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The map label for this gene is steT [H]

Identifier: 222152082

GI number: 222152082

Start: 1974067

End: 1975419

Strand: Direct

Name: steT [H]

Synonym: MCCL_1839

Alternate gene names: 222152082

Gene position: 1974067-1975419 (Clockwise)

Preceding gene: 222152077

Following gene: 222152087

Centisome position: 93.9

GC content: 38.06

Gene sequence:

>1353_bases
ATGAATAAACATCATGGAGAACAAGCGCTCGAAAAAACGATAGGATTCTGGACTGCAATCACGGTAGTTATCGGAACCAT
CATTGGTTCAGGCGTATTCGTTAAACCTTCTGTGGTGCTCAATCATGCAGGTACAAGCGATCTTGCAATTTGGGCCTGGG
TTGTCGGGGGTATATTAACATTAGCAGCAGGTCTGACTATTGCAGAAGTAGGCGCACAAATACCAAAAACCGGCGGACTA
TATGCTTATATTAGAGATATTTATGGTCCGTTCTGGGGATTTTTAACAGGTTGGATGCAGACAGTCATCTATGGCCCCGC
AATTATTGCTTCACTTTCATTATTCTTCGGTATACTCGTAACGAACTTTTTTGGAATCGATCCAGACTTAGGTATATGGA
TCGGCATCGCAGCATTTACTTTTCTTGTCATTCTTAATATTCTTGGTACAAATGCTGGCGGCGCGATGCAGACCTTCACT
ACAATCTGTAAACTGATTCCTGTATTTGCGATTATTATCTTCGGTTTATTGTGGGGTAAAGAAGGTGTATTCGGTCATAA
CGTGACAAGCTTGATTGAAAATAAAGGAGAAGTTAATTTCGGTCGTGCCGTTCTTGCTACGTTATTTGCATACGATGGAT
GGATTTTGCTGACAAATTTAACAGGCGAAATGAAGAATGCAAAACGTAACCTGCCACTTGCGATGCTTGTAGGATTAAGC
GTTGTTACATTTGCATATGTACTCATTAATATTGCTGTCTTTAAAGTTATTCCTGCTGAAACGCTTGTTGGCCTTGGAAA
CACTTCTTCTGCCGAAGCGGCTAAAATATTATTCGGCGATCTCGGTTCTAAATTTGTTAATATTGGTGTCATTATTTCAA
TATTTGGTTGCTTGAACGGGAAAATCATGACTTTCCCTCGTATACCATTTGCGATGGCAGATGATAATTTATTACCGTTT
GCGAAATTTATCAGCTATGTAAGTCCTAAATTTAAAACACCAATTGGTGCAATGATCACAATGTATGTTGTAAGTATGAT
TCTACTTCTACTTACGATTGTAATTCCTGAAATCGTCAATGCAGACTACTTATCTGAAATATGTATATTCGTAATTTATA
TCTTCTATATCGCCAGTTTTATCGGATTGTTTATATTACGTAAACAAACTAAAGGACAAAAACGTGACTATTCAGTACCA
CTATATCCAATCGTCCCTATCATTGCGATGGGTGGTGGCCTATTCATTATTATTAGCACATTAATGAGTGATTTCTTCGG
TTCGATGCTCGGTGTACTTTTTGTAGTTATCGGAATTCCATTTTATTTCATGTTGCACAAAAAACATGTTTAA

Upstream 100 bases:

>100_bases
TAAATCAACAAGTATTTATAAGAAATACTTTATTGAATTACTATTCTTTATATTCAGATTTCATGATATATTGATAAAAA
CAATAAAAAGAGGTGGCGTT

Downstream 100 bases:

>100_bases
TATTGGTAATAACGGTTATATAACAATTAATAAATTATAGAAATGAGGCTATACTATGAAACGTTTAGTTCAACTAATCA
TTAAATTAAGTCCTATCTTA

Product: amino acid/polyamine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MNKHHGEQALEKTIGFWTAITVVIGTIIGSGVFVKPSVVLNHAGTSDLAIWAWVVGGILTLAAGLTIAEVGAQIPKTGGL
YAYIRDIYGPFWGFLTGWMQTVIYGPAIIASLSLFFGILVTNFFGIDPDLGIWIGIAAFTFLVILNILGTNAGGAMQTFT
TICKLIPVFAIIIFGLLWGKEGVFGHNVTSLIENKGEVNFGRAVLATLFAYDGWILLTNLTGEMKNAKRNLPLAMLVGLS
VVTFAYVLINIAVFKVIPAETLVGLGNTSSAEAAKILFGDLGSKFVNIGVIISIFGCLNGKIMTFPRIPFAMADDNLLPF
AKFISYVSPKFKTPIGAMITMYVVSMILLLLTIVIPEIVNADYLSEICIFVIYIFYIASFIGLFILRKQTKGQKRDYSVP
LYPIVPIIAMGGGLFIIISTLMSDFFGSMLGVLFVVIGIPFYFMLHKKHV

Sequences:

>Translated_450_residues
MNKHHGEQALEKTIGFWTAITVVIGTIIGSGVFVKPSVVLNHAGTSDLAIWAWVVGGILTLAAGLTIAEVGAQIPKTGGL
YAYIRDIYGPFWGFLTGWMQTVIYGPAIIASLSLFFGILVTNFFGIDPDLGIWIGIAAFTFLVILNILGTNAGGAMQTFT
TICKLIPVFAIIIFGLLWGKEGVFGHNVTSLIENKGEVNFGRAVLATLFAYDGWILLTNLTGEMKNAKRNLPLAMLVGLS
VVTFAYVLINIAVFKVIPAETLVGLGNTSSAEAAKILFGDLGSKFVNIGVIISIFGCLNGKIMTFPRIPFAMADDNLLPF
AKFISYVSPKFKTPIGAMITMYVVSMILLLLTIVIPEIVNADYLSEICIFVIYIFYIASFIGLFILRKQTKGQKRDYSVP
LYPIVPIIAMGGGLFIIISTLMSDFFGSMLGVLFVVIGIPFYFMLHKKHV
>Mature_450_residues
MNKHHGEQALEKTIGFWTAITVVIGTIIGSGVFVKPSVVLNHAGTSDLAIWAWVVGGILTLAAGLTIAEVGAQIPKTGGL
YAYIRDIYGPFWGFLTGWMQTVIYGPAIIASLSLFFGILVTNFFGIDPDLGIWIGIAAFTFLVILNILGTNAGGAMQTFT
TICKLIPVFAIIIFGLLWGKEGVFGHNVTSLIENKGEVNFGRAVLATLFAYDGWILLTNLTGEMKNAKRNLPLAMLVGLS
VVTFAYVLINIAVFKVIPAETLVGLGNTSSAEAAKILFGDLGSKFVNIGVIISIFGCLNGKIMTFPRIPFAMADDNLLPF
AKFISYVSPKFKTPIGAMITMYVVSMILLLLTIVIPEIVNADYLSEICIFVIYIFYIASFIGLFILRKQTKGQKRDYSVP
LYPIVPIIAMGGGLFIIISTLMSDFFGSMLGVLFVVIGIPFYFMLHKKHV

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI187423910, Length=463, Percent_Identity=30.0215982721382, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI7657591, Length=463, Percent_Identity=30.0215982721382, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI115648063, Length=452, Percent_Identity=28.9823008849558, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI115648022, Length=452, Percent_Identity=28.9823008849558, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI7657683, Length=417, Percent_Identity=29.9760191846523, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI33286428, Length=448, Percent_Identity=31.25, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI186910308, Length=460, Percent_Identity=27.1739130434783, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI186910306, Length=460, Percent_Identity=27.1739130434783, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI186910304, Length=460, Percent_Identity=27.1739130434783, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI71979932, Length=445, Percent_Identity=28.314606741573, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI9790235, Length=448, Percent_Identity=30.5803571428571, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI33286430, Length=259, Percent_Identity=29.7297297297297, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI71999149, Length=419, Percent_Identity=23.8663484486874, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI258645169, Length=387, Percent_Identity=23.5142118863049, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082250, Length=466, Percent_Identity=27.6824034334764, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI2367353, Length=415, Percent_Identity=28.1927710843373, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87081708, Length=426, Percent_Identity=19.2488262910798, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786694, Length=315, Percent_Identity=23.8095238095238, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786302, Length=458, Percent_Identity=22.707423580786, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787890, Length=457, Percent_Identity=22.5382932166302, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=462, Percent_Identity=28.5714285714286, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17568033, Length=466, Percent_Identity=28.9699570815451, Blast_Score=150, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI71990446, Length=456, Percent_Identity=26.5350877192982, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI32566699, Length=399, Percent_Identity=29.8245614035088, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71995388, Length=463, Percent_Identity=26.9978401727862, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71995382, Length=463, Percent_Identity=26.9978401727862, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71982608, Length=450, Percent_Identity=28.2222222222222, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71982612, Length=450, Percent_Identity=27.7777777777778, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71993915, Length=353, Percent_Identity=26.3456090651558, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17532491, Length=474, Percent_Identity=25.5274261603376, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71982623, Length=273, Percent_Identity=29.6703296703297, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI193208714, Length=440, Percent_Identity=23.4090909090909, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI32566695, Length=440, Percent_Identity=23.4090909090909, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17533459, Length=437, Percent_Identity=24.9427917620137, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71987339, Length=328, Percent_Identity=26.219512195122, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321492, Length=403, Percent_Identity=25.5583126550869, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321751, Length=434, Percent_Identity=23.0414746543779, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641993, Length=399, Percent_Identity=28.8220551378446, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI221331183, Length=451, Percent_Identity=31.0421286031042, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI17647653, Length=451, Percent_Identity=31.0421286031042, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24664379, Length=451, Percent_Identity=31.0421286031042, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI21357367, Length=457, Percent_Identity=29.5404814004376, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24641995, Length=399, Percent_Identity=28.8220551378446, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24651635, Length=448, Percent_Identity=27.0089285714286, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24651633, Length=448, Percent_Identity=27.0089285714286, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI45550968, Length=460, Percent_Identity=29.3478260869565, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI19921172, Length=460, Percent_Identity=29.3478260869565, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI221512776, Length=365, Percent_Identity=25.2054794520548, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24666159, Length=365, Percent_Identity=25.2054794520548, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24667468, Length=376, Percent_Identity=25, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281366235, Length=364, Percent_Identity=22.8021978021978, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116007820, Length=364, Percent_Identity=22.8021978021978, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24668806, Length=424, Percent_Identity=23.5849056603774, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356285, Length=424, Percent_Identity=23.5849056603774, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24668802, Length=424, Percent_Identity=23.5849056603774, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007818, Length=385, Percent_Identity=22.5974025974026, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI85725152, Length=385, Percent_Identity=22.5974025974026, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48833; Mature: 48833

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKHHGEQALEKTIGFWTAITVVIGTIIGSGVFVKPSVVLNHAGTSDLAIWAWVVGGILT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEECCCCCHHHHHHHHHHHHHH
LAAGLTIAEVGAQIPKTGGLYAYIRDIYGPFWGFLTGWMQTVIYGPAIIASLSLFFGILV
HHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNFFGIDPDLGIWIGIAAFTFLVILNILGTNAGGAMQTFTTICKLIPVFAIIIFGLLWGK
HHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
EGVFGHNVTSLIENKGEVNFGRAVLATLFAYDGWILLTNLTGEMKNAKRNLPLAMLVGLS
CCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEEEECCCHHHHHHCCCCHHHHHHHH
VVTFAYVLINIAVFKVIPAETLVGLGNTSSAEAAKILFGDLGSKFVNIGVIISIFGCLNG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KIMTFPRIPFAMADDNLLPFAKFISYVSPKFKTPIGAMITMYVVSMILLLLTIVIPEIVN
CEEEECCCCCEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
ADYLSEICIFVIYIFYIASFIGLFILRKQTKGQKRDYSVPLYPIVPIIAMGGGLFIIIST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
LMSDFFGSMLGVLFVVIGIPFYFMLHKKHV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKHHGEQALEKTIGFWTAITVVIGTIIGSGVFVKPSVVLNHAGTSDLAIWAWVVGGILT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEECCCCCHHHHHHHHHHHHHH
LAAGLTIAEVGAQIPKTGGLYAYIRDIYGPFWGFLTGWMQTVIYGPAIIASLSLFFGILV
HHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNFFGIDPDLGIWIGIAAFTFLVILNILGTNAGGAMQTFTTICKLIPVFAIIIFGLLWGK
HHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
EGVFGHNVTSLIENKGEVNFGRAVLATLFAYDGWILLTNLTGEMKNAKRNLPLAMLVGLS
CCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEEEECCCHHHHHHCCCCHHHHHHHH
VVTFAYVLINIAVFKVIPAETLVGLGNTSSAEAAKILFGDLGSKFVNIGVIISIFGCLNG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KIMTFPRIPFAMADDNLLPFAKFISYVSPKFKTPIGAMITMYVVSMILLLLTIVIPEIVN
CEEEECCCCCEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
ADYLSEICIFVIYIFYIASFIGLFILRKQTKGQKRDYSVPLYPIVPIIAMGGGLFIIIST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
LMSDFFGSMLGVLFVVIGIPFYFMLHKKHV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]