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The map label for this gene is arsB [H]

Identifier: 222151732

GI number: 222151732

Start: 1607341

End: 1608633

Strand: Direct

Name: arsB [H]

Synonym: MCCL_1485

Alternate gene names: 222151732

Gene position: 1607341-1608633 (Clockwise)

Preceding gene: 222151731

Following gene: 222151733

Centisome position: 76.46

GC content: 40.37

Gene sequence:

>1293_bases
ATGATGACAGCAGTCGCAATTGCTATATTTCTTATTACGTTAGTCTTTATTATCTGGCAGCCGAAAGGTCTAGACATCGG
TATTACAGCAGTTGTCGGTGCAATCGTTGCAATTCTTACAGGTGTCGTCAGTTTCTCTGATGTACTTGAGGTTACAGATA
TTGTGTGGAATGCCACGCTTACGTTTATCGCAGTGATCATCATCTCGCTTATATTAGATGAGATTGGTTTCTTTGAATGG
GCAGCCATCCATATGGTCCGCGCTTCACACGGTAATGGTTTCAAGATGTTCGTCTATATTATGTTGCTTGGCGCTATTGT
TGCAGCGTTTTTTGCCAATGATGGTGCGGCACTGATATTAACACCGATTGTTCTCGCCATGGTGAGACGTCTCGGGTTCA
ATCAGAAGGTTATCTTCCCGTTTATTATTGCAAGTGGTTTTATCGCAGATACGACGTCACTGCCTTTAATCGTCAGCAAT
CTCGTTAATATCGTCTCTGCGGATTACTTTAACATCGGATTTGTTGAATATGTCAGCCGTATGATCATTCCGAATCTCTT
CTCGCTTCTTGCAAGCATCGTTGTTCTATGGTTATATTTCAGGCAATCGATACCCCGTACATTTAATGCCGATAATATTG
GGACACCTGAAAGTGCAATCAAAGATATGAAACTCTTCAAGATGTCATGGATCGTGCTATTTATTCTTTTCATCGGTTAC
TTAAGCAGTGAATTTATCAATATCCCTGTTTCACTGATTGCAGGAGTCATTACAATTATCTTTATTGTATTAGCAAGCAA
ATCCCCTGCTGTTAACACGAGACAAGTTATTAAAGGGGCACCGTGGAACATCGTATTTTTCTCTATCGGGATGTATCTCG
TCGTCTTCGGGCTTAAGAATGTTGGTATCACGACAGTGCTAGCAGATGTGCTTTCTACGATTTCTACATATGGCCTGTTC
AGCAGCATCATGGGTATGGGATTTATCGCTGCATTCTTATCATCTGTGATGAACAATATGCCAACTGTGTTAATTGATGC
CATTGCAATTGGCCAGTCCGATGCAACTGGATTATTAAAGGAAGGTATGATCTATGCGAACGTTATCGGTTCAGATCTAG
GTCCTAAGATCACACCGATTGGCTCACTTGCCACACTGCTATGGTTACATGTGCTCTCACAAAAAGGCGTGAAGATTTCA
TGGGGAACATATTTTAAAACAGGGATTGTCATCACAATTCCAGTTTTATTTATTACATTGTTCGGACTTTATTTAACATT
AATATTATTTTAA

Upstream 100 bases:

>100_bases
TGAATCACGATAAGCTGAAAGAGATTAACGATCACTTATCTTCACTGAACGCATCGCAGGAAGCATGTATTTGTAACACT
GTGAAAAGAGGTGCGTGCCA

Downstream 100 bases:

>100_bases
AGATTTGAGGGATTTTTATGGAGAAGAAGACACTTTATTTTATTTGTACAGGAAACTCCTGTCGCAGTCAGATGGCTGAA
GGATGGGGAAAGCACATTCT

Product: arsenic efflux pump protein

Products: ADP; phosphate; arsenite [Periplasm] [C]

Alternate protein names: Arsenic efflux pump protein [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MMTAVAIAIFLITLVFIIWQPKGLDIGITAVVGAIVAILTGVVSFSDVLEVTDIVWNATLTFIAVIIISLILDEIGFFEW
AAIHMVRASHGNGFKMFVYIMLLGAIVAAFFANDGAALILTPIVLAMVRRLGFNQKVIFPFIIASGFIADTTSLPLIVSN
LVNIVSADYFNIGFVEYVSRMIIPNLFSLLASIVVLWLYFRQSIPRTFNADNIGTPESAIKDMKLFKMSWIVLFILFIGY
LSSEFINIPVSLIAGVITIIFIVLASKSPAVNTRQVIKGAPWNIVFFSIGMYLVVFGLKNVGITTVLADVLSTISTYGLF
SSIMGMGFIAAFLSSVMNNMPTVLIDAIAIGQSDATGLLKEGMIYANVIGSDLGPKITPIGSLATLLWLHVLSQKGVKIS
WGTYFKTGIVITIPVLFITLFGLYLTLILF

Sequences:

>Translated_430_residues
MMTAVAIAIFLITLVFIIWQPKGLDIGITAVVGAIVAILTGVVSFSDVLEVTDIVWNATLTFIAVIIISLILDEIGFFEW
AAIHMVRASHGNGFKMFVYIMLLGAIVAAFFANDGAALILTPIVLAMVRRLGFNQKVIFPFIIASGFIADTTSLPLIVSN
LVNIVSADYFNIGFVEYVSRMIIPNLFSLLASIVVLWLYFRQSIPRTFNADNIGTPESAIKDMKLFKMSWIVLFILFIGY
LSSEFINIPVSLIAGVITIIFIVLASKSPAVNTRQVIKGAPWNIVFFSIGMYLVVFGLKNVGITTVLADVLSTISTYGLF
SSIMGMGFIAAFLSSVMNNMPTVLIDAIAIGQSDATGLLKEGMIYANVIGSDLGPKITPIGSLATLLWLHVLSQKGVKIS
WGTYFKTGIVITIPVLFITLFGLYLTLILF
>Mature_430_residues
MMTAVAIAIFLITLVFIIWQPKGLDIGITAVVGAIVAILTGVVSFSDVLEVTDIVWNATLTFIAVIIISLILDEIGFFEW
AAIHMVRASHGNGFKMFVYIMLLGAIVAAFFANDGAALILTPIVLAMVRRLGFNQKVIFPFIIASGFIADTTSLPLIVSN
LVNIVSADYFNIGFVEYVSRMIIPNLFSLLASIVVLWLYFRQSIPRTFNADNIGTPESAIKDMKLFKMSWIVLFILFIGY
LSSEFINIPVSLIAGVITIIFIVLASKSPAVNTRQVIKGAPWNIVFFSIGMYLVVFGLKNVGITTVLADVLSTISTYGLF
SSIMGMGFIAAFLSSVMNNMPTVLIDAIAIGQSDATGLLKEGMIYANVIGSDLGPKITPIGSLATLLWLHVLSQKGVKIS
WGTYFKTGIVITIPVLFITLFGLYLTLILF

Specific function: Involved in arsenical resistance. Thought to form the channel of an arsenite pump [H]

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsB family [H]

Homologues:

Organism=Escherichia coli, GI87082277, Length=423, Percent_Identity=58.1560283687943, Blast_Score=477, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802 [H]

Pfam domain/function: PF02040 ArsB [H]

EC number: NA

Molecular weight: Translated: 46743; Mature: 46743

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHC
>Mature Secondary Structure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HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; arsenite [Cytoplasm]; H2O [C]

Specific reaction: ATP + arsenite [Cytoplasm] + H2O = ADP + phosphate + arsenite [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]