882, Length=134, Percent_Identity=32.8358208955224, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994658, Length=235, Percent_Identity=31.9148936170213, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25141371, Length=295, Percent_Identity=27.1186440677966, Blast_Score=74, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323320, Length=530, Percent_Identity=28.1132075471698, Blast_Score=142, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324761, Length=270, Percent_Identity=32.2222222222222, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6324707, Length=152, Percent_Identity=38.1578947368421, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320593, Length=152, Percent_Identity=38.1578947368421, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6322359, Length=150, Percent_Identity=37.3333333333333, Blast_Score=95, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6323098, Length=142, Percent_Identity=38.0281690140845, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324166, Length=142, Percent_Identity=38.0281690140845, Blast_Score=87, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6324550, Length=145, Percent_Identity=32.4137931034483, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI78706572, Length=521, Percent_Identity=26.295585412668, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21357743, Length=187, Percent_Identity=35.2941176470588, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24585709, Length=156, Percent_Identity=35.8974358974359, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24585711, Length=156, Percent_Identity=35.8974358974359, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24585713, Length=156, Percent_Identity=35.8974358974359, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28574573, Length=141, Percent_Identity=38.2978723404255, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24582462, Length=144, Percent_Identity=38.1944444444444, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281363316, Length=272, Percent_Identity=29.0441176470588, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17864358, Length=272, Percent_Identity=29.0441176470588, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI19921738, Length=286, Percent_Identity=30.0699300699301, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28572034, Length=285, Percent_Identity=30.1754385964912, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI221458488, Length=146, Percent_Identity=38.3561643835616, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 68595; Mature: 68595

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQRTDLRNIAIIAHVDHGKTTLVDAMLKQSRIFRQNQQVEERVLDSNALERERGITILA
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCEEEEE
KNTAVNYRGVKINIVDTPGHADFGGEVERVMNMVDGVLLLVDAVDGPMPQTKFVLRKALQ
ECCEEEECCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHH
AGHHAIVVVNKIDRPQARPNHVVNETFDLFVDLGATDEQAEFATIYTNALLGHAGRSPLK
CCCEEEEEEECCCCCCCCCCCHHCCCEEEEEECCCCCCCCCEEEEHHHHHHHCCCCCCCC
LHDSLEPLFECILDRIPPPTVDVEGPVQFLVTTSSYDEYKGKILTGRLVRGTIRKGQPLV
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCEEEECCEEECHHCCCCCEE
RIARDGTISPVKVSQIFVYNGLERQEVEQAQAGDIIAIAGISDAAIGDTIADALAPEALP
EEECCCCCCCEEEEEEEEECCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCC
PIKVEEPTVRMTFGVNTSPFAGREGTYVTSRKLRERLFQEMERDVALRVEETDSPDVFIV
CCCCCCCEEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEE
AGRGELHLGILIETMRREGYEFQVSKPEVIFREAPDGTRLEPMELVEIEVASEYQGVVVE
ECCCCEEEHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCCEEEEEEEECCCCCHHHHH
LLGKRQGQMRDMRISEDGSVHYVYLVPTRGLLGFRQLFLTATRGTGIMHSIFFGYEPYAG
HHCCCCCCCCCEEECCCCCEEEEEEECCCCHHHHHHHHEEECCCCCHHHHHHHCCCCCCC
EIEMRANGSLIAAESGVATTYAIHALQDRGVFFITPGQEVYEGMVVGQHIRDNDLEVNVC
EEEEECCCCEEEECCCCEEEEEEEEECCCCEEEECCCHHHHHHHHCCCCCCCCCCEEEEE
KEKHLTNMRNNRGAETIRLDAPRQLSLDDAIEYISDDELVEVTPKGWRIRKRLLSSDDRR
HHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHCCCCCEEEECCCCHHHHHHHHCCHHHH
REKKRRELALSER
HHHHHHHCCCCCC
>Mature Secondary Structure
MIQRTDLRNIAIIAHVDHGKTTLVDAMLKQSRIFRQNQQVEERVLDSNALERERGITILA
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCEEEEE
KNTAVNYRGVKINIVDTPGHADFGGEVERVMNMVDGVLLLVDAVDGPMPQTKFVLRKALQ
ECCEEEECCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHH
AGHHAIVVVNKIDRPQARPNHVVNETFDLFVDLGATDEQAEFATIYTNALLGHAGRSPLK
CCCEEEEEEECCCCCCCCCCCHHCCCEEEEEECCCCCCCCCEEEEHHHHHHHCCCCCCCC
LHDSLEPLFECILDRIPPPTVDVEGPVQFLVTTSSYDEYKGKILTGRLVRGTIRKGQPLV
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCEEEECCEEECHHCCCCCEE
RIARDGTISPVKVSQIFVYNGLERQEVEQAQAGDIIAIAGISDAAIGDTIADALAPEALP
EEECCCCCCCEEEEEEEEECCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCC
PIKVEEPTVRMTFGVNTSPFAGREGTYVTSRKLRERLFQEMERDVALRVEETDSPDVFIV
CCCCCCCEEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEE
AGRGELHLGILIETMRREGYEFQVSKPEVIFREAPDGTRLEPMELVEIEVASEYQGVVVE
ECCCCEEEHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCCEEEEEEEECCCCCHHHHH
LLGKRQGQMRDMRISEDGSVHYVYLVPTRGLLGFRQLFLTATRGTGIMHSIFFGYEPYAG
HHCCCCCCCCCEEECCCCCEEEEEEECCCCHHHHHHHHEEECCCCCHHHHHHHCCCCCCC
EIEMRANGSLIAAESGVATTYAIHALQDRGVFFITPGQEVYEGMVVGQHIRDNDLEVNVC
EEEEECCCCEEEECCCCEEEEEEEEECCCCEEEECCCHHHHHHHHCCCCCCCCCCEEEEE
KEKHLTNMRNNRGAETIRLDAPRQLSLDDAIEYISDDELVEVTPKGWRIRKRLLSSDDRR
HHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHCCCCCEEEECCCCHHHHHHHHCCHHHH
REKKRRELALSER
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]