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The map label for this gene is cry2 [H]

Identifier: 222524057

GI number: 222524057

Start: 970097

End: 971629

Strand: Direct

Name: cry2 [H]

Synonym: Chy400_0772

Alternate gene names: 222524057

Gene position: 970097-971629 (Clockwise)

Preceding gene: 222524056

Following gene: 222524060

Centisome position: 18.41

GC content: 64.77

Gene sequence:

>1533_bases
ATGTATATACAACTCGTCTGGTTCAAGCGTGATCTCCGCCTTCACGACCATCCGGCTCTAAGCGCCGCCGCTGCCCGTGG
CCCGGTGCTCCCGCTCTACATCGTCGAACCATCGCTCATCCACGCACCCGATTTCGCGGCCCGACACTGGACATTCATTC
GCGGGTGTCTGGTTGAACTGCGAGCAAACCTGGCCCGCCTTGGTCAGCCGCTGGTGGTGCGGGTTGGCGAGGCGGTTGAG
GTGCTTGATCACCTGGTCAGCACCTGGCCGATTGAAGCGATCTGGGCGCACGAGGAGACCGGTAATCTGCTCAGTTATGC
CCGCGACCGGGCAGTCCGGCGTTGGGCCCGCGCACGTGGGATTCCGTTTCACGAGCTGCCGCAGAACGGGGTAGTGCGTC
GGTTGCCGTCGCGTGATGAGTGGCAGGCCCGCTGGGAAGAGCGCATGGCAGCCGCGCAGGCCCAGCCTCCATCGGCCTTA
CCGCCACTCGCCATTGATCCGGGAACCATTCCTACTGCCGACGAACTCTCGTTGCCGCCCGACACGCTCAGCGAGCATCA
GCCGGCGGGAGAGACTGCGGCCCTACAGACGCTCACCGACTTTATCCACCGGCGCAGTCAACAATACCATCGCGCCCTCG
CCAGTCCGCTAACCGCCTGGGAAGGCTGTTCCCGCCTGAGTGCTTATCTGGCCTGGGGAGCACTGTCCATTCGTACCGTC
GTCCAGGCGACCCGCCACCGGATTTCTGAACTCGCGTTTGATCCGTCACCGGCGACCCGGGGCTGGGTGCGGGCGCTGAA
TGCCTTTGAGTCACGGCTGCACTGGCACTGCCATTTCATTCAGAAGCTGGAAGACGAGCCGGAGATCGAAGTCCGCAATC
TGGTGCGGGCTTACGACGGTATGCGCGAAGAAAACCACCGCCCTGATCTGCTCGTGGCCTGGGCCAGTGGCCGCACCGGC
TACCCATTCGTCGACGCCTGTATGCGTGCGCTCACCGCGACCGGCTGGCTCAATTTTCGGATGCGGGCCATGCTGGTCAG
CTTTGTGGCCTACGACCTGTGGCAGCACTGGCGCGAACCGGCGCTGATTCTGGCCCGCCGCTGGATCGACTACGAACCGG
GCATTCACTACAGCCAGATGCAGATGCAGGCGGGTACTTCGGGCAACCGCACCATTCGCATCTACAACCCCGTCAAACAG
GGCATCGATCACGACCCCGAAGGCATCTTTATCCGCCGCTGGGTGCCCGAACTGGCGCACGTCCCCACGCCCTACATCCA
CACCCCCTGGTTGCTCGACCGTCACGGACAAGAGCGGGCCGGCTGTCGGATCGGGCGCGACTACCCGGCGCCAATTGTCG
ATCACGAGGCTGCCTACCGACGCGCCCGCGCTGCGATTGCCGCCGTGCGTGCCCGACCCGAAACCGCCCAGGAAGCGGCG
GCAGTCCATCAACGCCACGGCTCGCGCACCTGGCGCCCGCAGCGCCGCCCGTCCAAAACCGTCTCCAGCCGCCAGCTCAG
GCTGGACTTATGA

Upstream 100 bases:

>100_bases
CCGCACCCAACCCCGTCCGCCCCCAAAACCGTGGTACCATACATAATGAAGCTATTGGCGTAACGGTAGTGCCCAATCAG
TCGCTTACTCAACTGCGCAG

Downstream 100 bases:

>100_bases
GGTATACCGCACCAAAGCCCAGACAATAGCGCCGGCAGCCACCACGTGCATCAGATTCAACACCATCTGCTCAAGCAGAC
TGACCGGCAGCGTAAACGGG

Product: deoxyribodipyrimidine photo-lyase

Products: 2 pyrimidine residues (in DNA) [C]

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MYIQLVWFKRDLRLHDHPALSAAAARGPVLPLYIVEPSLIHAPDFAARHWTFIRGCLVELRANLARLGQPLVVRVGEAVE
VLDHLVSTWPIEAIWAHEETGNLLSYARDRAVRRWARARGIPFHELPQNGVVRRLPSRDEWQARWEERMAAAQAQPPSAL
PPLAIDPGTIPTADELSLPPDTLSEHQPAGETAALQTLTDFIHRRSQQYHRALASPLTAWEGCSRLSAYLAWGALSIRTV
VQATRHRISELAFDPSPATRGWVRALNAFESRLHWHCHFIQKLEDEPEIEVRNLVRAYDGMREENHRPDLLVAWASGRTG
YPFVDACMRALTATGWLNFRMRAMLVSFVAYDLWQHWREPALILARRWIDYEPGIHYSQMQMQAGTSGNRTIRIYNPVKQ
GIDHDPEGIFIRRWVPELAHVPTPYIHTPWLLDRHGQERAGCRIGRDYPAPIVDHEAAYRRARAAIAAVRARPETAQEAA
AVHQRHGSRTWRPQRRPSKTVSSRQLRLDL

Sequences:

>Translated_510_residues
MYIQLVWFKRDLRLHDHPALSAAAARGPVLPLYIVEPSLIHAPDFAARHWTFIRGCLVELRANLARLGQPLVVRVGEAVE
VLDHLVSTWPIEAIWAHEETGNLLSYARDRAVRRWARARGIPFHELPQNGVVRRLPSRDEWQARWEERMAAAQAQPPSAL
PPLAIDPGTIPTADELSLPPDTLSEHQPAGETAALQTLTDFIHRRSQQYHRALASPLTAWEGCSRLSAYLAWGALSIRTV
VQATRHRISELAFDPSPATRGWVRALNAFESRLHWHCHFIQKLEDEPEIEVRNLVRAYDGMREENHRPDLLVAWASGRTG
YPFVDACMRALTATGWLNFRMRAMLVSFVAYDLWQHWREPALILARRWIDYEPGIHYSQMQMQAGTSGNRTIRIYNPVKQ
GIDHDPEGIFIRRWVPELAHVPTPYIHTPWLLDRHGQERAGCRIGRDYPAPIVDHEAAYRRARAAIAAVRARPETAQEAA
AVHQRHGSRTWRPQRRPSKTVSSRQLRLDL
>Mature_510_residues
MYIQLVWFKRDLRLHDHPALSAAAARGPVLPLYIVEPSLIHAPDFAARHWTFIRGCLVELRANLARLGQPLVVRVGEAVE
VLDHLVSTWPIEAIWAHEETGNLLSYARDRAVRRWARARGIPFHELPQNGVVRRLPSRDEWQARWEERMAAAQAQPPSAL
PPLAIDPGTIPTADELSLPPDTLSEHQPAGETAALQTLTDFIHRRSQQYHRALASPLTAWEGCSRLSAYLAWGALSIRTV
VQATRHRISELAFDPSPATRGWVRALNAFESRLHWHCHFIQKLEDEPEIEVRNLVRAYDGMREENHRPDLLVAWASGRTG
YPFVDACMRALTATGWLNFRMRAMLVSFVAYDLWQHWREPALILARRWIDYEPGIHYSQMQMQAGTSGNRTIRIYNPVKQ
GIDHDPEGIFIRRWVPELAHVPTPYIHTPWLLDRHGQERAGCRIGRDYPAPIVDHEAAYRRARAAIAAVRARPETAQEAA
AVHQRHGSRTWRPQRRPSKTVSSRQLRLDL

Specific function: Has no photolyase activity [H]

COG id: COG0415

COG function: function code L; Deoxyribodipyrimidine photolyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DNA photolyase domain [H]

Homologues:

Organism=Homo sapiens, GI4758072, Length=500, Percent_Identity=26.4, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI188536100, Length=490, Percent_Identity=26.530612244898, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI188536103, Length=304, Percent_Identity=28.2894736842105, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1786926, Length=497, Percent_Identity=31.9919517102616, Blast_Score=173, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6324962, Length=261, Percent_Identity=27.5862068965517, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17137248, Length=488, Percent_Identity=27.6639344262295, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24585455, Length=488, Percent_Identity=27.6639344262295, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24648152, Length=517, Percent_Identity=23.4042553191489, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002081
- InterPro:   IPR018394
- InterPro:   IPR006050
- InterPro:   IPR005101
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00875 DNA_photolyase; PF03441 FAD_binding_7 [H]

EC number: 4.1.99.3 [C]

Molecular weight: Translated: 58357; Mature: 58357

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIQLVWFKRDLRLHDHPALSAAAARGPVLPLYIVEPSLIHAPDFAARHWTFIRGCLVEL
CEEEEEEEECCCCCCCCCCHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
RANLARLGQPLVVRVGEAVEVLDHLVSTWPIEAIWAHEETGNLLSYARDRAVRRWARARG
HHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCC
IPFHELPQNGVVRRLPSRDEWQARWEERMAAAQAQPPSALPPLAIDPGTIPTADELSLPP
CCHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DTLSEHQPAGETAALQTLTDFIHRRSQQYHRALASPLTAWEGCSRLSAYLAWGALSIRTV
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQATRHRISELAFDPSPATRGWVRALNAFESRLHWHCHFIQKLEDEPEIEVRNLVRAYDG
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
MREENHRPDLLVAWASGRTGYPFVDACMRALTATGWLNFRMRAMLVSFVAYDLWQHWREP
HHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ALILARRWIDYEPGIHYSQMQMQAGTSGNRTIRIYNPVKQGIDHDPEGIFIRRWVPELAH
HHHHHHHHCCCCCCCCHHHHHHHCCCCCCCEEEEECHHHHCCCCCCCCEEHHHHHHHHHC
VPTPYIHTPWLLDRHGQERAGCRIGRDYPAPIVDHEAAYRRARAAIAAVRARPETAQEAA
CCCCCCCCCHHHCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
AVHQRHGSRTWRPQRRPSKTVSSRQLRLDL
HHHHHCCCCCCCCCCCCCCCCCCCCEEECC
>Mature Secondary Structure
MYIQLVWFKRDLRLHDHPALSAAAARGPVLPLYIVEPSLIHAPDFAARHWTFIRGCLVEL
CEEEEEEEECCCCCCCCCCHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
RANLARLGQPLVVRVGEAVEVLDHLVSTWPIEAIWAHEETGNLLSYARDRAVRRWARARG
HHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCC
IPFHELPQNGVVRRLPSRDEWQARWEERMAAAQAQPPSALPPLAIDPGTIPTADELSLPP
CCHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DTLSEHQPAGETAALQTLTDFIHRRSQQYHRALASPLTAWEGCSRLSAYLAWGALSIRTV
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQATRHRISELAFDPSPATRGWVRALNAFESRLHWHCHFIQKLEDEPEIEVRNLVRAYDG
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
MREENHRPDLLVAWASGRTGYPFVDACMRALTATGWLNFRMRAMLVSFVAYDLWQHWREP
HHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ALILARRWIDYEPGIHYSQMQMQAGTSGNRTIRIYNPVKQGIDHDPEGIFIRRWVPELAH
HHHHHHHHCCCCCCCCHHHHHHHCCCCCCCEEEEECHHHHCCCCCCCCEEHHHHHHHHHC
VPTPYIHTPWLLDRHGQERAGCRIGRDYPAPIVDHEAAYRRARAAIAAVRARPETAQEAA
CCCCCCCCCHHHCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
AVHQRHGSRTWRPQRRPSKTVSSRQLRLDL
HHHHHCCCCCCCCCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: ATP; FADH2; Flavin; pterin [C]

Metal ions: NA

Kcat value (1/min): 2.4 [C]

Specific activity: NA

Km value (mM): NA

Substrates: cyclobutadipyrimidine (in DNA) [C]

Specific reaction: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA) [C]

General reaction: C-C-bond cleavage [C]

Inhibitor: yeast DNA [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]