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The map label for this gene is infC [H]

Identifier: 222523703

GI number: 222523703

Start: 484177

End: 485004

Strand: Direct

Name: infC [H]

Synonym: Chy400_0409

Alternate gene names: 222523703

Gene position: 484177-485004 (Clockwise)

Preceding gene: 222523698

Following gene: 222523704

Centisome position: 9.19

GC content: 53.74

Gene sequence:

>828_bases
TTGCCACGACTGTCACCTGTTGCAAGACGAAGGAGTCGTGCCATTAGAGACCGGTTTCGCATCAACAATCGCATTCGCGC
CCGTGAAGTGCGTCTCATCGACGAGAACGGCACCCAGGTTGGCATTGTTCCCCTGCGTGAGGCGCTGGCAATGGCTGAAG
AACGAGGGTTTGATCTCGTCGAAGTTGCGCCTAATGCGGTTCCACCGGTATGCCGTCTGCTCGATTATGGCAAATTCCGC
TACGAGCAGAGCAAAAAAGAGCGTGAAGCACGCCGTAATCAGAAACAGTCGGAACTGAAGCAGATTCGACTGATGCCGAA
AACTGATGACCACGACGTCGCAGTGAAGGCAAATCAAGCACGACGTTTCTTACTGGCGGGCGATAAGGTTAAGTTTAATC
TGCGCTTCCGTGGTCGCGAAATGGCTCATCCCGAAATCGGGCGTCAAATGCTCGATCAAATCGCCGAGCAATTGAGCGAT
ATTGCTGTCATCGAGCAGAAACCGCTCATGGAAGGACGGGTTTTGTCAATGCTGCTTGCCCCAACCGCCAAGGTGTTGAA
GGCAGCACAACAGGCCCAAAAGGCAGCAGCTCAGCGCACAACAACCGCCGAGTCAGCAAAGCCAGCGACAAGTGCGGCAT
CTACTCCTGCTACGGCAGAACCGGCAGATGAAGAAGAGGAAGAGCTGATTGATGATGGCGATGTCGTCGAAGAAGATGAG
GACGACGACGACACCTTCGTTGCAGATTACGACGACGAAGACGACGATTTTGAAGATGACGATGATGATGACGAGGACGA
CGAGCGAAATCGCCGGAGACGACGCTAA

Upstream 100 bases:

>100_bases
ACTGACTGGTATAATGCCCAATTGACCAGACATCGCTGTAGAGCGGTGTCATCTTATTGTTGCAGTTAGCCGTAAGGGTG
ACAACAGGTCGTCTTCATCT

Downstream 100 bases:

>100_bases
GTGATACGATGCCGGACGGCTAGCCGCTGTTCAGTGGCACTAGAGGAGATTGTCGATGCCTAAGATGAAAATGAAGACGC
ACAAGGGCGCGAAAAAGCGC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MPRLSPVARRRSRAIRDRFRINNRIRAREVRLIDENGTQVGIVPLREALAMAEERGFDLVEVAPNAVPPVCRLLDYGKFR
YEQSKKEREARRNQKQSELKQIRLMPKTDDHDVAVKANQARRFLLAGDKVKFNLRFRGREMAHPEIGRQMLDQIAEQLSD
IAVIEQKPLMEGRVLSMLLAPTAKVLKAAQQAQKAAAQRTTTAESAKPATSAASTPATAEPADEEEEELIDDGDVVEEDE
DDDDTFVADYDDEDDDFEDDDDDDEDDERNRRRRR

Sequences:

>Translated_275_residues
MPRLSPVARRRSRAIRDRFRINNRIRAREVRLIDENGTQVGIVPLREALAMAEERGFDLVEVAPNAVPPVCRLLDYGKFR
YEQSKKEREARRNQKQSELKQIRLMPKTDDHDVAVKANQARRFLLAGDKVKFNLRFRGREMAHPEIGRQMLDQIAEQLSD
IAVIEQKPLMEGRVLSMLLAPTAKVLKAAQQAQKAAAQRTTTAESAKPATSAASTPATAEPADEEEEELIDDGDVVEEDE
DDDDTFVADYDDEDDDFEDDDDDDEDDERNRRRRR
>Mature_274_residues
PRLSPVARRRSRAIRDRFRINNRIRAREVRLIDENGTQVGIVPLREALAMAEERGFDLVEVAPNAVPPVCRLLDYGKFRY
EQSKKEREARRNQKQSELKQIRLMPKTDDHDVAVKANQARRFLLAGDKVKFNLRFRGREMAHPEIGRQMLDQIAEQLSDI
AVIEQKPLMEGRVLSMLLAPTAKVLKAAQQAQKAAAQRTTTAESAKPATSAASTPATAEPADEEEEELIDDGDVVEEDED
DDDTFVADYDDEDDDFEDDDDDDEDDERNRRRRR

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=166, Percent_Identity=53.6144578313253, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 31444; Mature: 31313

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLSPVARRRSRAIRDRFRINNRIRAREVRLIDENGTQVGIVPLREALAMAEERGFDLV
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEHHHHHHHHHHHHHCCCCEE
EVAPNAVPPVCRLLDYGKFRYEQSKKEREARRNQKQSELKQIRLMPKTDDHDVAVKANQA
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCC
RRFLLAGDKVKFNLRFRGREMAHPEIGRQMLDQIAEQLSDIAVIEQKPLMEGRVLSMLLA
CEEEEECCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
PTAKVLKAAQQAQKAAAQRTTTAESAKPATSAASTPATAEPADEEEEELIDDGDVVEEDE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCC
DDDDTFVADYDDEDDDFEDDDDDDEDDERNRRRRR
CCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
PRLSPVARRRSRAIRDRFRINNRIRAREVRLIDENGTQVGIVPLREALAMAEERGFDLV
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEHHHHHHHHHHHHHCCCCEE
EVAPNAVPPVCRLLDYGKFRYEQSKKEREARRNQKQSELKQIRLMPKTDDHDVAVKANQA
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCC
RRFLLAGDKVKFNLRFRGREMAHPEIGRQMLDQIAEQLSDIAVIEQKPLMEGRVLSMLLA
CEEEEECCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
PTAKVLKAAQQAQKAAAQRTTTAESAKPATSAASTPATAEPADEEEEELIDDGDVVEEDE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCC
DDDDTFVADYDDEDDDFEDDDDDDEDDERNRRRRR
CCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA