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The map label for this gene is rsbX [H]

Identifier: 222523786

GI number: 222523786

Start: 587974

End: 588552

Strand: Direct

Name: rsbX [H]

Synonym: Chy400_0494

Alternate gene names: 222523786

Gene position: 587974-588552 (Clockwise)

Preceding gene: 222523785

Following gene: 222523787

Centisome position: 11.16

GC content: 52.33

Gene sequence:

>579_bases
ATGAAACTCTCGTGGGGAGCAGCGCTGCGCCCAAAAGCAGGCCAACACATCAGCGGCGACGCTTATCTGGTCTTACCCTA
TGCTGACAATCAACTGTTAGCTGCCGTTATTGATGGACTTGGCGGTGGCGAGGCGGCTGCTGAAGCAGCCCAGCGCGCTG
TTGCCGTTCTGGAACGATATCCAACGCTTGAATTAACCGAGTTGATGCGCCAGGCTGACCGGGCACTTGTCGGTAGCCGT
GGCGCGGTGATGGCGCTACTTCGTCTCAATGCCGATCAACATACTGCCGAATTTGTGGGTGTTGGGAACGTTGGCGCGCA
GGTGTATAGCGATCTGCTGATAAAACCTATCTCAAAAAACGGGATTGTCGGTTATCGCCTGCCACAACTCCTGCGCCTGA
GTTATACCTACAATTCTGGCGATACCTTCGTTTTATACAGTGACGGTATATCAAGTCGCTTTACTACCGAGATGCCGCCT
GATTTACATCAGTCACCACAACACATTGCCGATGAGATTCTGCATCGCTTTGGCAAGGATAGCGATGATGCAACTGTGGT
TGTGGTACGCAGTGAATAA

Upstream 100 bases:

>100_bases
GCGTCGGTTAATGGATGATTTTCACATCCAATCAACACCAGGTCTTGGAACAACAGTACGTGCAGTGAAGTGGCGGACAA
CACGCCGATAATGAGGAACT

Downstream 100 bases:

>100_bases
CGGAAATTACCGACTCAGCCTATGAATCCCACACTCAGTCAATGGCTGCACACCCGGCAGACAGCTATCCTCGACAACTG
GCCAGATCGAAACGAAGCCA

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: Sigma-B negative effector [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MKLSWGAALRPKAGQHISGDAYLVLPYADNQLLAAVIDGLGGGEAAAEAAQRAVAVLERYPTLELTELMRQADRALVGSR
GAVMALLRLNADQHTAEFVGVGNVGAQVYSDLLIKPISKNGIVGYRLPQLLRLSYTYNSGDTFVLYSDGISSRFTTEMPP
DLHQSPQHIADEILHRFGKDSDDATVVVVRSE

Sequences:

>Translated_192_residues
MKLSWGAALRPKAGQHISGDAYLVLPYADNQLLAAVIDGLGGGEAAAEAAQRAVAVLERYPTLELTELMRQADRALVGSR
GAVMALLRLNADQHTAEFVGVGNVGAQVYSDLLIKPISKNGIVGYRLPQLLRLSYTYNSGDTFVLYSDGISSRFTTEMPP
DLHQSPQHIADEILHRFGKDSDDATVVVVRSE
>Mature_192_residues
MKLSWGAALRPKAGQHISGDAYLVLPYADNQLLAAVIDGLGGGEAAAEAAQRAVAVLERYPTLELTELMRQADRALVGSR
GAVMALLRLNADQHTAEFVGVGNVGAQVYSDLLIKPISKNGIVGYRLPQLLRLSYTYNSGDTFVLYSDGISSRFTTEMPP
DLHQSPQHIADEILHRFGKDSDDATVVVVRSE

Specific function: Negative regulator of sigma-B activity. Dephosphorylates rsbS. Plays a role both in maintaining low sigma-B activity during growth and in reestablishing prestress sigma-B activity after induction. Could have a negative feedback role by indirectly communic

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001932
- InterPro:   IPR010822 [H]

Pfam domain/function: PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 20736; Mature: 20736

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSWGAALRPKAGQHISGDAYLVLPYADNQLLAAVIDGLGGGEAAAEAAQRAVAVLERY
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
PTLELTELMRQADRALVGSRGAVMALLRLNADQHTAEFVGVGNVGAQVYSDLLIKPISKN
CCHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCHHHEEECCCHHHHHHHHHHHCCCCCC
GIVGYRLPQLLRLSYTYNSGDTFVLYSDGISSRFTTEMPPDLHQSPQHIADEILHRFGKD
CEEEECCHHHEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
SDDATVVVVRSE
CCCCEEEEEECC
>Mature Secondary Structure
MKLSWGAALRPKAGQHISGDAYLVLPYADNQLLAAVIDGLGGGEAAAEAAQRAVAVLERY
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
PTLELTELMRQADRALVGSRGAVMALLRLNADQHTAEFVGVGNVGAQVYSDLLIKPISKN
CCHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCHHHEEECCCHHHHHHHHHHHCCCCCC
GIVGYRLPQLLRLSYTYNSGDTFVLYSDGISSRFTTEMPPDLHQSPQHIADEILHRFGKD
CEEEECCHHHEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
SDDATVVVVRSE
CCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2170324; 9384377; 3027048; 1592822; 8468294; 8824586; 9658013 [H]