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The map label for this gene is moaB [H]

Identifier: 222523716

GI number: 222523716

Start: 502156

End: 502665

Strand: Direct

Name: moaB [H]

Synonym: Chy400_0422

Alternate gene names: 222523716

Gene position: 502156-502665 (Clockwise)

Preceding gene: 222523713

Following gene: 222523717

Centisome position: 9.53

GC content: 56.67

Gene sequence:

>510_bases
ATGAGCCACCAGGAACACCGCCGCCTGGCGGAAACACAGACGACGGCTATTCCCTGTGCCGTACTGACCATCAGCGACAG
TCGCAGTGAAGCGACCGACGATAGCGGGCGATATATCTGCACTGCGTTGACGCAAGCCGGCCACAATGTGGTACAATATG
CCGTGGTGCGAGATGAGCCGGCGCAAATTGTGGAAATGGTGCGTCGTTTTGCCGCCGAAGGATGTAAAGTCATCATCACG
AATGGCGGCACCGGTATCTCCCGCCGGGACAGCACCTTTGAAGCGATTGATGCCTTGCTCGAAAAACGATTACCGGGTTT
CGGCGAACTTTTTCGCATGCTCTCATTCGCCGAGATTGGGCCGGCGGCAATGCTGTCACGAGCGACAGCCGGTGTTTTTG
GCGGAACATTAATCTTTTGCCTGCCAGGTTCGCCCAACGCCGTTCAGCTTGGTATCGACCGCCTCATCTTGCCCGAACTG
GCGCATCTGGTTTGGGAAACTGTGCGCTAA

Upstream 100 bases:

>100_bases
ATACCACCGGTATCGCGACACACATCAACATACCATTGGACACATTGCCCCAAAATGTGGTAGGATACAGCAGGTGAAAC
AATGGTAAGGATATCGTTGT

Downstream 100 bases:

>100_bases
TTGCTATTTTCTGTTATAGTATGTGTGTTGTCGTAAAGAGTTGTTCTCTTCGTAGCTGTGAGAAGGAGCCAGAGAACCCA
TGACGTCAGTAGAAGCCTTC

Product: molybdenum cofactor synthesis domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MSHQEHRRLAETQTTAIPCAVLTISDSRSEATDDSGRYICTALTQAGHNVVQYAVVRDEPAQIVEMVRRFAAEGCKVIIT
NGGTGISRRDSTFEAIDALLEKRLPGFGELFRMLSFAEIGPAAMLSRATAGVFGGTLIFCLPGSPNAVQLGIDRLILPEL
AHLVWETVR

Sequences:

>Translated_169_residues
MSHQEHRRLAETQTTAIPCAVLTISDSRSEATDDSGRYICTALTQAGHNVVQYAVVRDEPAQIVEMVRRFAAEGCKVIIT
NGGTGISRRDSTFEAIDALLEKRLPGFGELFRMLSFAEIGPAAMLSRATAGVFGGTLIFCLPGSPNAVQLGIDRLILPEL
AHLVWETVR
>Mature_168_residues
SHQEHRRLAETQTTAIPCAVLTISDSRSEATDDSGRYICTALTQAGHNVVQYAVVRDEPAQIVEMVRRFAAEGCKVIITN
GGTGISRRDSTFEAIDALLEKRLPGFGELFRMLSFAEIGPAAMLSRATAGVFGGTLIFCLPGSPNAVQLGIDRLILPELA
HLVWETVR

Specific function: Maybe involved in the biosynthesis of molybdopterin [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=154, Percent_Identity=35.7142857142857, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI10880983, Length=154, Percent_Identity=35.7142857142857, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1787000, Length=155, Percent_Identity=40, Blast_Score=115, Evalue=1e-27,
Organism=Escherichia coli, GI1786190, Length=136, Percent_Identity=32.3529411764706, Blast_Score=64, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17136978, Length=159, Percent_Identity=35.8490566037736, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24638841, Length=159, Percent_Identity=35.8490566037736, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18328; Mature: 18197

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHQEHRRLAETQTTAIPCAVLTISDSRSEATDDSGRYICTALTQAGHNVVQYAVVRDEP
CCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEEHHHHCCCHHEEEEEECCCH
AQIVEMVRRFAAEGCKVIITNGGTGISRRDSTFEAIDALLEKRLPGFGELFRMLSFAEIG
HHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
PAAMLSRATAGVFGGTLIFCLPGSPNAVQLGIDRLILPELAHLVWETVR
HHHHHHHHHHHHCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SHQEHRRLAETQTTAIPCAVLTISDSRSEATDDSGRYICTALTQAGHNVVQYAVVRDEP
CCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEEHHHHCCCHHEEEEEECCCH
AQIVEMVRRFAAEGCKVIITNGGTGISRRDSTFEAIDALLEKRLPGFGELFRMLSFAEIG
HHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
PAAMLSRATAGVFGGTLIFCLPGSPNAVQLGIDRLILPELAHLVWETVR
HHHHHHHHHHHHCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]