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The map label for this gene is gacS [H]

Identifier: 222523722

GI number: 222523722

Start: 506422

End: 510465

Strand: Reverse

Name: gacS [H]

Synonym: Chy400_0428

Alternate gene names: 222523722

Gene position: 510465-506422 (Counterclockwise)

Preceding gene: 222523723

Following gene: 222523721

Centisome position: 9.69

GC content: 55.22

Gene sequence:

>4044_bases
ATGGCTCAGTGGTCGCGCAGGGCGCTCATCAGTTTTGGGGTAGTATATGCCGTCTTGATTTGGGTGGGTGCTCAACCACT
GCTGGCTAATCGTGGCATTCCTTTGTTATGGGTAGCCGGCGGATTTGCGGCAGGGGGGGTCTTGCTGGCCGGCAAGCGCC
TCTTGCCGATTATTTTCATTGGAGCATTCATTGCCTACACGGTGGTTTTCCGGCAACTAGGGCTGTCGTCCGAGCGCCTG
CTTGCTGCGGCCCTCGTCTTTGGTCTGAGCGCGATCATCCAGGCCTGGCTGGTGAATTGGCTGGTGCGTCGCTTCGGGAG
AACCTTACCCCCTTCCTCTATCCGCTATACGCTGGTGGTGTGTGGTTTACTGGCACTGGCTGTATTACCGGCACCGTTTC
TAGCTGTGATGGTGCTGGTGGTTGTGCAGCAACCCCTGGTAAGCAGTCCGCCAATAGTTGCTCTGCAATGGTGGCTCAAT
CTGGTCGCCGGAGTCTGGCTCGTCACGCCGTGGATGGTGCTCGGCGAGTACTACCGGCAACGACGGCCAATGCGTGAACC
ATGGTTGTGGCCGGTGAGTAGTCTTTTACTGGCGCTCATGCTGTTCAGTCTGCAACTCATCTGGCGTGATGCCAACCGTC
AGTTTACGACACAACTGCAAGCAGATGTCAACGAGGTGGTGAGTCTGATTAATGATCGGCTGACGATCTATGAGCAGGCG
CTGCTAAGTCAGAGTGCGCTGTTTCTTGCTTCACAACGGGTTGATCAGCATGAATTTAGCGTCTTTAGTCGTACCCAACT
GGCGCGTTTGCCGGCATTACGGGCGGTTAGTTGGATACCACGGATTCCATTGCAGCAACGAACAGCGTTTGAACATGCAA
TGCAGGAGACCGGACTGCCTGATTTCAGGATTCGCGAACCCGATGCAACTGCCAGACCAGCCGATACCCGTGATGAATAC
TATCCAATCACCTACCTGGAACCGTTTGCCCGTCGGCGGGCTGTGCTAGGGCTTGATCTGGCAGCCGATCCGGTGCGGCG
AGCAGCTATCGAACAGGCGCGTGATAGTGGTCAGGTGGTGATAACAGCACCGTTGCAATCGTATCTGGCCAGTGATCCGG
CCCCTGCGGTCTTGTTGTTTGCACCGGTGTACAGTGGCAGCCTGCCACCACAATCGGTGGAAGAACGACGACAACGCATT
CGCGGGATGGTTGCCTTCTTGATTGTACCGGGGGAGGTGATCGAGCAGGCGTTAAGACCGGTGACAACACCTGATCTCGA
ATTTGTCCTGGTTGATGCAACAGAGGAGTCACTACGGCCATTAGCCGTCTTTACCGGTGGCAGAGCTGTTCCTTCACCCT
ACATTTCCGATCTGGATATCGTCATCCGTGATGCAGTGGCAATATCTGATATTCCCCGCTACGGTAGGGTCTGGTCAATC
GCCTTCTGTCTGGGAACAAACTACCTACCGTTCTGGTGGTCGGCGGATGCCATCAGCCGAACGGTACTGGCTATTGCCAG
TGTTGCTATCTTCTTTCTGTTTGTAGCGATTCGGCAGCGCCACGAAGCGCGGCAGCGTCGTTTGACCCGTACCTATGCGT
TGCTGAGTGCGATCAATCAGATGATTATTCGTGAACGTGATCCACAACGCATCTTTCAAGAGGTGTGTCAGGTCGGGATT
GGCGAGGGTGGCTTTCGGTTGGTGTGGATTGGTCGTCATAACCTGGTAACAAGCCGATTCGAGACCATCGCTATACATAG
TGCGAAGGAACTCGATCAGTCACTTGTACACCTGCTCACCGGCGAGCAGTTGGCAATGACACTTTCACCGGTATGTCAGG
GTGATCGGGTCGTTATCAATGACCTCGCTACCGATCCGCGTTGTGCAGCGTGGCGTTCGCAGGCTGTAGCGTATGGTCTA
CGGGCAATGGCCGGTTTCCCGCTGGTAGTGCCTGATGAGCCGCCTGCGGTGTTGTGTTTCTATGCCGGTCAACCCGCGGC
TTTTGACCATGATGAAATACAGTTGCTGGACGAGCTGGTGCGTGACATCATCTTTGGCCTGCTGGTGAGTCAACAAGAGG
CACAACTGCGCACCAGTGAGCAGCGTAATCATCTGATCGTGAGTGCTTTGCCTGATCTGGTATTGCGGTTACGGCCTGAT
GGGCAGGTCGTTGATGTGGTGGCTGCCGAGTCGATGGTATTGCCGATGGCCCCGACAGCGATGATTAACAGCACACTCGA
ACAGCTCTTTCCAGCCGCAATTGCAACGCAGTATCGGCAGGCGCTAAGCGCTGCGTTCGCCTCTGGCGAACTCCAGACAT
TGGCGTATCAGTTGATCGTTGAAGCCAAAGAATATTTCTTCGAGGCGCGCATCAAAGCTGCTTTGCCGGCAGAGGAAGCG
ATTGCAATTGTGCGTGATGTAACGGCGTGGCGCAACGCTGAACTGGCCTTGCAGGTAGAGCGCGATCTCCTGGCGCAGCG
GGTTGCTGAACGTACCGCTGAGTTGCACCGGGCCAATGCGGAACTTCTCCGGGCTGCCCGCACCAAAGATGAATTTCTCG
CCAACATGAGCCACGAGCTGCGCACACCACTCAATTCAATCCTGGCTTTGAGCGAGAGTCTGCTGGAAGAATTGTATGGC
CCGTTGCGCGACCAGCAACAGAAGGCAATCCGGGCCATTGAGGCGAGTGGACGGCATCTGCTGGCGCTGATTAATGATGT
CCTTGATCTGGCGAAGATTGAAGCCAACCGGATTGAACTGGTGAAAGAGGTAGTCGCCGCCAGCGATGTCTGTGAAGCAA
GTATGGCCCTCGTCAAAGAGCAGGCGACAAAGAAACAGATTCACCTTTCTATTCAGCTTGACGATCCCCATGCCCGGTTC
GTTGCCGATCCACGTCGCCTGAAGCAGATTCTGGTCAATTTGCTGAGTAATGCCGTGAAATTTACGCCGGCAGGTGGTGC
GGTGAGCTTGCAGGTGACAACAGATACTACGCAGGGAACGATTGCGTTCACGGTGAGCGATACCGGTATTGGGATTGCGG
AAGAGGATTTGTCGCGTCTGTTTCAGCCGTTTGTCCAGCTTGATAGCGGTTTGAGTCGGCAGCATGAAGGTACTGGGTTG
GGGTTAGTGCTGGTGCGTCGCCTTGTCGAACTGCACGGTGGCAAGGTGGAAGTTGAGAGTATGCCCGGTGTGGGTAGCAG
GTTTACGGTCACGCTGCCGTACCAGCCCGTGACGCACATCGCAGCATCCTCGTCTGCTGATGAACTTCCTCCGGTGCAAT
TAGCCCTGATCATCGAAGACTCGGCAACGACTGCCGATCAACTGGCCCGTTATCTCGAAGAATTGCAGATTCAACCTGTT
ATATGCTCGTATGGCAAAGGTGCGGTTGAGCAGGTACAGGCGTTACGTCCCGATCTGATTTTGCTCGATGTGCAGATGCC
AGATCGTTCAGGATGGGAGATACTGGCCGACCTGCGCCGCGACCCCGATCTGCGACAGGTTCCGGTGATCATTGTGTCGG
TAGTTGATGAACCAGAGCGTGGATTGGCTGCTGGAGCCGCAGCGTATCTGGTGAAGCCAATCAATCGACTTATGCTTCGG
CGTGCGCTAAGTCAGATTACTGTCACAAAAACGACATCCTCAACCGCTCCGCGGCGCCCGCTCAGCCGACGAATATTACT
GGCGGAAGATAATGAGGTCAATCGGGTCACCCTTAGCGATTACCTGGTTGCCCAGGGGTACGAGGTAAGAGTGGCGTGTC
AAGGGAAAGAAGCATTGCAGATTGCTGCTGAGTGGCGCCCTGATCTGATCATCATGGATATTCAAATGCCGGGACTCGAT
GGCCTGGAAGTGATACAACGGCTGCGTGCCGACGCGGCATTTGCTGCTACGCCTATCATTGCGGTGACGGCACTGGCGAT
GCCGGGTGATCGTGAACGGTGCCTGTCGGCTGGAGCAAATGACTATTTTGCGAAGCCGATCCGTCTGCGTCAATTGGTCG
AACGGATTGAGCAGTTTCTGGCGTCTTCACAACATGCCATATAA

Upstream 100 bases:

>100_bases
GTTGGCTGAGATGTCAACCACGCTAGCATAAACAGTTGCACCATGCTACGATACATGCTGGTAGGGTTTGTTGTTTCTCA
CGCTACCAGGATGGATACGC

Downstream 100 bases:

>100_bases
TTCCGTTCATGTTGGTACGCACGGTGTGCTACAATCTGACATCATACAGAGATCGGTGCTGTGCGCCAATCGCTGCCCCA
TGTCTCCACTGCCGTAGATC

Product: multi-sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1347; Mature: 1346

Protein sequence:

>1347_residues
MAQWSRRALISFGVVYAVLIWVGAQPLLANRGIPLLWVAGGFAAGGVLLAGKRLLPIIFIGAFIAYTVVFRQLGLSSERL
LAAALVFGLSAIIQAWLVNWLVRRFGRTLPPSSIRYTLVVCGLLALAVLPAPFLAVMVLVVVQQPLVSSPPIVALQWWLN
LVAGVWLVTPWMVLGEYYRQRRPMREPWLWPVSSLLLALMLFSLQLIWRDANRQFTTQLQADVNEVVSLINDRLTIYEQA
LLSQSALFLASQRVDQHEFSVFSRTQLARLPALRAVSWIPRIPLQQRTAFEHAMQETGLPDFRIREPDATARPADTRDEY
YPITYLEPFARRRAVLGLDLAADPVRRAAIEQARDSGQVVITAPLQSYLASDPAPAVLLFAPVYSGSLPPQSVEERRQRI
RGMVAFLIVPGEVIEQALRPVTTPDLEFVLVDATEESLRPLAVFTGGRAVPSPYISDLDIVIRDAVAISDIPRYGRVWSI
AFCLGTNYLPFWWSADAISRTVLAIASVAIFFLFVAIRQRHEARQRRLTRTYALLSAINQMIIRERDPQRIFQEVCQVGI
GEGGFRLVWIGRHNLVTSRFETIAIHSAKELDQSLVHLLTGEQLAMTLSPVCQGDRVVINDLATDPRCAAWRSQAVAYGL
RAMAGFPLVVPDEPPAVLCFYAGQPAAFDHDEIQLLDELVRDIIFGLLVSQQEAQLRTSEQRNHLIVSALPDLVLRLRPD
GQVVDVVAAESMVLPMAPTAMINSTLEQLFPAAIATQYRQALSAAFASGELQTLAYQLIVEAKEYFFEARIKAALPAEEA
IAIVRDVTAWRNAELALQVERDLLAQRVAERTAELHRANAELLRAARTKDEFLANMSHELRTPLNSILALSESLLEELYG
PLRDQQQKAIRAIEASGRHLLALINDVLDLAKIEANRIELVKEVVAASDVCEASMALVKEQATKKQIHLSIQLDDPHARF
VADPRRLKQILVNLLSNAVKFTPAGGAVSLQVTTDTTQGTIAFTVSDTGIGIAEEDLSRLFQPFVQLDSGLSRQHEGTGL
GLVLVRRLVELHGGKVEVESMPGVGSRFTVTLPYQPVTHIAASSSADELPPVQLALIIEDSATTADQLARYLEELQIQPV
ICSYGKGAVEQVQALRPDLILLDVQMPDRSGWEILADLRRDPDLRQVPVIIVSVVDEPERGLAAGAAAYLVKPINRLMLR
RALSQITVTKTTSSTAPRRPLSRRILLAEDNEVNRVTLSDYLVAQGYEVRVACQGKEALQIAAEWRPDLIIMDIQMPGLD
GLEVIQRLRADAAFAATPIIAVTALAMPGDRERCLSAGANDYFAKPIRLRQLVERIEQFLASSQHAI

Sequences:

>Translated_1347_residues
MAQWSRRALISFGVVYAVLIWVGAQPLLANRGIPLLWVAGGFAAGGVLLAGKRLLPIIFIGAFIAYTVVFRQLGLSSERL
LAAALVFGLSAIIQAWLVNWLVRRFGRTLPPSSIRYTLVVCGLLALAVLPAPFLAVMVLVVVQQPLVSSPPIVALQWWLN
LVAGVWLVTPWMVLGEYYRQRRPMREPWLWPVSSLLLALMLFSLQLIWRDANRQFTTQLQADVNEVVSLINDRLTIYEQA
LLSQSALFLASQRVDQHEFSVFSRTQLARLPALRAVSWIPRIPLQQRTAFEHAMQETGLPDFRIREPDATARPADTRDEY
YPITYLEPFARRRAVLGLDLAADPVRRAAIEQARDSGQVVITAPLQSYLASDPAPAVLLFAPVYSGSLPPQSVEERRQRI
RGMVAFLIVPGEVIEQALRPVTTPDLEFVLVDATEESLRPLAVFTGGRAVPSPYISDLDIVIRDAVAISDIPRYGRVWSI
AFCLGTNYLPFWWSADAISRTVLAIASVAIFFLFVAIRQRHEARQRRLTRTYALLSAINQMIIRERDPQRIFQEVCQVGI
GEGGFRLVWIGRHNLVTSRFETIAIHSAKELDQSLVHLLTGEQLAMTLSPVCQGDRVVINDLATDPRCAAWRSQAVAYGL
RAMAGFPLVVPDEPPAVLCFYAGQPAAFDHDEIQLLDELVRDIIFGLLVSQQEAQLRTSEQRNHLIVSALPDLVLRLRPD
GQVVDVVAAESMVLPMAPTAMINSTLEQLFPAAIATQYRQALSAAFASGELQTLAYQLIVEAKEYFFEARIKAALPAEEA
IAIVRDVTAWRNAELALQVERDLLAQRVAERTAELHRANAELLRAARTKDEFLANMSHELRTPLNSILALSESLLEELYG
PLRDQQQKAIRAIEASGRHLLALINDVLDLAKIEANRIELVKEVVAASDVCEASMALVKEQATKKQIHLSIQLDDPHARF
VADPRRLKQILVNLLSNAVKFTPAGGAVSLQVTTDTTQGTIAFTVSDTGIGIAEEDLSRLFQPFVQLDSGLSRQHEGTGL
GLVLVRRLVELHGGKVEVESMPGVGSRFTVTLPYQPVTHIAASSSADELPPVQLALIIEDSATTADQLARYLEELQIQPV
ICSYGKGAVEQVQALRPDLILLDVQMPDRSGWEILADLRRDPDLRQVPVIIVSVVDEPERGLAAGAAAYLVKPINRLMLR
RALSQITVTKTTSSTAPRRPLSRRILLAEDNEVNRVTLSDYLVAQGYEVRVACQGKEALQIAAEWRPDLIIMDIQMPGLD
GLEVIQRLRADAAFAATPIIAVTALAMPGDRERCLSAGANDYFAKPIRLRQLVERIEQFLASSQHAI
>Mature_1346_residues
AQWSRRALISFGVVYAVLIWVGAQPLLANRGIPLLWVAGGFAAGGVLLAGKRLLPIIFIGAFIAYTVVFRQLGLSSERLL
AAALVFGLSAIIQAWLVNWLVRRFGRTLPPSSIRYTLVVCGLLALAVLPAPFLAVMVLVVVQQPLVSSPPIVALQWWLNL
VAGVWLVTPWMVLGEYYRQRRPMREPWLWPVSSLLLALMLFSLQLIWRDANRQFTTQLQADVNEVVSLINDRLTIYEQAL
LSQSALFLASQRVDQHEFSVFSRTQLARLPALRAVSWIPRIPLQQRTAFEHAMQETGLPDFRIREPDATARPADTRDEYY
PITYLEPFARRRAVLGLDLAADPVRRAAIEQARDSGQVVITAPLQSYLASDPAPAVLLFAPVYSGSLPPQSVEERRQRIR
GMVAFLIVPGEVIEQALRPVTTPDLEFVLVDATEESLRPLAVFTGGRAVPSPYISDLDIVIRDAVAISDIPRYGRVWSIA
FCLGTNYLPFWWSADAISRTVLAIASVAIFFLFVAIRQRHEARQRRLTRTYALLSAINQMIIRERDPQRIFQEVCQVGIG
EGGFRLVWIGRHNLVTSRFETIAIHSAKELDQSLVHLLTGEQLAMTLSPVCQGDRVVINDLATDPRCAAWRSQAVAYGLR
AMAGFPLVVPDEPPAVLCFYAGQPAAFDHDEIQLLDELVRDIIFGLLVSQQEAQLRTSEQRNHLIVSALPDLVLRLRPDG
QVVDVVAAESMVLPMAPTAMINSTLEQLFPAAIATQYRQALSAAFASGELQTLAYQLIVEAKEYFFEARIKAALPAEEAI
AIVRDVTAWRNAELALQVERDLLAQRVAERTAELHRANAELLRAARTKDEFLANMSHELRTPLNSILALSESLLEELYGP
LRDQQQKAIRAIEASGRHLLALINDVLDLAKIEANRIELVKEVVAASDVCEASMALVKEQATKKQIHLSIQLDDPHARFV
ADPRRLKQILVNLLSNAVKFTPAGGAVSLQVTTDTTQGTIAFTVSDTGIGIAEEDLSRLFQPFVQLDSGLSRQHEGTGLG
LVLVRRLVELHGGKVEVESMPGVGSRFTVTLPYQPVTHIAASSSADELPPVQLALIIEDSATTADQLARYLEELQIQPVI
CSYGKGAVEQVQALRPDLILLDVQMPDRSGWEILADLRRDPDLRQVPVIIVSVVDEPERGLAAGAAAYLVKPINRLMLRR
ALSQITVTKTTSSTAPRRPLSRRILLAEDNEVNRVTLSDYLVAQGYEVRVACQGKEALQIAAEWRPDLIIMDIQMPGLDG
LEVIQRLRADAAFAATPIIAVTALAMPGDRERCLSAGANDYFAKPIRLRQLVERIEQFLASSQHAI

Specific function: Forms part of a two-component regulatory system gacA/gacS(lemA). May be involved in lesion formation, swarming and in the production of extracellular protease, syringomycin and N- acyl-L-homoserine lactone (acyl-HSL). Required for pathogenicity on bean [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=525, Percent_Identity=33.7142857142857, Blast_Score=219, Evalue=6e-58,
Organism=Escherichia coli, GI145693157, Length=533, Percent_Identity=30.0187617260788, Blast_Score=195, Evalue=2e-50,
Organism=Escherichia coli, GI1788713, Length=426, Percent_Identity=31.6901408450704, Blast_Score=176, Evalue=9e-45,
Organism=Escherichia coli, GI48994928, Length=371, Percent_Identity=34.2318059299191, Blast_Score=170, Evalue=6e-43,
Organism=Escherichia coli, GI87081816, Length=389, Percent_Identity=33.9331619537275, Blast_Score=158, Evalue=3e-39,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=33.1818181818182, Blast_Score=110, Evalue=5e-25,
Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=31.858407079646, Blast_Score=108, Evalue=3e-24,
Organism=Escherichia coli, GI1788393, Length=242, Percent_Identity=27.2727272727273, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1788549, Length=389, Percent_Identity=24.9357326478149, Blast_Score=98, Evalue=4e-21,
Organism=Escherichia coli, GI1790346, Length=232, Percent_Identity=29.3103448275862, Blast_Score=97, Evalue=6e-21,
Organism=Escherichia coli, GI1786783, Length=229, Percent_Identity=29.6943231441048, Blast_Score=95, Evalue=4e-20,
Organism=Escherichia coli, GI87082128, Length=231, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=9e-19,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=29.7413793103448, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1789808, Length=265, Percent_Identity=27.1698113207547, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1790861, Length=216, Percent_Identity=30.5555555555556, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI87082012, Length=124, Percent_Identity=36.2903225806452, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=36.697247706422, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788279, Length=241, Percent_Identity=25.3112033195021, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790863, Length=121, Percent_Identity=36.3636363636364, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1787894, Length=229, Percent_Identity=26.2008733624454, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1788394, Length=117, Percent_Identity=36.7521367521368, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789809, Length=117, Percent_Identity=35.042735042735, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1789403, Length=222, Percent_Identity=26.1261261261261, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1787375, Length=117, Percent_Identity=34.1880341880342, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=9e-12,
Organism=Escherichia coli, GI1787229, Length=116, Percent_Identity=35.3448275862069, Blast_Score=67, Evalue=9e-12,
Organism=Escherichia coli, GI1790300, Length=232, Percent_Identity=28.8793103448276, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786911, Length=112, Percent_Identity=35.7142857142857, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI1787487, Length=117, Percent_Identity=30.7692307692308, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=373, Percent_Identity=29.7587131367292, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 149126; Mature: 148995

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50839 CHASE ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQWSRRALISFGVVYAVLIWVGAQPLLANRGIPLLWVAGGFAAGGVLLAGKRLLPIIFI
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEECCHHHCCHHHCCCHHHHHHHH
GAFIAYTVVFRQLGLSSERLLAAALVFGLSAIIQAWLVNWLVRRFGRTLPPSSIRYTLVV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
CGLLALAVLPAPFLAVMVLVVVQQPLVSSPPIVALQWWLNLVAGVWLVTPWMVLGEYYRQ
HHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRPMREPWLWPVSSLLLALMLFSLQLIWRDANRQFTTQLQADVNEVVSLINDRLTIYEQA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSQSALFLASQRVDQHEFSVFSRTQLARLPALRAVSWIPRIPLQQRTAFEHAMQETGLP
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
DFRIREPDATARPADTRDEYYPITYLEPFARRRAVLGLDLAADPVRRAAIEQARDSGQVV
CCEEECCCCCCCCCCCCCCCCCCHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEE
ITAPLQSYLASDPAPAVLLFAPVYSGSLPPQSVEERRQRIRGMVAFLIVPGEVIEQALRP
EEECHHHHHCCCCCCEEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHEECCHHHHHHHHCC
VTTPDLEFVLVDATEESLRPLAVFTGGRAVPSPYISDLDIVIRDAVAISDIPRYGRVWSI
CCCCCCEEEEEECCHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHEE
AFCLGTNYLPFWWSADAISRTVLAIASVAIFFLFVAIRQRHEARQRRLTRTYALLSAINQ
HHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIIRERDPQRIFQEVCQVGIGEGGFRLVWIGRHNLVTSRFETIAIHSAKELDQSLVHLLT
HHHCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHEEHHHHHHHHHHHHHHC
GEQLAMTLSPVCQGDRVVINDLATDPRCAAWRSQAVAYGLRAMAGFPLVVPDEPPAVLCF
CCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEE
YAGQPAAFDHDEIQLLDELVRDIIFGLLVSQQEAQLRTSEQRNHLIVSALPDLVLRLRPD
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEHHHHHHHHEEECCC
GQVVDVVAAESMVLPMAPTAMINSTLEQLFPAAIATQYRQALSAAFASGELQTLAYQLIV
CCEEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
EAKEYFFEARIKAALPAEEAIAIVRDVTAWRNAELALQVERDLLAQRVAERTAELHRANA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
ELLRAARTKDEFLANMSHELRTPLNSILALSESLLEELYGPLRDQQQKAIRAIEASGRHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHH
LALINDVLDLAKIEANRIELVKEVVAASDVCEASMALVKEQATKKQIHLSIQLDDPHARF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCHHH
VADPRRLKQILVNLLSNAVKFTPAGGAVSLQVTTDTTQGTIAFTVSDTGIGIAEEDLSRL
CCCHHHHHHHHHHHHHHHEEECCCCCEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHH
FQPFVQLDSGLSRQHEGTGLGLVLVRRLVELHGGKVEVESMPGVGSRFTVTLPYQPVTHI
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCHHHHH
AASSSADELPPVQLALIIEDSATTADQLARYLEELQIQPVICSYGKGAVEQVQALRPDLI
HCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCEECCCCCHHHHHHHCCCCEE
LLDVQMPDRSGWEILADLRRDPDLRQVPVIIVSVVDEPERGLAAGAAAYLVKPINRLMLR
EEEEECCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
RALSQITVTKTTSSTAPRRPLSRRILLAEDNEVNRVTLSDYLVAQGYEVRVACQGKEALQ
HHHHHEEEEECCCCCCCCCCCCCEEEEECCCCCCEEEHHHHHHHCCCEEEEEECCHHHHH
IAAEWRPDLIIMDIQMPGLDGLEVIQRLRADAAFAATPIIAVTALAMPGDRERCLSAGAN
HHHCCCCCEEEEEEECCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHCCCC
DYFAKPIRLRQLVERIEQFLASSQHAI
CHHCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AQWSRRALISFGVVYAVLIWVGAQPLLANRGIPLLWVAGGFAAGGVLLAGKRLLPIIFI
CCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEECCHHHCCHHHCCCHHHHHHHH
GAFIAYTVVFRQLGLSSERLLAAALVFGLSAIIQAWLVNWLVRRFGRTLPPSSIRYTLVV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
CGLLALAVLPAPFLAVMVLVVVQQPLVSSPPIVALQWWLNLVAGVWLVTPWMVLGEYYRQ
HHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRPMREPWLWPVSSLLLALMLFSLQLIWRDANRQFTTQLQADVNEVVSLINDRLTIYEQA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSQSALFLASQRVDQHEFSVFSRTQLARLPALRAVSWIPRIPLQQRTAFEHAMQETGLP
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
DFRIREPDATARPADTRDEYYPITYLEPFARRRAVLGLDLAADPVRRAAIEQARDSGQVV
CCEEECCCCCCCCCCCCCCCCCCHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEE
ITAPLQSYLASDPAPAVLLFAPVYSGSLPPQSVEERRQRIRGMVAFLIVPGEVIEQALRP
EEECHHHHHCCCCCCEEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHEECCHHHHHHHHCC
VTTPDLEFVLVDATEESLRPLAVFTGGRAVPSPYISDLDIVIRDAVAISDIPRYGRVWSI
CCCCCCEEEEEECCHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHEE
AFCLGTNYLPFWWSADAISRTVLAIASVAIFFLFVAIRQRHEARQRRLTRTYALLSAINQ
HHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIIRERDPQRIFQEVCQVGIGEGGFRLVWIGRHNLVTSRFETIAIHSAKELDQSLVHLLT
HHHCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHEEHHHHHHHHHHHHHHC
GEQLAMTLSPVCQGDRVVINDLATDPRCAAWRSQAVAYGLRAMAGFPLVVPDEPPAVLCF
CCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEE
YAGQPAAFDHDEIQLLDELVRDIIFGLLVSQQEAQLRTSEQRNHLIVSALPDLVLRLRPD
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEHHHHHHHHEEECCC
GQVVDVVAAESMVLPMAPTAMINSTLEQLFPAAIATQYRQALSAAFASGELQTLAYQLIV
CCEEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
EAKEYFFEARIKAALPAEEAIAIVRDVTAWRNAELALQVERDLLAQRVAERTAELHRANA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
ELLRAARTKDEFLANMSHELRTPLNSILALSESLLEELYGPLRDQQQKAIRAIEASGRHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHH
LALINDVLDLAKIEANRIELVKEVVAASDVCEASMALVKEQATKKQIHLSIQLDDPHARF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCHHH
VADPRRLKQILVNLLSNAVKFTPAGGAVSLQVTTDTTQGTIAFTVSDTGIGIAEEDLSRL
CCCHHHHHHHHHHHHHHHEEECCCCCEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHH
FQPFVQLDSGLSRQHEGTGLGLVLVRRLVELHGGKVEVESMPGVGSRFTVTLPYQPVTHI
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCHHHHH
AASSSADELPPVQLALIIEDSATTADQLARYLEELQIQPVICSYGKGAVEQVQALRPDLI
HCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCEECCCCCHHHHHHHCCCCEE
LLDVQMPDRSGWEILADLRRDPDLRQVPVIIVSVVDEPERGLAAGAAAYLVKPINRLMLR
EEEEECCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
RALSQITVTKTTSSTAPRRPLSRRILLAEDNEVNRVTLSDYLVAQGYEVRVACQGKEALQ
HHHHHEEEEECCCCCCCCCCCCCEEEEECCCCCCEEEHHHHHHHCCCEEEEEECCHHHHH
IAAEWRPDLIIMDIQMPGLDGLEVIQRLRADAAFAATPIIAVTALAMPGDRERCLSAGAN
HHHCCCCCEEEEEEECCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHCCCC
DYFAKPIRLRQLVERIEQFLASSQHAI
CHHCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1314807 [H]