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The map label for this gene is 222523663

Identifier: 222523663

GI number: 222523663

Start: 436260

End: 437318

Strand: Direct

Name: 222523663

Synonym: Chy400_0369

Alternate gene names: NA

Gene position: 436260-437318 (Clockwise)

Preceding gene: 222523661

Following gene: 222523664

Centisome position: 8.28

GC content: 58.73

Gene sequence:

>1059_bases
ATGACCACTGCAATTGTGACCGATCAGCGGTTTGATCTTCACACATGGCACGGGCACGTTGAGCAGGCCGAGCGGTTGCA
CGCCATCCGACGGGCAATTGAGGTCGATGGGTTGTGGCCGCGTTTGCTTCAGTTACCCATTCGTCCGGCCACTGAAGCTG
AATTGCTTGCTGTCCATAGCTCCAGCATGCTTCATCGCGTGCGTCAGTTAGCCAGTTATGGCGGTGGACAGATCGATAGC
GACACCTACGTCACTGCCGAGTCGTGGGATGTTGCGCTGCTGGCAGCAGGCGCAACGATTTGTATGGCTGAAGCCCTGGT
AAGCGGACGCTGCCACAATGCGTTTGCGCTGGTGCGGCCACCGGGCCACCATGCGACCGATATACGCTCGATGGGTTTCT
GCCTCTTCAATAATATTGCAGTCGCTGCACGAGTGTTGCTGGATCGCCACCATCTCCGGCGCATCGCGATTGTGGATTTC
GATGTTCATCACGGTAATGGCACTCAGGACATCTTCTACCGTGATGGGCGAGTTCTCTTTTGCTCGATCCATGCCGCGCC
GCTCTACCCAGGCACCGGCAGTCTTCACGAAATGGGTGATCCGCGCACAGCCGGCGGCACCACCCTCAACGTACCGTTGC
CCTATGGAACCGGCGATCACGGCTACGAACAGGTATTTCAGCGCGTCATCGGGCCAGTGCTCCGCCGTTTTCAACCGGAG
ATCATTCTGGTGTCAGCCGGCTTTGATGCCCACTGGAGTGATCCGATTGGGCCGATGGCGCTCTCGATCCAGGGCTTTGC
CCGCATCGTGCAGCACCTGTGCGATTGGGCTGACGAGTTGTGTGACGGTCGGATCGGCTTCGTACTGGAAGGCGGGTATA
GCCTGCCGGCGCTGGCGGCGGGTGTAGTGACGACGCTCCGCCTGCTGTTGGGGATGCCGGCCGGTTCTGACCCCATGGGC
AAGATGAATGCACCCGAACCGGCCATCGAACACATCATCACCAGTCTCTACACCTACCATCCTCTGCTGATGCAGACAAC
ATATCAGGGAGAAGCATGA

Upstream 100 bases:

>100_bases
CGACACACGCTTCCCGCCATCCGCCGGCCTCGTGGTACAATGAATGCAATTGTCGTAGCGAGAGTATCCGGCTGCGCTCC
AGGGCGGTACAGGCACAGAT

Downstream 100 bases:

>100_bases
TAGCAGTGATTAACTACGGTGCCGGCAACCTGCCCAATGTGGTACGGGCACTACAACGGGTCGGCGCTACACTCACCGTA
ACCGATAACCCAGAGGTGAT

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTTAIVTDQRFDLHTWHGHVEQAERLHAIRRAIEVDGLWPRLLQLPIRPATEAELLAVHSSSMLHRVRQLASYGGGQIDS
DTYVTAESWDVALLAAGATICMAEALVSGRCHNAFALVRPPGHHATDIRSMGFCLFNNIAVAARVLLDRHHLRRIAIVDF
DVHHGNGTQDIFYRDGRVLFCSIHAAPLYPGTGSLHEMGDPRTAGGTTLNVPLPYGTGDHGYEQVFQRVIGPVLRRFQPE
IILVSAGFDAHWSDPIGPMALSIQGFARIVQHLCDWADELCDGRIGFVLEGGYSLPALAAGVVTTLRLLLGMPAGSDPMG
KMNAPEPAIEHIITSLYTYHPLLMQTTYQGEA

Sequences:

>Translated_352_residues
MTTAIVTDQRFDLHTWHGHVEQAERLHAIRRAIEVDGLWPRLLQLPIRPATEAELLAVHSSSMLHRVRQLASYGGGQIDS
DTYVTAESWDVALLAAGATICMAEALVSGRCHNAFALVRPPGHHATDIRSMGFCLFNNIAVAARVLLDRHHLRRIAIVDF
DVHHGNGTQDIFYRDGRVLFCSIHAAPLYPGTGSLHEMGDPRTAGGTTLNVPLPYGTGDHGYEQVFQRVIGPVLRRFQPE
IILVSAGFDAHWSDPIGPMALSIQGFARIVQHLCDWADELCDGRIGFVLEGGYSLPALAAGVVTTLRLLLGMPAGSDPMG
KMNAPEPAIEHIITSLYTYHPLLMQTTYQGEA
>Mature_351_residues
TTAIVTDQRFDLHTWHGHVEQAERLHAIRRAIEVDGLWPRLLQLPIRPATEAELLAVHSSSMLHRVRQLASYGGGQIDSD
TYVTAESWDVALLAAGATICMAEALVSGRCHNAFALVRPPGHHATDIRSMGFCLFNNIAVAARVLLDRHHLRRIAIVDFD
VHHGNGTQDIFYRDGRVLFCSIHAAPLYPGTGSLHEMGDPRTAGGTTLNVPLPYGTGDHGYEQVFQRVIGPVLRRFQPEI
ILVSAGFDAHWSDPIGPMALSIQGFARIVQHLCDWADELCDGRIGFVLEGGYSLPALAAGVVTTLRLLLGMPAGSDPMGK
MNAPEPAIEHIITSLYTYHPLLMQTTYQGEA

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128864, Length=343, Percent_Identity=36.1516034985423, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI20070354, Length=336, Percent_Identity=37.797619047619, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI17158039, Length=328, Percent_Identity=33.8414634146341, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI30795202, Length=328, Percent_Identity=33.8414634146341, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI30795204, Length=328, Percent_Identity=33.8414634146341, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI153085395, Length=350, Percent_Identity=35.1428571428571, Blast_Score=164, Evalue=8e-41,
Organism=Homo sapiens, GI148539870, Length=328, Percent_Identity=34.7560975609756, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI169234807, Length=328, Percent_Identity=34.7560975609756, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI62750349, Length=351, Percent_Identity=32.7635327635328, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI62750347, Length=351, Percent_Identity=32.7635327635328, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI226529806, Length=336, Percent_Identity=34.5238095238095, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI13128862, Length=274, Percent_Identity=27.7372262773723, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI13128860, Length=266, Percent_Identity=27.0676691729323, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI8923769, Length=304, Percent_Identity=25.3289473684211, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI293336691, Length=266, Percent_Identity=26.6917293233083, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI262073092, Length=219, Percent_Identity=26.9406392694064, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI262073088, Length=182, Percent_Identity=25.8241758241758, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI209862883, Length=227, Percent_Identity=25.5506607929515, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI217272877, Length=147, Percent_Identity=29.2517006802721, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17540334, Length=318, Percent_Identity=34.9056603773585, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17540332, Length=321, Percent_Identity=34.5794392523364, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI193206283, Length=321, Percent_Identity=34.5794392523364, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI193209491, Length=347, Percent_Identity=35.4466858789625, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17537347, Length=321, Percent_Identity=36.4485981308411, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI25154020, Length=301, Percent_Identity=31.2292358803987, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI25154022, Length=301, Percent_Identity=30.8970099667774, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17508561, Length=276, Percent_Identity=29.3478260869565, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17534739, Length=245, Percent_Identity=32.2448979591837, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17561978, Length=262, Percent_Identity=27.8625954198473, Blast_Score=100, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6324307, Length=328, Percent_Identity=34.4512195121951, Blast_Score=189, Evalue=7e-49,
Organism=Saccharomyces cerevisiae, GI6323999, Length=271, Percent_Identity=29.8892988929889, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6321244, Length=237, Percent_Identity=29.957805907173, Blast_Score=102, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6325325, Length=150, Percent_Identity=32, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6325141, Length=363, Percent_Identity=22.5895316804408, Blast_Score=73, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24642146, Length=329, Percent_Identity=37.6899696048632, Blast_Score=198, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24642142, Length=329, Percent_Identity=37.6899696048632, Blast_Score=198, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24642144, Length=329, Percent_Identity=37.6899696048632, Blast_Score=198, Evalue=4e-51,
Organism=Drosophila melanogaster, GI281360899, Length=329, Percent_Identity=37.9939209726444, Blast_Score=198, Evalue=5e-51,
Organism=Drosophila melanogaster, GI281360801, Length=350, Percent_Identity=35.7142857142857, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24641720, Length=350, Percent_Identity=35.7142857142857, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI281360799, Length=350, Percent_Identity=35.7142857142857, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24644244, Length=279, Percent_Identity=27.5985663082437, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24657891, Length=273, Percent_Identity=26.7399267399267, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286
- InterPro:   IPR003084 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 38528; Mature: 38396

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAIVTDQRFDLHTWHGHVEQAERLHAIRRAIEVDGLWPRLLQLPIRPATEAELLAVHS
CCCEEEECCCCEEEHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHEEHHH
SSMLHRVRQLASYGGGQIDSDTYVTAESWDVALLAAGATICMAEALVSGRCHNAFALVRP
HHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEECCCHHHHHHHHHHCCCCCCEEEEECC
PGHHATDIRSMGFCLFNNIAVAARVLLDRHHLRRIAIVDFDVHHGNGTQDIFYRDGRVLF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCCCEEEEECCEEEE
CSIHAAPLYPGTGSLHEMGDPRTAGGTTLNVPLPYGTGDHGYEQVFQRVIGPVLRRFQPE
EEEECCCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCC
IILVSAGFDAHWSDPIGPMALSIQGFARIVQHLCDWADELCDGRIGFVLEGGYSLPALAA
EEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHH
GVVTTLRLLLGMPAGSDPMGKMNAPEPAIEHIITSLYTYHPLLMQTTYQGEA
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHEEECCCCCC
>Mature Secondary Structure 
TTAIVTDQRFDLHTWHGHVEQAERLHAIRRAIEVDGLWPRLLQLPIRPATEAELLAVHS
CCEEEECCCCEEEHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHEEHHH
SSMLHRVRQLASYGGGQIDSDTYVTAESWDVALLAAGATICMAEALVSGRCHNAFALVRP
HHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEECCCHHHHHHHHHHCCCCCCEEEEECC
PGHHATDIRSMGFCLFNNIAVAARVLLDRHHLRRIAIVDFDVHHGNGTQDIFYRDGRVLF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCCCEEEEECCEEEE
CSIHAAPLYPGTGSLHEMGDPRTAGGTTLNVPLPYGTGDHGYEQVFQRVIGPVLRRFQPE
EEEECCCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCC
IILVSAGFDAHWSDPIGPMALSIQGFARIVQHLCDWADELCDGRIGFVLEGGYSLPALAA
EEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHH
GVVTTLRLLLGMPAGSDPMGKMNAPEPAIEHIITSLYTYHPLLMQTTYQGEA
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]